Gene: Add1 (adducin 1) Rattus norvegicus
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Symbol: Add1
Name: adducin 1
Description: ENCODES a protein that exhibits T cell receptor binding; actin filament binding (ortholog); cadherin binding (ortholog); INVOLVED IN cellular response to retinoic acid; negative regulation of actin filament polymerization; positive regulation of angiogenesis; ASSOCIATED WITH increased systemic arterial systolic blood pressure; ASSOCIATED WITH Epilepsy, Temporal Lobe; Hypertension; Atherosclerosis (ortholog); FOUND IN dendrite; dendritic spine; perinuclear region of cytoplasm; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adducin 1 (alpha); adducin 1, alpha; alpha-ADD; alpha-adducin; erythrocyte adducin subunit alpha; MGC124621
Orthologs:
Homo sapiens (human) : ADD1 (adducin 1)  HGNC  AGR
Mus musculus (house mouse) : Add1 (adducin 1 (alpha))  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Add1 (adducin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADD1 (adducin 1)
Canis lupus familiaris (dog) : ADD1 (adducin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Add1 (adducin 1)
more info ...
Is Marker For: Strains:   MHS/N  
QTLs:   Bp59  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01481,367,466 - 81,426,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01482,054,922 - 82,114,066 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,750,430 - 81,808,919 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11481,754,353 - 81,784,555 (-)NCBI
Celera1475,033,169 - 75,091,638 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Add1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2041
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE