Arid2 (AT-rich interaction domain 2) - Rat Genome Database

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Gene: Arid2 (AT-rich interaction domain 2) Rattus norvegicus
Analyze
Symbol: Arid2
Name: AT-rich interaction domain 2
RGD ID: 1311105
Description: Predicted to enable DNA binding activity. Predicted to be involved in several processes, including negative regulation of cell migration; nucleosome disassembly; and positive regulation of double-strand break repair via homologous recombination. Predicted to act upstream of or within embryonic organ development; heart development; and homeostatic process. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6; colorectal cancer; and hepatocellular carcinoma. Orthologous to human ARID2 (AT-rich interaction domain 2); PARTICIPATES IN SWI/SNF family mediated chromatin remodeling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AT rich interactive domain 2 (Arid-rfx like); AT-rich interactive domain-containing protein 2; LOC366980
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87129,326,371 - 129,443,813 (+)NCBIGRCr8
mRatBN7.27127,447,192 - 127,565,987 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7127,447,278 - 127,563,512 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.07137,680,564 - 137,798,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7137,680,530 - 137,795,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07137,312,585 - 137,430,353 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47134,959,992 - 135,077,477 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17135,036,399 - 135,153,718 (+)NCBI
Celera7123,951,414 - 124,071,020 (+)NCBICelera
Cytogenetic Map7q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetazolamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroprene  (EXP)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
dexamethasone  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
Lasiocarpine  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
monocrotaline  (ISO)
oxaliplatin  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
riddelliine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sunitinib  (ISO)
theophylline  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer. Bala P, etal., Oncogene. 2021 Jan;40(4):863-874. doi: 10.1038/s41388-020-01537-z. Epub 2020 Dec 1.
2. Chromatin remodeling gene ARID2 targets cyclin D1 and cyclin E1 to suppress hepatoma cell progression. Duan Y, etal., Oncotarget. 2016 Jul 19;7(29):45863-45875. doi: 10.18632/oncotarget.10244.
3. HBx protein-mediated ATOH1 downregulation suppresses ARID2 expression and promotes hepatocellular carcinoma. Gao Q, etal., Cancer Sci. 2017 Jul;108(7):1328-1337. doi: 10.1111/cas.13277. Epub 2017 Jun 14.
4. ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Hargreaves DC and Crabtree GR, Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Epub 2011 Mar 1.
5. Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis. Jiang H, etal., Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4770-4780. doi: 10.1073/pnas.1914937117. Epub 2020 Feb 18.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. The spectrum of SWI/SNF mutations, ubiquitous in human cancers. Shain AH and Pollack JR, PLoS One. 2013;8(1):e55119. doi: 10.1371/journal.pone.0055119. Epub 2013 Jan 23.
11. MiR-155-5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2. Wu M, etal., Biomed Pharmacother. 2020 Feb;122:109696. doi: 10.1016/j.biopha.2019.109696. Epub 2019 Dec 30.
12. AT-rich interactive domain 2, p110α, p53, and β-catenin protein expression in hepatocellular carcinoma and clinicopathologic implications. You J, etal., Hum Pathol. 2015 Apr;46(4):583-92. doi: 10.1016/j.humpath.2015.01.001. Epub 2015 Jan 14.
Additional References at PubMed
PMID:8895581   PMID:21873635   PMID:24335282   PMID:25299188   PMID:26169693   PMID:28381560  


Genomics

Comparative Map Data
Arid2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87129,326,371 - 129,443,813 (+)NCBIGRCr8
mRatBN7.27127,447,192 - 127,565,987 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7127,447,278 - 127,563,512 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.07137,680,564 - 137,798,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7137,680,530 - 137,795,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07137,312,585 - 137,430,353 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47134,959,992 - 135,077,477 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17135,036,399 - 135,153,718 (+)NCBI
Celera7123,951,414 - 124,071,020 (+)NCBICelera
Cytogenetic Map7q35NCBI
ARID2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381245,729,706 - 45,908,037 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1245,729,706 - 45,908,040 (+)EnsemblGRCh38hg38GRCh38
GRCh371246,123,489 - 46,301,820 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361244,409,887 - 44,588,086 (+)NCBINCBI36Build 36hg18NCBI36
Celera1244,920,557 - 45,099,159 (+)NCBICelera
Cytogenetic Map12q12NCBI
HuRef1243,152,842 - 43,332,608 (+)NCBIHuRef
CHM1_11246,088,579 - 46,266,707 (+)NCBICHM1_1
T2T-CHM13v2.01245,688,334 - 45,867,621 (+)NCBIT2T-CHM13v2.0
Arid2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391596,185,403 - 96,303,344 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1596,185,399 - 96,302,873 (+)EnsemblGRCm39 Ensembl
GRCm381596,287,522 - 96,405,463 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1596,287,518 - 96,404,992 (+)EnsemblGRCm38mm10GRCm38
MGSCv371596,117,953 - 96,235,894 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361596,197,538 - 96,230,331 (+)NCBIMGSCv36mm8
Celera1598,438,688 - 98,556,626 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1552.37NCBI
Arid2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555004,998,555 - 5,175,776 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555004,998,555 - 5,177,180 (+)NCBIChiLan1.0ChiLan1.0
ARID2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21048,261,225 - 48,443,133 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11248,257,983 - 48,439,555 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01242,823,236 - 43,004,465 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11243,692,717 - 43,871,652 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1243,692,914 - 43,871,564 (-)Ensemblpanpan1.1panPan2
ARID2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,411,092 - 8,579,735 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,412,377 - 8,579,882 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2737,733,310 - 37,902,134 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0278,605,853 - 8,775,028 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl278,605,848 - 8,775,217 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,413,511 - 8,582,264 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0278,452,603 - 8,621,753 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02737,971,938 - 38,141,085 (+)NCBIUU_Cfam_GSD_1.0
Arid2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494568,966,896 - 69,144,185 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365124,020,966 - 4,196,459 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365124,020,303 - 4,199,390 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARID2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl576,636,967 - 76,797,043 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1576,637,385 - 76,800,155 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2579,655,352 - 79,725,991 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARID2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11141,933,650 - 42,117,495 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1142,028,083 - 42,118,892 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037204,323,064 - 204,512,703 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arid2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248166,332,612 - 6,521,535 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248166,329,888 - 6,521,535 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arid2
549 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:222
Count of miRNA genes:160
Interacting mature miRNAs:175
Transcripts:ENSRNOT00000006970, ENSRNOT00000072800
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
D7Got154  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27127,455,195 - 127,455,343 (+)MAPPERmRatBN7.2
Rnor_6.07137,687,927 - 137,688,074NCBIRnor6.0
Rnor_5.07137,319,951 - 137,320,098UniSTSRnor5.0
RGSC_v3.47134,969,369 - 134,969,516RGDRGSC3.4
RGSC_v3.47134,969,369 - 134,969,516UniSTSRGSC3.4
RGSC_v3.17135,045,806 - 135,045,953RGD
Celera7123,961,191 - 123,961,343UniSTS
RH 3.4 Map71092.0RGD
RH 3.4 Map71092.0UniSTS
RH 2.0 Map7773.9RGD
Cytogenetic Map7q35UniSTS
RH143678  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27127,445,042 - 127,445,162 (+)MAPPERmRatBN7.2
Rnor_6.07137,678,394 - 137,678,513NCBIRnor6.0
Rnor_5.07137,310,390 - 137,310,509UniSTSRnor5.0
RGSC_v3.47134,959,850 - 134,959,969UniSTSRGSC3.4
Celera7123,951,272 - 123,951,391UniSTS
RH 3.4 Map71098.9UniSTS
Cytogenetic Map7q35UniSTS
BF398770  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27127,460,365 - 127,460,572 (+)MAPPERmRatBN7.2
Rnor_6.07137,693,095 - 137,693,301NCBIRnor6.0
Rnor_5.07137,325,119 - 137,325,325UniSTSRnor5.0
RGSC_v3.47134,974,537 - 134,974,743UniSTSRGSC3.4
Celera7123,966,364 - 123,966,570UniSTS
RH 3.4 Map2180.4UniSTS
Cytogenetic Map7q35UniSTS
ARID2_3730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27127,563,909 - 127,564,650 (+)MAPPERmRatBN7.2
Rnor_6.07137,796,251 - 137,796,991NCBIRnor6.0
Rnor_5.07137,428,275 - 137,429,015UniSTSRnor5.0
RGSC_v3.47135,078,075 - 135,078,815UniSTSRGSC3.4
Celera7124,068,942 - 124,069,682UniSTS
Cytogenetic Map7q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 28 33 17 19 17 2 2 74 30 41 11 2
Low 2 15 24 24 24 6 9 5 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006970   ⟹   ENSRNOP00000006970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7127,447,278 - 127,563,512 (+)Ensembl
Rnor_6.0 Ensembl7137,680,530 - 137,795,655 (+)Ensembl
RefSeq Acc Id: XM_063264356   ⟹   XP_063120426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87129,343,693 - 129,443,813 (+)NCBI
RefSeq Acc Id: XM_345867   ⟹   XP_345868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87129,326,371 - 129,443,813 (+)NCBI
mRatBN7.27127,447,192 - 127,565,987 (+)NCBI
Rnor_6.07137,680,564 - 137,798,329 (+)NCBI
Rnor_5.07137,312,585 - 137,430,353 (+)NCBI
RGSC_v3.47134,959,992 - 135,077,477 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_063120426 (Get FASTA)   NCBI Sequence Viewer  
  XP_345868 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006970
  ENSRNOP00000006970.6
Reference Protein Sequences
RefSeq Acc Id: XP_345868   ⟸   XM_345867
- Peptide Label: isoform X1
- UniProtKB: D3ZJU0 (UniProtKB/TrEMBL),   A6KC19 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006970   ⟸   ENSRNOT00000006970
RefSeq Acc Id: XP_063120426   ⟸   XM_063264356
- Peptide Label: isoform X2
Protein Domains
ARID   RFX-type winged-helix

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJU0-F1-model_v2 AlphaFold D3ZJU0 1-1826 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695617
Promoter ID:EPDNEW_R6132
Type:initiation region
Name:Arid2_1
Description:AT-rich interaction domain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07137,680,606 - 137,680,666EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311105 AgrOrtholog
BioCyc Gene G2FUF-32260 BioCyc
Ensembl Genes ENSRNOG00000004831 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006970.9 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.60 UniProtKB/TrEMBL
InterPro ARID/BRIGHT_DNA-bd UniProtKB/TrEMBL
  ARID_dom_sf UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DNA-bd_RFX UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report rno:366980 UniProtKB/TrEMBL
NCBI Gene 366980 ENTREZGENE
PANTHER AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam ARID UniProtKB/TrEMBL
  RFX_DNA_binding UniProtKB/TrEMBL
PhenoGen Arid2 PhenoGen
PROSITE ARID UniProtKB/TrEMBL
  RFX_DBD UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004831 RatGTEx
SMART ARID UniProtKB/TrEMBL
  BRIGHT UniProtKB/TrEMBL
Superfamily-SCOP ARID UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A6KC19 ENTREZGENE, UniProtKB/TrEMBL
  D3ZJU0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Arid2  AT-rich interaction domain 2  Arid2  AT rich interactive domain 2 (Arid-rfx like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Arid2  AT rich interactive domain 2 (Arid-rfx like)   Arid2_predicted  AT rich interactive domain 2 (Arid-rfx like) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Arid2_predicted  AT rich interactive domain 2 (Arid-rfx like) (predicted)      Symbol and Name status set to approved 70820 APPROVED