| 1,2-dichloroethene | decreases activity | EXP | | 6480464 | 1,2-dichloroethylene results in decreased activity of CYP2C6 protein; more ... | CTD | PMID:9671540 |
| 1,4-naphthoquinone | increases abundance | ISO | RGD:1322740 | 6480464 | CYP2C18 protein results in increased abundance of 1,4-naphthoquinone | CTD | PMID:16243959 |
| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of CYP2C6 mRNA | CTD | PMID:16940010 more ... |
| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of CYP2C6 mRNA | CTD | PMID:17108234 more ... |
| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:15953391 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1619904 | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of CYP2C50 mRNA | CTD | PMID:16214954 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CYP2C6V1 mRNA | CTD | PMID:21724226 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1322740 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CYP2C18 mRNA | CTD | PMID:16985168 |
| 2,6-di-tert-butyl-4-methylphenol | increases expression | EXP | | 6480464 | Butylated Hydroxytoluene results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:18539377 |
| 2-nitroanisole | increases oxidation | EXP | | 6480464 | CYP2C6 protein results in increased oxidation of 2-nitroanisole; more ... | CTD | PMID:21218109 |
| acenocoumarol | affects response to substance | ISO | RGD:1322740 | 6480464 | CYP2C18 gene polymorphism affects the susceptibility to Acenocoumarol | CTD | PMID:19578179 |
| aflatoxin B1 | affects expression | ISO | RGD:1322740 | 6480464 | Aflatoxin B1 affects the expression of CYP2C18 protein | CTD | PMID:20106945 |
| aflatoxin B1 | decreases expression | ISO | RGD:1322740 | 6480464 | Aflatoxin B1 results in decreased expression of CYP2C18 mRNA | CTD | PMID:22100608 |
| aflatoxin B1 | decreases expression | ISO | RGD:1619904 | 6480464 | Aflatoxin B1 results in decreased expression of CYP2C50 mRNA | CTD | PMID:19770486 |
| all-trans-retinoic acid | decreases expression | ISO | RGD:1322740 | 6480464 | Tretinoin results in decreased expression of CYP2C18 mRNA | CTD | PMID:16985168 |
| all-trans-retinoic acid | increases hydroxylation | EXP | | 6480464 | CYP2C6 protein results in increased hydroxylation of Tretinoin; more ... | CTD | PMID:14623888 |
| all-trans-retinoic acid | multiple interactions | EXP | | 6480464 | AHR protein promotes the reaction [CYP2C6 protein results in increased hydroxylation of Tretinoin]; more ... | CTD | PMID:14623888 |
| alpha-hexachlorocyclohexane | increases expression | EXP | | 6480464 | alpha-hexachlorocyclohexane results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:16940010 |
| alpha-hexachlorocyclohexane | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C6 protein; more ... | CTD | PMID:16246485 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CYP2C6 mRNA; more ... | CTD | PMID:16483693 |
| aristolochic acid | multiple interactions | EXP | | 6480464 | [CYP2C6 protein co-treated with CYB5A protein] results in increased abundance of aristolochic acid I metabolite; more ... | CTD | PMID:21362632 |
| Aroclor 1254 | increases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of CYP2C6 protein; more ... | CTD | PMID:8471063 |
| benzylideneacetone | increases oxidation | EXP | | 6480464 | CYP2C6 protein results in increased oxidation of benzylideneacetone; more ... | CTD | PMID:15863696 |
| chalcone | increases hydroxylation | EXP | | 6480464 | CYP2C6 protein results in increased hydroxylation of Chalcone; more ... | CTD | PMID:15863696 |
| chlorzoxazone | affects metabolic processing | EXP | | 6480464 | CYP2C6 protein affects the metabolism of Chlorzoxazone; more ... | CTD | PMID:15879494 |
| ciprofibrate | decreases expression | ISO | RGD:1619904 | 6480464 | ciprofibrate results in decreased expression of CYP2C50 mRNA | CTD | PMID:12771043 |
| cis-ketoconazole | multiple interactions | EXP | | 6480464 | Ketoconazole inhibits the reaction [CYP2C6 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; more ... | CTD | PMID:19858067 |
| cis-ketoconazole | decreases activity | EXP | | 6480464 | Ketoconazole results in decreased activity of CYP2C6 protein; more ... | CTD | PMID:12814958 PMID:15879494 |
| cis-ketoconazole | decreases activity | EXP | | 6480464 | Ketoconazole results in decreased activity of CYP2C6 protein | CTD | PMID:15879494 PMID:12814958 |
| clotrimazole | multiple interactions | EXP | | 6480464 | Clotrimazole inhibits the reaction [CYP2C6 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; more ... | CTD | PMID:19858067 |
| cyclophosphamide | increases activity | ISO | RGD:1322740 | 6480464 | CYP2C18 results in increased activity of Cyclophosphamide | CTD | PMID:9241661 |
| cyclophosphamide | increases metabolic processing | EXP | | 6480464 | CYP2C6 results in increased metabolism of Cyclophosphamide; more ... | CTD | PMID:20566340 |
| cyclophosphamide | increases response to substance | ISO | RGD:1322740 | 6480464 | CYP2C18 results in increased susceptibility to Cyclophosphamide | CTD | PMID:9766669 |
| cyclophosphamide | multiple interactions | ISO | RGD:1322740 | 6480464 | POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide] | CTD | PMID:9766669 |
| cyclosporin A | decreases expression | ISO | RGD:1322740 | 6480464 | Cyclosporine results in decreased expression of CYP2C18 mRNA | CTD | PMID:20106945 |
| cyclosporin A | decreases expression | ISO | RGD:1619904 | 6480464 | Cyclosporine results in decreased expression of CYP2C50 mRNA | CTD | PMID:19770486 |
| deoxycholic acid | decreases expression | EXP | | 6480464 | Deoxycholic Acid results in decreased expression of CYP2C6 protein; more ... | CTD | PMID:10453939 |
| deoxycholic acid | multiple interactions | EXP | | 6480464 | Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of CYP2C6 protein]; more ... | CTD | PMID:10453939 |
| diclofenac | increases hydroxylation | EXP | | 6480464 | CYP2C6 protein results in increased hydroxylation of Diclofenac; more ... | CTD | PMID:11911841 |
| dimethyl sulfoxide | multiple interactions | EXP | | 6480464 | Dimethyl Sulfoxide inhibits the reaction [CYP2C6 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; more ... | CTD | PMID:19858067 |
| ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:17920746 |
| fluoxetine | multiple interactions | EXP | | 6480464 | Fluoxetine inhibits the reaction [CYP2C6 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; more ... | CTD | PMID:19858067 |
| genistein | increases hydroxylation | EXP | | 6480464 | CYP2C6 protein results in increased hydroxylation of Genistein; more ... | CTD | PMID:15587933 |
| ifosfamide | increases activity | ISO | RGD:1322740 | 6480464 | CYP2C18 results in increased activity of Ifosfamide | CTD | PMID:9241661 |
| ifosfamide | increases metabolic processing | ISO | RGD:1322740 | 6480464 | CYP2C18 results in increased metabolism of Ifosfamide | CTD | PMID:15301741 |
| ifosfamide | multiple interactions | ISO | RGD:1322740 | 6480464 | POR promotes the reaction [CYP2C18 results in increased susceptibility to Ifosfamide] | CTD | PMID:9766669 |
| ifosfamide | increases response to substance | ISO | RGD:1322740 | 6480464 | CYP2C18 results in increased susceptibility to Ifosfamide | CTD | PMID:15301741 PMID:9766669 |
| indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of CYP2C6 mRNA; more ... | CTD | PMID:21396975 |
| indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP2C6V1 mRNA | CTD | PMID:22129741 |
| lamotrigine | increases glutathionylation | EXP | | 6480464 | CYP2C6 protein results in increased glutathionylation of lamotrigine; more ... | CTD | PMID:19961160 |
| lansoprazole | increases hydroxylation | ISO | RGD:1322740 | 6480464 | CYP2C18 protein results in increased hydroxylation of lansoprazole | CTD | PMID:7870052 |
| lansoprazole | increases expression | EXP | | 6480464 | lansoprazole results in increased expression of CYP2C6 protein; more ... | CTD | PMID:9152597 |
| lansoprazole | increases expression | EXP | | 6480464 | lansoprazole results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:14550749 |
| mangiferin | decreases activity | EXP | | 6480464 | mangiferin results in decreased activity of CYP2C6 protein; more ... | CTD | PMID:18053976 |
| methoxsalen | decreases activity | EXP | | 6480464 | Methoxsalen results in decreased activity of CYP2C6 protein | CTD | PMID:15879494 PMID:12814958 |
| methoxsalen | decreases activity | EXP | | 6480464 | Methoxsalen results in decreased activity of CYP2C6 protein; more ... | CTD | PMID:12814958 PMID:15879494 |
| methoxychlor | decreases methylation | ISO | RGD:1322740 | 6480464 | CYP2C18 protein results in decreased methylation of Methoxychlor | CTD | PMID:9733665 |
| mono(2-ethylhexyl) phthalate | increases metabolic processing | EXP | | 6480464 | CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate | CTD | PMID:22186153 |
| mono(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; more ... | CTD | PMID:22186153 |
| N-nitrosodiethylamine | decreases expression | ISO | RGD:1619904 | 6480464 | Diethylnitrosamine results in decreased expression of CYP2C50 mRNA | CTD | PMID:12771043 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP2C6V1 mRNA | CTD | PMID:22129741 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP2C6 protein; more ... | CTD | PMID:9744545 |
| N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of CYP2C6 mRNA; more ... | CTD | PMID:20360939 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C6 protein; more ... | CTD | PMID:16246485 |
| paracetamol | decreases expression | ISO | RGD:1322740 | 6480464 | Acetaminophen results in decreased expression of CYP2C18 mRNA | CTD | PMID:21420995 |
| paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of CYP2C6 mRNA; more ... | CTD | PMID:16328009 |
| perfluorooctane-1-sulfonic acid | affects expression | ISO | RGD:1619904 | 6480464 | perfluorooctane sulfonic acid affects the expression of CYP2C50 mRNA | CTD | PMID:19429403 |
| perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:21723365 |
| perfluorooctanoic acid | affects expression | ISO | RGD:1619904 | 6480464 | perfluorooctanoic acid affects the expression of CYP2C50 mRNA | CTD | PMID:18281256 PMID:19429403 |
| perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:21723365 |
| phenacetin | affects metabolic processing | EXP | | 6480464 | CYP2C6 protein affects the metabolism of Phenacetin; more ... | CTD | PMID:15231049 PMID:15879494 |
| phenacetin | affects metabolic processing | EXP | | 6480464 | CYP2C6 protein affects the metabolism of Phenacetin | CTD | PMID:15879494 PMID:15231049 |
| phenacetin | decreases ethylation | EXP | | 6480464 | CYP2C6 protein results in decreased ethylation of Phenacetin; more ... | CTD | PMID:11911841 |
| phenobarbital | increases expression | ISO | RGD:1619904 | 6480464 | Phenobarbital results in increased expression of CYP2C50 mRNA | CTD | PMID:19270015 |
| phenobarbital | affects expression | ISO | RGD:1619904 | 6480464 | Phenobarbital affects the expression of CYP2C50 mRNA | CTD | PMID:23091169 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of CYP2C6 protein | CTD | PMID:9152597 PMID:10506011 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of CYP2C6 mRNA | CTD | PMID:19162173 PMID:16510358 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of CYP2C6 protein; more ... | CTD | PMID:10506011 PMID:9152597 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:16510358 PMID:19162173 |
| phenobarbital | increases activity | EXP | | 6480464 | Phenobarbital results in increased activity of CYP2C6 protein; more ... | CTD | PMID:16781091 |
| phenobarbital | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP2C6 protein; more ... | CTD | PMID:9744545 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of CYP2C6 protein; more ... | CTD | PMID:15713442 |
| pirinixic acid | multiple interactions | ISO | RGD:1619904 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in decreased expression of CYP2C50 mRNA] | CTD | PMID:18467677 |
| pirinixic acid | decreases expression | ISO | RGD:1619904 | 6480464 | pirinixic acid results in decreased expression of CYP2C50 mRNA | CTD | PMID:18467677 PMID:20936131 |
| pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of CYP2C6 mRNA; more ... | CTD | PMID:16940010 |
| pirinixic acid | decreases expression | ISO | RGD:1619904 | 6480464 | pirinixic acid results in decreased expression of CYP2C50 mRNA | CTD | PMID:18467677 |
| progesterone | decreases expression | ISO | RGD:1322740 | 6480464 | Progesterone results in decreased expression of CYP2C18 mRNA | CTD | PMID:18070364 |
| propiconazole | increases expression | ISO | RGD:1619904 | 6480464 | propiconazole results in increased expression of CYP2C50 mRNA | CTD | PMID:21278054 PMID:22334560 |
| quinidine | decreases activity | EXP | | 6480464 | Quinidine results in decreased activity of CYP2C6 protein; more ... | CTD | PMID:12814958 |
| quinine | decreases activity | EXP | | 6480464 | Quinine results in decreased activity of CYP2C6 protein; more ... | CTD | PMID:12814958 PMID:15879494 |
| quinine | decreases activity | EXP | | 6480464 | Quinine results in decreased activity of CYP2C6 protein | CTD | PMID:15879494 PMID:12814958 |
| tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of CYP2C6 protein; more ... | CTD | PMID:17606319 |
| tolbutamide | increases metabolic processing | ISO | RGD:1322740 | 6480464 | CYP2C18 results in increased metabolism of Tolbutamide | CTD | PMID:15301741 |
| toluene | increases oxidation | EXP | | 6480464 | CYP2C6 protein results in increased oxidation of Toluene; more ... | CTD | PMID:1994898 |
| trans-1,2-dichloroethene | decreases activity | EXP | | 6480464 | 1,2-dichloroethylene results in decreased activity of CYP2C6 protein; more ... | CTD | PMID:9671540 |
| ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of CYP2C6 protein]; more ... | CTD | PMID:10453939 |
| valproic acid | affects expression | ISO | RGD:1619904 | 6480464 | Valproic Acid affects the expression of CYP2C50 mRNA | CTD | PMID:17963808 |