Gene: Mapk8 (mitogen-activated protein kinase 8) Rattus norvegicus
Symbol: Mapk8
Name: mitogen-activated protein kinase 8
Description: ENCODES a protein that exhibits JUN kinase activity; kinesin binding; enzyme binding (ortholog); INVOLVED IN cellular response to beta-amyloid; cellular response to interleukin-1; glial cell apoptotic process; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; inflammatory response pathway; Rho/Rac/Cdc42 mediated signaling pathway; ASSOCIATED WITH Anti-Glomerular Basement Membrane Disease; Brain Ischemia; Hypertension; FOUND IN axon; cytoplasm; dendrite cytoplasm; INTERACTS WITH (-)-anisomycin; (R)-lipoic acid; (R)-noradrenaline
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-Jun N-terminal kinase 1; c-jun NH2-terminal kinase; JNK; MAP kinase 8; MAPK 8; p54 gamma; SAPK gamma; stress-activated protein kinase JNK1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0169,620,854 - 9,709,342 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01611,579,503 - 11,662,858 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4168,925,133 - 9,004,897 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1168,925,181 - 9,004,945 (-)NCBI
Celera166,485,592 - 6,568,388 (+)NCBI
Cytogenetic Map16p16NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mapk8
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 621506
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-10-11
Status: ACTIVE