Gene: Mpl (MPL proto-oncogene, thrombopoietin receptor) Rattus norvegicus
Symbol: Mpl
Name: MPL proto-oncogene, thrombopoietin receptor
Description: ENCODES a protein that exhibits cytokine receptor activity (inferred); INVOLVED IN homeostasis of number of cells (ortholog); regulation of chemokine production (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH Congenital amegakaryocytic thrombocytopenia (ortholog); Primary Myelofibrosis (ortholog); Thrombocytopenia (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 4,4'-diaminodiphenylmethane (ortholog); 5-aza-2'-deoxycytidine (ortholog); benzene (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC366455; myeloproliferative leukemia virus oncogene; thrombopoietin receptor
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map5q36 NCBI
RGSC Genome Assembly v5.05141,057,876 - 141,070,834-NCBI
RGSC Genome Assembly v3.45138,921,281 - 138,931,990-NCBI
Rat Celera Assembly5130,519,369 - 130,532,310-NCBI
Genome Assembly 3.15138,922,155 - 138,937,216-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mpl
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1311069
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2014-06-26
Status: ACTIVE