Gene: Cdk12 (cyclin-dependent kinase 12) Rattus norvegicus
Symbol: Cdk12
Name: cyclin-dependent kinase 12
Description: ENCODES a protein that exhibits cyclin binding; protein kinase activity (ortholog); RNA polymerase II carboxy-terminal domain kinase activity (ortholog); INVOLVED IN regulation of RNA splicing; RNA splicing; phosphorylation of RNA polymerase II C-terminal domain (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN nuclear cyclin-dependent protein kinase holoenzyme complex; nuclear speck; cyclin K-CDK12 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDC2-related kinase 7; Cdc2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; cell division cycle 2-related protein kinase 7; cell division protein kinase 12; Crk7; CrkRS; cyclin-dependent kinase 12 isoform; Pksc; protein kinase for splicing component; similar to human CrkRS: CDC2-related protein kinase 7
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01086,157,188 - 86,222,535+NCBI
Rat Cytogenetic Map10q31 NCBI
RGSC Genome Assembly v5.01085,953,855 - 86,019,907+NCBI
RGSC Genome Assembly v3.41086,972,428 - 87,027,794+NCBI
Rat Celera Assembly1081,950,642 - 82,003,549+NCBI
Genome Assembly 3.11086,986,797 - 87,036,966+NCBI

Launch Genome Browser (GBrowse)     Launch JBrowse

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Cdk12
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 621111
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE