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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking Mthfr and spina bifida in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Botto LD and Yang Q, Am J Epidemiol. 2000 May 1;151(9):862-77.
  • The annotation has been inferred from sequence orthology with MTHFR (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Botto LD and Yang Q, Am J Epidemiol. 2000 May 1;151(9):862-77.
  • 41 RGD objects have been annotated to spina bifida  (DOID:0080016)
  • 173 papers in RGD have been used to annotate Mthfr
  • Qualifier: susceptibility
  • Curation Notes: DNA:transition:cds:g.677C>T (human)


    • An association has been curated linking Mthfr and spina bifida in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Volcik KA, etal., Birth Defects Res A Clin Mol Teratol. 2003 Mar;67(3):154-7.
  • The annotation has been inferred from sequence orthology with MTHFR (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Volcik KA, etal., Birth Defects Res A Clin Mol Teratol. 2003 Mar;67(3):154-7.
  • 41 RGD objects have been annotated to spina bifida  (DOID:0080016)
  • 173 papers in RGD have been used to annotate Mthfr
  • Qualifier: severity
  • Curation Notes: DNA:polymorphism: :677C>T(human)


    • An association has been curated linking Mthfr and spina bifida in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Nitsche F, etal., Rev Med Chil. 2003 Dec;131(12):1399-404.
  • The annotation has been inferred from sequence orthology with MTHFR (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Nitsche F, etal., Rev Med Chil. 2003 Dec;131(12):1399-404.
  • 41 RGD objects have been annotated to spina bifida  (DOID:0080016)
  • 173 papers in RGD have been used to annotate Mthfr
  • Qualifier: no_association
  • Curation Notes: DNA:polymorphism: :677C>T(human)


    • An association has been curated linking Mthfr and spina bifida in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with MTHFR (Homo sapiens) [(EXP) inferred from experiment]
  • 41 RGD objects have been annotated to spina bifida  (DOID:0080016)
  • 173 papers in RGD have been used to annotate Mthfr
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:27713094


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