Gene: Cyld (cylindromatosis (turban tumor syndrome)) Rattus norvegicus
Symbol: Cyld
Name: cylindromatosis (turban tumor syndrome)
Description: ENCODES a protein that exhibits Lys63-specific deubiquitinase activity (ortholog); proline-rich region binding (ortholog); protein kinase binding (ortholog); INVOLVED IN necroptotic process (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of NF-kappaB import into nucleus (ortholog); PARTICIPATES IN nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; ASSOCIATED WITH Familial Cylindromatosis (ortholog); Skin Neoplasms (ortholog); Trichoepithelioma Multiple Familial (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); ciliary tip (ortholog); INTERACTS WITH bisphenol A; furan; methapyrilene
Type: protein-coding
Also known as: deubiquitinating enzyme CYLD; LOC100362727; LOC312937; LRRGT00003; probable ubiquitin carboxyl-terminal hydrolase CYLD; probable ubiquitin carboxyl-terminal hydrolase CYLD-like; retinitis pigmentosa 1 (autosomal dominant); retinitis pigmentosa 1 homolog; retinitis pigmentosa 1 homolog (human); Rp1; Rp1h; ubiquitin carboxyl-terminal hydrolase CYLD; ubiquitin thioesterase CYLD; ubiquitin thiolesterase CYLD; ubiquitin-specific-processing protease CYLD
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01919,260,506 - 19,323,817-NCBI
Rat Cytogenetic Map19p11 NCBI
RGSC Genome Assembly v5.01930,298,220 - 30,357,107-NCBI
RGSC Genome Assembly v3.41919,616,209 - 19,619,221-NCBI
Rat Celera Assembly1918,203,184 - 18,261,162-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Cyld
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1308346
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2015-08-11
Status: ACTIVE