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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Liver Neoplasms
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Accession:DOID:9007188 term browser browse the term
Synonyms:exact_synonym: NEOPLASM OF THE LIVER;   hepatic neoplasm;   hepatic neoplasms;   liver neoplasm;   neoplasm of liver
 primary_id: MESH:D008113
 xref: EFO:1001513

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Liver Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734 		JBrowse link
G ABTB3 ankyrin repeat and BTB domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr11:102,535,469...102,882,227
Ensembl chr11:102,800,591...102,882,388 		JBrowse link
G ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr29:18,484,341...18,842,210
Ensembl chr29:18,481,449...18,841,568 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19996281 PMID:30346592 NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478 		JBrowse link
G ANXA2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr26:23,100,000...23,147,687
Ensembl chr26:23,099,992...23,145,457 		JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr14:37,297,960...37,384,187
Ensembl chr14:37,297,652...37,344,884 		JBrowse link
G ANXA7 annexin A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr 9:57,863,482...57,900,972
Ensembl chr 9:57,863,546...57,900,324 		JBrowse link
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Neoplasm of the liver ClinVar PMID:16569251 PMID:18199528 PMID:21859464 PMID:22703879 PMID:23159591 More... NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067 		JBrowse link
G APCS amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:20195826 NCBI chr20:4,360,955...4,363,810
Ensembl chr20:4,358,654...4,362,095 		JBrowse link
G ASH1L ASH1 like histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064257 NCBI chr20:8,290,606...8,499,991
Ensembl chr20:8,322,504...8,500,129 		JBrowse link
G ASIP agouti signaling protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:15175105 NCBI chr 2:38,479,328...38,568,756 JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr21:51,244,514...51,264,694
Ensembl chr21:51,247,742...51,265,241 		JBrowse link
G ATP7B ATPase copper transporting beta onset ISO CTD Direct Evidence: marker/mechanism
compared to LEC/Tj;		 CTD
RGD		 PMID:11509115 RGD:1302456 NCBI chr 3:29,817,712...29,899,302
Ensembl chr 3:29,816,860...29,899,077 		JBrowse link
G BAP1 BRCA1 associated deubiquitinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17514646 NCBI chr21:109,495,525...109,690,261 JBrowse link
G CCDC134 coiled-coil domain containing 134 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr19:24,332,293...24,358,056
Ensembl chr19:24,332,316...24,357,583 		JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064257 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CCNH cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 4:81,373,812...81,392,454
Ensembl chr 4:81,373,994...81,392,326 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr15:77,435,195...77,439,164
Ensembl chr15:77,437,265...77,438,347 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16391232 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G CGREF1 cell growth regulator with EF-hand domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr14:80,500,056...80,516,893
Ensembl chr14:80,513,701...80,516,698 		JBrowse link
G CIDEA cell death inducing DFFA like effector a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 PMID:28108177 NCBI chr18:70,836,188...70,853,917 JBrowse link
G CLSTN2 calsyntenin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr15:49,996,144...50,622,454
Ensembl chr15:49,999,908...50,151,120 		JBrowse link
G CPT1B carnitine palmitoyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr19:33,044,272...33,055,197
Ensembl chr19:33,043,916...33,054,247 		JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr26:4,987,927...4,996,431
Ensembl chr26:4,987,882...4,996,343 		JBrowse link
G CSF2 colony stimulating factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:17326190 NCBI chr23:34,906,987...34,911,252
Ensembl chr23:34,908,911...34,911,140 		JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:9018096 NCBI chr16:66,162,814...66,166,192
Ensembl chr16:66,163,681...66,165,172 		JBrowse link
G CTNNB1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10467420 PMID:21047994 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr 7:22,327,041...22,329,405
Ensembl chr 7:22,569,355...22,569,900
Ensembl chr 7:22,569,355...22,569,900 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17093202 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G DACT2 dishevelled binding antagonist of beta catenin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr13:96,141,847...96,152,677 JBrowse link
G DCD dermcidin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20195826 NCBI chr11:50,760,466...50,765,369 JBrowse link
G DDX54 DEAD-box helicase 54 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr11:108,407,623...108,437,188
Ensembl chr11:108,404,719...108,437,168 		JBrowse link
G DICER1 dicer 1, ribonuclease III ISO CTD Direct Evidence: marker/mechanism CTD PMID:24478143 NCBI chr24:72,915,550...72,986,658
Ensembl chr24:72,915,499...72,963,006 		JBrowse link
G DPP10 dipeptidyl peptidase like 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr10:14,434,244...15,822,419 JBrowse link
G EFNB2 ephrin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 3:84,904,421...84,949,292
Ensembl chr 3:84,904,435...84,949,465 		JBrowse link
G ESM1 endothelial cell specific molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr 4:51,227,908...51,269,280
Ensembl chr 4:51,227,916...51,235,972 		JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16712894 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G EXOSC2 exosome component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr12:7,441,812...7,452,979
Ensembl chr12:7,442,791...7,452,964 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12112319 NCBI chr22:21,006,010...22,474,056 JBrowse link
G FLCN folliculin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr16:16,245,840...16,271,465
Ensembl chr16:16,245,715...16,267,698 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:26411935 NCBI chr 6:38,916,039...38,924,129 JBrowse link
G FST follistatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203361 NCBI chr 4:49,773,646...49,780,343
Ensembl chr 4:49,773,980...49,780,333 		JBrowse link
G GADL1 glutamate decarboxylase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr15:75,237,681...75,407,007
Ensembl chr15:75,237,675...75,405,706 		JBrowse link
G GJB1 gap junction protein beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2559087 NCBI chr  X:61,013,991...61,019,222
Ensembl chr  X:61,017,716...61,018,567 		JBrowse link
G GNMT glycine N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21137059 NCBI chr17:29,196,142...29,199,728
Ensembl chr17:29,196,321...29,198,947 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:30641053 NCBI chr28:20,491,874...20,497,966
Ensembl chr28:20,492,188...20,493,315 		JBrowse link
G GPX1 glutathione peroxidase 1 treatment ISO RGD PMID:26147624 RGD:152995453 NCBI chr22:10,754,976...10,756,617 JBrowse link
G GPX2 glutathione peroxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr24:42,151,205...42,155,335 JBrowse link
G GPX3 glutathione peroxidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20195826 NCBI chr23:53,576,950...53,585,321 JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr13:71,855,960...72,545,376
Ensembl chr13:71,855,794...72,325,857 		JBrowse link
G HCFC1 host cell factor C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19255062 NCBI chr  X:128,371,518...128,395,920
Ensembl chr  X:128,371,517...128,394,861 		JBrowse link
G HEBP2 heme binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr13:34,985,834...34,995,037
Ensembl chr13:34,986,129...34,994,809 		JBrowse link
G HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 7:36,945,452...37,068,574
Ensembl chr 7:36,958,239...37,066,994 		JBrowse link
G HGF hepatocyte growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:8807143 NCBI chr21:67,118,785...67,193,506
Ensembl chr21:67,120,722...67,193,504 		JBrowse link
G HIGD2A HIG1 hypoxia inducible domain family member 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr23:78,392,364...78,393,407 JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17002867 NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10874023 PMID:12082015 PMID:12127263 PMID:16410370 PMID:17514646 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G HSDL2 hydroxysteroid dehydrogenase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr12:27,051,287...27,132,884
Ensembl chr12:26,999,960...27,131,914 		JBrowse link
G IFT88 intraflagellar transport 88 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9362446 NCBI chr 3:435,649...546,661
Ensembl chr 3:436,207...546,583 		JBrowse link
G IGF2 insulin like growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12127304 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G IL12A interleukin 12A ISO CTD Direct Evidence: therapeutic CTD PMID:17326190 NCBI chr15:30,887,048...30,896,577
Ensembl chr15:30,887,897...30,894,550 		JBrowse link
G IL12B interleukin 12B ISO CTD Direct Evidence: therapeutic CTD PMID:17326190 NCBI chr23:61,714,293...61,731,835 JBrowse link
G IL2 interleukin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:18298334 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969 		JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 NCBI chr22:14,159,702...14,174,627
Ensembl chr22:14,160,680...14,174,641 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:12127263 PMID:24183702 NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10629081 PMID:12211074 NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G KRT18 keratin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19409407 PMID:19796649 NCBI chr11:49,073,733...49,081,706 JBrowse link
G KRT8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19409407 PMID:19796649 NCBI chr11:49,027,879...49,051,753 JBrowse link
G LARGE1 LARGE xylosyl- and glucuronyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr19:16,080,482...16,704,968
Ensembl chr19:16,080,430...16,549,495 		JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21214675 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B exacerbates ISO B6 strain RGD PMID:24838184 RGD:153298928 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LTF lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:12079509 NCBI chr22:7,867,332...7,896,403
Ensembl chr22:7,867,286...7,894,521 		JBrowse link
G MACIR macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr23:6,695,131...6,714,925
Ensembl chr23:6,712,171...6,712,791 		JBrowse link
G MACROD2 mono-ADP ribosylhydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064257 NCBI chr 2:42,891,656...44,973,129 JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17468757 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8807143 PMID:11532874 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G MYO5B myosin VB ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr18:30,759,345...31,143,139
Ensembl chr18:30,759,764...31,143,474 		JBrowse link
G NAT2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19666988 NCBI chr 8:16,451,144...16,494,961
Ensembl chr 8:16,493,749...16,494,621 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064257 NCBI chr16:15,442,315...15,629,411
Ensembl chr16:15,462,640...15,628,512 		JBrowse link
G NDRG1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341671 NCBI chr 8:127,668,012...127,727,918
Ensembl chr 8:127,667,981...127,719,011 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:20722399 PMID:35523338 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
G NOP16 NOP16 nucleolar protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr23:78,387,634...78,392,405
Ensembl chr23:78,387,877...78,392,238 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23178280 PMID:24091600 PMID:24189133 PMID:29142166 PMID:30556042 NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 PMID:19482888 PMID:22293087 PMID:24449422 PMID:28218408 NCBI chr20:2,724,843...2,752,999
Ensembl chr20:2,744,908...2,756,658 		JBrowse link
G NUDCD3 NudC domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr21:14,177,167...14,283,419
Ensembl chr21:14,177,173...14,284,469 		JBrowse link
G NUDT7 nudix hydrolase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr 5:63,212,163...63,231,465
Ensembl chr 5:63,212,226...63,231,650 		JBrowse link
G OAT ornithine aminotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr 9:117,060,819...117,083,160
Ensembl chr 9:117,060,393...117,083,126 		JBrowse link
G PDRG1 p53 and DNA damage regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 2:36,334,730...36,342,685
Ensembl chr 2:36,331,198...36,342,179 		JBrowse link
G PHGDH phosphoglycerate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr20:14,045,395...14,075,935
Ensembl chr20:14,045,346...14,076,177 		JBrowse link
G PLS1 plastin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 NCBI chr15:47,919,807...48,031,158
Ensembl chr15:47,919,823...48,003,805 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20143881 PMID:29134746
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:20143881 NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418 		JBrowse link
G PRICKLE2 prickle planar cell polarity protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr22:25,128,160...25,481,385
Ensembl chr22:25,133,352...25,303,131 		JBrowse link
G PRKCE protein kinase C epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343 		JBrowse link
G PSMA4 proteasome 20S subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20195826 NCBI chr26:4,793,046...4,802,098
Ensembl chr26:4,793,307...4,801,886 		JBrowse link
G PTER phosphotriesterase related ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr 9:16,382,479...16,539,382
Ensembl chr 9:16,429,776...16,457,737 		JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 PMID:20163174 NCBI chr11:15,225,375...15,494,559
Ensembl chr11:15,392,926...15,495,807 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19499222 NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020 		JBrowse link
G RTP3 receptor transporter protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17693185 NCBI chr22:7,925,733...7,930,132
Ensembl chr22:7,926,804...7,931,187 		JBrowse link
G SCD stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12419843 NCBI chr 9:93,380,812...93,398,860
Ensembl chr 9:93,380,914...93,398,912 		JBrowse link
G SIX3 SIX homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr14:62,278,124...62,292,942
Ensembl chr14:62,278,461...62,281,127 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr11:47,190,138...47,238,543
Ensembl chr11:47,197,168...47,235,130 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26943884 NCBI chr20:89,974,567...90,007,977
Ensembl chr20:90,002,030...90,008,033 		JBrowse link
G SLC38A9 solute carrier family 38 member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 4:51,876,430...51,961,914
Ensembl chr 4:51,876,268...51,948,012 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21785164 NCBI chr10:75,076,286...75,097,742
Ensembl chr10:75,075,971...75,096,271 		JBrowse link
G SLC66A3 solute carrier family 66 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 NCBI chr14:96,446,268...96,469,485
Ensembl chr14:96,447,306...96,469,441 		JBrowse link
G SNX10 sorting nexin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr21:31,999,253...32,044,967
Ensembl chr21:31,998,277...32,081,843 		JBrowse link
G SPATA21 spermatogenesis associated 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr20:115,889,975...115,933,026
Ensembl chr20:115,891,903...115,929,898 		JBrowse link
G SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 2:657,315...664,883
Ensembl chr 2:657,623...664,064 		JBrowse link
G STAC3 SH3 and cysteine rich domain 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr11:53,149,572...53,163,036
Ensembl chr11:53,154,755...53,163,090 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12957465 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
G TCF4 transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr18:24,116,595...24,483,037
Ensembl chr18:24,116,547...24,478,228 		JBrowse link
G TERT telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064257 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8807143 NCBI chr14:36,545,641...36,654,213
Ensembl chr14:36,545,875...36,648,237 		JBrowse link
G TMEM132D transmembrane protein 132D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr11:124,425,472...125,256,613 JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24183702
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:18980244 NCBI chr15:16,934,982...16,953,155
Ensembl chr15:16,934,962...16,954,860 		JBrowse link
G TNK2 tyrosine kinase non receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr15:91,187,702...91,232,391
Ensembl chr15:91,201,008...91,232,399 		JBrowse link
G TOP1 DNA topoisomerase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:30132517 NCBI chr 2:22,655,085...22,751,082
Ensembl chr 2:22,651,995...22,751,102 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:30132517 NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701 		JBrowse link
G TOX3 TOX high mobility group box family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28108177 NCBI chr 5:38,197,059...38,304,582
Ensembl chr 5:38,197,066...38,304,264 		JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12378512 PMID:16410370 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G TRIO trio Rho guanine nucleotide exchange factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 4:13,846,753...14,214,647
Ensembl chr 4:13,847,936...14,215,164 		JBrowse link
G TRMT11 tRNA methyltransferase 11 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr13:47,680,321...47,735,103
Ensembl chr13:47,680,332...47,734,857 		JBrowse link
G TTC39A tetratricopeptide repeat domain 39A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 NCBI chr20:81,608,949...81,668,469
Ensembl chr20:81,625,002...81,668,728 		JBrowse link
G TTLL9 tubulin tyrosine ligase like 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 2:36,259,106...36,340,711
Ensembl chr 2:36,268,132...36,332,618 		JBrowse link
G UGDH UDP-glucose 6-dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 NCBI chr27:10,781,324...10,810,595
Ensembl chr27:10,781,502...10,810,817 		JBrowse link
G WDR17 WD repeat domain 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 7:122,141,723...122,257,343
Ensembl chr 7:122,169,204...122,257,337 		JBrowse link
G WSCD1 WSC domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr16:5,452,255...5,504,686
Ensembl chr16:5,318,532...5,507,872 		JBrowse link
G XPA XPA, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24084170 NCBI chr12:41,711,872...41,735,024
Ensembl chr12:41,711,943...41,725,698 		JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24084170 NCBI chr22:50,088,019...50,121,584
Ensembl chr22:50,085,353...50,121,542 		JBrowse link
G YIF1A Yip1 interacting factor homolog A, membrane trafficking protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 1:7,977,690...7,982,313
Ensembl chr 1:7,977,867...7,984,211 		JBrowse link
G ZDHHC2 zinc finger DHHC-type palmitoyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25058030 PMID:28108177 NCBI chr 8:15,241,100...15,311,431
Ensembl chr 8:15,270,598...15,303,323 		JBrowse link
G ZSCAN22 zinc finger and SCAN domain containing 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233941 NCBI chr 6:50,608,188...50,616,961
Ensembl chr 6:50,608,214...50,619,176 		JBrowse link
aflatoxins-related hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHX1 epoxide hydrolase 1 ISO associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535 		JBrowse link
G LOC103223058 glutathione hydrolase light chain 2 ISO associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr19:7,353,922...7,406,392 JBrowse link
childhood hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Pediatric hepatocellular carcinoma ClinVar PMID:9927037 PMID:17483355 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
Experimental Liver Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 ISO RGD PMID:15853769 RGD:1598580 NCBI chr10:54,458,283...54,575,943
Ensembl chr10:54,459,377...54,575,059 		JBrowse link
G ADSL adenylosuccinate lyase ISO protein:increased activity:liver (rat) RGD PMID:2937404 RGD:1598766 NCBI chr19:22,920,971...22,940,468 JBrowse link
G AFP alpha fetoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24012840 PMID:32961231 NCBI chr 7:21,904,225...21,924,105
Ensembl chr 7:21,905,154...21,924,092 		JBrowse link
G AGPS alkylglycerone phosphate synthase ISO RGD PMID:7407223 RGD:1598794 NCBI chr10:62,943,914...63,101,644
Ensembl chr10:62,946,695...63,096,044 		JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:51,086,062...51,108,564
Ensembl chr  X:51,086,066...51,103,505 		JBrowse link
G APOA4 apolipoprotein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 1:108,186,627...108,190,508
Ensembl chr 1:108,186,921...108,189,698 		JBrowse link
G APOC2 apolipoprotein C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 6:38,406,829...38,411,239
Ensembl chr 6:38,409,641...38,410,927 		JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression ISO RGD PMID:26569409 RGD:11344640 NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672 		JBrowse link
G ARRB2 arrestin beta 2 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:21167192 RGD:5509890 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr  X:66,843,519...66,985,655
Ensembl chr  X:66,843,558...66,985,709 		JBrowse link
G ATP7B ATPase copper transporting beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr 3:29,817,712...29,899,302
Ensembl chr 3:29,816,860...29,899,077 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr17:38,492,776...38,502,534
Ensembl chr17:38,492,858...38,501,281 		JBrowse link
G BBC3 BCL2 binding component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 6:40,560,550...40,572,428
Ensembl chr 6:40,561,274...40,567,853 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:10426811 PMID:28100771 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BCL2L1 BCL2 like 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:10426811 PMID:22414765 PMID:28100771 RGD:11353865 NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO mRNA, protein:increased expression:liver RGD PMID:18246794 RGD:2293125 NCBI chr16:70,226,824...70,237,000 JBrowse link
G CA3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 8:80,805,296...80,816,127
Ensembl chr 8:80,805,134...80,816,190 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO protein:increased activity:liver (rat) RGD PMID:13618893 RGD:5132586 NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057 NCBI chr10:113,815,099...113,836,562
Ensembl chr10:113,832,573...113,835,736 		JBrowse link
G CCNB1 cyclin B1 ISO mRNA:increased expression:liver RGD PMID:17342310 RGD:2315991 NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085 		JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:17055752 PMID:28100771 RGD:2289139 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CCNDBP1 cyclin D1 binding protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16501603 NCBI chr26:39,794,572...39,807,919
Ensembl chr26:39,797,083...39,807,827 		JBrowse link
G CCNG2 cyclin G2 ISO RGD PMID:27982046 RGD:151361200 NCBI chr 7:25,657,548...25,667,464
Ensembl chr 7:25,657,441...25,666,254 		JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:19035311 RGD:5491179 NCBI chr  X:111,655,301...111,667,602
Ensembl chr  X:111,655,397...111,666,639 		JBrowse link
G CD63 CD63 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr11:51,673,402...51,677,075
Ensembl chr11:51,672,740...51,676,301 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:decreased expression:liver: RGD PMID:8640740 RGD:8662309 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:19533683 RGD:2315050 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C disease_progression ISO protein:decreased expression:liver (rat)
protein:increased expression:liver (rat)
mRNA:increased expression:liver (rat)		 RGD PMID:3965145 PMID:19533683 PMID:26606000 RGD:11354707 RGD:152998958 RGD:2315050 NCBI chr 1:2,696,382...2,699,054
Ensembl chr 1:2,696,233...2,699,028 		JBrowse link
G COPS5 COP9 signalosome subunit 5 ISO protein:increased expression:liver (rat) RGD PMID:26606000 RGD:11354707 NCBI chr 8:62,905,924...62,925,205
Ensembl chr 8:62,905,906...62,925,201 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 severity ISO mRNA:decreased expression:liver RGD PMID:3387993 RGD:2303406 NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206 		JBrowse link
G CTNNB1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11280770 PMID:20118494 PMID:21147764 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:24,507,121...24,513,830
Ensembl chr 7:24,507,130...24,513,121 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA:increased expression:liver RGD PMID:22687991 RGD:7296954 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11376689 PMID:21147764 NCBI chr26:8,727,996...8,733,254 JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18056438 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) ISO protein:increased activity:liver (rat) RGD PMID:6331524 RGD:5132618 NCBI chr 5:55,161,788...55,177,383
Ensembl chr 5:55,161,916...55,180,896 		JBrowse link
G DTYMK deoxythymidylate kinase ISO protein:increased activity:tumor (rat) RGD PMID:6244089 RGD:5133686 NCBI chr10:127,722,091...127,733,662
Ensembl chr10:127,721,784...127,733,476 		JBrowse link
G ENO2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr11:6,945,243...6,954,959
Ensembl chr11:6,945,413...6,957,304 		JBrowse link
G EPHX1 epoxide hydrolase 1 ISO RGD PMID:7260898 RGD:11252158 NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535 		JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35044086 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G F12 coagulation factor XII ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G FOXM1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15082532 NCBI chr11:2,920,903...2,941,011
Ensembl chr11:2,920,663...2,940,823 		JBrowse link
G GJB1 gap junction protein beta 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:1336494 PMID:18308698 RGD:7349398 NCBI chr  X:61,013,991...61,019,222
Ensembl chr  X:61,017,716...61,018,567 		JBrowse link
G GJB2 gap junction protein beta 2 ISO RGD PMID:1336494 RGD:7349398 NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059 		JBrowse link
G GLUL glutamate-ammonia ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494 PMID:21147764 NCBI chr25:46,988,853...46,998,112
Ensembl chr25:46,989,205...47,000,555 		JBrowse link
G GRP gastrin releasing peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr18:20,496,201...20,508,551
Ensembl chr18:20,496,516...20,507,153 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (rat)		 CTD
RGD		 PMID:2563599 PMID:3124819 PMID:3965145 PMID:7585603 PMID:12016164 More... RGD:152998958 RGD:2317823 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HAT1 histone acetyltransferase 1 ISO protein:increased expression:liver RGD PMID:17182829 RGD:2316578 NCBI chr10:57,412,916...57,482,682
Ensembl chr10:57,412,910...57,482,351 		JBrowse link
G HGF hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11896611 NCBI chr21:67,118,785...67,193,506
Ensembl chr21:67,120,722...67,193,504 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:7955063 PMID:20118494 PMID:21147764 PMID:27517622 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO protein:increased expression:brainstem, cerebral cortex RGD PMID:17258772 RGD:1624998 NCBI chr  X:102,190,355...102,499,928
Ensembl chr  X:102,325,731...102,497,278 		JBrowse link
G IGF2 insulin like growth factor 2 treatment ISO RGD PMID:22425635 RGD:10402567 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO RGD PMID:9652747 PMID:15057872 RGD:2311623 RGD:2311630 NCBI chr13:87,587,717...87,723,795
Ensembl chr13:87,587,907...87,724,116 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:30737368 NCBI chr  X:128,781,975...128,816,039
Ensembl chr  X:128,787,785...128,806,083 		JBrowse link
G IL6 interleukin 6 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (mouse)		 CTD
RGD		 PMID:26297436 PMID:26569409 RGD:11344640 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G INSR insulin receptor disease_progression ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:cytoplasm,liver (rat) RGD PMID:15520221 RGD:2306052 NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592 		JBrowse link
G JAK2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G KAT6A lysine acetyltransferase 6A ISO protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr 8:39,912,120...40,035,776
Ensembl chr 8:39,911,776...39,962,735 		JBrowse link
G KDR kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (rat)		 CTD
RGD		 PMID:8603461 PMID:19533683 RGD:2315050 NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G LOC103233229 cadherin-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494 PMID:25319454 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G LOC103235509 cytochrome P450 2F1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 6:35,270,229...35,286,326 JBrowse link
G LOC103244924 cyclin-G1 ISO RGD PMID:27982046 RGD:151361200 NCBI chr23:65,709,759...65,716,913
Ensembl chr23:65,709,786...65,714,711 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:liver RGD PMID:15520221 RGD:2306052 NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 5:26,536,471...26,545,666
Ensembl chr 5:26,536,532...26,546,461 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682
G MMP2 matrix metallopeptidase 2 ISO mRNA, protein:increased expression, increased activity:liver
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19528495 PMID:19539802 PMID:30603057 RGD:2325734 RGD:2325736 NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO mRNA, protein:increased expression, increased activity:liver RGD PMID:19528495 PMID:19539802 RGD:2325734 RGD:2325736 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (rat)		 CTD
RGD		 PMID:3335218 PMID:9079223 PMID:11280770 PMID:18560566 RGD:10059623 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:liver RGD PMID:10383909 RGD:2325277 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257 		JBrowse link
G NOTCH1 notch receptor 1 ISO protein:increased expression:liver RGD PMID:18942116 RGD:2325310 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:27867096 RGD:13442478 NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 susceptibility ISO RGD PMID:17283114 RGD:14701032 NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17172636 PMID:24769335 PMID:25656644 NCBI chr20:2,724,843...2,752,999
Ensembl chr20:2,744,908...2,756,658 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO human gene in mouse model RGD PMID:16286660 RGD:14975105 NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO protein:decreased expression:liver RGD PMID:7929120 RGD:1642378 NCBI chr16:16,540,096...16,626,251
Ensembl chr16:16,539,985...16,611,279 		JBrowse link
G PLCL1 phospholipase C like 1 (inactive) disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:19533683 RGD:2315050 NCBI chr10:83,291,683...83,640,634
Ensembl chr10:83,574,894...83,642,768 		JBrowse link
G PML PML nuclear body scaffold ISO CTD Direct Evidence: therapeutic CTD PMID:20377131 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:761203 NCBI chr 7:12,201,434...12,242,418
Ensembl chr 7:12,191,784...12,243,488 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO mRNA:increased expression:liver (rat) RGD PMID:2562181 RGD:8693574 NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280 		JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr20:87,267,026...87,277,634
Ensembl chr20:87,267,044...87,279,978 		JBrowse link
G PTGR1 prostaglandin reductase 1 ISO mRNA, protein:increased expression:liver RGD PMID:24853774 RGD:14401713 NCBI chr12:27,918,990...27,999,736 JBrowse link
G RAD51 RAD51 recombinase ISO protein:decreased expression:liver RGD PMID:17219426 RGD:2292638 NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17854601 NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546 		JBrowse link
G RGN regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:44,282,825...44,299,027
Ensembl chr  X:44,285,601...44,299,258 		JBrowse link
G RIDA reactive intermediate imine deaminase A homolog ISO protein:increased expression:liver (rat) RGD PMID:12939504 RGD:9685719 NCBI chr 8:93,014,986...93,031,499 JBrowse link
G RRAS2 RAS related 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr 1:50,527,669...50,607,208
Ensembl chr 1:50,527,699...50,607,871 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO RGD PMID:15224347 RGD:2316863 NCBI chr 1:62,606,112...62,649,979
Ensembl chr 1:62,604,486...62,650,200 		JBrowse link
G RXRA retinoid X receptor alpha ISO mRNA, protein:decreased expression:liver RGD PMID:17786350 RGD:1643105 NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678 		JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:10569800 RGD:1626391 NCBI chr24:72,158,521...72,171,139
Ensembl chr24:72,156,784...72,163,500 		JBrowse link
G SLC31A1 solute carrier family 31 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr12:26,307,308...26,348,701
Ensembl chr12:26,311,334...26,348,694 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 ISO mRNA:increased expression:liver RGD PMID:17498859 RGD:151357003 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
G SNX27 sorting nexin 27 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36029209 NCBI chr20:11,997,768...12,083,929
Ensembl chr20:11,998,527...12,083,528 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15197228 NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407 		JBrowse link
G SQLE squalene epoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 8:119,586,639...119,610,980
Ensembl chr 8:119,586,659...119,611,142 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26297436 PMID:28100771 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver		 CTD
RGD		 PMID:9079223 PMID:16734725 RGD:2317490 NCBI chr14:36,545,641...36,654,213
Ensembl chr14:36,545,875...36,648,237 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365 		JBrowse link
G TK1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr16:70,186,103...70,200,689
Ensembl chr16:70,186,767...70,200,610 		JBrowse link
G TNF tumor necrosis factor treatment
disease_progression		 ISO Morris hepatoma
protein:increased expression:blood serum (mouse)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9063767 PMID:26569409 PMID:28100771 RGD:11344640 RGD:14696818
G TNFRSF10B TNF receptor superfamily member 10b ISO CTD Direct Evidence: therapeutic CTD PMID:18079962 NCBI chr 8:21,101,945...21,150,362
Ensembl chr 8:21,102,267...21,150,267 		JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10626228 PMID:28100771 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G TSC22D1 TSC22 domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15833021 PMID:17533171 NCBI chr 3:22,529,552...22,673,495 JBrowse link
G VIM vimentin ISO RGD PMID:19199359 RGD:6480440 NCBI chr 9:17,183,466...17,191,771
Ensembl chr 9:17,183,388...17,191,829 		JBrowse link
G XDH xanthine dehydrogenase ISO protein:decreased expression:liver RGD PMID:3460692 RGD:13210515 NCBI chr14:76,084,693...76,162,840
Ensembl chr14:76,085,368...76,163,936 		JBrowse link
familial hepatic adenoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Hepatic adenomas, familial | ClinVar Annotator: match by term: LIVER CELL ADENOMAS, FAMILIAL OMIM
ClinVar		 PMID:8866553 PMID:8945470 PMID:9032114 PMID:9045858 PMID:9075818 More... NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
fibrolamellar carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA12 carbonic anhydrase 12 ISO mRNA:increased expression:liver RGD PMID:28304380 RGD:153352326 NCBI chr26:20,162,706...20,221,680
Ensembl chr26:20,162,926...20,224,502 		JBrowse link
G CTNNB1 catenin beta 1 ISO protein:increased tyrosine phosphorylation:exon: RGD PMID:19101982 RGD:14402052 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO protein:increased expression:liver: RGD PMID:24925055 RGD:11055933 NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO mRNA,protein:increased expression:liver (human) RGD PMID:27027723 RGD:151347845 NCBI chr 6:12,743,752...12,759,155 JBrowse link
hemangioma of liver term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA4 gap junction protein alpha 4 ISO ClinVar Annotator: match by term: Hepatic hemangioma ClinVar PMID:33912852 NCBI chr20:98,092,282...98,095,036
Ensembl chr20:98,092,785...98,093,786 		JBrowse link
hepatic angiomyolipoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSC2 TSC complex subunit 2 ISO DNA:mutations:multiple
associated with tuberous sclerosis;DNA:mutations:multiple		 RGD PMID:22251200 PMID:29512829 RGD:21079730 RGD:21079732 NCBI chr 5:1,946,534...1,985,168
Ensembl chr 5:1,946,927...1,987,682 		JBrowse link
hepatoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:1316610 PMID:8381579 PMID:8764128 PMID:9824584 PMID:15311282 More... NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067 		JBrowse link
G APOA1 apolipoprotein A1 ISO mRNA, protein:decreased expression:serum (human) RGD PMID:27974108 RGD:25671440 NCBI chr 1:108,201,967...108,203,902
Ensembl chr 1:108,201,439...108,203,609 		JBrowse link
G ARID1A AT-rich interaction domain 1A ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:26822237 NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672 		JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:11756177 PMID:16832357 PMID:17333338 PMID:19781682 PMID:20305132 More... NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520 		JBrowse link
G AXIN2 axin 2 ISO protein:increased expression:liver: RGD PMID:11809809 RGD:151356508 NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281 		JBrowse link
G BARD1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:26467025 PMID:26580448 PMID:28492532 PMID:35264596 More... NCBI chr10:100,539,827...100,627,718
Ensembl chr10:100,539,527...100,627,675 		JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:9971877 PMID:10717622 PMID:15937982 PMID:17826769 PMID:19941162 More... NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213 		JBrowse link
G CLDN1 claudin 1 severity ISO mRNA,protein:decreased expression:liver, embryonic tissue (human) RGD PMID:16647953 RGD:26884349 NCBI chr15:84,518,464...84,533,587
Ensembl chr15:84,516,478...84,532,969 		JBrowse link
G COL7A1 collagen type VII alpha 1 chain ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr22:9,964,652...9,996,785
Ensembl chr22:9,964,651...9,996,626 		JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:9500465 PMID:9927029 PMID:10192393 PMID:10398436 PMID:10435629 More... NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CUNH11orf65 chromosome unknown C11orf65 homolog ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:21665257 PMID:25085752 PMID:25186627 PMID:25741868 PMID:26787654 More... NCBI chr 1:99,804,191...99,879,834
Ensembl chr 1:99,804,218...99,827,182 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:12270273 PMID:15670717 PMID:16207203 PMID:16392899 PMID:23042628 More... NCBI chr 1:3,243,263...3,257,332
Ensembl chr 1:3,243,313...3,257,487 		JBrowse link
G DIS3L2 DIS3 like 3'-5' exoribonuclease 2 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 PMID:35495172 NCBI chr10:117,959,396...118,350,728
Ensembl chr10:117,960,326...118,352,176 		JBrowse link
G DOCK8 dedicator of cytokinesis 8 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr12:79,060,579...79,298,145
Ensembl chr12:79,060,425...79,298,164 		JBrowse link
G DPEP1 dipeptidase 1 ameliorates ISO human cells in mouse model RGD PMID:31541079 RGD:153344539
G DROSHA drosha ribonuclease III ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 4:30,665,759...30,807,047
Ensembl chr 4:30,665,131...30,795,442 		JBrowse link
G EP300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:24728327 PMID:25741868 PMID:28492532 PMID:29178624 NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 3:81,406,103...81,441,422
Ensembl chr 3:81,405,872...81,436,040 		JBrowse link
G EXT2 exostosin glycosyltransferase 2 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 1:21,077,159...21,282,317
Ensembl chr 1:21,119,987...21,281,635 		JBrowse link
G FAH fumarylacetoacetate hydrolase ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr26:3,223,327...3,259,367
Ensembl chr26:3,223,079...3,258,657 		JBrowse link
G FANCA FA complementation group A ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:24728327 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 5:75,073,161...75,149,110
Ensembl chr 5:75,073,358...75,148,591 		JBrowse link
G FANCD2 FA complementation group D2 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 PMID:28678401 PMID:30306255 NCBI chr22:46,072,797...46,141,107
Ensembl chr22:46,072,761...46,140,713 		JBrowse link
G FANCD2OS FANCD2 opposite strand ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr22:46,144,575...46,150,638
Ensembl chr22:46,144,859...46,145,392 		JBrowse link
G FANCM FA complementation group M ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:28678401 PMID:28881617 More... NCBI chr24:22,255,750...22,327,191
Ensembl chr24:22,256,236...22,329,609 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 PMID:35495172 NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392 		JBrowse link
G FH fumarate hydratase ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr25:78,576,931...78,599,998
Ensembl chr25:78,575,300...78,599,972 		JBrowse link
G FLCN folliculin ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:35495172 NCBI chr16:16,245,840...16,271,465
Ensembl chr16:16,245,715...16,267,698 		JBrowse link
G FLNA filamin A ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr  X:128,657,580...128,683,812
Ensembl chr  X:128,657,393...128,680,531 		JBrowse link
G FRMPD1 FERM and PDZ domain containing 1 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr12:42,835,352...42,981,017
Ensembl chr12:42,835,350...42,980,486 		JBrowse link
G GBA1 glucosylceramidase beta 1 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:12204005 PMID:21228398 PMID:23430543 PMID:25741868 NCBI chr20:8,598,110...8,631,517
Ensembl chr20:8,598,628...8,630,990 		JBrowse link
G GLI3 GLI family zinc finger 3 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr21:16,386,700...16,665,648
Ensembl chr21:16,549,789...16,662,238 		JBrowse link
G GPC3 glypican 3 ISO protein:increased expression:liver (human) RGD PMID:23530909 RGD:243065128 NCBI chr  X:108,688,706...109,143,653 JBrowse link
G IGF2 insulin like growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23958494 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:36965188 NCBI chr 2:27,484,699...27,521,108
Ensembl chr 2:27,484,760...27,522,504 		JBrowse link
G JMJD1C jumonji domain containing 1C ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr 9:67,913,062...68,135,555 JBrowse link
G KDR kinase insert domain receptor ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
G LOC103233229 cadherin-1 ISO protein:increased expression:liver RGD PMID:16465411 RGD:14402053 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:27666373 PMID:28492532 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MKI67 marker of proliferation Ki-67 ameliorates ISO human cells in mouse model RGD PMID:31541079 RGD:153344539 NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866 		JBrowse link
G MSH2 mutS homolog 2 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819 		JBrowse link
G MSH6 mutS homolog 6 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 PMID:35264596 NCBI chr14:59,375,602...59,400,252
Ensembl chr14:59,375,691...59,400,174 		JBrowse link
G MUTYH mutY DNA glycosylase ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr20:87,449,480...87,462,329
Ensembl chr20:87,448,986...87,462,265 		JBrowse link
G NAP1L1 nucleosome assembly protein 1 like 1 ISO mRNA:increased expression:liver (human) RGD PMID:12935928 RGD:9590075 NCBI chr11:71,639,965...71,679,131
Ensembl chr11:71,522,837...71,678,825 		JBrowse link
G NDRG4 NDRG family member 4 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 5:44,402,021...44,452,829
Ensembl chr 5:44,402,453...44,455,245 		JBrowse link
G NYNRIN NYN domain and retroviral integrase containing ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr24:1,380,864...1,401,710
Ensembl chr24:1,381,483...1,401,750 		JBrowse link
G PCNA proliferating cell nuclear antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:11560253 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G RECQL RecQ like helicase ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr11:21,334,601...21,366,943
Ensembl chr11:21,331,584...21,366,979 		JBrowse link
G RECQL4 RecQ like helicase 4 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr 8:138,725,494...138,732,286
Ensembl chr 8:138,725,633...138,732,096 		JBrowse link
G REN renin ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420 		JBrowse link
G RHBDF2 rhomboid 5 homolog 2 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr16:45,176,152...45,205,464
Ensembl chr16:45,194,852...45,204,761 		JBrowse link
G RPS19 ribosomal protein S19 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:12586610 PMID:25741868 PMID:28492532 NCBI chr 6:36,067,959...36,085,581 JBrowse link
G SALL1 spalt like transcription factor 1 ISO embryonal subtype;protein:increased expression:liver, nucleus (human) RGD PMID:23822878 RGD:11556217 NCBI chr 5:36,928,711...36,944,158
Ensembl chr 5:36,927,990...36,943,630 		JBrowse link
G SALL4 spalt like transcription factor 4 ISO Embryonal Hepatoblastoma;protein:increased expression:liver (human) RGD PMID:23822878 RGD:11556217 NCBI chr 2:12,179,721...12,199,629
Ensembl chr 2:12,182,357...12,199,321 		JBrowse link
G SH2B3 SH2B adaptor protein 3 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:20404132 PMID:25741868 NCBI chr11:106,657,601...106,703,940
Ensembl chr11:106,670,685...106,700,619 		JBrowse link
G SLX4 SLX4 structure-specific endonuclease subunit ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:3,281,468...3,308,296 JBrowse link
G SMO smoothened, frizzled class receptor ISO protein:increased expression:liver RGD PMID:21159571 RGD:150521618 NCBI chr21:97,788,955...97,814,549
Ensembl chr21:97,788,624...97,814,709 		JBrowse link
G SPOP speckle type BTB/POZ protein ISO mRNA:decreased expression:liver (human) RGD PMID:24912477 RGD:153298925 NCBI chr16:69,990,554...70,073,241 JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136 		JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11560253 NCBI chr14:36,545,641...36,654,213
Ensembl chr14:36,545,875...36,648,237 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:1565143 PMID:8401536 PMID:8633021 PMID:12826609 PMID:17606709 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:7563486 PMID:8634692 PMID:8707293 PMID:8772572 PMID:8956040 More... NCBI chr22:46,184,621...46,203,065
Ensembl chr22:46,184,756...46,204,428 		JBrowse link
G ZFHX3 zinc finger homeobox 3 ISO protein:increased expression:liver (human) RGD PMID:33368532 RGD:151361168 NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112 		JBrowse link
hepatocellular adenoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA,protein:increased expression:liver: RGD PMID:23912631 RGD:9586718 NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17620307 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G CTNNB1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 treatment ISO RGD PMID:23543859 RGD:14700918 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G HNF1A HNF1 homeobox A susceptibility
exacerbates		 ISO DNA:loss of heterozygosity, mutations:multiple
DNA:mutation: (human)
DNA:frameshift mutation, non-sense mutation:cds:R229X, G55fsX57 (human)		 RGD PMID:12355088 PMID:14598263 PMID:17663417 RGD:14700683 RGD:14700774 RGD:150530291 NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8200073 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase induced ISO aflatoxin B1 induced:DNA:transversion,transition mutations:cds: RGD PMID:8446626 RGD:11568697 NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G LOC103241760 ubiquitin-conjugating enzyme E2 E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr15:67,885,721...68,263,924 JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 ameliorates ISO RGD PMID:26560698 RGD:11342977
G MKI67 marker of proliferation Ki-67 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31939706 NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:17183066 RGD:14696794 NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25656644 NCBI chr20:2,724,843...2,752,999
Ensembl chr20:2,744,908...2,756,658 		JBrowse link
G PTEN phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15199412 PMID:27022031 RGD:1302555 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO MouseDO NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G TMEM70 transmembrane protein 70 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr 8:69,576,786...69,582,478
Ensembl chr 8:69,576,808...69,583,308 		JBrowse link
hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:116,268,241...116,299,509
Ensembl chr 7:116,268,253...116,298,336 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 severity ISO mRNA:decreased expression:liver (human) RGD PMID:16941710 PMID:30580964 RGD:1598532 RGD:24922199 NCBI chr12:34,587,123...34,734,936
Ensembl chr12:34,587,118...34,731,642 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility ISO DNA:polymorphism: :c.3751G>A(human)
DNA:polymorphism: : c.1465C > T(human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17510421 PMID:23488625 PMID:24175826 PMID:25625052 RGD:11041138 RGD:14700904 RGD:14700905 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274 		JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 ISO CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:22022477 NCBI chr21:61,459,344...61,529,017 JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 ISO mRNA:increased expression:liver RGD PMID:25842354 RGD:11535155 NCBI chr16:42,646,316...42,703,124
Ensembl chr16:42,646,812...42,702,852 		JBrowse link
G ABCE1 ATP binding cassette subfamily E member 1 ISO mRNA:increased expression:liver (human) RGD PMID:21932399 RGD:11041873 NCBI chr 7:91,673,359...91,704,774 JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:32171747 RGD:126907997 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr16:30,374,166...30,704,635
Ensembl chr16:30,452,343...30,705,004 		JBrowse link
G ACER3 alkaline ceramidase 3 disease_progression ISO RGD PMID:30097213 RGD:35673325 NCBI chr 1:68,072,323...68,228,036
Ensembl chr 1:68,072,544...68,227,736 		JBrowse link
G ACLY ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr16:64,343,175...64,392,011 JBrowse link
G ACO2 aconitase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr19:24,008,602...24,068,346
Ensembl chr19:24,008,667...24,071,356 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12771043 PMID:15565109 NCBI chr16:45,706,009...45,745,564
Ensembl chr16:45,706,360...45,740,247 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr  X:97,488,414...97,575,251 JBrowse link
G ACTB actin beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:21472284 NCBI chr28:16,195,676...16,197,161
Ensembl chr12:52,426,752...52,427,879 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19514085 NCBI chr 2:65,376,288...65,385,398
Ensembl chr 2:65,376,310...65,385,918 		JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:4,677,237...4,718,825
Ensembl chr12:4,677,229...4,714,386 		JBrowse link
G ADD1 adducin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr27:45,811,611...45,901,277
Ensembl chr27:45,813,496...45,900,778 		JBrowse link
G ADGRG7 adhesion G protein-coupled receptor G7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:80,202,524...80,275,281
Ensembl chr22:80,203,710...80,273,248 		JBrowse link
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:47,226,787...47,248,518
Ensembl chr 7:47,226,191...47,248,234 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing susceptibility ISO DNA:SNP:intron:+276T>G (rs1501299) (human) RGD PMID:23740135 RGD:14401720 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391 		JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:558,876...562,959
Ensembl chr14:561,057...562,400 		JBrowse link
G AFP alpha fetoprotein treatment
disease_progression
severity		 ISO protein:increased expression:serum (human)
associated with hepatitis B
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9029167 PMID:15276417 PMID:22147961 PMID:22392353 PMID:24012840 More... RGD:125097525 RGD:126790579 RGD:126790583 RGD:14401581 RGD:152177911 NCBI chr 7:21,904,225...21,924,105
Ensembl chr 7:21,905,154...21,924,092 		JBrowse link
G AICDA activation induced cytidine deaminase ISO RGD PMID:18997814 RGD:127285629 NCBI chr11:8,426,920...8,438,331
Ensembl chr11:8,428,922...8,431,641 		JBrowse link
G AK3 adenylate kinase 3 ISO protein:decreased expression:liver RGD PMID:17203974 RGD:13842477 NCBI chr12:74,801,673...74,832,838
Ensembl chr12:74,801,671...74,835,475 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32805337 NCBI chr20:87,228,348...87,245,511
Ensembl chr20:87,228,189...87,245,466 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 treatment
exacerbates		 ISO mRNA:increased expression:liver
ClinVar Annotator: match by term: Hepatocellular cancer		 RGD
ClinVar		 PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... RGD:151893509 RGD:152177911 RGD:408364960 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO protein:increased phosphorylation:liver (mouse)
protein:increased phosphorylation:liver cancer cell (rat)		 RGD PMID:19309364 PMID:28100771 RGD:127285675 RGD:2313299 NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781 		JBrowse link
G ALB albumin susceptibility ISO associated with hepatitis C;protein:decreased expression:serum
protein:decreased expression:serum (human)		 RGD PMID:22392353 PMID:23892757 PMID:29040987 RGD:11035269 RGD:125097525 RGD:14694841 NCBI chr 7:21,872,036...21,890,095
Ensembl chr 7:21,876,132...21,891,407 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member susceptibility
severity
no_association		 ISO associated with alcohol use disorder;DNA:missense mutation:cds: (human)
protein:decreased expression: liver (human)
DNA:missense mutation:cds, exon 12:p.E487K (human)
DNA:missense mutation:cds: (rs671) (human)
mRNA, protein:decreased expression:liver (human)
associated with alcoholic liver cirrhosis;DNA:missense mutation:cds:p.E487K (human)
associated with hepatitis B;DNA;missense mutation, haplotype:cds: (rs671) (human)
DNA:missense mutation:exon 12: (human)
associated with hepatitis C:DNA:SNP:exon 12 (human)		 RGD PMID:1916152 PMID:10737710 PMID:12940444 PMID:18439068 PMID:25778454 More... RGD:11054822 RGD:14696699 RGD:14696778 RGD:14696779 RGD:14700899 RGD:15036809 RGD:15042857 RGD:15042859 RGD:15042862 NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374 		JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr23:29,539,897...29,589,004 JBrowse link
G ALDOC aldolase, fructose-bisphosphate C ISO mRNA:increased expression:liver RGD PMID:3830170 RGD:2301136 NCBI chr16:22,342,750...22,346,811
Ensembl chr16:22,341,318...22,346,620 		JBrowse link
G ALX4 ALX homeobox 4 ameliorates ISO mRNA, protein:decreased expression:liver RGD PMID:28081728 PMID:31132711 RGD:153323329 RGD:153323330 NCBI chr 1:21,051,413...21,099,159
Ensembl chr 1:21,051,580...21,097,605 		JBrowse link
G ANGPTL6 angiopoietin like 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:9,162,219...9,175,163 JBrowse link
G ANK3 ankyrin 3 ISO protein:decreased expression:liver RGD PMID:26652480 RGD:153344559 NCBI chr 9:70,549,665...71,253,928
Ensembl chr 9:70,893,260...71,254,245 		JBrowse link
G ANLN anillin actin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:22,034,213...22,099,207
Ensembl chr21:22,034,259...22,099,158 		JBrowse link
G ANTXR1 ANTXR cell adhesion molecule 1 treatment ISO RGD PMID:20650339 RGD:9684932 NCBI chr14:37,849,911...38,116,339
Ensembl chr14:37,877,436...38,115,938 		JBrowse link
G ANXA10 annexin A10 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 7:114,287,291...114,449,532
Ensembl chr 7:114,388,038...114,449,277 		JBrowse link
G ANXA2 annexin A2 ISO mRNA, protein:increased expression:liver (human) RGD PMID:33675609 RGD:152999436 NCBI chr26:23,100,000...23,147,687
Ensembl chr26:23,099,992...23,145,457 		JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr14:37,297,960...37,384,187
Ensembl chr14:37,297,652...37,344,884 		JBrowse link
G ANXA6 annexin A6 disease_progression ISO associated with tumor vascularization; protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr23:53,657,377...53,714,828
Ensembl chr23:53,657,718...53,714,850 		JBrowse link
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma OMIM
ClinVar		 PMID:1316610 PMID:8381579 PMID:8381580 PMID:9536098 PMID:9585611 More... NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067 		JBrowse link
G APCS amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr20:4,360,955...4,363,810
Ensembl chr20:4,358,654...4,362,095 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:25109342 PMID:33841550 RGD:152998960 NCBI chr29:20,978,878...20,981,393 JBrowse link
G APLN apelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:104,885,639...104,896,371
Ensembl chr  X:104,888,996...104,895,014 		JBrowse link
G APOA1 apolipoprotein A1 disease_progression ISO CTD Direct Evidence: marker/mechanism
associated with hepatitis B;
protein:decreased expression:plasma (human)		 CTD
RGD		 PMID:21472284 PMID:23935864 PMID:31211449 RGD:153350082 RGD:25671438 NCBI chr 1:108,201,967...108,203,902
Ensembl chr 1:108,201,439...108,203,609 		JBrowse link
G APOA2 apolipoprotein A2 ISO associated with hepatitis B; mRNA:increased expression:liver RGD PMID:31211449 RGD:153350082 NCBI chr20:2,757,939...2,760,356
Ensembl chr20:2,759,237...2,760,686 		JBrowse link
G APOA4 apolipoprotein A4 disease_progression ISO associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr 1:108,186,627...108,190,508
Ensembl chr 1:108,186,921...108,189,698 		JBrowse link
G APOC2 apolipoprotein C2 ISO associated with hepatitis B; mRNA:increased expression:liver RGD PMID:31211449 RGD:153350082 NCBI chr 6:38,406,829...38,411,239
Ensembl chr 6:38,409,641...38,410,927 		JBrowse link
G APOC3 apolipoprotein C3 susceptibility
disease_progression		 ISO associated with Chronic Hepatitis B;DNA:SNP: :rs2854116(human)
associated with hepatitis B;		 RGD PMID:27547913 PMID:31211449 RGD:153344620 RGD:153350082 NCBI chr 1:108,196,283...108,199,274
Ensembl chr 1:108,196,939...108,199,342 		JBrowse link
G APOC4 apolipoprotein C4 disease_progression ISO associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr 6:38,391,454...38,406,692
Ensembl chr 6:38,398,471...38,406,697 		JBrowse link
G APOE apolipoprotein E ISO protein:increased expression:liver, serum (mouse) RGD PMID:21644509 RGD:6903288 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G APOF apolipoprotein F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:52,316,413...52,318,956
Ensembl chr11:52,316,800...52,318,659 		JBrowse link
G APRT adenine phosphoribosyltransferase ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr 5:74,196,858...74,199,789
Ensembl chr 5:74,194,013...74,199,891 		JBrowse link
G AR androgen receptor ISO CTD Direct Evidence: therapeutic CTD PMID:18639551 NCBI chr  X:57,380,587...57,553,613
Ensembl chr  X:57,380,611...57,546,776 		JBrowse link
G ARG1 arginase 1 disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:17210712 PMID:30901224 RGD:152995286 RGD:4140476 NCBI chr13:41,971,955...41,983,372
Ensembl chr13:41,971,802...41,983,049 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 exacerbates ISO protein:decreased expression:liver (human) RGD PMID:31136984 RGD:401901276 NCBI chr16:12,125,543...12,328,203
Ensembl chr16:12,125,574...12,330,501 		JBrowse link
G ARHGEF39 Rho guanine nucleotide exchange factor 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:44,937,488...44,941,708
Ensembl chr12:44,937,923...44,944,842 		JBrowse link
G ARID1A AT-rich interaction domain 1A exacerbates
treatment		 ISO associated with non-alcoholic steatohepatitis
mRNA, protein:decreased expression:liver (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (human)
human gene in mouse model		 RGD
CTD		 PMID:22561517 PMID:22634756 PMID:22922871 PMID:25975202 PMID:26569409 More... RGD:11344640 RGD:125097485 RGD:125097495 RGD:125097519 RGD:126790634 NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672 		JBrowse link
G ARID1B AT-rich interaction domain 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr13:84,351,298...84,799,691 JBrowse link
G ARID2 AT-rich interaction domain 2 exacerbates
disease_progression		 ISO CTD Direct Evidence: marker/mechanism
associated with hepatitis B;protein:decreased expression:liver		 RGD
CTD		 PMID:21822264 PMID:22634756 PMID:25701229 PMID:27351279 PMID:28498550 More... RGD:150340708 RGD:150340711 RGD:150340712 RGD:150429631 NCBI chr11:41,933,650...42,117,495
Ensembl chr11:42,028,083...42,118,892 		JBrowse link
G ARID3A AT-rich interaction domain 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:35179300 NCBI chr 6:667,426...727,987
Ensembl chr 6:680,965...727,843 		JBrowse link
G ARRB2 arrestin beta 2 treatment ISO RGD PMID:33841550 RGD:152998960 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385 		JBrowse link
G ASF1B anti-silencing function 1B histone chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:12,760,865...12,773,423 JBrowse link
G ASL argininosuccinate lyase disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr28:1,782,434...1,800,581
Ensembl chr28:1,782,553...1,802,517 		JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) ISO protein:increased activity:serum (rat) RGD PMID:10081 RGD:2316006 NCBI chr21:51,244,514...51,264,694
Ensembl chr21:51,247,742...51,265,241 		JBrowse link
G ASPG asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr24:82,021,590...82,049,281
Ensembl chr24:82,021,726...82,049,355 		JBrowse link
G ASPM assembly factor for spindle microtubules disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18676753 PMID:28284560 RGD:13439743 NCBI chr25:32,269,518...32,334,617
Ensembl chr25:32,281,424...32,334,977 		JBrowse link
G ASS1 argininosuccinate synthase 1 disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:12359751 PMID:30901224 RGD:152995286 RGD:4140479 NCBI chr12:7,643,484...7,701,334 JBrowse link
G ATG101 autophagy related 101 disease_progression ISO RGD PMID:35592424 RGD:153350091 NCBI chr11:48,243,200...48,251,129
Ensembl chr11:48,243,216...48,251,371 		JBrowse link
G ATG7 autophagy related 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29191453 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G ATM ATM serine/threonine kinase exacerbates ISO protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12866955 PMID:19919837 RGD:126781750 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b ISO associated with hepatitis C RGD PMID:18932288 RGD:14696822 NCBI chr20:22,150,488...22,162,740
Ensembl chr20:22,150,239...22,162,312 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr16:46,625,512...46,630,613 JBrowse link
G AURKA aurora kinase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:7,730,060...7,753,167
Ensembl chr 2:7,734,128...7,752,395 		JBrowse link
G AURKB aurora kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:7,571,255...7,583,034
Ensembl chr16:7,570,538...7,582,959 		JBrowse link
G AXIN1 axin 1 disease_progression ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
protein:decreased expression:liver (human)
associated with Hepatitis B, Chronic,DNA:SNP, haplotype:exon:(rs1805105) T>C (human)		 OMIM
ClinVar
RGD		 PMID:10700176 PMID:25741868 PMID:26968103 PMID:28492532 PMID:31514071 More... RGD:14402039 RGD:150530482 NCBI chr 5:233,520...295,134
Ensembl chr 5:234,060...290,575 		JBrowse link
G AXIN2 axin 2 ISO protein:increased expression:liver: RGD PMID:11809809 RGD:151356508 NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding disease_progression ISO associated with hepatitis B;mRNA:decreased expression:liver RGD PMID:22625427 PMID:26902423 PMID:27993894 RGD:153350130 RGD:153350132 RGD:153350133 NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363 		JBrowse link
G AZIN1 antizyme inhibitor 1 disease_progression ISO RNA:increased editing:liver RGD PMID:23291631 RGD:14700705 NCBI chr 8:97,679,775...97,717,486
Ensembl chr 8:97,679,468...97,696,928 		JBrowse link
G BANF1 barrier to autointegration nuclear assembly factor 1 treatment ISO mRNA, protein:increased expression:liver (rat)
mRNA, protein:increased expression:liver (human)		 RGD PMID:29059470 RGD:155791679 NCBI chr 1:8,254,186...8,255,571
Ensembl chr 1:8,253,884...8,255,572 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:33841550 RGD:152998960 NCBI chr 6:42,186,028...42,193,105 JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO mRNA:increased expression:liver (mouse) RGD PMID:28100771 PMID:33841550 RGD:127285675 RGD:152998960 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BCL2L1 BCL2 like 1 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (mouse)		 CTD
RGD		 PMID:10629087 PMID:11509945 PMID:28100771 PMID:33841550 RGD:127285675 RGD:152998960 NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470 		JBrowse link
G BCORL1 BCL6 corepressor like 1 disease_progression ISO RGD PMID:26879601 PMID:29679906 RGD:11556159 RGD:150340705 NCBI chr  X:105,238,616...105,314,326
Ensembl chr  X:105,240,043...105,314,553 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 4:73,331,551...73,352,259
Ensembl chr 4:73,332,259...73,352,434 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 4:73,289,836...73,310,312
Ensembl chr 4:73,289,652...73,312,358 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 exacerbates
treatment
ameliorates		 ISO mRNA, protein:increased expression:liver (human)
human cell line in a mouse model
associated with hepatitis B;mRNA, protein:increased expression:liver (human)		 RGD PMID:22682366 PMID:22820591 PMID:30210622 PMID:30368883 PMID:33310033 RGD:152998937 RGD:152998984 RGD:152998986 RGD:152998988 RGD:152999010 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression ISO CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:16086872 PMID:20514400 PMID:31964418 RGD:153344516 NCBI chr16:70,226,824...70,237,000 JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 exacerbates ISO mRNA:increased expression:liver (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:965,811...970,983 JBrowse link
G BLZF1 basic leucine zipper nuclear factor 1 disease_progression ISO RGD PMID:26342799 RGD:14398326 NCBI chr25:59,665,035...59,685,304
Ensembl chr25:59,664,280...59,685,376 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger treatment ISO RGD PMID:26919246 RGD:14928318 NCBI chr 9:22,095,592...22,104,894 JBrowse link
G BMPER BMP binding endothelial regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:24,255,857...24,500,790
Ensembl chr21:24,255,866...24,500,720 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27222248 NCBI chr21:109,495,525...109,690,261 JBrowse link
G BSG basigin (Ok blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr 6:309,579...320,209
Ensembl chr 6:309,506...321,785 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18393292 NCBI chr25:26,032,404...26,036,500
Ensembl chr25:26,034,632...26,036,538 		JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:13,647,342...13,698,061
Ensembl chr14:13,647,462...13,697,932 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:42,769,955...42,855,353
Ensembl chr26:42,792,830...42,855,306 		JBrowse link
G C3 complement C3 ISO RGD PMID:23245919 RGD:11040806 NCBI chr 6:6,250,422...6,289,264 JBrowse link
G C9 complement C9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 4:38,082,751...38,165,886
Ensembl chr 4:38,082,457...38,164,164 		JBrowse link
G CA12 carbonic anhydrase 12 ameliorates
disease_progression		 ISO mRNA:altered expression:liver RGD PMID:29900055 PMID:31934040 PMID:35362480 RGD:153352325 RGD:153352328 RGD:155226869 NCBI chr26:20,162,706...20,221,680
Ensembl chr26:20,162,926...20,224,502 		JBrowse link
G CA2 carbonic anhydrase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 8:80,830,963...80,848,245
Ensembl chr 8:80,830,939...80,848,707 		JBrowse link
G CA9 carbonic anhydrase 9 ISO mRNA:altered expression:liver RGD PMID:29900055 RGD:155226869 NCBI chr12:44,921,530...44,929,504
Ensembl chr12:44,921,665...44,928,831 		JBrowse link
G CAB39 calcium binding protein 39 disease_progression ISO RGD PMID:28605041 RGD:14398832 NCBI chr10:116,749,173...116,860,814
Ensembl chr10:116,798,825...116,861,332 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO DNA:amplification:cds (rat)
mRNA:increased expression:liver		 RGD PMID:2888462 PMID:2914957 PMID:7053379 RGD:10755426 RGD:2303530 RGD:5132587 NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914 		JBrowse link
G CADM1 cell adhesion molecule 1 ISO DNA, mRNA, protein:hypermethylation, decreased expression:promoter:liver RGD PMID:17428255 RGD:2289095 NCBI chr 1:106,539,262...106,876,397
Ensembl chr 1:106,539,136...106,606,637 		JBrowse link
G CADM2 cell adhesion molecule 2 disease_progression ISO mRNA, protein:decreased expression:liver RGD PMID:24240726 RGD:15092075 NCBI chr22:90,879,537...91,994,144 JBrowse link
G CALML3 calmodulin like 3 severity ISO protein:decreased expression:liver (human) RGD PMID:29445139 RGD:151665319 NCBI chr 9:5,634,739...5,636,634
Ensembl chr 9:5,635,456...5,635,905 		JBrowse link
G CALR calreticulin treatment
exacerbates		 ISO human cells and recombinant gene in a mouse model
protein:increased expression:liver (human)		 RGD PMID:12096119 PMID:24997628 PMID:27055635 RGD:150521681 RGD:150521690 RGD:150521691 NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792 		JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:23651211 RGD:18337283 NCBI chr20:112,064,718...112,068,505
Ensembl chr20:112,065,581...112,067,256 		JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:54,575,289...54,742,565
Ensembl chr17:54,574,145...54,742,757 		JBrowse link
G CAPN3 calpain 3 ISO mRNA:decreased expression:skeletal muscle RGD PMID:10806331 RGD:1600777 NCBI chr26:40,568,320...40,657,443
Ensembl chr26:40,568,885...40,625,597 		JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA,protein:increased expression:liver: RGD PMID:23912631 RGD:9586718 NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:29133031 PMID:33841550 RGD:13782296 RGD:152998960 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G CASP8 caspase 8 treatment
severity		 ISO associated with hepatitis B;DNA:insertion/deletion:promoter: (rs3834129) (human) OMIM
RGD		 PMID:28643196 PMID:29133031 RGD:13782296 RGD:14695027 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:29133031 RGD:13782296 NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930 		JBrowse link
G CAT catalase disease_progression ISO associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-262T>C (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:21907168 PMID:33010264 RGD:27095879 NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592 		JBrowse link
G CBFB core-binding factor subunit beta ISO mRNA:decreased expression:liver RGD PMID:17094378 RGD:126775147 NCBI chr 5:60,356,303...60,445,793
Ensembl chr 5:60,356,272...60,445,729 		JBrowse link
G CBL Cbl proto-oncogene disease_progression ISO RGD PMID:26474280 RGD:11536137 NCBI chr 1:110,581,049...110,679,284
Ensembl chr 1:110,581,143...110,674,481 		JBrowse link
G CBX2 chromobox 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr16:71,741,476...71,749,234
Ensembl chr16:71,741,500...71,751,817 		JBrowse link
G CBX4 chromobox 4 disease_progression ISO protein:increased expression:cytoplasm: RGD PMID:23943028 PMID:24838576 RGD:9586738 RGD:9586739 NCBI chr16:71,795,919...71,802,184
Ensembl chr16:71,795,862...71,802,051 		JBrowse link
G CBX7 chromobox 7 ISO mRNA:decreased expression:liver RGD PMID:22041561 RGD:9587355 NCBI chr19:21,776,618...21,798,525
Ensembl chr19:21,775,931...21,798,309 		JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:20,054,281...20,363,024
Ensembl chr18:20,271,874...20,309,784 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr16:27,868,925...27,890,143 JBrowse link
G CCL13 C-C motif chemokine ligand 13 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr16:27,864,260...27,867,457
Ensembl chr16:27,865,318...27,867,415 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO RNA:increased expression:liver RGD PMID:12679798 PMID:22402625 PMID:27980102 RGD:14995459 RGD:14995468 RGD:14995927 NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility
treatment		 ISO associated with alcoholic liver cirrhosis;DNA:SNP:promoter:-403G>A(human)
DNA:polymorphisms:promoter:-403G>A,-28C>G (human)		 RGD PMID:21610221 PMID:22374185 PMID:28011329 RGD:14995306 RGD:14995333 RGD:14995338 NCBI chr16:29,351,214...29,361,317 JBrowse link
G CCN1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17699798 NCBI chr20:47,783,270...47,786,216
Ensembl chr20:47,783,935...47,785,997 		JBrowse link
G CCNA1 cyclin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12029619 NCBI chr 3:14,979,775...14,992,609
Ensembl chr 3:14,982,392...14,993,562 		JBrowse link
G CCNB1 cyclin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085 		JBrowse link
G CCNB2 cyclin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:24,389,654...24,408,976
Ensembl chr26:24,389,642...24,409,346 		JBrowse link
G CCND1 cyclin D1 susceptibility ISO mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism
associated with Hepatitis B, Chronic;DNA:SNP:splice-site mutation:870G>A (human)		 RGD
CTD		 PMID:12029619 PMID:19919837 PMID:22649188 PMID:25822088 PMID:25851350 More... RGD:127285675 RGD:14401586 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CCND2 cyclin D2 disease_progression
susceptibility
severity		 ISO associated with hepatitis B
associated with Chronic Hepatitis C;DNA:SNP: :rs1049606(human)
DNA:hypermethylation:CpG site		 RGD PMID:22004425 PMID:31059558 PMID:33320844 RGD:151664743 RGD:151665109 RGD:151665169 NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661 		JBrowse link
G CCNE1 cyclin E1 ameliorates ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12029619 PMID:17196522 PMID:22634754 PMID:28100771 PMID:29551768 RGD:127285675 RGD:153297807 RGD:2289277 NCBI chr 6:24,879,923...24,888,985 JBrowse link
G CCNF cyclin F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:2,302,249...2,336,188
Ensembl chr 5:2,302,341...2,335,270 		JBrowse link
G CCNG2 cyclin G2 ISO RGD PMID:27982046 RGD:151361200 NCBI chr 7:25,657,548...25,667,464
Ensembl chr 7:25,657,441...25,666,254 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr22:7,634,205...7,641,380 JBrowse link
G CD163 CD163 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:7,501,562...7,536,332
Ensembl chr11:7,501,150...7,536,295 		JBrowse link
G CD274 CD274 molecule disease_progression ISO associated with hepatitis B
CTD Direct Evidence: marker/mechanism
associated with hepatitis B		 RGD
CTD		 PMID:21912640 PMID:22396772 PMID:30267213 RGD:40818240 RGD:41410800 NCBI chr12:74,038,844...74,060,662
Ensembl chr12:74,041,767...74,056,806 		JBrowse link
G CD276 CD276 molecule ISO CTD Direct Evidence: therapeutic CTD PMID:16217749 NCBI chr26:9,772,948...9,794,395 JBrowse link
G CD34 CD34 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:21,534,969...21,559,951
Ensembl chr25:21,534,983...21,561,215 		JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:19016771 RGD:2313413 NCBI chr  X:111,655,301...111,667,602
Ensembl chr  X:111,655,397...111,666,639 		JBrowse link
G CD5L CD5 molecule like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:6,059,103...6,074,657
Ensembl chr20:6,065,620...6,070,904 		JBrowse link
G CD68 CD68 molecule severity ISO protein:increased expression:liver (human) RGD PMID:28656201 RGD:40924686 NCBI chr16:6,956,633...6,959,645
Ensembl chr16:6,957,212...6,959,042 		JBrowse link
G CDC20 cell division cycle 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:89,449,008...89,453,263
Ensembl chr20:89,444,165...89,453,044 		JBrowse link
G CDC25C cell division cycle 25C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:40,960,154...41,013,016
Ensembl chr23:40,960,572...41,006,984 		JBrowse link
G CDC27 cell division cycle 27 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar NCBI chr16:59,497,731...59,564,298
Ensembl chr16:59,497,713...59,564,480 		JBrowse link
G CDC45 cell division cycle 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:6,232,610...6,275,743
Ensembl chr19:6,231,591...6,275,294 		JBrowse link
G CDC6 cell division cycle 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:65,873,341...65,888,180
Ensembl chr16:65,871,627...65,888,217 		JBrowse link
G CDCA2 cell division cycle associated 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:23,582,062...23,631,590
Ensembl chr 8:23,582,744...23,632,045 		JBrowse link
G CDCA3 cell division cycle associated 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:6,882,125...6,885,311
Ensembl chr11:6,881,504...6,885,118 		JBrowse link
G CDCA5 cell division cycle associated 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:9,151,503...9,157,412
Ensembl chr 1:9,151,712...9,157,456 		JBrowse link
G CDCA8 cell division cycle associated 8 disease_progression ISO mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr20:95,151,814...95,169,111
Ensembl chr20:95,151,752...95,169,033 		JBrowse link
G CDH13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18425332 PMID:18553387 PMID:28284560 NCBI chr 5:68,048,655...69,213,102
Ensembl chr 5:68,451,894...69,211,534 		JBrowse link
G CDK1 cyclin dependent kinase 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)		 CTD
RGD		 PMID:19136513 PMID:28284560 RGD:2316317 NCBI chr 9:70,475,736...70,492,947 JBrowse link
G CDK12 cyclin dependent kinase 12 exacerbates ISO mRNA, protein:increased expression:liver (human) RGD PMID:31519701 RGD:151361172 NCBI chr16:66,612,238...66,709,437
Ensembl chr16:66,623,785...66,708,755 		JBrowse link
G CDK13 cyclin dependent kinase 13 onset ISO DNA:amplification: : RGD PMID:22912832 RGD:155641228 NCBI chr21:18,551,273...18,688,889
Ensembl chr21:18,553,446...18,688,525 		JBrowse link
G CDK14 cyclin dependent kinase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr21:57,752,126...58,434,621
Ensembl chr21:57,751,721...58,335,258 		JBrowse link
G CDK4 cyclin dependent kinase 4 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26189965 PMID:33841550 RGD:152998960 NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO OMIM:114550 MouseDO NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20698225 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C severity ISO protein:decreased expression:liver (human) RGD PMID:26606000 RGD:11354707 NCBI chr 1:2,696,382...2,699,054
Ensembl chr 1:2,696,233...2,699,028 		JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:81,964,164...81,970,891
Ensembl chr20:81,963,562...81,968,450 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 severity
treatment		 ISO associated with alcoholism; protein:increased expression:liver
protein:decreased expression:liver
mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:22390936 PMID:23292002 PMID:27314282 PMID:28284560 RGD:15090800 RGD:15090801 RGD:15090802 NCBI chr24:31,554,461...31,578,916
Ensembl chr24:31,554,510...31,579,664 		JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:74,190,409...74,196,589
Ensembl chr 5:74,190,947...74,195,972 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16288022 PMID:21785164 NCBI chr 6:28,342,506...28,345,759
Ensembl chr 6:28,343,907...28,344,977 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:14563831 PMID:30659195 RGD:40903042 NCBI chr 2:13,780,538...13,782,639
Ensembl chr 2:13,781,160...13,782,194 		JBrowse link
G CEBPD CCAAT enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr 8:43,873,075...43,874,375 JBrowse link
G CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:10,046,361...10,073,689
Ensembl chr22:10,045,900...10,072,395 		JBrowse link
G CENPA centromere protein A ISO protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:21956590 PMID:28284560 RGD:36947377 NCBI chr14:80,838,049...80,847,609
Ensembl chr14:80,839,335...80,846,608 		JBrowse link
G CENPE centromere protein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:51,212,266...51,300,153 JBrowse link
G CENPF centromere protein F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:14,914,805...14,972,811
Ensembl chr25:14,914,809...14,972,796 		JBrowse link
G CENPM centromere protein M ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:24,471,420...24,481,271
Ensembl chr19:24,471,178...24,481,239 		JBrowse link
G CENPU centromere protein U ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:130,653,805...130,697,329
Ensembl chr 7:130,653,967...130,697,233 		JBrowse link
G CENPW centromere protein W ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:47,363,726...47,372,472
Ensembl chr13:47,363,717...47,372,164 		JBrowse link
G CEP131 centrosomal protein 131 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:73,138,784...73,172,677
Ensembl chr16:73,139,683...73,170,339 		JBrowse link
G CEP164 centrosomal protein 164 susceptibility ISO associated with Chronic Hepatitis C;DNA:SNP: :rs573455 (human) RGD PMID:22004425 RGD:151665169 NCBI chr 1:108,690,196...108,787,175
Ensembl chr 1:108,701,884...108,790,678 		JBrowse link
G CEP55 centrosomal protein 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:86,746,658...86,772,052
Ensembl chr 9:86,749,730...86,771,115 		JBrowse link
G CETP cholesteryl ester transfer protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:42,909,994...42,936,277
Ensembl chr 5:42,910,226...42,936,277 		JBrowse link
G CHAF1B chromatin assembly factor 1 subunit B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:80,379,637...80,409,626
Ensembl chr 2:80,380,425...80,409,687 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 exacerbates ISO mRNA:increased expression:liver (human)
protein:increased expression:liver (human)		 RGD PMID:26095183 PMID:28486105 PMID:32070428 RGD:11571740 RGD:153323299 RGD:153323308 NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351 		JBrowse link
G CHD5 chromodomain helicase DNA binding protein 5 ISO mRNA:decreased expression:liver RGD PMID:26517514 RGD:11537550 NCBI chr20:125,558,640...125,635,748
Ensembl chr20:125,558,713...125,631,277 		JBrowse link
G CKAP2L cytoskeleton associated protein 2 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:15,753,596...15,780,051
Ensembl chr14:15,751,721...15,779,994 		JBrowse link
G CKAP4 cytoskeleton associated protein 4 disease_progression ISO associated with tumor vascularization; mRNA,protein:increased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr11:101,460,989...101,471,104
Ensembl chr11:101,460,759...101,471,474 		JBrowse link
G CLDN1 claudin 1 severity ISO protein:decreased expression:liver (human)
protein:increased expression:liver (human)
associated with liver cirrhosis;protein:increased expression:liver (human)		 RGD PMID:17270214 PMID:24696415 PMID:24815833 RGD:26884345 RGD:26884348 RGD:26884352 NCBI chr15:84,518,464...84,533,587
Ensembl chr15:84,516,478...84,532,969 		JBrowse link
G CLEC1B C-type lectin domain family 1 member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:9,869,686...9,875,998
Ensembl chr11:9,869,768...9,875,707 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility
disease_progression		 ISO DNA:SNPs::rs401681(human)
DNA:SNP: :rs401681(human)		 RGD PMID:25339005 PMID:29042796 RGD:150530496 RGD:150537100 NCBI chr 4:1,140,272...1,162,663
Ensembl chr 4:1,140,132...1,162,898 		JBrowse link
G CLTRN collectrin, amino acid transport regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:14,103,046...14,154,936
Ensembl chr  X:14,102,497...14,154,123 		JBrowse link
G CNDP1 carnosine dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:5,317,101...5,364,323
Ensembl chr18:5,317,542...5,364,277 		JBrowse link
G CNOT9 CCR4-NOT transcription complex subunit 9 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 NCBI chr10:104,473,215...104,502,321
Ensembl chr10:104,473,216...104,503,007 		JBrowse link
G CNTNAP4 contactin associated protein family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:61,706,427...61,984,656
Ensembl chr 5:61,706,444...61,982,587 		JBrowse link
G COL15A1 collagen type XV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:40,355,643...40,483,794 JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain severity ISO Protein:increased expression RGD PMID:15739185 RGD:1600906 NCBI chr 2:89,129,674...89,186,490 JBrowse link
G COLEC10 collectin subfamily member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:113,663,768...113,704,070
Ensembl chr 8:113,664,263...113,702,720 		JBrowse link
G COMT catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422 		JBrowse link
G COPS5 COP9 signalosome subunit 5 severity ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)		 CTD
RGD		 PMID:20698225 PMID:26606000 RGD:11354707 NCBI chr 8:62,905,924...62,925,205
Ensembl chr 8:62,905,906...62,925,201 		JBrowse link
G COX7B2 cytochrome c oxidase subunit 7B2, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr27:3,353,319...3,503,408
Ensembl chr27:3,503,043...3,503,285 		JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:85,325,768...85,569,192
Ensembl chr 9:85,331,466...85,525,688 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206 		JBrowse link
G CREBBP CREB binding protein ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:71,203,335...71,223,179
Ensembl chr 4:71,205,932...71,223,172 		JBrowse link
G CRP C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr20:4,232,262...4,235,826
Ensembl chr20:4,232,913...4,235,377 		JBrowse link
G CSF1R colony stimulating factor 1 receptor exacerbates
severity		 ISO mRNA:increased expression:liver (human)
protein:increased expression: liver (human)
protein:increased expression:liver (human)
DNA:hypomethylation:promoter (human)		 RGD PMID:11412385 PMID:14969845 PMID:20551429 PMID:32724427 PMID:32760707 RGD:150524279 RGD:150524282 RGD:150524286 RGD:150524301 RGD:150524302 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304 		JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO RGD PMID:12731087 RGD:10450243 NCBI chr23:34,906,987...34,911,252
Ensembl chr23:34,908,911...34,911,140 		JBrowse link
G CSK C-terminal Src kinase ISO protein:decreased expression:liver RGD PMID:9918913 RGD:5134372 NCBI chr26:8,667,657...8,688,850
Ensembl chr26:8,667,655...8,688,824 		JBrowse link
G CSMD1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:2,806,358...4,821,568 JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:7,735,972...7,761,355
Ensembl chr26:7,694,014...7,761,342 		JBrowse link
G CSRNP1 cysteine and serine rich nuclear protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:262,329...274,003
Ensembl chr15:262,382...276,505 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility ISO DNA:SNPs: :rs231775,rs231725(human)
protein:increased expression:CD4+ and CD8+ T cells:		 RGD PMID:23432218 PMID:28648905 RGD:14398741 RGD:14398742 NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344 		JBrowse link
G CTNNB1 catenin beta 1 severity
exacerbates
susceptibility		 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA
DNA:Mutations:exon:
DNA:missense mutations:exon 3:multiple (human)
associated with hepatitis B;DNA:SNPs: :rs3864004,rs11564475(human)
associated with Hepatitis B, Chronic,DNA:SNP, haplotype: :rs3864004 (human)		 OMIM
ClinVar
RGD		 PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More... RGD:14402039 RGD:14402040 RGD:14402052 RGD:150429592 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CTSB cathepsin B ISO RGD PMID:15641152 RGD:2315605 NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854 		JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:1,570,163...1,581,857
Ensembl chr 1:1,570,069...1,581,833 		JBrowse link
G CTSL cathepsin L ISO RGD PMID:15641152 RGD:2315605 NCBI chr12:98,347,770...98,353,426
Ensembl chr12:98,347,800...98,353,467 		JBrowse link
G CUNH14orf180 chromosome unknown C14orf180 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr24:82,509,386...82,522,929
Ensembl chr24:82,513,692...82,522,935 		JBrowse link
G CUX1 cut like homeobox 1 ISO mRNA:increased expression:liver (human) RGD PMID:30561038 RGD:152985541 NCBI chr28:10,901,529...11,370,834
Ensembl chr28:10,937,512...11,370,702 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment
disease_progression		 ISO RGD PMID:27245433 PMID:28592115 PMID:28638480 RGD:27095889 RGD:27095898 RGD:27095899 NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr 7:24,540,401...24,543,456
Ensembl chr 7:24,541,767...24,542,832 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 9:40,005,580...40,020,513
Ensembl chr 9:40,011,439...40,020,494 		JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:38,355,340...38,363,905
Ensembl chr23:38,355,341...38,363,680 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 disease_progression
susceptibility		 ISO protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (human)
DNA:SNPs, haplotype:multiple		 RGD
CTD		 PMID:12432545 PMID:24381110 PMID:26078356 PMID:30523154 PMID:35776891 RGD:11526468 RGD:26884364 RGD:26884366 NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 severity
treatment		 ISO protein:increased expression:liver (human)
human cells in mouse model		 RGD PMID:30034941 PMID:33574707 RGD:151665327 RGD:151665331 NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21109933 NCBI chr 5:36,541,022...36,600,874
Ensembl chr 5:36,541,764...36,595,417 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:8,727,996...8,733,254 JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr14:35,030,011...35,057,164
Ensembl chr14:35,038,654...35,057,176 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 susceptibility ISO associated with hepatitis C; DNA:polymorphisms: : RGD PMID:11021356 RGD:124713413 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO DNA, mRNA:SNP, Decreased expression:liver: rs2031920 (human)
associated with alcohol dependence
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15162526 PMID:20364586 PMID:29765251 RGD:14700882 RGD:14700899 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:25,621,297...25,726,055
Ensembl chr17:25,621,305...25,728,617 		JBrowse link
G DAB2IP DAB2 interacting protein severity ISO protein:decreased expression:liver (human)
mRNA:decreased expression:liver (human)		 RGD PMID:22168621 PMID:31176165 RGD:151665110 RGD:151665148 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890 		JBrowse link
G DBH dopamine beta-hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:4,474,041...4,498,942
Ensembl chr12:4,474,958...4,498,910 		JBrowse link
G DCAF4L2 DDB1 and CUL4 associated factor 4 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:82,966,415...82,968,829 JBrowse link
G DCN decorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:86,552,392...86,590,229
Ensembl chr11:86,551,072...86,586,891 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 severity ISO mRNA:increased expression:liver (human) RGD PMID:33173221 RGD:151347691 NCBI chr17:41,564,271...41,583,404
Ensembl chr17:41,564,992...41,575,682 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 disease_progression
treatment		 ISO RGD PMID:26362312 PMID:33969575 RGD:11086753 RGD:150429748 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked exacerbates
sexual_dimorphism		 ISO associated with hepatitis B; mRNA,protein:decreased expression:liver (human) RGD PMID:16301996 PMID:30297359 RGD:151356499 RGD:151356660 NCBI chr  X:38,513,251...38,539,982
Ensembl chr  Y:689,380...706,092 		JBrowse link
G DEPDC1 DEP domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:64,615,693...64,639,088
Ensembl chr20:64,615,866...64,636,294 		JBrowse link
G DEPDC1B DEP domain containing 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:56,770,728...56,882,062
Ensembl chr 4:56,770,727...56,863,006 		JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21725309 NCBI chr19:14,634,836...14,798,050
Ensembl chr19:14,635,947...14,787,591 		JBrowse link
G DHFR dihydrofolate reductase ISO ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:28492532 NCBI chr 4:74,787,292...74,811,196
Ensembl chr 4:74,787,629...74,810,960 		JBrowse link
G DICER1 dicer 1, ribonuclease III susceptibility ISO associated with hepatitis B; DNA:SNP: :rs1057035 T>C (human) RGD PMID:23868705 RGD:149735346 NCBI chr24:72,915,550...72,986,658
Ensembl chr24:72,915,499...72,963,006 		JBrowse link
G DIPK2B divergent protein kinase domain 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:42,336,140...42,382,863 JBrowse link
G DIRAS3 DIRAS family GTPase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:65,060,391...65,065,165
Ensembl chr20:65,063,822...65,064,511 		JBrowse link
G DLGAP5 DLG associated protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr24:32,338,023...32,374,522 JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr24:78,687,542...78,695,782
Ensembl chr24:78,687,668...78,695,607 		JBrowse link
G DMGDH dimethylglycine dehydrogenase disease_progression ISO associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 4:73,217,523...73,339,646
Ensembl chr 4:73,216,579...73,290,268 		JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:67,661,187...67,824,822
Ensembl chr20:67,660,680...67,809,086 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:19,487,767...19,496,019
Ensembl chr22:19,487,596...19,496,129 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA, protein:increased expression:liver RGD PMID:11844796 RGD:2289670 NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO protein:increased expression:liver:
mRNA, protein:increased expression:liver		 RGD PMID:11844796 PMID:15885882 RGD:2289670 RGD:9588598 NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO mRNA, protein:increased expression:liver
mRNA:increased expression:liver:		 RGD PMID:11844796 PMID:15885882 RGD:2289670 RGD:9588598 NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18019677 NCBI chr20:35,376,738...36,215,388
Ensembl chr20:35,377,266...36,215,679 		JBrowse link
G DSN1 DSN1 component of MIS12 kinetochore complex disease_progression ISO RGD PMID:30136646 RGD:27372884 NCBI chr 2:57,511,171...57,525,241
Ensembl chr 2:57,511,366...57,527,088 		JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:17,418,078...17,485,320
Ensembl chr25:17,418,090...17,485,164 		JBrowse link
G DYNLRB1 dynein light chain roadblock-type 1 ISO RGD PMID:11750132 RGD:13208527 NCBI chr 2:38,813,852...38,839,905
Ensembl chr 2:38,825,574...38,839,903 		JBrowse link
G DYNLRB2 dynein light chain roadblock-type 2 ISO RGD PMID:11750132 RGD:13208527 NCBI chr 5:65,994,915...66,009,154
Ensembl chr 5:65,995,228...66,004,804 		JBrowse link
G E2F1 E2F transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12029619 PMID:15565109 PMID:28284560 NCBI chr 2:37,968,541...37,980,461
Ensembl chr 2:37,968,556...37,980,326 		JBrowse link
G E2F8 E2F transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:45,751,937...45,772,698
Ensembl chr 1:45,756,301...45,772,632 		JBrowse link
G EAF2 ELL associated factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20564326 NCBI chr22:58,966,640...59,025,158
Ensembl chr22:58,974,409...59,025,143 		JBrowse link
G ECM1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560
G ECT2 epithelial cell transforming 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:16,612,738...16,685,455
Ensembl chr15:16,612,443...16,685,386 		JBrowse link
G EEF2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression, increased phosphorylation:liver (human) RGD PMID:28060762 RGD:153298915 NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 disease_progression ISO protein:decreased expression:liver: RGD PMID:23936443 RGD:10401793 NCBI chr14:50,989,553...51,048,149
Ensembl chr14:50,989,795...51,048,708 		JBrowse link
G EFTUD2 elongation factor Tu GTP binding domain containing 2 severity
ameliorates		 ISO RGD PMID:34282556 RGD:155791664 NCBI chr16:61,505,796...61,549,720
Ensembl chr16:61,505,825...61,551,890 		JBrowse link
G EGF epidermal growth factor susceptibility ISO associated with liver cirrhosis;DNA:SNP:5'UTR: (rs4444903) (human)
CTD Direct Evidence: marker/mechanism
associated with hepatitis B;DNA:SNP:exon: (rs11569017) (human)		 RGD
CTD		 PMID:9029167 PMID:18167406 PMID:23790025 RGD:14695013 RGD:14695014 NCBI chr 7:57,810,110...57,911,361
Ensembl chr 7:57,811,728...57,911,516 		JBrowse link
G EGFR epidermal growth factor receptor disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:9029167 PMID:11355950 RGD:126781769 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G EGR1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374 		JBrowse link
G EGR2 early growth response 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:68,472,640...68,479,612
Ensembl chr 9:68,475,102...68,479,595 		JBrowse link
G EHD3 EH domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:76,237,345...76,271,557
Ensembl chr14:76,236,246...76,271,546 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H ISO CTD Direct Evidence: marker/mechanism CTD PMID:14578863 NCBI chr 8:111,283,184...111,390,835 JBrowse link
G ENAH ENAH actin regulator disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35030977 RGD:155791678 NCBI chr25:4,134,853...4,264,392
Ensembl chr25:4,134,852...4,260,928 		JBrowse link
G ENG endoglin ISO protein:increased expression:liver (rat) RGD PMID:20368095 RGD:7257538 NCBI chr12:10,274,705...10,315,715
Ensembl chr12:10,275,064...10,315,040 		JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr20:122,884,846...122,902,669
Ensembl chr20:122,884,727...122,903,372 		JBrowse link
G EP300 E1A binding protein p300 ISO protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26735578 NCBI chr14:60,823,110...60,912,804
Ensembl chr14:60,822,815...60,912,785 		JBrowse link
G EPCAM epithelial cell adhesion molecule severity ISO protein:increased expression:liver RGD PMID:24616575 RGD:14695007 NCBI chr14:59,815,128...59,832,360
Ensembl chr14:59,815,064...59,832,229 		JBrowse link
G EPHB1 EPH receptor B1 ISO protein:increased phosphorylation:liver (mouse) RGD PMID:28100771 RGD:127285675 NCBI chr15:55,144,178...55,592,252
Ensembl chr15:55,143,630...55,589,862 		JBrowse link
G EPHX1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7892276 NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535 		JBrowse link
G EPO erythropoietin disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr28:12,487,222...12,491,986
Ensembl chr28:12,489,766...12,491,908 		JBrowse link
G EPS8L3 EPS8 signaling adaptor L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:23,780,116...23,795,946
Ensembl chr20:23,781,999...23,795,989 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:11355950 RGD:126781769 NCBI chr11:52,020,912...52,043,809
Ensembl chr11:52,021,058...52,044,028 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO DNA:insertion/deletion:3'UTR:rs6147150 (human) RGD PMID:22294845 RGD:126781763 NCBI chr10:97,099,090...98,281,697 JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO mRNA, protein:increased expression:liver (human) RGD PMID:15922480 RGD:155598683 NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility
disease_progression		 ISO DNA:SNPs:exon 23: p.K751Q (human)
DNA:SNP:cd: 312A>G (human)
DNA:SNPs:exon 23: p.K751Q (human)
DNA:SNPs:exon 23: p.K751Q (rs13181) (human)		 RGD PMID:19919686 PMID:25531380 PMID:28598207 PMID:28927037 RGD:150530503 RGD:25671459 RGD:25671460 RGD:25671461 NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073 		JBrowse link
G EREG epiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:35776891 NCBI chr 7:22,898,998...22,924,922
Ensembl chr 7:22,901,862...22,920,678 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO DNA:hypomethylation: CpG islands: RGD PMID:20165882 RGD:14694974 NCBI chr16:57,145,080...57,233,757
Ensembl chr16:57,145,191...57,236,230 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499 		JBrowse link
G ESM1 endothelial cell specific molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:51,227,908...51,269,280
Ensembl chr 4:51,227,916...51,235,972 		JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G ETFA electron transfer flavoprotein subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr26:6,970,593...7,075,077
Ensembl chr26:6,970,584...7,076,049 		JBrowse link
G EXO1 exonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:78,934,337...78,976,346
Ensembl chr25:78,934,459...78,976,219 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility ISO mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple		 RGD
CTD		 PMID:24040354 PMID:24211739 PMID:25226601 PMID:26517514 PMID:28284560 More... RGD:10755339 RGD:11537550 RGD:126779595 RGD:126779608 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G FABP5 fatty acid binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 8:76,696,899...76,701,459 JBrowse link
G FAM180A family with sequence similarity 180 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:104,411,934...104,428,708
Ensembl chr21:104,412,351...104,427,540 		JBrowse link
G FAM83D family with sequence similarity 83 member D ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:24,800,558...24,828,048 JBrowse link
G FANCD2 FA complementation group D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:46,072,797...46,141,107
Ensembl chr22:46,072,761...46,140,713 		JBrowse link
G FANCI FA complementation group I ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr29:7,788,983...7,864,505
Ensembl chr29:7,790,458...7,855,552 		JBrowse link
G FASLG Fas ligand ISO protein:increased expression:liver: RGD PMID:11274632 RGD:14700677 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251 		JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 PMID:15543204 PMID:21147110 NCBI chr16:73,988,410...74,008,374
Ensembl chr16:73,982,899...74,006,551 		JBrowse link
G FAT1 FAT atypical cadherin 1 disease_progression ISO mRNA,protein:increased expression:liver (human) RGD PMID:24590895 RGD:151347630 NCBI chr 7:132,475,689...132,616,151
Ensembl chr 7:132,483,032...132,616,112 		JBrowse link
G FATE1 fetal and adult testis expressed 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15580283 NCBI chr  X:126,269,120...126,275,053
Ensembl chr  X:126,269,555...126,275,052 		JBrowse link
G FBP1 fructose-bisphosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22039417 NCBI chr12:108,452,856...108,484,052
Ensembl chr12:108,453,156...108,483,775 		JBrowse link
G FBXL18 F-box and leucine rich repeat protein 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr28:16,216,102...16,249,262
Ensembl chr28:16,216,176...16,248,409 		JBrowse link
G FBXO11 F-box protein 11 exacerbates
ameliorates		 ISO mRNA:increased expression:liver (human)
protein:increased expression:liver (human)		 RGD PMID:29518611 PMID:29603830 PMID:32657545 RGD:152025259 RGD:152025263 RGD:152025266 NCBI chr14:59,276,380...59,375,635
Ensembl chr14:59,276,447...59,374,442 		JBrowse link
G FCN2 ficolin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:3,255,810...3,264,561 JBrowse link
G FCN3 ficolin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:105,414,626...105,420,684
Ensembl chr20:105,414,650...105,420,558 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 8:7,272,580...7,306,859
Ensembl chr 8:7,271,509...7,306,760 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase exacerbates ISO DNA:hypermethylation:promoter (human) RGD PMID:31038805 RGD:153323297 NCBI chr29:8,967,542...8,979,475
Ensembl chr29:8,965,997...8,979,361 		JBrowse link
G FGF19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 1:4,852,289...4,860,139
Ensembl chr 1:4,854,363...4,859,102 		JBrowse link
G FGF3 fibroblast growth factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 1:4,746,195...4,755,654
Ensembl chr 1:4,746,696...4,754,924 		JBrowse link
G FGF4 fibroblast growth factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 1:4,786,296...4,791,441
Ensembl chr 1:4,789,203...4,791,036 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 treatment ISO ClinVar Annotator: match by term: Hepatocellular carcinoma RGD
ClinVar		 PMID:21573021 PMID:25705862 PMID:26619011 PMID:26942290 PMID:33448156 RGD:25440476 NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 severity ISO associated with hepatitis B;DNA:SNPs: promoter, intron:rs308379, rs1219648 (human) RGD PMID:30952770 RGD:38501096 NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 treatment ISO RGD PMID:32677805 RGD:150520166 NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456 		JBrowse link
G FH fumarate hydratase ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:10896297 PMID:15221078 PMID:16876016 PMID:17182618 PMID:18313410 More... NCBI chr25:78,576,931...78,599,998
Ensembl chr25:78,575,300...78,599,972 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO RGD PMID:12112319 RGD:632723 NCBI chr22:21,006,010...22,474,056 JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ameliorates ISO human cells in mouse model RGD PMID:27511526 RGD:149735514 NCBI chr 3:7,117,579...7,222,600
Ensembl chr 3:7,116,947...7,222,849 		JBrowse link
G FLVCR1 FLVCR choline and heme transporter 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:16,656,219...16,688,397
Ensembl chr25:16,652,246...16,688,376 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:9029167 PMID:28284560 NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:38,916,039...38,924,129 JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO mRNA:increased expression:liver (human) RGD PMID:30086463 PMID:32048611 RGD:153344517 RGD:153344521 NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373 		JBrowse link
G FOXA1 forkhead box A1 disease_progression
sexual_dimorphism
susceptibility		 ISO protein:decreased expression:liver
DNA:VNTR, SNPs, haplotypes:multiple:		 RGD PMID:25965836 PMID:29208003 PMID:31400761 RGD:11054501 RGD:151665752 RGD:151665820 NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094 		JBrowse link
G FOXM1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:15082532 PMID:17173139 PMID:28284560 NCBI chr11:2,920,903...2,941,011
Ensembl chr11:2,920,663...2,940,823 		JBrowse link
G FOXO1 forkhead box O1 ISO mRNA:decreased expression:liver RGD PMID:28972178 RGD:14401599 NCBI chr 3:18,916,849...19,027,776
Ensembl chr 3:18,920,651...19,027,707 		JBrowse link
G FOXP1 forkhead box P1 treatment ISO RGD PMID:25156538 RGD:9587823 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502 		JBrowse link
G FOXP3 forkhead box P3 ISO protein:increased expression:liver RGD PMID:21086571 RGD:38548919 NCBI chr  X:46,349,890...46,365,133 JBrowse link
G FST follistatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203361 PMID:19363144 NCBI chr 4:49,773,646...49,780,343
Ensembl chr 4:49,773,980...49,780,333 		JBrowse link
G FTH1 ferritin heavy chain 1 ISO mRNA:increased expression:liver (rat) RGD PMID:9054589 RGD:632698 NCBI chr 1:11,837,533...11,840,926 JBrowse link
G FUBP1 far upstream element binding protein 1 exacerbates
ameliorates		 ISO mRNA:increased expression:liver (human)
associated with Chronic Hepatitis C;mRNA:increased expression:liver (human)
human cell line in a mouse model 		RGD PMID:19637194 PMID:25995247 PMID:31587040 RGD:151361188 RGD:151361194 RGD:151361196 NCBI chr20:55,194,681...55,233,666
Ensembl chr20:55,194,743...55,230,277 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 treatment ISO associated with Glycogen Storage Disease IA, human gene in a mouse model RGD PMID:28096054 RGD:14695537 NCBI chr16:63,380,921...63,392,122
Ensembl chr16:63,381,382...63,391,540 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:25473368 PMID:35693827 RGD:10449118 RGD:153344586 NCBI chr  X:128,768,028...128,788,366
Ensembl chr  X:128,770,268...128,786,961 		JBrowse link
G GABRD gamma-aminobutyric acid type A receptor subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:129,530,049...129,541,437
Ensembl chr20:129,529,108...129,541,580 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16767786 PMID:21472284 NCBI chr11:6,569,029...6,572,877 JBrowse link
G GC GC vitamin D binding protein susceptibility ISO associated with Hepatitis B, Chronic;DNA:SNP: :rs7041(human)
protein:increased expression:liver		 RGD PMID:21683810 PMID:25541958 RGD:14402025 RGD:5509919 NCBI chr 7:20,254,604...20,298,384
Ensembl chr 7:20,253,879...20,298,265 		JBrowse link
G GDF15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20512989 NCBI chr 6:16,853,397...16,861,924
Ensembl chr 6:16,852,971...16,861,964 		JBrowse link
G GDF2 growth differentiation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23936038 PMID:28284560 NCBI chr 9:44,087,502...44,092,975
Ensembl chr 9:44,089,358...44,092,484 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 disease_progression ISO RNA,protein:increased expression, activity:liver:
HBV associated		 RGD PMID:10572675 PMID:11940314 PMID:27793641 RGD:14701040 RGD:14701041 RGD:14701048
G GHR growth hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666 		JBrowse link
G GJB1 gap junction protein beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17978847 NCBI chr  X:61,013,991...61,019,222
Ensembl chr  X:61,017,716...61,018,567 		JBrowse link
G GJB2 gap junction protein beta 2 ISO DNA, mRNA:promoter hypermethylation, decreased expression:liver RGD PMID:17295234 RGD:2289638 NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059 		JBrowse link
G GLI1 GLI family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr11:53,371,929...53,384,339
Ensembl chr11:53,375,558...53,385,269 		JBrowse link
G GLUL glutamate-ammonia ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr25:46,988,853...46,998,112
Ensembl chr25:46,989,205...47,000,555 		JBrowse link
G GMNN geminin DNA replication inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:47,462,647...47,474,445
Ensembl chr17:47,461,645...47,474,417 		JBrowse link
G GMPS guanine monophosphate synthase ISO protein:increased activity:hepatoma (rat) RGD PMID:6861338 RGD:5135537 NCBI chr15:34,817,603...34,885,363
Ensembl chr15:34,815,066...34,885,228 		JBrowse link
G GNAO1 G protein subunit alpha o1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:42,105,295...42,272,573
Ensembl chr 5:42,105,334...42,273,059 		JBrowse link
G GNAZ G protein subunit alpha z ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:2,758,097...2,812,306
Ensembl chr19:2,757,819...2,788,076 		JBrowse link
G GNMT glycine N-methyltransferase ISO CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:19146867 PMID:31086990 NCBI chr17:29,196,142...29,199,728
Ensembl chr17:29,196,321...29,198,947 		JBrowse link
G GOLM1 golgi membrane protein 1 severity ISO protein:increased expression:serum
mRNA, protein:increased expression:liver		 RGD PMID:21140449 PMID:21443671 RGD:401827118 RGD:401827119 NCBI chr12:96,706,865...96,778,687
Ensembl chr12:96,708,548...96,779,065 		JBrowse link
G GPC1 glypican 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr10:126,464,383...126,496,686
Ensembl chr10:126,464,801...126,497,897 		JBrowse link
G GPC3 glypican 3 severity
exacerbates
disease_progression
treatment		 ISO protein:increased expression:liver
protein:increased expression:liver (human)
protein:increased expression:blood serum (human)
mRNA,protein:increased expression:peripheral blood mononuclear cell,blood serum, liver (human)
mRNA:increased expression:Peripheral Blood (human)
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16698587 PMID:19496787 PMID:21438004 PMID:22883669 PMID:23558072 More... RGD:14695019 RGD:14695020 RGD:243065125 RGD:243065131 RGD:243065134 RGD:243065135 RGD:243065139 NCBI chr  X:108,688,706...109,143,653 JBrowse link
G GPM6A glycoprotein M6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:121,715,329...122,082,175
Ensembl chr 7:121,714,770...121,894,739 		JBrowse link
G GPR158 G protein-coupled receptor 158 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:24,903,263...25,310,817 JBrowse link
G GPR182 G protein-coupled receptor 182 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:52,904,691...52,908,786
Ensembl chr11:52,905,582...52,906,796 		JBrowse link
G GPX1 glutathione peroxidase 1 severity
no_association
susceptibility		 ISO associated with hepatitis C;DNA:missense mutation:CDS:p.P198L (rs1050450) (human)
DNA:missense mutation:CDS:p.P198L (human)
associated with alcoholic liver cirrhosis;DNA:missense mutation:CDS:p.P198L (human)		 RGD PMID:16510607 PMID:19929244 PMID:25894370 PMID:26990426 RGD:11533013 RGD:151708729 RGD:152995483 RGD:152998906 NCBI chr22:10,754,976...10,756,617 JBrowse link
G GPX3 glutathione peroxidase 3 severity
disease_progression		 ISO mRNA,protein:decreased expression:liver, blood plasma (human)
DNA:hypermethylation		 RGD PMID:25333265 PMID:25445749 PMID:27570561 RGD:151665355 RGD:151665509 RGD:401827855 NCBI chr23:53,576,950...53,585,321 JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates ISO protein:increased expression:liver (human) RGD PMID:17634422 RGD:151347655 NCBI chr16:66,416,978...66,427,035
Ensembl chr16:66,416,904...66,426,300 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism
DNA:increased methylation:promoter		 CTD
RGD		 PMID:9029167 PMID:22536438 RGD:14401712 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G GTSE1 G2 and S-phase expressed 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:28,776,515...28,811,712
Ensembl chr19:28,777,821...28,811,035 		JBrowse link
G GYS2 glycogen synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:21,400,582...21,464,438
Ensembl chr11:21,398,869...21,463,277 		JBrowse link
G HAMP hepcidin antimicrobial peptide ISO mRNA:decreased expression:liver (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:28284560 PMID:29235098 RGD:15042879 NCBI chr 6:30,214,820...30,218,100
Ensembl chr 6:30,215,563...30,217,996 		JBrowse link
G HAO2 hydroxyacid oxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:14,376,096...14,408,753
Ensembl chr20:14,374,543...14,407,992 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr23:59,422,769...59,454,183
Ensembl chr23:59,423,334...59,453,531 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 disease_progression ISO associated with hepatitis B;DNA:SNP: : ���1516 G>T (human) RGD PMID:27034168 RGD:40818257 NCBI chr23:59,479,794...59,501,532
Ensembl chr23:59,475,826...59,500,836 		JBrowse link
G HDAC2 histone deacetylase 2 disease_progression ISO mRNA:increased expression:liver: RGD PMID:24448241 RGD:9590206 NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742 		JBrowse link
G HDAC4 histone deacetylase 4 ISO mRNA:increased expression:liver: RGD PMID:21837748 RGD:9681451 NCBI chr10:125,098,375...125,450,524
Ensembl chr10:125,098,366...125,403,227 		JBrowse link
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28919514 NCBI chr 7:36,817,118...36,867,712
Ensembl chr 7:36,819,708...36,867,933 		JBrowse link
G HFE homeostatic iron regulator disease_progression ISO associated with Liver Cirrhosis;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:20019189 PMID:29642405 RGD:14746967 RGD:2317357 NCBI chr17:46,159,770...46,168,831
Ensembl chr17:46,156,685...46,164,649 		JBrowse link
G HGF hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9932610 PMID:11896611 NCBI chr21:67,118,785...67,193,506
Ensembl chr21:67,120,722...67,193,504 		JBrowse link
G HGFAC HGF activator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr27:45,283,213...45,290,922
Ensembl chr27:45,283,206...45,290,644 		JBrowse link
G HHIP hedgehog interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18559595 NCBI chr 7:91,216,874...91,311,392
Ensembl chr 7:91,216,955...91,310,387 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha disease_progression
treatment		 ISO protein:increased expression:liver (human) RGD PMID:19335982 PMID:26078356 PMID:31321740 RGD:11526468 RGD:155882550 RGD:9068886 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated disease_progression ISO mRNA:increased expression:liver (human)
human cells in mouse model
mRNA, protein:increased expression:liver (human)		 RGD PMID:30205391 PMID:31142329 PMID:35693827 RGD:153344574 RGD:153344577 RGD:153344586 NCBI chr21:97,254,246...97,257,186 JBrowse link
G HJURP Holliday junction recognition protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:119,857,118...119,885,945
Ensembl chr10:119,868,303...119,885,783 		JBrowse link
G HMGB2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20851854 NCBI chr 7:119,440,089...119,442,806
Ensembl chr 7:119,440,468...119,443,578 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9207284 PMID:21147110 NCBI chr 4:69,664,784...69,690,343
Ensembl chr 4:69,665,417...69,688,686 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 disease_progression ISO RGD PMID:28867541 RGD:14975299 NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016 		JBrowse link
G HNF1A HNF1 homeobox A treatment ISO human cell line in mouse model RGD PMID:29466992 RGD:14700664 NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO protein:decreased expression:liver: RGD PMID:20876809 RGD:12904747 NCBI chr 2:19,390,870...19,466,300
Ensembl chr 2:19,388,891...19,421,664 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr11:50,397,173...50,403,192
Ensembl chr11:50,396,888...50,400,802 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO protein:increased expression:liver (human)
mRNA:increased expression:liver (rat)		 RGD PMID:20604928 PMID:23633480 RGD:9685422 RGD:9685423 NCBI chr21:32,167,126...32,178,031
Ensembl chr21:32,167,337...32,176,980 		JBrowse link
G HNRNPAB heterogeneous nuclear ribonucleoprotein A/B severity ISO mRNA:increased expression:liver (human) RGD PMID:24638979 RGD:10059322 NCBI chr23:79,891,942...79,903,289 JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D ISO protein:increased expression:liver (human)
protein:increased expression:liver (rat)		 RGD PMID:20102719 PMID:22318685 RGD:10042969 RGD:10042977 NCBI chr 7:30,729,697...30,749,793
Ensembl chr 7:30,731,175...30,749,876 		JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 ISO protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr23:81,330,777...81,340,470
Ensembl chr23:81,330,351...81,339,882 		JBrowse link
G HNRNPL heterogeneous nuclear ribonucleoprotein L ISO associated with Hepatitis B RGD PMID:24125732 RGD:9999429 NCBI chr 6:33,452,705...33,469,070
Ensembl chr 6:33,452,852...33,466,284 		JBrowse link
G HOXA10 homeobox A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:31,189,240...31,198,244 JBrowse link
G HOXA13 homeobox A13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:31,168,239...31,175,960
Ensembl chr21:31,168,793...31,173,056 		JBrowse link
G HOXD9 homeobox D9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:61,695,065...61,699,936
Ensembl chr10:61,697,271...61,699,933 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr  X:109,629,674...109,671,409 JBrowse link
G HRAS HRas proto-oncogene, GTPase treatment ISO human cells in a mouse model
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma		 RGD
ClinVar		 PMID:10791191 PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 More... RGD:14688055 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 PMID:29698666 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr23:41,230,675...41,251,177
Ensembl chr23:41,231,364...41,251,150 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr28:10,442,530...10,443,804
Ensembl chr28:10,442,398...10,443,855 		JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:16799960 NCBI chr 1:44,624,782...44,643,188
Ensembl chr 1:44,624,734...44,643,121 		JBrowse link
G HTRA1 HtrA serine peptidase 1 disease_progression
exacerbates		 ISO mRNA:decreased expression:liver (human)
protein:decreased expression:liver (human)		 RGD PMID:20943460 PMID:26403966 RGD:152985524 RGD:152985529 NCBI chr 9:115,197,543...115,250,092
Ensembl chr 9:115,197,566...115,253,919 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 severity ISO protein:increased expression:serum RGD PMID:26109813 RGD:11056752 NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975 		JBrowse link
G IER2 immediate early response 2 ISO mRNA, protein:decreased expression:liver (human) RGD PMID:32009420 RGD:153323326 NCBI chr 6:11,834,998...11,838,421
Ensembl chr 6:11,836,706...11,837,377 		JBrowse link
G IFNA2 interferon alpha 2 susceptibility ISO associated with hepatitis B; DNA:SNP:enhancer: (rs649053) (human) RGD PMID:29080269 RGD:21406429 NCBI chr12:58,468,018...58,469,825 JBrowse link
G IFNG interferon gamma ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473 		JBrowse link
G IGBP1 immunoglobulin binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21339737 NCBI chr  X:59,970,740...60,008,066
Ensembl chr  X:59,971,234...60,008,047 		JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G IGF1R insulin like growth factor 1 receptor susceptibility ISO DNA:SNPs, haplotype: :
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17441810 PMID:23958494 PMID:24758241 RGD:14985227 NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930 		JBrowse link
G IGF2 insulin like growth factor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with hepatitis B;DNA:SNPs:intron, 3'utr:+2482A>C, +820A>G (human)		 RGD
CTD		 PMID:12532445 PMID:16092956 PMID:16750516 PMID:17554210 RGD:14401723 RGD:2311523 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:69,405,923...69,461,613
Ensembl chr16:69,406,549...69,459,175 		JBrowse link
G IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:34,846,383...34,999,579
Ensembl chr21:34,954,129...34,997,439 		JBrowse link
G IGF2R insulin like growth factor 2 receptor treatment
no_association
disease_progression		 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:loss of heterozygosity,mutations:liver:
DNA:loss of heterozygosity:liver		 OMIM
ClinVar
RGD		 PMID:9722161 PMID:10347113 PMID:18322954 PMID:25741868 PMID:30720132 RGD:14985219 RGD:14985220 RGD:14985221 NCBI chr13:87,587,717...87,723,795
Ensembl chr13:87,587,907...87,724,116 		JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:1,698,787...1,704,205
Ensembl chr 5:1,698,978...1,701,972 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment ISO protein:decreased expression:liver (human) RGD PMID:17292824 PMID:22176836 PMID:22922425 PMID:24971483 PMID:25173965 More... RGD:11079569 RGD:153297807 RGD:153297813 RGD:153305943 RGD:153305945 RGD:153305947 NCBI chr  X:128,781,975...128,816,039
Ensembl chr  X:128,787,785...128,806,083 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 ameliorates ISO protein:increased expression:liver (human) RGD PMID:25301737 RGD:150540326 NCBI chr21:8,398,902...8,500,431
Ensembl chr21:8,402,719...8,484,723 		JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23822114 PMID:26890368 RGD:14975171 RGD:7365006 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836 		JBrowse link
G IL12A interleukin 12A susceptibility ISO DNA:SNP:3'UTR: rs568408( G>A)(human)
associated with hepatitis C;DNA:SNP:3'UTR: rs568408( G>A)(human)
associated with hepatitis B; DNA:SNP, haplotype:3′UTR :rs568408(human)		 RGD PMID:20521253 PMID:26631030 PMID:27819525 RGD:25440490 RGD:25440491 RGD:25440501 NCBI chr15:30,887,048...30,896,577
Ensembl chr15:30,887,897...30,894,550 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 9:6,061,475...6,096,370
Ensembl chr 9:6,061,197...6,096,250 		JBrowse link
G IL18 interleukin 18 disease_progression
susceptibility
severity		 ISO DNA:SNP:promoter:-137G>C(rs187238)(human)
associated with hepatitis B, chronic;DNA:SNP:promoter:-607C>A(human)
associated with hepatitis C;DNA:SNPs, haplotype:promoter:-607C>A, -137G>C(human)		 RGD PMID:26893476 PMID:27429592 PMID:27470888 PMID:29341496 RGD:11538094 RGD:14695526 RGD:14695540 RGD:14696663 NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150 		JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO mRNA:decreased expression:liver RGD PMID:26893476 RGD:11538094 NCBI chr14:6,026,683...6,067,808
Ensembl chr14:6,026,443...6,066,884 		JBrowse link
G IL1B interleukin 1 beta susceptibility ISO DNA:polymorphism:promoter:-31T>C (human) RGD PMID:21653279 RGD:7401222 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729 		JBrowse link
G IL1RAP interleukin 1 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:84,728,594...84,876,098
Ensembl chr15:84,728,517...84,866,263 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326 		JBrowse link
G IL2 interleukin 2 treatment ISO RGD PMID:9449371 PMID:10933975 RGD:14747035 RGD:8693323 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969 		JBrowse link
G IL21 interleukin 21 ISO associated with hepatitis B;DNA:SNPS, haplotype:(rs13143866, rs2221903, rs907715) (human) RGD PMID:25892873 RGD:127285359 NCBI chr 7:69,859,793...69,872,237
Ensembl chr 7:69,863,535...69,872,025 		JBrowse link
G IL6 interleukin 6 disease_progression
treatment		 ISO mRNA,protein:increased expression:liver, blood serum (mouse)
DNA:SNP: :rs2069852 (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17615358 PMID:20818158 PMID:26297436 PMID:26569409 PMID:27022031 More... RGD:11344640 RGD:127285672 RGD:14975289 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer ISO RGD PMID:15780071 RGD:1626706 NCBI chr 4:52,174,893...52,232,475
Ensembl chr 4:52,174,312...52,214,584 		JBrowse link
G ING3 inhibitor of growth family member 3 treatment ISO RGD PMID:25156538 RGD:9587823 NCBI chr21:89,772,546...89,802,250
Ensembl chr21:89,772,528...89,802,244 		JBrowse link
G INMT indolethylamine N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:27,635,727...27,707,463
Ensembl chr21:27,634,903...27,639,800 		JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 7:88,929,249...89,732,375
Ensembl chr 7:88,979,493...89,461,475 		JBrowse link
G INS insulin ISO associated with Chronic Hepatitis C;mRNA:decreased expression:liver (human) RGD PMID:33132693 RGD:150340613 NCBI chr 1:1,965,128...1,969,090 JBrowse link
G INSR insulin receptor ISO mRNA, protein:increased expression:liver (human, rat)
human cells in a mouse model		 RGD PMID:23633480 PMID:29610518 RGD:14700930 RGD:9685423 NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20977743 NCBI chr29:9,363,273...9,485,644
Ensembl chr29:9,362,926...9,485,526 		JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 ISO CTD Direct Evidence: marker/mechanism
OMIM:114550		 CTD
MouseDO		 PMID:20977743 NCBI chr 4:70,672,171...70,979,766
Ensembl chr 4:70,672,553...70,979,763 		JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:7,286,819...7,334,352
Ensembl chr20:7,286,886...7,333,284 		JBrowse link
G IRF2 interferon regulatory factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr 7:130,352,809...130,440,485
Ensembl chr 7:130,350,262...130,440,600 		JBrowse link
G IRS1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1311924 PMID:23958494 NCBI chr10:112,748,283...112,812,368 JBrowse link
G IRS2 insulin receptor substrate 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16127164 NCBI chr 3:88,045,439...88,076,468 JBrowse link
G ISG15 ISG15 ubiquitin like modifier ISO CTD Direct Evidence: marker/mechanism CTD PMID:28919514 NCBI chr20:130,419,909...130,421,409
Ensembl chr20:130,419,782...130,421,380 		JBrowse link
G ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr22:14,176,656...14,191,256
Ensembl chr22:14,177,334...14,191,353 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 disease_progression ISO associated with hepatitis B;protein:decreased expression:serum RGD PMID:24836184 RGD:40903002 NCBI chr22:14,194,979...14,216,180
Ensembl chr22:14,195,701...14,213,603 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO protein:increased expression:liver RGD PMID:30660174 RGD:14694832 NCBI chr 2:27,484,699...27,521,108
Ensembl chr 2:27,484,760...27,522,504 		JBrowse link
G JAK1 Janus kinase 1 ISO RGD PMID:23788652 RGD:150524353 NCBI chr20:68,122,134...68,253,361
Ensembl chr20:68,122,173...68,252,042 		JBrowse link
G JAK2 Janus kinase 2 severity
treatment
exacerbates
ameliorates		 ISO protein:increased phosphorylation:liver (mouse)
mRNA:decreased expression:liver (human)
protein:increased phosphorylation:liver (human)
L-JAK2 KO
associated with Diseases of the Aged and non-alcoholic fatty liver disease		 RGD PMID:22392353 PMID:22821478 PMID:25420511 PMID:28100771 PMID:29486150 More... RGD:125097525 RGD:127285621 RGD:127285655 RGD:127285672 RGD:127285675 RGD:18182928 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G JDP2 Jun dimerization protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr24:52,668,837...52,702,257
Ensembl chr24:52,669,162...52,702,521 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO associated with HBV;protein:increased expression:liver (human) RGD PMID:15927205 RGD:153297768 NCBI chr 6:16,754,553...16,756,458
Ensembl chr 6:16,755,247...16,756,290 		JBrowse link
G KAT2B lysine acetyltransferase 2B severity ISO protein:decreased expression:liver (human) RGD PMID:23643089 RGD:9590314 NCBI chr15:64,769,590...64,885,536
Ensembl chr15:64,770,185...64,886,219 		JBrowse link
G KBTBD11 kelch repeat and BTB domain containing 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:1,634,347...1,661,024
Ensembl chr 8:1,661,172...1,663,043 		JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 ISO protein:increased expression:liver (human) RGD PMID:17022810 RGD:9693723 NCBI chr25:18,353,356...18,788,472
