Gene: Pml (promyelocytic leukemia) Rattus norvegicus
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Symbol: Pml
Name: promyelocytic leukemia
Description: ENCODES a protein that exhibits cobalt ion binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); apoptotic process (ortholog); branching involved in mammary gland duct morphogenesis (ortholog); PARTICIPATES IN mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; acute myeloid leukemia pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); brain glioblastoma multiforme (ortholog); Carcinoma, Ductal, Breast (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extrinsic component of endoplasmic reticulum membrane (ortholog); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil; bisphenol A
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315713; RGD1562602; similar to promyelocytic leukemia
Orthologs:
Homo sapiens (human) : PML (promyelocytic leukemia)  HGNC
Mus musculus (house mouse) : Pml (promyelocytic leukemia)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Pml (promyelocytic leukemia)
Pan paniscus (bonobo/pygmy chimpanzee) : PML (promyelocytic leukemia)
Canis lupus familiaris (dog) : PML (promyelocytic leukemia)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pml (promyelocytic leukemia)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0863,002,515 - 63,034,310 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0862,778,563 - 62,810,283 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4862,020,438 - 62,051,927 (-)NCBIRGSC3.4rn4RGSC3.4
Celera858,089,954 - 58,121,691 (-)NCBI
Cytogenetic Map8q24NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pml
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1562602
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE