Gene: Pml (promyelocytic leukemia) Rattus norvegicus
Symbol: Pml
Name: promyelocytic leukemia
Description: ENCODES a protein that exhibits cobalt ion binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); apoptotic process (ortholog); branching involved in mammary gland duct morphogenesis (ortholog); PARTICIPATES IN mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; acute myeloid leukemia pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); extrinsic component of endoplasmic reticulum membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315713; RGD1562602; similar to promyelocytic leukemia
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
RGSC Genome Assembly v6.0863,002,515 - 63,034,310-NCBI
Rat Cytogenetic Map8q24 NCBI
RGSC Genome Assembly v5.0862,778,563 - 62,810,283-NCBI
RGSC Genome Assembly v3.4862,020,438 - 62,051,927-NCBI
Rat Celera Assembly858,089,954 - 58,121,691-NCBI

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Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Pml
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1562602
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE