Gene: Insr (insulin receptor) Rattus norvegicus
Symbol: Insr
Name: insulin receptor
Description: ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; insulin binding; insulin receptor substrate binding; INVOLVED IN cerebellum development; fat cell differentiation; glucose homeostasis; PARTICIPATES IN altered leptin system pathway; insulin signaling pathway; altered insulin signaling pathway; ASSOCIATED WITH Alzheimer Disease; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; FOUND IN cytosol; endosome; intracellular membrane-bounded organelle; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: insulin receptor preproprotein; IR
Homo sapiens (human) : INSR (insulin receptor)  HGNC
Mus musculus (house mouse) : Insr (insulin receptor)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Insr (insulin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : INSR (insulin receptor)
Canis lupus familiaris (dog) : INSR (insulin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Insr (insulin receptor)
more info ...
Is Marker For: Strains:   LEW-Tg(FH1t(Insr)UTG)87Hrjb   LEW-Tg(FH1t(Insr)UTG)4Hrjb  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0121,682,527 - 1,816,414 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0123,848,670 - 3,989,302 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4122,934,967 - 3,087,691 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1122,934,966 - 3,087,691 (+)NCBI
Celera123,053,590 - 3,185,991 (-)NCBI
Cytogenetic Map12p12NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Insr
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2917
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-04-11
Status: ACTIVE