Gene: Insr (insulin receptor) Rattus norvegicus
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Symbol: Insr
Name: insulin receptor
Description: ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; insulin binding; insulin receptor substrate binding; INVOLVED IN cerebellum development; fat cell differentiation; glucose homeostasis; PARTICIPATES IN altered leptin system pathway; insulin signaling pathway; altered insulin signaling pathway; ASSOCIATED WITH Alzheimer Disease; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; FOUND IN cytosol; endosome; intracellular membrane-bounded organelle; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 9-cis-retinoic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: insulin receptor preproprotein; IR
Orthologs:
Is Marker For: Strains:   LEW-Tg(FH1t(Insr)UTG)87Hrjb   LEW-Tg(FH1t(Insr)UTG)4Hrjb  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0121,682,527 - 1,816,414 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0123,848,670 - 3,989,302 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4122,934,967 - 3,087,691 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1122,934,966 - 3,087,691 (+)NCBI
Celera123,053,590 - 3,185,991 (-)NCBI
Cytogenetic Map12p12NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Insr
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2917
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-22
Status: ACTIVE