Gene: Smad7 (SMAD family member 7)  Rattus norvegicus

Symbol: Smad7
Name: SMAD family member 7
Description: ENCODES a protein that exhibits ubiquitin protein ligase binding; activin binding (ortholog); beta-catenin binding (ortholog); INVOLVED IN intracellular signal transduction; negative regulation of transcription, DNA-dependent; regulation of transforming growth factor beta receptor signaling pathway; PARTICIPATES IN altered transforming growth factor-beta Smad dependent signaling pathway; Bone morphogenetic proteins signaling pathway; colorectal cancer pathway; ASSOCIATED WITH Nephritis; Colorectal Neoplasms (ortholog); Endometrial Neoplasms (ortholog); FOUND IN catenin complex (ortholog); cell-cell adherens junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MAD (mothers against decapentaplegic Drosophila) homolog 7; MAD (mothers against decapentaplegic, Drosophila) homolog 7; MAD homolog 7; MAD homolog 7 (Drosophila); Madh7; mothers against decapentaplegic homolog 7; mothers against DPP homolog 7; SMAD 7; SMAD family member 7
Orthologs: Homo sapiens : SMAD7 (SMAD family member 7)  HGNC
Mus musculus : Smad7 (SMAD family member 7)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map18q12.3 NCBI
RGSC Genome Assembly v5.01870,530,559 - 70,558,927+NCBI
RGSC Genome Assembly v3.41872,294,803 - 72,323,354+NCBI
Rat Celera Assembly1867,155,575 - 67,183,461+NCBI
Genome Assembly 3.11872,368,075 - 72,396,625+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Smad7
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 69314
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2013-05-28
Status: ACTIVE