Gene: Aco2 (aconitase 2) Rattus norvegicus
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Symbol: Aco2
Name: aconitase 2
Description: ENCODES a protein that exhibits 3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; aconitate hydratase activity; INVOLVED IN citrate metabolic process; isocitrate metabolic process; liver development; PARTICIPATES IN citric acid cycle pathway; fumaric aciduria disease pathway; mitochondrial complex II deficiency pathway; ASSOCIATED WITH Carcinoma, Hepatocellular (ortholog); Developmental Disabilities (ortholog); Genetic Diseases, Inborn (ortholog); FOUND IN mitochondrion; myelin sheath (ortholog); INTERACTS WITH (R)-adrenaline; 1,3-dinitrobenzene; 2,2,2-tetramine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aconitase 2, mitochondrial; aconitate hydratase, mitochondrial; citrate hydro-lyase; mitochondrial aconitase (nuclear aco2 gene)
Orthologs:
Homo sapiens (human) : ACO2 (aconitase 2)  HGNC  AGR
Mus musculus (house mouse) : Aco2 (aconitase 2, mitochondrial)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Aco2 (aconitase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACO2 (aconitase 2)
Canis lupus familiaris (dog) : ACO2 (aconitase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aco2 (aconitase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07123,102,493 - 123,145,608 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07123,077,888 - 123,121,003 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,223,788 - 120,266,944 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,258,017 - 120,301,166 (+)NCBI
Celera7109,704,354 - 109,747,462 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aco2
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621360
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE