Gene: Mpl (MPL proto-oncogene, thrombopoietin receptor) Rattus norvegicus
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Symbol: Mpl
Name: MPL proto-oncogene, thrombopoietin receptor
Description: ENCODES a protein that exhibits thrombopoietin receptor activity (ortholog); INVOLVED IN basophil homeostasis; cellular response to hypoxia; eosinophil homeostasis; PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH myelofibrosis; Primary Myelofibrosis; Thrombocytopenia; FOUND IN cell surface; neuron projection; neuronal cell body; INTERACTS WITH bisphenol A; 4,4'-diaminodiphenylmethane (ortholog); 5-aza-2'-deoxycytidine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC366455; myeloproliferative leukemia virus oncogene; thrombopoietin receptor
Orthologs:
Homo sapiens (human) : MPL (MPL proto-oncogene, thrombopoietin receptor)  HGNC  AGR
Mus musculus (house mouse) : Mpl (myeloproliferative leukemia virus oncogene)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Mpl (MPL proto-oncogene, thrombopoietin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : MPL (MPL proto-oncogene, thrombopoietin receptor)
Canis lupus familiaris (dog) : MPL (MPL proto-oncogene, thrombopoietin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpl (MPL proto-oncogene, thrombopoietin receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05137,268,412 - 137,282,032 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05141,057,876 - 141,070,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45138,921,281 - 138,931,990 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15138,922,155 - 138,937,216 (-)NCBI
Celera5130,519,369 - 130,532,972 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mpl
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311069
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE