Gene: Cdk12 (cyclin-dependent kinase 12) Rattus norvegicus
Symbol: Cdk12
Name: cyclin-dependent kinase 12
Description: ENCODES a protein that exhibits cyclin binding; protein kinase activity (ortholog); RNA polymerase II carboxy-terminal domain kinase activity (ortholog); INVOLVED IN regulation of RNA splicing; RNA splicing; phosphorylation of RNA polymerase II C-terminal domain (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN nuclear cyclin-dependent protein kinase holoenzyme complex; nuclear speck; cyclin K-CDK12 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDC2-related kinase 7; Cdc2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; cell division cycle 2-related protein kinase 7; cell division protein kinase 12; Crk7; CrkRS; cyclin-dependent kinase 12 isoform; Pksc; protein kinase for splicing component; similar to human CrkRS: CDC2-related protein kinase 7
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,157,188 - 86,222,535 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01085,953,855 - 86,019,907 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41086,972,428 - 87,027,794 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11086,986,797 - 87,036,966 (+)NCBI
Celera1081,950,642 - 82,003,549 (+)NCBI
Cytogenetic Map10q31NCBImapview
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cdk12
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621111
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-04-12
Status: ACTIVE