Annotation (Toggle Detail/Summary View) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | affects expression | ISO | RGD:736865 | 6480464 | Ethinyl Estradiol affects the expression of FGFR2 mRNA | CTD | PMID:20170705 | 17alpha-ethynylestradiol | decreases expression | ISO | RGD:736865 | 6480464 | Ethinyl Estradiol results in decreased expression of FGFR2 mRNA | CTD | PMID:18936297 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of FGFR2 mRNA | CTD | PMID:20170705 | 17beta-estradiol | multiple interactions | ISO | RGD:736865 | 6480464 | ESR2 protein affects the reaction [Estradiol results in decreased expression of FGFR2 mRNA] | CTD | PMID:14699072 | 17beta-estradiol | decreases expression | ISO | RGD:736865 | 6480464 | Estradiol results in decreased expression of FGFR2 mRNA | CTD | PMID:23019147 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of FGFR2 mRNA alternative form; more ... | CTD | PMID:15680359 | 17beta-estradiol | increases expression | ISO | RGD:736865 | 6480464 | Estradiol results in increased expression of FGFR2 protein alternative form | CTD | PMID:18575591 | 17beta-estradiol | increases expression | ISO | RGD:736865 | 6480464 | Estradiol results in increased expression of FGFR2 mRNA alternative form | CTD | PMID:14602803 | 17beta-estradiol | affects expression | ISO | RGD:736865 | 6480464 | Estradiol affects the expression of FGFR2 mRNA | CTD | PMID:14699072 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:10581 | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]; more ... | CTD | PMID:16054899 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:736865 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGFR2 mRNA | CTD | PMID:23152189 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10581 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGFR2 mRNA | CTD | PMID:17586704 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:10581 | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGFR2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGFR2 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10581 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGFR2 mRNA | CTD | PMID:17586704 PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGFR2 mRNA | CTD | PMID:18796159 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10581 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGFR2 mRNA | CTD | PMID:16054899 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10581 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGFR2 mRNA | CTD | PMID:19933214 PMID:17586704 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of FGFR2 mRNA | CTD | PMID:21346803 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGFR2 mRNA | CTD | PMID:20959002 | 3,3',5-triiodo-L-thyronine | increases expression | ISO | RGD:10581 | 6480464 | Triiodothyronine results in increased expression of FGFR2 mRNA | CTD | PMID:16150908 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:10581 | 6480464 | [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]; more ... | CTD | PMID:16054899 | 5-(2-methylpiperazine-1-sulfonyl)isoquinoline | multiple interactions | EXP | | 6480464 | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGFR2 protein] | CTD | PMID:15654655 | 5-fluorouracil | multiple interactions | ISO | RGD:736865 | 6480464 | FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil]; more ... | CTD | PMID:18575591 | acetone | increases expression | ISO | RGD:736865 | 6480464 | Acetone results in increased expression of FGFR2 mRNA | CTD | PMID:12720008 | aflatoxin B1 | decreases expression | ISO | RGD:736865 | 6480464 | Aflatoxin B1 results in decreased expression of FGFR2 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | decreases expression | ISO | RGD:736865 | 6480464 | Tretinoin results in decreased expression of FGFR2 mRNA | CTD | PMID:7680553 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of FGFR2 protein | CTD | PMID:15389522 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FGFR2 mRNA | CTD | PMID:16483693 | benzene | increases expression | ISO | RGD:10581 | 6480464 | Benzene results in increased expression of FGFR2 mRNA | CTD | PMID:15122651 PMID:15120971 | benzene | increases expression | ISO | RGD:10581 | 6480464 | Benzene results in increased expression of FGFR2 mRNA | CTD | PMID:15120971 PMID:15122651 | bis(2-chloroethyl) sulfide | affects expression | EXP | | 6480464 | Mustard Gas affects the expression of FGFR2 mRNA | CTD | PMID:15651846 | bisphenol A | affects expression | ISO | RGD:736865 | 6480464 | bisphenol A affects the expression of FGFR2 mRNA | CTD | PMID:20170705 | cadmium atom | decreases expression | ISO | RGD:10581 | 6480464 | Cadmium results in decreased expression of FGFR2 mRNA | CTD | PMID:22666406 | calcitriol | increases expression | ISO | RGD:736865 | 6480464 | Calcitriol results in increased expression of FGFR2 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | RGD:736865 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of FGFR2 mRNA | CTD | PMID:21592394 | calcitriol | increases expression | ISO | RGD:736865 | 6480464 | Calcitriol results in increased expression of FGFR2 protein | CTD | PMID:12761878 | carbonyl sulfide | decreases expression | EXP | | 6480464 | carbonyl sulfide results in decreased expression of FGFR2 mRNA | CTD | PMID:19395590 | chlorpyrifos | affects expression | EXP | | 6480464 | Chlorpyrifos affects the expression of FGFR2 mRNA | CTD | PMID:18502319 | cisplatin | decreases expression | ISO | RGD:736865 | 6480464 | Cisplatin results in decreased expression of FGFR2 mRNA | CTD | PMID:21603599 | cisplatin | affects response to substance | ISO | RGD:736865 | 6480464 | FGFR2 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | clofibrate | multiple interactions | ISO | RGD:10581 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of FGFR2 mRNA; more ... | CTD | PMID:17585979 | curcumin | decreases expression | ISO | RGD:736865 | 6480464 | Curcumin results in decreased expression of FGFR2 mRNA | CTD | PMID:15713895 | dexamethasone | multiple interactions | ISO | RGD:10581 | 6480464 | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA; more ... | CTD | PMID:16054899 | dexamethasone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of FGFR2 mRNA] | CTD | PMID:20032058 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of FGFR2 mRNA | CTD | PMID:20032058 | diarsenic trioxide | decreases expression | ISO | RGD:736865 | 6480464 | arsenic trioxide results in decreased expression of FGFR2 mRNA | CTD | PMID:15761015 | diazepam | decreases expression | ISO | RGD:736865 | 6480464 | Diazepam results in decreased expression of FGFR2 mRNA | CTD | PMID:19114084 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of FGFR2 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of FGFR2 mRNA | CTD | PMID:19464577 PMID:21266533 | disodium selenite | multiple interactions | ISO | RGD:10581 | 6480464 | Sodium Selenite promotes the reaction [Hydrogen Peroxide results in decreased expression of FGFR2 mRNA] | CTD | PMID:17997286 | ethanol | increases expression | ISO | RGD:736865 | 6480464 | Ethanol results in increased expression of FGFR2 mRNA | CTD | PMID:12720008 | fluprostenol | decreases expression | EXP | | 6480464 | fluprostenol results in decreased expression of FGFR2 mRNA | CTD | PMID:15654655 | genistein | multiple interactions | ISO | RGD:736865 | 6480464 | ESR2 promotes the reaction [Genistein results in increased expression of FGFR2 protein] | CTD | PMID:20884965 | genistein | decreases expression | ISO | RGD:736865 | 6480464 | Genistein results in decreased expression of FGFR2 mRNA | CTD | PMID:23019147 | genistein | increases expression | ISO | RGD:736865 | 6480464 | Genistein results in increased expression of FGFR2 protein | CTD | PMID:20884965 | heparan sulfate | decreases activity | ISO | RGD:736865 | 6480464 | Heparitin Sulfate analog results in decreased activity of FGFR2 protein mutant form | CTD | PMID:16373332 | heparin | multiple interactions | ISO | RGD:736865 | 6480464 | [Heparin analog binds to FGFR2 protein alternative form] which binds to and results in increased activity of FGF1 protein | CTD | PMID:16219767 | heparin | affects binding | EXP | | 6480464 | [Heparin binds to FGFR2 protein alternative form] which binds to FGF2 protein; more ... | CTD | PMID:10860838 | heparin | multiple interactions | ISO | RGD:10581 | 6480464 | Heparin promotes the reaction [FGFR2 protein binds to FGF2 protein] | CTD | PMID:1373495 | heparin | affects activity | ISO | RGD:10581 | 6480464 | Heparin affects the activity of FGFR2 protein | CTD | PMID:1373495 | heparin | multiple interactions | ISO | RGD:736865 | 6480464 | Heparin promotes the reaction [FGF10 protein binds to FGFR2 protein] | CTD | PMID:15632068 | hydrogen peroxide | affects expression | ISO | RGD:736865 | 6480464 | Hydrogen Peroxide affects the expression of FGFR2 mRNA | CTD | PMID:20044591 | hydrogen peroxide | multiple interactions | ISO | RGD:10581 | 6480464 | Sodium Selenite promotes the reaction [Hydrogen Peroxide results in decreased expression of FGFR2 mRNA] | CTD | PMID:17997286 | hydrogen peroxide | decreases expression | ISO | RGD:10581 | 6480464 | Hydrogen Peroxide results in decreased expression of FGFR2 mRNA | CTD | PMID:17997286 | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of FGFR2 mRNA | CTD | PMID:21396975 | menadione | affects expression | ISO | RGD:736865 | 6480464 | Vitamin K 3 affects the expression of FGFR2 mRNA | CTD | PMID:20044591 | N-(1-naphthyl)ethylenediamine | increases expression | ISO | RGD:10581 | 6480464 | N-(1-naphthyl)ethylenediamine results in increased expression of FGFR2 mRNA | CTD | PMID:17311802 | N-methyl-N-nitrosurea | multiple interactions | EXP | | 6480464 | Methylnitrosourea results in increased expression of and affects the localization of FGFR2 protein | CTD | PMID:15581186 | nickel sulfate | increases expression | ISO | RGD:736865 | 6480464 | nickel sulfate results in increased expression of FGFR2 protein | CTD | PMID:12930308 | nitroglycerin | increases expression | EXP | | 6480464 | Nitroglycerin results in increased expression of FGFR2 mRNA | CTD | PMID:12102619 | oxaliplatin | increases expression | ISO | RGD:736865 | 6480464 | oxaliplatin results in increased expression of FGFR2 mRNA | CTD | PMID:17762391 | paracetamol | multiple interactions | ISO | RGD:10581 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of FGFR2 mRNA; more ... | CTD | PMID:17585979 | phenytoin | increases expression | ISO | RGD:736865 | 6480464 | Phenytoin results in increased expression of FGFR2 mRNA; more ... | CTD | PMID:11352631 | phorbol 13-acetate 12-myristate | multiple interactions | EXP | | 6480464 | Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGFR2 protein] | CTD | PMID:15654655 | pirinixic acid | decreases expression | ISO | RGD:10581 | 6480464 | pirinixic acid results in decreased expression of FGFR2 mRNA | CTD | PMID:20813756 | pirinixic acid | increases expression | ISO | RGD:10581 | 6480464 | pirinixic acid results in increased expression of FGFR2 mRNA | CTD | PMID:18301758 | pirinixic acid | multiple interactions | ISO | RGD:736865 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of FGFR2 mRNA | CTD | PMID:19710929 | progesterone | affects expression | ISO | RGD:10581 | 6480464 | Progesterone affects the expression of FGFR2 mRNA | CTD | PMID:17251523 | prostaglandin F2alpha | multiple interactions | EXP | | 6480464 | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGFR2 protein]; more ... | CTD | PMID:15654655 | prostaglandin F2alpha | affects localization | EXP | | 6480464 | Dinoprost affects the localization of FGFR2 protein | CTD | PMID:15654655 | prostaglandin F2alpha | decreases expression | EXP | | 6480464 | Dinoprost results in decreased expression of FGFR2 mRNA | CTD | PMID:15654655 | prostaglandin F2alpha | multiple interactions | EXP | | 6480464 | Dinoprost affects the localization of [FGF2 protein binds to FGFR2 protein]; more ... | CTD | PMID:16365892 | raloxifene | multiple interactions | ISO | RGD:736865 | 6480464 | [Raloxifene co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA | CTD | PMID:19059307 | rosiglitazone | multiple interactions | ISO | RGD:10581 | 6480464 | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA; more ... | CTD | PMID:16054899 | suramin | multiple interactions | ISO | RGD:736865 | 6480464 | Suramin inhibits the reaction [FGF7 protein binds to FGFR2 protein] | CTD | PMID:15733146 | tamoxifen | multiple interactions | ISO | RGD:736865 | 6480464 | FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Tamoxifen] | CTD | PMID:18575591 | tamoxifen | multiple interactions | ISO | RGD:736865 | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA | CTD | PMID:19059307 | testosterone | multiple interactions | ISO | RGD:736865 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of FGFR2 mRNA | CTD | PMID:21592394 | testosterone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of FGFR2 mRNA] | CTD | PMID:20032058 | testosterone | decreases expression | ISO | RGD:10581 | 6480464 | Testosterone results in decreased expression of FGFR2 mRNA | CTD | PMID:7536664 | testosterone | decreases expression | ISO | RGD:736865 | 6480464 | Testosterone results in decreased expression of FGFR2 mRNA | CTD | PMID:21592394 | tetrachloromethane | decreases expression | ISO | RGD:10581 | 6480464 | Carbon Tetrachloride results in decreased expression of FGFR2 mRNA | CTD | PMID:17484886 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of FGFR2 mRNA | CTD | PMID:17692400 PMID:16644059 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of FGFR2 mRNA | CTD | PMID:16644059 PMID:17692400 | trimellitic anhydride | decreases expression | ISO | RGD:10581 | 6480464 | trimellitic anhydride results in decreased expression of FGFR2 mRNA | CTD | PMID:19042947 | vanadyl sulfate | increases expression | ISO | RGD:736865 | 6480464 | vanadyl sulfate results in increased expression of FGFR2 mRNA | CTD | PMID:16330358 | vanillin | decreases expression | ISO | RGD:736865 | 6480464 | vanillin results in decreased expression of FGFR2 mRNA | CTD | PMID:17178418 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Endocytosis |
| MAPK signaling pathway | |
| Pathways in cancer | |
| PI3K-Akt signaling pathway | |
| Prostate cancer | |
| Regulation of actin cytoskeleton | |
| Pathway Interaction Database | FGF signaling pathway (PID:200220) |
Phenotype Annotations
Disease Annotations
Gene-Chemical Interaction Annotations
|
|
|
Gene Ontology Annotations
|
|
|
|
|
|
|
Molecular Pathway Annotations
|
|
| External Database Links | |
| KEGG Pathway | Endocytosis |
| MAPK signaling pathway | |
| Pathways in cancer | |
| PI3K-Akt signaling pathway | |
| Prostate cancer | |
| Regulation of actin cytoskeleton | |
| Pathway Interaction Database | FGF signaling pathway (PID:200220) |
Phenotype Annotations
|
|
References - curated| 1. |
Agrotis A, etal., J Biol Chem. 2004 Oct 1;279(40):42221-9. Epub 2004 Jul 30. |
| 2. |
Andreou A, etal., Am J Med Genet A. 2006 Oct 15;140(20):2245-7. |
| 3. |
Barge-Schaapveld DQ, etal., Pediatr Neurol. 2011 Apr;44(4):303-7. |
| 4. |
Billottet C, etal., Mol Biol Cell. 2004 Oct;15(10):4725-34. Epub 2004 Jul 28. |
| 5. |
Cinaroglu A, etal., J Neurosci Res. 2005 Feb 1;79(3):329-39. |
| 6. |
Claus P, etal., J Biol Chem 2003 Jan 3;278(1):479-85. |
| 7. |
Diez de Medina SG, etal., Oncogene. 1997 Jan 23;14(3):323-30. |
| 8. |
Drummond AE, etal., Endocrinology. 2007 Aug;148(8):3711-21. Epub 2007 May 10. |
| 9. |
Dutt A, etal., Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8713-7. Epub 2008 Jun 13. |
| 10. |
Easton DF, etal., Nature. 2007 Jun 28;447(7148):1087-93. |
| 11. |
Fonseca R, etal., Am J Med Genet A. 2008 Mar 1;146A(5):658-60. |
| 12. |
GOA data from the GO Consortium |
| 13. |
Hunter DJ, etal., Nat Genet. 2007 Jul;39(7):870-4. Epub 2007 May 27. |
| 14. |
Jin C, etal., Cancer Res. 2003 Dec 15;63(24):8784-90. |
| 15. |
Jones RB, etal., J Biol Chem. 2001 Feb 9;276(6):4158-67. Epub 2000 Oct 20. |
| 16. |
Leung HY, etal., Oncogene. 1997 Aug 28;15(9):1115-20. |
| 17. |
Manavi M, etal., Gynecol Oncol. 2007 May;105(2):418-26. Epub 2007 Feb 15. |
| 18. |
Matsubara A, etal., Cancer Res. 1998 Apr 1;58(7):1509-14. |
| 19. |
McCann E, etal., Am J Med Genet A. 2005 Oct 15;138A(3):278-81. |
| 20. |
McGrath M, etal., Int J Cancer. 2008 Sep 10. |
| 21. |
Mehta P, etal., BJU Int. 2000 Oct;86(6):681-5. |
| 22. |
MGD data from the GO Consortium |
| 23. |
Naimi B, etal., Prostate. 2002 Aug 1;52(3):245-52. |
| 24. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 25. |
Online Mendelian Inheritance in Man, OMIM (TM). |
| 26. |
Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology |
| 27. |
Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 28. |
Pollock PM, etal., Oncogene. 2007 Nov 1;26(50):7158-62. Epub 2007 May 21. |
| 29. |
RGD automated data pipeline |
| 30. |
RGD automated import pipeline for gene-chemical interactions |
| 31. |
RGD Automated Pipelines |
| 32. |
Ricol D, etal., Oncogene. 1999 Dec 2;18(51):7234-43. |
| 33. |
Rouzier C, etal., Pediatr Blood Cancer. 2008 Mar;50(3):696-8. |
| 34. |
Savagner P, etal., Mol Biol Cell 1994 Aug;5(8):851-62. |
| 35. |
Slavotinek A, etal., Am J Med Genet A. 2009 Aug;149A(8):1814-7. |
| 36. |
Steele IA, etal., Oncogene. 2001 Sep 13;20(41):5878-87. |
| 37. |
Taniguchi F, etal., Fertil Steril. 2008 Feb;89(2):478-80. Epub 2007 May 4. |
| 38. |
Yan G, etal., Biochem Biophys Res Commun 1993 Jul 15;194(1):512-8. |
| 39. |
Yu JE, etal., Clin Genet. 2009 Sep;76(3):287-91. Epub 2009 Jul 17. |
| 40. |
Zhao ZZ, etal., Hum Reprod. 2008 Jul;23(7):1661-8. Epub 2008 Feb 18. |
References - uncurated| PubMed | 11834506 |
| 11891329 | |
| 12608893 | |
| 12828933 | |
| 12947022 | |
| 14645542 | |
| 15065023 | |
| 15126509 | |
| 15601847 | |
| 15684416 | |
| 16856175 | |
| 16963563 | |
| 17708356 | |
| 18039182 | |
| 18363829 | |
| 19053057 | |
| 19103595 | |
| 19410646 | |
| 21691921 | |
| 21994076 | |
| 8875318 | |
| 8889548 | |
| 9528792 |
RGD Disease Portals| Fgfr2 has been annotated in the following RGD Disease Portals. |
|||||||
![]() |
| ||||||
![]() |
| ||||||
![]() |
| ||||||
![]() |
| ||||||
![]() |
| ||||||
![]() |
| ||||||
![]() |
| ||||||
Comparative Map Data| Fgfr2 (Rattus norvegicus) |
|
|||||||||||||||||||||||||||||||||||
| FGFR2 (Homo sapiens) |
|
|||||||||||||||||||||||||||||||||||
| Fgfr2 (Mus musculus) |
|
Position Markers| D1Smu5 |
|
||||||||||||||||||||||||||||||
| RH11106 |
|
||||||||||||||||||||||||||||||
| RH143520 |
|
||||||||||||||||||||||||||||||
| RH140672 |
|
||||||||||||||||||||||||||||||
| BM383187 |
|
||||||||||||||||||||||||||||||
| PMC20217P1 |
|
||||||||||||||||||||||||||||||
| Fgfr2 |
|
QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001109892 | (Get FASTA) | Search GEO for Microarray Profiles |
| NM_001109893 | (Get FASTA) | Search GEO for Microarray Profiles | |
| NM_001109894 | (Get FASTA) | Search GEO for Microarray Profiles | |
| NM_001109895 | (Get FASTA) | Search GEO for Microarray Profiles | |
| NM_001109896 | (Get FASTA) | Search GEO for Microarray Profiles | |
| NM_012712 | (Get FASTA) | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR06008931 | (Get FASTA) | Search GEO for Microarray Profiles |
| AABR06008932 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06008933 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06008934 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06008935 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01008642 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01008643 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01008644 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01008645 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01008646 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01008647 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF147757 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF294649 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF294650 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF456422 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AJ312745 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AW531062 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BF420170 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CB716134 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CB769194 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CB777398 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CB780941 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CF109832 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473956 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CO397781 | (Get FASTA) | Search GEO for Microarray Profiles | |
| D83494 | (Get FASTA) | Search GEO for Microarray Profiles | |
| D83495 | (Get FASTA) | Search GEO for Microarray Profiles | |
| DV718561 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19104 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19105 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19107 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19108 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19109 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19110 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19111 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19112 | (Get FASTA) | Search GEO for Microarray Profiles | |
| U59800 | (Get FASTA) | Search GEO for Microarray Profiles | |
| Z35138 | (Get FASTA) | Search GEO for Microarray Profiles | |
| Z35139 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_012712 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_036844 | ||||||||||||||||||||
| Peptide Label: | isoform a | ||||||||||||||||||||
| Position: |
|
| RefSeq Acc Id: | NM_001109892 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001103362 | ||||||||||||||||||||
| Peptide Label: | isoform b | ||||||||||||||||||||
| Position: |
|
| RefSeq Acc Id: | NM_001109893 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001103363 | ||||||||||||||||||||
| Peptide Label: | isoform c | ||||||||||||||||||||
| Position: |
|
| RefSeq Acc Id: | NM_001109894 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001103364 | ||||||||||||||||||||
| Peptide Label: | isoform d | ||||||||||||||||||||
| Position: |
|
| RefSeq Acc Id: | NM_001109895 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001103365 | ||||||||||||||||||||
| Peptide Label: | isoform e | ||||||||||||||||||||
| Position: |
|
| RefSeq Acc Id: | NM_001109896 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001103366 | ||||||||||||||||||||
| Peptide Label: | isoform f | ||||||||||||||||||||
| Position: |
