Gene: Serpina1 (serpin family A member 1) Rattus norvegicus
Symbol: Serpina1
Name: serpin family A member 1
Description: ENCODES a protein that exhibits endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; glycoprotein binding (ortholog); INVOLVED IN inflammatory response; negative regulation of serine-type endopeptidase activity; response to chromate; PARTICIPATES IN forkhead class A signaling pathway; coagulation cascade pathway; complement system pathway; ASSOCIATED WITH Asthma; Burns; Drug-Induced Liver Injury; FOUND IN extracellular space; endoplasmic reticulum (ortholog); extracellular exosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AAT; alpha-1-antiproteinase; alpha-1-antitrypsin (protease inhibitor); alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; Pi; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine protease inhibitor alpha 1; serpin A1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Spi1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06127,610,241 - 127,632,265 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.06136,828,856 - 136,850,880 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.46127,998,617 - 128,021,719 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16128,002,364 - 128,025,466 (-)NCBI
Celera6120,346,394 - 120,368,519 (-)NCBI
Cytogenetic Map6q32NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Serpina1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3326
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-09-02
Status: ACTIVE