Gene: Mapk8 (mitogen-activated protein kinase 8) Rattus norvegicus
Symbol: Mapk8
Name: mitogen-activated protein kinase 8
Description: ENCODES a protein that exhibits JUN kinase activity; kinesin binding; enzyme binding (ortholog); INVOLVED IN cellular response to beta-amyloid; cellular response to interleukin-1; glial cell apoptotic process; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; inflammatory response pathway; Rho/Rac/Cdc42 mediated signaling pathway; ASSOCIATED WITH Anti-Glomerular Basement Membrane Disease; Brain Ischemia; Hypertension; FOUND IN axon; cytoplasm; dendrite cytoplasm; INTERACTS WITH (-)-anisomycin; (R)-lipoic acid; (R)-noradrenaline
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-Jun N-terminal kinase 1; c-jun NH2-terminal kinase; JNK; MAP kinase 8; MAPK 8; p54 gamma; SAPK gamma; stress-activated protein kinase JNK1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0169,620,854 - 9,709,342 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01611,579,503 - 11,662,858 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4168,925,133 - 9,004,897 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1168,925,181 - 9,004,945 (-)NCBI
Celera166,485,592 - 6,568,388 (+)NCBI
Cytogenetic Map16p16NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mapk8
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621506
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE