Gene: Mthfr (methylenetetrahydrofolate reductase (NAD(P)H))  Rattus norvegicus

Symbol: Mthfr
Name: methylenetetrahydrofolate reductase (NAD(P)H)
Description: ENCODES a protein that exhibits flavin adenine dinucleotide binding; methylenetetrahydrofolate reductase (NADPH) activity; NADP binding; INVOLVED IN homocysteine metabolic process; response to amino acid stimulus; response to drug; PARTICIPATES IN altered folate cycle metabolic pathway; altered folate mediated one-carbon metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; Hyperthyroidism; Hypothyroidism; FOUND IN cytosol; neuron projection; INTERACTS WITH ammonium chloride; indole-3-methanol; N-nitrosodiethylamine
Type: protein-coding
RefSeq Status: MODEL
Also known as: 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); 5,10-methylenetetrahydrofolate reductase (nadph) (predicted); 5,10-methylenetetrahydrofolate reductase (NADPH) (predicted); LOC362657; methylenetetrahydrofolate reductase; mthfr_predicted; Mthfr_predicted
Orthologs: Homo sapiens : MTHFR (methylenetetrahydrofolate reductase (NAD(P)H))  HGNC
Mus musculus : Mthfr (5,10-methylenetetrahydrofolate reductase)  MGI
Allele / Splice: Mthfrem1Mcwi  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map5q36 NCBI
RGSC Genome Assembly v5.05168,504,563 - 168,518,702+NCBI
RGSC Genome Assembly v3.45165,112,850 - 165,126,885+NCBI
Rat Celera Assembly5156,749,043 - 156,763,094+NCBI
Genome Assembly 3.15165,123,406 - 165,137,073+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mthfr
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1309952
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2013-04-30
Status: ACTIVE