Ensembl chr25:18,353,482...18,783,592 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:17,595,661...17,735,675
Ensembl chr23:17,598,177...17,735,669 		JBrowse link
G KDM1A lysine demethylase 1A severity ISO mRNA, protein:increased expression:liver (human) RGD PMID:23236241 RGD:9681002 NCBI chr20:109,592,761...109,657,885
Ensembl chr20:109,593,074...109,657,839 		JBrowse link
G KDM3A lysine demethylase 3A ISO mRNA:increased expression:liver (human) RGD PMID:21607773 RGD:9590222 NCBI chr14:20,668,215...20,721,854
Ensembl chr14:20,668,821...20,720,759 		JBrowse link
G KDM5C lysine demethylase 5C exacerbates ISO protein:increased expression:liver (human) RGD PMID:26503415 RGD:11530160 NCBI chr  X:49,306,472...49,356,151
Ensembl chr  X:49,321,173...49,356,100 		JBrowse link
G KDM6A lysine demethylase 6A ameliorates ISO human cells in a mouse model RGD PMID:32765772 RGD:150429729 NCBI chr  X:42,053,272...42,291,013
Ensembl chr  X:42,053,336...42,290,526 		JBrowse link
G KDM8 lysine demethylase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:24,907,345...24,927,028
Ensembl chr 5:24,907,657...24,928,995 		JBrowse link
G KDR kinase insert domain receptor treatment
disease_progression		 ISO DNA:SNPs: :rs1870377, rs2071559, rs2305948 (human)
associated with alcoholic liver cirrhosis;DNA:SNP: :1416A>T (human)
protein:decreased expression:liver
protein:increased expression:liver		 RGD PMID:19177438 PMID:23660204 PMID:24445728 PMID:25182707 PMID:25333267 RGD:126848806 RGD:126848810 RGD:126848812 RGD:126848813 RGD:126848814 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
G KIF11 kinesin family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:85,858,364...85,923,211
Ensembl chr 9:85,858,381...85,923,819 		JBrowse link
G KIF14 kinesin family member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:28,789,952...28,856,713
Ensembl chr25:28,789,614...28,856,570 		JBrowse link
G KIF15 kinesin family member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:6,238,804...6,325,804
Ensembl chr22:6,249,567...6,325,510 		JBrowse link
G KIF18A kinesin family member 18A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:37,003,325...37,088,705
Ensembl chr 1:37,003,357...37,088,640 		JBrowse link
G KIF18B kinesin family member 18B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:61,455,785...61,478,232
Ensembl chr16:61,456,467...61,478,002 		JBrowse link
G KIF1B kinesin family member 1B susceptibility
severity		 ISO DNA:snp:intron:c.2537+518A>G (rs17401966) (human)
mRNA, protein:decreased expression:liver (human)		 RGD PMID:26217094 PMID:27122668 RGD:11052488 RGD:12738461 NCBI chr20:121,393,478...121,567,704
Ensembl chr20:121,395,836...121,546,803 		JBrowse link
G KIF20A kinesin family member 20A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:40,848,762...40,857,685
Ensembl chr23:40,849,108...40,857,434 		JBrowse link
G KIF23 kinesin family member 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:14,008,717...14,044,272
Ensembl chr26:14,008,633...14,043,710 		JBrowse link
G KIF2C kinesin family member 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:88,023,250...88,054,715
Ensembl chr20:88,023,207...88,055,176 		JBrowse link
G KIF4A kinesin family member 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:60,135,371...60,266,301 JBrowse link
G KIFC1 kinesin family member C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:38,656,517...38,675,056
Ensembl chr17:38,656,246...38,674,470 		JBrowse link
G KLF4 KLF transcription factor 4 treatment
disease_progression		 ISO RGD PMID:22677193 RGD:14402023 NCBI chr12:32,045,690...32,050,531
Ensembl chr12:32,045,609...32,050,703 		JBrowse link
G KLRF1 killer cell lectin like receptor F1 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr11:9,715,900...9,731,454
Ensembl chr11:9,716,010...9,731,387 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 1:109,819,748...109,912,763
Ensembl chr 1:109,853,758...109,908,113 		JBrowse link
G KMT2B lysine methyltransferase 2B ISO CTD Direct Evidence: marker/mechanism
DNA:insertions, translocations:intron:IVS3, multiple (human)		 CTD
RGD		 PMID:18320596 PMID:22634754 RGD:9588597 NCBI chr 6:30,626,723...30,648,204
Ensembl chr 6:30,626,848...30,647,883 		JBrowse link
G KMT2C lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr21:120,299,295...120,587,843
Ensembl chr21:120,301,188...120,587,137 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase induced ISO aflatoxin B1 induced:DNA:transversion,transition mutations:cds:
ClinVar Annotator: match by term: Hepatocellular cancer		 RGD
ClinVar		 PMID:2278970 PMID:3122217 PMID:8446626 PMID:12460918 PMID:15696205 More... RGD:11568697 NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G KRT18 keratin 18 ISO OMIM:114550 MouseDO NCBI chr11:49,073,733...49,081,706 JBrowse link
G LCAT lecithin-cholesterol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:59,495,936...59,500,530
Ensembl chr 5:59,497,115...59,500,448 		JBrowse link
G LECT2 leukocyte cell derived chemotaxin 2 ameliorates ISO human cells in mouse model
protein:increased expression:blood serum (human)
protein:increased expression:blood serum (mouse)		 RGD PMID:21394108 PMID:24892551 RGD:153323333 RGD:153323335 NCBI chr23:38,696,216...38,705,530
Ensembl chr23:38,696,203...38,705,087 		JBrowse link
G LEP leptin severity
susceptibility		 ISO protein:increased expression:liver (human)
DNA:SNP:enhancer:-2548G>A (rs7799039) (human)		 RGD PMID:18573568 PMID:28452232 RGD:15039399 RGD:25330348 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G LEPR leptin receptor susceptibility ISO associated with Hepatitis B, Chronic;DNA:missense mutations:cds:p.Q223R, p.K109R (human) RGD PMID:23090836 RGD:21079466 NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229 		JBrowse link
G LETM1 leucine zipper and EF-hand containing transmembrane protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23392203 NCBI chr27:46,912,882...46,954,295
Ensembl chr27:46,912,819...46,956,164 		JBrowse link
G LIFR LIF receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:37,307,753...37,385,489
Ensembl chr 4:37,314,347...37,362,137 		JBrowse link
G LOC103216161 uncharacterized LOC103216161 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:56,448,443...56,467,908
Ensembl chr 2:56,448,392...56,467,712 		JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21056497 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LOC103219825 protein patched homolog 1 severity
disease_progression		 ISO RGD PMID:18538319 PMID:22911366 RGD:150523837 RGD:150523842 NCBI chr12:107,580,895...107,656,443
Ensembl chr12:107,590,663...107,652,985 		JBrowse link
G LOC103223491 peroxisome proliferator-activated receptor alpha susceptibility ISO associated with hepatitis B;DNA:missense mutation:cds:p.L162V (human) RGD PMID:19119483 RGD:15042881 NCBI chr19:28,614,892...28,709,272
Ensembl chr19:28,615,413...28,708,763 		JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 no_association
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
DNA:deletion:cds (human)		 RGD
CTD		 PMID:7892276 PMID:11859714 PMID:20672314 PMID:20683151 RGD:14700951 RGD:14700979 RGD:7488953 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LOC103226928 aldo-keto reductase family 1 member B1 ISO protein:increased expression:liver (human)
protein:increased expression:liver (rat)		 RGD PMID:19422879 PMID:21683810 RGD:5509919 RGD:8548685 NCBI chr21:103,060,018...103,076,844
Ensembl chr21:103,059,991...103,077,341 		JBrowse link
G LOC103229692 solute carrier family 25 member 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr24:78,285,089...78,292,562
Ensembl chr24:78,285,593...78,292,773 		JBrowse link
G LOC103231165 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO ClinVar Annotator: match by term: Hepatocellular cancer RGD
ClinVar		 PMID:20946881 PMID:21250968 PMID:21596855 PMID:21997850 PMID:22160010 More... RGD:14985249 NCBI chr29:8,633,429...8,650,744
Ensembl chr29:8,633,715...8,650,657 		JBrowse link
G LOC103231897 properdin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:44,801,388...44,807,177
Ensembl chr  X:44,801,354...44,807,402 		JBrowse link
G LOC103233018 liver carboxylesterase 1 disease_progression ISO mRNA, protein:decreased expression:liver tumor (human)
associated with tumor vascularization; protein:decreased expression:liver tumor (human)
protein:decreased expression:liver (human)		 RGD PMID:19658107 PMID:24259486 PMID:30901224 RGD:152995276 RGD:152995279 RGD:152995286 NCBI chr 5:41,710,500...41,745,483 JBrowse link
G LOC103233229 cadherin-1 severity ISO DNA:hypermethylation
mRNA:increased expression:liver
protein:decreased expression:liver		 RGD PMID:17295234 PMID:18837082 PMID:24840851 PMID:30697077 RGD:14402045 RGD:14402046 RGD:14402047 RGD:2289638 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G LOC103233812 C-type lectin domain family 4 member G ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:7,206,303...7,211,213
Ensembl chr 6:7,206,712...7,209,431 		JBrowse link
G LOC103234663 interferon lambda-1 ameliorates ISO human protein and cells in mouse model RGD PMID:24769671 RGD:126848750 NCBI chr 6:33,901,382...33,904,356
Ensembl chr 6:33,901,801...33,903,894 		JBrowse link
G LOC103235252 leukocyte immunoglobulin-like receptor subfamily B member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:46,934,386...46,940,826 JBrowse link
G LOC103241760 ubiquitin-conjugating enzyme E2 E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr15:67,885,721...68,263,924 JBrowse link
G LOC103242767 C-C motif chemokine 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr16:29,887,799...29,897,664
Ensembl chr16:29,887,883...29,897,544 		JBrowse link
G LOC103242912 nucleoside diphosphate kinase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616 		JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B exacerbates
ameliorates		 ISO protein:increased expression:liver (human)
mRNA:increased expression:liver (human)		 RGD PMID:17047057 PMID:31485610 RGD:153298929 RGD:153298932 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More... NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G LOC103244924 cyclin-G1 severity
disease_progression
treatment		 ISO protein:decreased expression:liver (human)
protein:increased expression:liver (human)
human cells in mouse model		 RGD PMID:19584283 PMID:22835824 PMID:23804702 PMID:24034575 PMID:25431954 More... RGD:151356922 RGD:151356932 RGD:151356933 RGD:151356967 RGD:151356970 RGD:151356981 RGD:151361198 RGD:151361200 NCBI chr23:65,709,759...65,716,913
Ensembl chr23:65,709,786...65,714,711 		JBrowse link
G LOC103244927 hyaluronan mediated motility receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:65,732,343...65,765,511
Ensembl chr23:65,732,553...65,765,511 		JBrowse link
G LOC103245928 rho GTPase-activating protein 11B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:50,246,538...50,269,273
Ensembl chr26:50,245,229...50,269,418 		JBrowse link
G LOC103246803 mismatch repair endonuclease PMS2 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar NCBI chr28:15,174,359...15,209,962
Ensembl chr28:15,172,100...15,209,852 		JBrowse link
G LOC103248467 beta,beta-carotene 9',10'-oxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:103,511,730...103,566,526
Ensembl chr 1:103,521,658...103,565,659 		JBrowse link
G LOXL3 lysyl oxidase like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr14:32,722,588...32,745,480
Ensembl chr14:32,725,112...32,745,004 		JBrowse link
G LPA lipoprotein(a) ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:88,077,041...88,337,256 JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 ISO RGD PMID:19000703 RGD:2317680 NCBI chr12:28,502,717...28,669,581
Ensembl chr12:28,503,354...28,669,795 		JBrowse link
G LRAT lecithin retinol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:101,297,114...101,304,675
Ensembl chr 7:101,297,691...101,302,520 		JBrowse link
G LRP1B LDL receptor related protein 1B exacerbates ISO protein:increased expression:liver (human)
DNA:mutations:multiple: (human)		 RGD PMID:33324588 PMID:33391418 RGD:150429776 RGD:150429785 NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111 		JBrowse link
G LRRC1 leucine rich repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:18,627,810...18,751,074
Ensembl chr17:18,627,580...18,750,995 		JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More... NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633 		JBrowse link
G LRRC59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr16:42,931,726...42,949,281
Ensembl chr16:42,932,549...42,947,655 		JBrowse link
G LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:54,252,203...54,268,873
Ensembl chr 1:54,253,495...54,269,598 		JBrowse link
G LZTR1 leucine zipper like post translational regulator 1 ISO DNA:missense mutation:cds, liver (human) RGD PMID:28622513 RGD:151893487 NCBI chr19:4,917,381...4,935,174
Ensembl chr19:4,918,360...4,933,439 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:67,351,785...67,360,244 JBrowse link
G MAGEA1 MAGE family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:127,660,892...127,662,685
Ensembl chr  X:127,661,484...127,662,410 		JBrowse link
G MAGEA3 MAGE family member A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:127,271,604...127,276,373 JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 exacerbates ISO protein:increased expression:liver, cytosol (rat)
mRNA:increased expression:liver (human)		 RGD PMID:9397988 PMID:33553243 RGD:150530475 RGD:150530477 NCBI chr 6:3,848,441...3,881,367
Ensembl chr 6:3,848,401...3,881,412 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO protein:decreased expression:liver (human) RGD PMID:32850377 RGD:150429765 NCBI chr16:11,366,610...11,485,411
Ensembl chr16:11,366,751...11,486,125 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 exacerbates ISO mRNA:decreased expression:liver (human) RGD PMID:31310010 RGD:150573714 NCBI chr 4:53,040,731...53,120,784
Ensembl chr 4:53,084,023...53,120,772 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 ameliorates ISO RGD PMID:26560698 RGD:11342977
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 severity
ameliorates
treatment		 ISO human recombinant gene and cell line in a mouse model
human cell line in a mouse model		 RGD PMID:21196414 PMID:27010469 PMID:31922225 RGD:151347673 RGD:151347674 RGD:151347839 NCBI chr14:5,391,416...5,579,163
Ensembl chr14:5,391,449...5,583,916 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO protein:increased expression:liver RGD PMID:27468214 RGD:401976278 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 treatment
exacerbates		 ISO RGD PMID:23271722 PMID:25216638 RGD:151665347 RGD:151665348 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ameliorates ISO protein:decreased phosphorylation:liver (human) RGD PMID:33875785 RGD:150340688 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G MAPT microtubule associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:59,894,400...60,020,723
Ensembl chr16:59,890,221...59,955,612 		JBrowse link
G MARCO macrophage receptor with collagenous structure ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:11,329,036...11,389,428
Ensembl chr10:11,329,026...11,388,999 		JBrowse link
G MAT1A methionine adenosyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12060674 NCBI chr 9:51,540,162...51,558,076
Ensembl chr 9:51,540,162...51,558,576 		JBrowse link
G MBL2 mannose binding lectin 2 severity
susceptibility
no_association		 ISO associated with hepatitis C;DNA:SNP: :221C>G(rs709620)(human)
associated with hepatitis B-related cirrhosis;DNA:SNP: :rs11003123(G>A)(human)
associated with viral hepatitis;DNA:polymorphisms:exon:
associated with hepatitis B;DNA:SNP:exon:
DNA:SNPs:promoter:rs7096206(human)
protein:decreased expression:plasma		 RGD PMID:18221301 PMID:21733090 PMID:25787238 PMID:26857650 PMID:27298104 More... RGD:14696813 RGD:14696814 RGD:14696829 RGD:14696833 RGD:14696835 RGD:14696836 NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr 5:69,464,064...69,527,588
Ensembl chr 5:69,463,920...69,527,541 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr  X:20,319,731...20,364,603
Ensembl chr  X:20,319,807...20,361,847 		JBrowse link
G MCM10 minichromosome maintenance 10 replication initiation factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:13,200,018...13,252,830
Ensembl chr 9:13,204,246...13,253,367 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:53,419,958...53,452,720
Ensembl chr22:53,420,417...53,444,095 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 susceptibility ISO associated with hepatitis B;miRNA:increased expression:liver (human)
associated with hepatitis B;DNA:SNP:promoter: (rs999885) (human)		 RGD PMID:24416400 PMID:27298561 RGD:15042853 RGD:15042885 NCBI chr28:12,976,487...12,985,354
Ensembl chr28:12,977,013...12,985,898 		JBrowse link
G MCM9 minichromosome maintenance 9 homologous recombination repair factor ISO OMIM:114550 MouseDO NCBI chr13:54,945,668...55,069,869
Ensembl chr13:54,945,786...55,070,328 		JBrowse link
G MDM2 MDM2 proto-oncogene susceptibility ISO DNA:transversion:promoter:g.-309T>G (human) RGD PMID:20019189 RGD:2317357 NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890 		JBrowse link
G ME1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr13:7,889,211...8,112,793
Ensembl chr13:7,887,984...8,112,533 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11844796 PMID:26189965 RGD:2289670 NCBI chr  X:128,445,028...128,519,892
Ensembl chr  X:128,453,577...128,455,785 		JBrowse link
G MED1 mediator complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20007298 NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896 		JBrowse link
G MELK maternal embryonic leucine zipper kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:43,901,840...44,007,855
Ensembl chr12:43,901,551...44,007,266 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase severity ISO protein:increased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular cancer		 RGD
OMIM
ClinVar		 PMID:21774103 PMID:21970370 PMID:22703879 PMID:24728327 PMID:25741868 More... RGD:152995524 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:92,926,217...92,941,191
Ensembl chr20:92,926,067...92,941,159 		JBrowse link
G MHC-DPA1 major histocompatibility complex, class II, DP alpha 1 ISO DNA:hypomethylation: CpG islands: RGD PMID:20165882 RGD:14694974 NCBI chr17:39,009,361...39,017,978 JBrowse link
G MHC-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility ISO associated with Hepatitis B, Chronic;DNA:SNP: :rs9272105(human)
associated with Hepatitis B, Chronic;DNA:SNPs, haplotype: : rs9275572, rs2596542(human)		 RGD PMID:24204805 PMID:30160782 RGD:14398839 RGD:14401561 NCBI chr17:39,422,445...39,428,777
Ensembl chr17:39,420,134...39,428,871 		JBrowse link
G MKI67 marker of proliferation Ki-67 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866 		JBrowse link
G MLXIPL MLX interacting protein like ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr28:9,442,520...9,465,772 JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:8302012 RGD:13801035 NCBI chr15:35,577,460...35,681,730
Ensembl chr15:35,580,714...35,633,914 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20084675 NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:20084675 PMID:21681821 RGD:8547864 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712 		JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:66,935,212...66,952,446
Ensembl chr 1:66,935,584...66,951,891 		JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor ISO human cells in mouse model RGD PMID:23157389 RGD:126925755 NCBI chr20:89,457,549...89,474,756
Ensembl chr20:89,459,493...89,474,352 		JBrowse link
G MPO myeloperoxidase disease_progression
susceptibility		 ISO associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-463G>A(human)
associated with liver cirrhosis; DNA:SNP:promoter:-463G>A( rs2333227)(human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19731237 PMID:21907168 RGD:26923907 RGD:27095879 NCBI chr16:35,120,194...35,130,851
Ensembl chr16:35,120,581...35,130,671 		JBrowse link
G MRO maestro ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:30,149,163...30,177,547
Ensembl chr18:30,166,834...30,181,570 		JBrowse link
G MSH3 mutS homolog 3 ISO ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:28492532 NCBI chr 4:74,811,181...75,032,067
Ensembl chr 4:74,811,198...75,032,005 		JBrowse link
G MSH5 mutS homolog 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:40,260,979...40,283,872
Ensembl chr17:40,261,125...40,282,511 		JBrowse link
G MTBP MDM2 binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:29765550 NCBI chr 8:115,023,272...115,109,948
Ensembl chr 8:115,029,029...115,102,088 		JBrowse link
G MTDH metadherin treatment ISO human cells in a mouse model RGD PMID:26351209 RGD:11096879 NCBI chr 8:92,563,480...92,641,874
Ensembl chr 8:92,563,550...92,640,231 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase ISO mRNA:increased expression:liver RGD PMID:3878730 RGD:2302305 NCBI chr14:33,063,485...33,080,703
Ensembl chr14:33,064,542...33,080,366 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase onset
susceptibility
disease_progression		 ISO DNA:SNP: :1298A>C(human)
DNA:SNPs: :677C>T, 1298A>C(human)
DNA:SNP: :677C>T(human)
DNA:SNP,haplotype: :677C>T, 1298A>C(human)		 RGD PMID:17503006 PMID:17659576 PMID:19035314 PMID:23996892 RGD:14696703 RGD:14696704 RGD:14696707 RGD:14696708 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950 		JBrowse link
