Gene: Cyp2e1 (cytochrome P450, family 2, subfamily e, polypeptide 1)  Rattus norvegicus
Symbol: Cyp2e1
Name: cytochrome P450, family 2, subfamily e, polypeptide 1
Description: ENCODES a protein that exhibits oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; enzyme binding (ortholog); heme binding (ortholog); INVOLVED IN oxidation-reduction process; response to drug; response to ethanol; PARTICIPATES IN arachidonic acid metabolic pathway; linoleic acid metabolic pathway; phase I biotransformation pathway via cytochrome P450; ASSOCIATED WITH Depressive Disorder; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; FOUND IN Golgi membrane; intracellular membrane-bounded organelle; intrinsic to endoplasmic reticulum membrane; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-carnitine; (S)-nicotine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4-nitrophenol 2-hydroxylase; Cyp2e; CYPIIE1; cytochrome P450 2E1; Cytochrome P450 subfamily 2e1 (ethanol-inducible); cytochrome P450 subfamily 2e1 (ethanol-inducible); cytochrome P450, family 2, subfamily e, polypeptide 1; cytochrome P450, subfamily 2E, polypeptide 1; cytochrome P450, subfamily 2e1 (ethanol-inducible); cytochrome P450-J; cytochrome P450RLM6; P450-J; P450RLM6
Orthologs: Homo sapiens : CYP2E1 (cytochrome P450, family 2, subfamily E, polypeptide 1)  HGNC
Mus musculus : Cyp2e1 (cytochrome P450, family 2, subfamily e, polypeptide 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map1q41-q42 NCBI
RGSC Genome Assembly v5.01220,406,329 - 220,416,726+NCBI
RGSC Genome Assembly v3.41200,918,521 - 200,928,919+NCBI
Rat Celera Assembly1193,484,404 - 193,494,772+NCBI
Genome Assembly 3.11201,068,525 - 201,078,911+NCBI
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RGD Object Information
RGD ID: 2475
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE



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