Gene: Cdk12 (cyclin-dependent kinase 12) Rattus norvegicus
Analyze
Symbol: Cdk12
Name: cyclin-dependent kinase 12
Description: ENCODES a protein that exhibits cyclin binding; protein kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN regulation of RNA splicing; RNA splicing; negative regulation of stem cell differentiation (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH Adenocarcinoma of Lung (ortholog); lung adenocarcinoma (ortholog); Smith-Magenis Syndrome (ortholog); FOUND IN nuclear cyclin-dependent protein kinase holoenzyme complex; nuclear speck; cyclin K-CDK12 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDC2-related kinase 7; Cdc2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; cell division cycle 2-related protein kinase 7; cell division protein kinase 12; Crk7; CrkRS; cyclin-dependent kinase 12 isoform; Pksc; protein kinase for splicing component; similar to human CrkRS: CDC2-related protein kinase 7
Orthologs:
Homo sapiens (human) : CDK12 (cyclin dependent kinase 12)  HGNC  AGR
Mus musculus (house mouse) : Cdk12 (cyclin-dependent kinase 12)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Cdk12 (cyclin dependent kinase 12)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK12 (cyclin dependent kinase 12)
Canis lupus familiaris (dog) : CDK12 (cyclin dependent kinase 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk12 (cyclin dependent kinase 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,157,186 - 86,210,657 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01085,953,855 - 86,019,907 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41086,972,428 - 87,027,794 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11086,986,797 - 87,036,966 (+)NCBI
Celera1081,950,642 - 82,003,549 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cdk12
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621111
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE