Gene: Smad2 (SMAD family member 2)  Rattus norvegicus

Symbol: Smad2
Name: SMAD family member 2
Description: ENCODES a protein that exhibits transcription factor binding; activating transcription factor binding (ortholog); chromatin binding (ortholog); INVOLVED IN negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction involved in regulation of gene expression; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Carcinoma, Renal Cell (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm; nucleus; protein complex; INTERACTS WITH 2-acetamidofluorene; 2-methoxyethanol; 3H-1,2-dithiole-3-thione
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MAD (mothers against decapentaplegic Drosophila) homolog 2; MAD (mothers against decapentaplegic, Drosophila) homolog 2; MAD homolog 2; MAD homolog 2 (Drosophila); mad-related protein 2; Madh2; MGC156656; mothers against decapentaplegic homolog 2; mothers against DPP homolog 2; SMAD 2; SMAD family member 2
Orthologs: Homo sapiens : SMAD2 (SMAD family member 2)  HGNC
Mus musculus : Smad2 (SMAD family member 2)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map18q12.3 NCBI
RGSC Genome Assembly v5.01871,673,318 - 71,734,563+NCBI
RGSC Genome Assembly v3.41873,180,520 - 73,241,707+NCBI
Rat Celera Assembly1868,382,092 - 68,443,190+NCBI
Genome Assembly 3.11873,253,792 - 73,314,980+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Smad2
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Ensembl Gene
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RGD Object Information
RGD ID: 3031
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE