Gene: Pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) Rattus norvegicus
Symbol: Pik3ca
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity; insulin receptor substrate binding (ortholog); protein kinase activator activity (ortholog); INVOLVED IN phosphatidylinositol phosphorylation; response to butyrate; response to dexamethasone; PARTICIPATES IN adenosine signaling pathway; altered phosphatidylinositol 3-kinase signaling pathway; altered phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH Polycystic Kidney, Autosomal Recessive; Adenocarcinoma (ortholog); Adenocarcinoma of Esophagus (ortholog); FOUND IN phosphatidylinositol 3-kinase complex; lamellipodium (ortholog); phosphatidylinositol 3-kinase complex, class IA (ortholog); INTERACTS WITH all-trans-retinoic acid; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC116320; p110alpha; phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphoinositide-3-kinase catalytic alpha polypeptide; phosphoinositide-3-kinase, catalytic, alpha polypeptide; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; ptdIns-3-kinase subunit alpha; ptdIns-3-kinase subunit p110-alpha; serine/threonine protein kinase PIK3CA
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02118,831,350 - 118,861,456 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02138,491,967 - 138,521,934 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42118,640,277 - 118,672,440 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12118,603,330 - 118,613,969 (+)NCBI
Celera2110,329,861 - 110,360,075 (+)NCBI
Cytogenetic Map2q24NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Pik3ca
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 620916
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-10-11
Status: ACTIVE