|
Protein Sequences| Protein RefSeqs | NP_001103362 | (Get FASTA) |
| NP_001103363 | (Get FASTA) | |
| NP_001103364 | (Get FASTA) | |
| NP_001103365 | (Get FASTA) | |
| NP_001103366 | (Get FASTA) | |
| NP_036844 | (Get FASTA) | |
| GenBank Protein | AAA02628 | (Get FASTA) |
| AAA02629 | (Get FASTA) | |
| AAA02690 | (Get FASTA) | |
| AAA02691 | (Get FASTA) | |
| AAA02692 | (Get FASTA) | |
| AAA02693 | (Get FASTA) | |
| AAA02694 | (Get FASTA) | |
| AAB02867 | (Get FASTA) | |
| AAB03225 | (Get FASTA) | |
| AAD31529 | (Get FASTA) | |
| AAD31530 | (Get FASTA) | |
| AAG31575 | (Get FASTA) | |
| AAG31576 | (Get FASTA) | |
| AAL77411 | (Get FASTA) | |
| AAL77412 | (Get FASTA) | |
| BAA77278 | (Get FASTA) | |
| BAA77279 | (Get FASTA) | |
| CAA84510 | (Get FASTA) | |
| CAA84511 | (Get FASTA) | |
| CAC37408 | (Get FASTA) | |
| EDM17149 | (Get FASTA) | |
| EDM17150 | (Get FASTA) | |
| EDM17151 | (Get FASTA) |
Strain Sequence Variants
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000016374 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000022253 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000022331 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSRNOP00000059005 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSRNOP00000061479 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000022253 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000022331 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSRNOT00000065448 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSRNOT00000068183 | ENTREZGENE, UniProtKB/TrEMBL | |
| Entrez Gene | 25022 | ENTREZGENE |
| Gene3D-CATH | 0.10 | UniProtKB/TrEMBL |
| HomoloGene Group ID | 22566 | ENTREZGENE |
| InterPro | Ig-like_dom | UniProtKB/TrEMBL |
| Ig-like_fold | UniProtKB/TrEMBL | |
| Ig_I-set | UniProtKB/TrEMBL | |
| Ig_sub2 | UniProtKB/TrEMBL | |
| Kinase-like_dom | UniProtKB/TrEMBL | |
| Prot_kinase_cat_dom | UniProtKB/TrEMBL | |
| Protein_kinase_ATP_BS | UniProtKB/TrEMBL | |
| Ser-Thr/Tyr_kinase_cat_dom | UniProtKB/TrEMBL | |
| Tyr_kinase_AS | UniProtKB/TrEMBL | |
| Tyr_kinase_cat_dom | UniProtKB/TrEMBL | |
| Tyr_kinase_fibroblast_GF_rcpt | UniProtKB/TrEMBL | |
| IPI | IPI00206890 | UniProtKB/TrEMBL |
| IPI00206914 | UniProtKB/TrEMBL | |
| IPI00206918 | UniProtKB/TrEMBL | |
| IPI00876571 | UniProtKB/TrEMBL | |
| IPI00876585 | UniProtKB/TrEMBL | |
| IPI00876616 | UniProtKB/TrEMBL | |
| IPI00876631 | UniProtKB/TrEMBL | |
| KEGG Report | rno:25022 | ENTREZGENE, UniProtKB/TrEMBL |
| Pfam | I-set | UniProtKB/TrEMBL |
| Pkinase_Tyr | UniProtKB/TrEMBL | |
| PIRSF | FGFR | UniProtKB/TrEMBL |
| PRINTS | TYRKINASE | UniProtKB/TrEMBL |
| PROSITE | IG_LIKE | UniProtKB/TrEMBL |
| PROTEIN_KINASE_ATP | UniProtKB/TrEMBL | |
| PROTEIN_KINASE_DOM | UniProtKB/TrEMBL | |
| PROTEIN_KINASE_TYR | UniProtKB/TrEMBL | |
| SMART | IGc2 | UniProtKB/TrEMBL |
| TyrKc | UniProtKB/TrEMBL | |
| Superfamily-SCOP | Kinase_like | UniProtKB/TrEMBL |
| UniGene | Rn.12732 | ENTREZGENE |
| UniProt | F1LN06_RAT | UniProtKB/TrEMBL |
| F1LNW0_RAT | UniProtKB/TrEMBL | |
| F1LRU8_RAT | UniProtKB/TrEMBL | |
| F1LSG7_RAT | UniProtKB/TrEMBL | |
| Q63236_RAT | UniProtKB/TrEMBL | |
| Q63237_RAT | UniProtKB/TrEMBL | |
| Q63238_RAT | UniProtKB/TrEMBL | |
| Q63239_RAT | UniProtKB/TrEMBL | |
| Q63240_RAT | UniProtKB/TrEMBL | |
| Q63241_RAT | UniProtKB/TrEMBL | |
| Q63242_RAT | UniProtKB/TrEMBL | |
| Q9R2A0_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2002-06-10 | Fgfr2 | fibroblast growth factor receptor 2 | Name updated | 1488 | APPROVED |
| More on Fgfr2 | |
![]() |
Entrez Gene |
![]() |
Ensembl Gene |
![]() | Genome Browser |
![]() |
NCBI Map Viewer |
![]() |
Vista |
![]() |
Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 2611 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




