Gene: Afp (alpha-fetoprotein) Rattus norvegicus
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Symbol: Afp
Name: alpha-fetoprotein
Description: ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN animal organ regeneration; liver development; pancreas development; PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH alpha-Fetoprotein Deficiency (ortholog); Breast Neoplasms (ortholog); Carcinoma, Embryonal (ortholog); FOUND IN cytoplasm; extracellular space; INTERACTS WITH (+)-taxifolin; (S)-naringenin; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1-fetoprotein; alpha-fetoglobulin; chloride intracellular channel 6
Orthologs:
Homo sapiens (human) : AFP (alpha fetoprotein)  HGNC  AGR
Mus musculus (house mouse) : Afp (alpha fetoprotein)  MGI  AGR
Pan paniscus (bonobo/pygmy chimpanzee) : AFP (alpha fetoprotein)
Canis lupus familiaris (dog) : AFP (alpha fetoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Afp (alpha fetoprotein)
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Is Marker For: QTLs:   Scl11  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01419,141,755 - 19,159,919 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01419,049,096 - 19,067,260 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41419,092,563 - 19,110,728 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11419,092,562 - 19,110,728 (-)NCBI
Celera1416,939,827 - 16,957,879 (-)NCBICelera
Cytogenetic Map14p22NCBI
RH 3.4 Map14214.49RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Afp
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2065
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE