Gene: Cdkn2a (cyclin-dependent kinase inhibitor 2A)  Rattus norvegicus

Symbol: Cdkn2a
Name: cyclin-dependent kinase inhibitor 2A
Description: ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); MDM2/MDM4 family protein binding (ortholog); NF-kappaB binding (ortholog); INVOLVED IN aging; response to drug; response to organic cyclic compound; PARTICIPATES IN bladder cancer pathway; cell cycle pathway, mitotic; ceramide signaling pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; Colonic Neoplasms; Endometrial Neoplasms; FOUND IN nucleus; cytoplasm (ortholog); granular component (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Arf; CDK4I; cell cycle inhibitor; cell cycle regulator; Cyclin dependent kinase inhibitor 2A (p16 inhibits CDK4); Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; INK4A; MTS1; p16; p16-INK4; p16-INK4a; p16Cdkn2a; p19ARF
Orthologs: Homo sapiens : CDKN2A (cyclin-dependent kinase inhibitor 2A)  HGNC
Mus musculus : Cdkn2a (cyclin-dependent kinase inhibitor 2A)  MGI
Allele / Splice: Cdkn2a_v1   Cdkn2a_v2  
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map5q32 NCBI
RGSC Genome Assembly v5.05111,556,970 - 111,557,193-NCBI
RGSC Genome Assembly v5.05111,793,604 - 111,801,220-NCBI
RGSC Genome Assembly v3.45108,908,749 - 108,916,380-NCBI
Rat Celera Assembly5102,700,552 - 102,707,724-NCBI
Genome Assembly 3.15108,913,974 - 108,921,606-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)
Related Rat Strains

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cdkn2a
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RGD Object Information
RGD ID: 2323
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-05-28
Status: ACTIVE