G MTOR mechanistic target of rapamycin kinase severity ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (human)		 CTD
RGD		 PMID:21147110 PMID:25371154 RGD:152995471 NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:SNP: :66A>G(human) RGD PMID:19035314 RGD:14696707 NCBI chr 4:7,461,521...7,493,032
Ensembl chr 4:7,461,526...7,493,840 		JBrowse link
G MVK mevalonate kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr11:104,812,882...104,837,089
Ensembl chr11:104,813,846...104,835,517 		JBrowse link
G MYBL2 MYB proto-oncogene like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:20,097,179...20,148,998
Ensembl chr 2:20,097,108...20,148,926 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity
treatment		 ISO mRNA:increased expression:liver (human)
OMIM:114550
mRNA:increased expression:liver (rat)
CTD Direct Evidence: marker/mechanism		 RGD
MouseDO
CTD		 PMID:9029167 PMID:12029619 PMID:15565109 PMID:21644509 PMID:22076107 More... RGD:6903288 RGD:7240567 RGD:7240695 RGD:7241004 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor exacerbates
treatment
ameliorates		 ISO mRNA:increased expression:liver (human)
human gene and cell in a mouse model
mouse cell line in a mouse model
protein:increased expression:liver (human)
human cell line in a mouse model
protein, mRNA:decreased expression:liver (human)		 RGD PMID:17615358 PMID:24603331 PMID:26985932 PMID:28370778 PMID:29022910 More... RGD:150520022 RGD:150520169 RGD:150521532 RGD:150521534 RGD:150524327 RGD:150524329 RGD:150524330 RGD:150524334 RGD:150530285 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G NAT2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:16,451,144...16,494,961
Ensembl chr 8:16,493,749...16,494,621 		JBrowse link
G NBN nibrin ISO ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More... NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028 		JBrowse link
G NCAPG non-SMC condensin I complex subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr27:32,380,722...32,413,659
Ensembl chr27:32,377,575...32,413,494 		JBrowse link
G NCAPH non-SMC condensin I complex subunit H ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:755,840...792,053
Ensembl chr14:755,897...792,154 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 exacerbates ISO RGD PMID:22556267 PMID:28273073 RGD:153002573 RGD:153002576 NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947 		JBrowse link
G NDC80 NDC80 kinetochore complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:61,835,027...61,882,660
Ensembl chr18:61,835,064...61,881,627 		JBrowse link
G NEIL3 nei like DNA glycosylase 3 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr 7:123,408,582...123,462,475
Ensembl chr 7:123,409,363...123,462,411 		JBrowse link
G NEK2 NIMA related kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:17,816,929...17,847,348
Ensembl chr25:17,829,546...17,842,463 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor disease_progression ISO protein:decreased expression:liver
DNA, protein:SNP, increased expression:intron, liver		 RGD PMID:26443326 PMID:27289045 PMID:29130106 RGD:11076529 RGD:150530489 RGD:150530504 NCBI chr19:12,474,479...12,572,144
Ensembl chr19:12,474,468...12,572,250 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 ISO OMIM:114550 MouseDO NCBI chr16:68,449,601...68,463,030
Ensembl chr16:68,449,898...68,461,190 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 PMID:29018201 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 disease_progression
treatment		 ISO associated with Chronic Hepatitis B;DNA:insertion/deletion:3'utr: -94ins/delATTG (rs28720239) (human) RGD PMID:19797428 PMID:25999787 RGD:152177911 RGD:40400751 NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498 		JBrowse link
G NFKBIA NFKB inhibitor alpha disease_progression
susceptibility		 ISO CTD Direct Evidence: therapeutic
associated with Chronic Hepatitis B;DNA:SNPs,haplotype:3'utr,promoter: 826C>T,881A>G (rs2233406,rs3138053) (human)
associated with hepatitis B;DNA:SNP:promoter:-826C>T (rs2233406) (human)		 CTD
RGD		 PMID:19797428 PMID:22022477 PMID:25223483 RGD:40400751 RGD:40902986 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NKX3-1 NK3 homeobox 1 treatment ISO human gene in a mouse model
mRNA:decreased expression:liver		 RGD PMID:28972178 RGD:14401599 NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319 		JBrowse link
G NLRC3 NLR family CARD domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30081150 NCBI chr 5:3,241,552...3,262,763
Ensembl chr 5:3,242,242...3,262,261 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 ISO protein:increased expression:liver RGD PMID:27338800 RGD:15003194 NCBI chr 5:42,942,875...43,035,043
Ensembl chr 5:42,974,300...43,035,351 		JBrowse link
G NNMT nicotinamide N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:105,650,178...105,708,441
Ensembl chr 1:105,690,085...105,713,010 		JBrowse link
G NOS2 nitric oxide synthase 2 treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257 		JBrowse link
G NOTCH3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:13,762,570...13,803,676
Ensembl chr 6:13,761,512...13,793,359 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23811326 NCBI chr20:105,850,328...105,853,076
Ensembl chr20:105,850,598...105,853,060 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 6:43,438,428...43,445,190
Ensembl chr 6:43,437,950...43,446,063 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO mRNA:splice variant(s):liver (human)
OMIM:114550
intestinally expressed human gene in mouse model
CTD Direct Evidence: marker/mechanism		 RGD
MouseDO
CTD		 PMID:23213087 PMID:23811326 PMID:24954587 PMID:25496033 RGD:14696796 RGD:14928330 RGD:14928334 NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression
severity		 ISO human gene in mouse model
ClinVar Annotator: match by term: Hepatocellular cancer
mRNA, protein:increased expression:liver (mouse, human)		 RGD
ClinVar		 PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... RGD:14696775 RGD:14696793 NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G NRG1 neuregulin 1 disease_progression ISO mRNA:increased expression:liver (human)
associated with hepatitis C;mRNA:altered expression:liver (human		 RGD PMID:17393520 PMID:27514687 RGD:39456104 RGD:39456110 NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487 		JBrowse link
G NRP1 neuropilin 1 disease_progression ISO protein:decreased expression:liver RGD PMID:25333267 RGD:126848812 NCBI chr 9:32,474,787...32,632,746
Ensembl chr 9:32,474,309...32,633,101 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex disease_progression
treatment		 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28284560 PMID:30653265 PMID:31933938 RGD:28867240 RGD:28912742 NCBI chr25:65,462,608...65,493,242
Ensembl chr25:65,462,603...65,493,246 		JBrowse link
G NUSAP1 nucleolar and spindle associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:41,624,507...41,667,568
Ensembl chr26:41,624,894...41,667,548 		JBrowse link
G OIT3 oncoprotein induced transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:58,338,703...58,378,492
Ensembl chr 9:58,337,958...58,377,734 		JBrowse link
G OLFML2A olfactomedin like 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:13,334,339...13,368,610
Ensembl chr12:13,335,805...13,451,675 		JBrowse link
G OLFML2B olfactomedin like 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:2,053,696...2,094,142
Ensembl chr20:2,053,852...2,094,126 		JBrowse link
G ORC1 origin recognition complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:80,540,331...80,571,989
Ensembl chr20:80,542,532...80,572,237 		JBrowse link
G OTC ornithine transcarbamylase severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr  X:35,494,334...35,570,923
Ensembl chr  X:35,494,287...35,570,845 		JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 disease_progression ISO mRNA,protein:decreased expression:liver: RGD PMID:21569763 RGD:12790589 NCBI chr16:2,270,126...2,293,705
Ensembl chr16:2,270,085...2,296,825 		JBrowse link
G PAMR1 peptidase domain containing associated with muscle regeneration 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:29,732,311...29,833,646
Ensembl chr 1:29,774,155...29,833,117 		JBrowse link
G PARK7 Parkinsonism associated deglycase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr20:123,776,084...123,808,031
Ensembl chr20:123,776,297...123,798,434 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18695907 NCBI chr25:3,350,798...3,405,040 JBrowse link
G PBK PDZ binding kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:25,921,124...25,943,349
Ensembl chr 8:25,921,133...25,943,062 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 2:6,550,806...6,556,499
Ensembl chr 2:6,549,652...6,556,478 		JBrowse link
G PCLAF PCNA clamp associated factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:19,140,901...19,155,488
Ensembl chr26:19,140,843...19,155,730 		JBrowse link
G PCNA proliferating cell nuclear antigen treatment ISO protein:increased expression:liver: RGD PMID:23219601 PMID:25999787 RGD:10448993 RGD:152177911 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G PDCD1 programmed cell death 1 disease_progression ISO associated with hepatitis B
associated with hepatitis B;DNA:SNP: : +8669 A>G (human)		 RGD PMID:21912640 PMID:27034168 RGD:40818257 RGD:41410800 NCBI chr10:127,877,383...127,886,234
Ensembl chr10:127,878,554...127,886,088 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20506153 NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395 		JBrowse link
G PDGFRL platelet derived growth factor receptor like ISO ClinVar Annotator: match by term: Hepatocellular carcinoma OMIM
ClinVar		 PMID:7898930 NCBI chr 8:15,671,827...15,739,396
Ensembl chr 8:15,671,425...15,738,199 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr26:39,273,982...39,300,170
Ensembl chr26:39,272,997...39,349,966 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28003426 NCBI chr21:53,445,607...53,458,729
Ensembl chr21:53,445,457...53,460,776 		JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase ISO protein:increased activity:hepatoma (rat)
protein:increased expression:liver		 RGD PMID:6722784 RGD:5135276 NCBI chr16:7,618,952...7,639,700
Ensembl chr16:7,623,817...7,638,594 		JBrowse link
G PFN2 profilin 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr15:40,718,892...40,726,731 JBrowse link
G PGD phosphogluconate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr20:121,359,854...121,380,934 JBrowse link
G PGK1 phosphoglycerate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr  X:67,072,029...67,093,881 JBrowse link
G PHB1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754 		JBrowse link
G PHF6 PHD finger protein 6 exacerbates ISO mRNA:increased expression:liver (human) RGD PMID:30888215 PMID:31329335 RGD:155260288 RGD:155260308 NCBI chr  X:109,531,700...109,595,136
Ensembl chr  X:109,531,726...109,593,854 		JBrowse link
G PHLDA1 pleckstrin homology like domain family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:71,621,536...71,630,051 JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha treatment
susceptibility
severity
no_association		 ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:SNPs: :rs17849071,rs17849079(human)
DNA:mutations:exons:
DNA:mutation:exon:		 OMIM
ClinVar
RGD		 PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... RGD:11556371 RGD:14402404 RGD:14402405 RGD:152177911 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 treatment ISO RGD PMID:25999787 PMID:31801250 RGD:151893509 RGD:152177911 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr 6:16,620,673...16,637,511
Ensembl chr 6:16,621,606...16,636,937 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr20:86,651,692...86,748,670
Ensembl chr20:86,651,520...86,745,116 		JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 disease_progression ISO associated with Chronic Hepatitis B; DNA:SNP::rs1469557(human) RGD PMID:27221889 RGD:152977752 NCBI chr 8:8,259,537...8,336,586
Ensembl chr 8:8,259,692...8,336,603 		JBrowse link
G PITPNM3 PITPNM family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:5,830,107...5,934,979
Ensembl chr16:5,834,088...5,916,697 		JBrowse link
G PITX1 paired like homeodomain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:37,807,486...37,820,540
Ensembl chr23:37,807,378...37,813,948 		JBrowse link
G PKM pyruvate kinase M1/2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr26:11,224,332...11,255,538 JBrowse link
G PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:2,712,423...2,722,122
Ensembl chr 5:2,712,448...2,716,661 		JBrowse link
G PKP1 plakophilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr25:28,083,358...28,129,356
Ensembl chr25:28,081,983...28,128,173 		JBrowse link
G PLAC8 placenta associated 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:31,471,166...31,496,053
Ensembl chr 7:31,470,774...31,489,432 		JBrowse link
G PLAU plasminogen activator, urokinase ISO OMIM:114550 MouseDO NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286 		JBrowse link
G PLCG1 phospholipase C gamma 1 ameliorates ISO human cell line in a mouse model RGD PMID:30623526 RGD:151356937 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PLK1 polo like kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:21,388,957...21,408,574
Ensembl chr 5:21,396,204...21,410,718 		JBrowse link
G PLK4 polo like kinase 4 sexual_dimorphism ISO DNA:hypermethylation:promoter RGD PMID:21324136 RGD:27226690 NCBI chr 7:75,005,468...75,023,768
Ensembl chr 7:75,006,431...75,023,730 		JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 treatment ISO mRNA, protein:increased expression:liver (human) RGD PMID:29059470 RGD:155791679 NCBI chr28:11,962,394...11,974,206
Ensembl chr28:11,962,286...11,975,228 		JBrowse link
G PLVAP plasmalemma vesicle associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:15,857,945...15,879,022
Ensembl chr 6:15,857,947...15,879,058 		JBrowse link
G PLXDC1 plexin domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:67,015,482...67,102,761
Ensembl chr16:67,016,829...67,106,635 		JBrowse link
G PML PML nuclear body scaffold ameliorates
disease_progression
exacerbates		 ISO mRNA:increased expression:liver (mouse)
protein:increased expression:liver (human)
associated with hepatitis C		 RGD PMID:11511788 PMID:26118777 PMID:31144474 RGD:41404685 RGD:41404687 RGD:41404690 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 ISO associated with Hepatitis C, Chronic;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:21319195 RGD:14981585 NCBI chr19:26,435,302...26,458,368
Ensembl chr19:26,435,599...26,462,210 		JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr14:51,211,385...51,267,706
Ensembl chr14:51,211,118...51,267,098 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit susceptibility ISO DNA:SNPs:introns: (rs1061316, rs758130) (human) RGD PMID:28457473 RGD:15039387 NCBI chr29:7,864,319...7,881,577
Ensembl chr29:7,863,277...7,882,068 		JBrowse link
G PON1 paraoxonase 1 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875 		JBrowse link
G POT1 protection of telomeres 1 disease_progression ISO associated with hepatitis B;DNA:SNP: :rs7784168(human) RGD PMID:23907815 RGD:152975963 NCBI chr21:93,572,139...93,688,374
Ensembl chr21:93,571,272...93,655,869 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha susceptibility ISO associated with hepatitis B;DNA:missense mutation:cds:p.L162V (human) RGD PMID:19119483 RGD:15042881
G PPARG peroxisome proliferator activated receptor gamma severity ISO CTD Direct Evidence: therapeutic
protein:decreased expression:liver		 CTD
RGD		 PMID:16374840 PMID:27451128 RGD:14694822 NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr 7:12,201,434...12,242,418
Ensembl chr 7:12,191,784...12,243,488 		JBrowse link
G PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15010824 NCBI chr11:50,695,896...50,704,191
Ensembl chr11:50,696,032...50,704,219 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A onset ISO protein:increased expression:liver (rat) RGD PMID:20935162 RGD:10002734 NCBI chr21:53,744,202...54,129,709
Ensembl chr21:53,747,857...54,127,005 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B severity ISO mRNA, protein:decreased expression:liver (human) RGD PMID:23591196 RGD:10043803 NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680 		JBrowse link
G PPP4R3C protein phosphatase 4 regulatory subunit 3C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:25,913,708...25,917,148 JBrowse link
G PRC1 protein regulator of cytokinesis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr29:8,866,919...8,895,832
Ensembl chr29:8,866,969...8,894,691 		JBrowse link
G PRDM1 PR/SET domain 1 disease_progression ISO associated with hepatitis B;
associated with hepatitis B;DNA:SNP: :rs1010273(human)		 RGD PMID:31100710 PMID:31376415 RGD:150530465 RGD:150530466 NCBI chr13:67,695,436...67,719,487
Ensembl chr13:67,695,309...67,718,931 		JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr20:87,267,026...87,277,634
Ensembl chr20:87,267,044...87,279,978 		JBrowse link
G PRDX2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 6:11,484,452...11,489,067
Ensembl chr 6:11,481,784...11,489,051 		JBrowse link
G PRDX6 peroxiredoxin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr25:55,706,920...55,719,196
Ensembl chr25:55,706,885...55,718,665 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 exacerbates ISO protein:increased expression:liver (human)
mRNA:increased expression:liver (human)
mRNA:decreased expression:liver (human)		 RGD PMID:25151370 PMID:28000796 PMID:28205209 PMID:31776854 RGD:151665185 RGD:151665186 RGD:151665188 RGD:151665343 NCBI chr 8:63,781,892...64,061,222
Ensembl chr 8:63,781,948...64,060,864 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase severity ISO protein:decreased expression:liver (human) RGD PMID:28862485 RGD:13432206 NCBI chr13:88,856,056...90,329,379 JBrowse link
G PRL prolactin onset ISO protein:increased expression:serum (human) RGD PMID:22392353 RGD:125097525 NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631 		JBrowse link
G PROM1 prominin 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr27:34,093,699...34,243,630
Ensembl chr27:34,129,532...34,243,778 		JBrowse link
G PTEN phosphatase and tensin homolog severity
treatment
exacerbates		 ISO associated with hepatitis B;protein:decreased expression:liver (human)
OMIM:114550
CTD Direct Evidence: marker/mechanism
associated with hepatitis C, liver cirrhosis;protein:decreased expression:liver (human)		 RGD
MouseDO
CTD		 PMID:12115563 PMID:12673720 PMID:27022031 PMID:29303510 PMID:30690477 More... RGD:127285591 RGD:127285603 RGD:127285610 RGD:151893509 RGD:152995524 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 treatment
susceptibility
severity		 ISO mRNA,protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter:-1195A>G (rs689466) (human)
protein:increased expression:liver, cytosol		 RGD
CTD		 PMID:11872629 PMID:12024111 PMID:14563831 PMID:15800977 PMID:16374840 More... RGD:14695010 RGD:14695011 RGD:14695012 RGD:152177911 RGD:2300283 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G PTH1R parathyroid hormone 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:8,287,877...8,309,736
Ensembl chr22:8,289,398...8,311,256 		JBrowse link
G PTK2 protein tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:14578863 PMID:17203219 RGD:2292584 NCBI chr 8:134,897,511...135,246,300 JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 disease_progression
susceptibility		 ISO DNA:SNP: :p.Y2081D(human) RGD PMID:16489062 PMID:26801674 RGD:152176666 RGD:152599190 NCBI chr 7:34,974,028...35,200,214
Ensembl chr 7:34,974,082...35,200,293 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:30237408 RGD:151361293 NCBI chr11:66,095,445...66,222,402
Ensembl chr11:66,101,038...66,221,982 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:62,781,184...62,787,832 JBrowse link
G PYCARD PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:17471463 NCBI chr 5:27,892,332...27,894,386
Ensembl chr 5:27,889,230...27,893,697 		JBrowse link
G PYGL glycogen phosphorylase L ISO CTD Direct Evidence: marker/mechanism CTD PMID:2885971 NCBI chr24:27,987,676...28,030,919
Ensembl chr24:27,987,649...28,030,869 		JBrowse link
G PZP PZP alpha-2-macroglobulin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:8,963,883...9,023,148
Ensembl chr11:8,963,461...9,014,957 		JBrowse link
G RAC1 Rac family small GTPase 1 exacerbates ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:18506888 PMID:20522449 PMID:33482578 RGD:153298967 RGD:153350129 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:46,218,987...46,260,477
Ensembl chr11:46,220,090...46,254,602 		JBrowse link
G RAD21 RAD21 cohesin complex component susceptibility
exacerbates
treatment		 ISO associated with hepatitis c, liver cirrhosis;mRNA:increased expression:liver (human)
protein:increased expression:liver (human)
human cells in a mouse model		 RGD PMID:28434945 PMID:30698808 PMID:32596342 PMID:33251678 RGD:150520026 RGD:150520029 RGD:150520030 RGD:150520035 NCBI chr 8:111,486,356...111,515,641
Ensembl chr 8:111,486,048...111,507,729 		JBrowse link
G RAD50 RAD50 double strand break repair protein ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:16385572 PMID:18281469 PMID:19409520 PMID:24894818 PMID:25452441 More... NCBI chr23:35,375,206...35,458,801
Ensembl chr23:35,375,305...35,458,622 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein onset
susceptibility		 ISO mRNA,protein:increased expression:liver (human)
associated with hepatitis B;DNA:SNP:3'utr: (rs7963551) (human)		 RGD PMID:24729511 PMID:31719794 RGD:151361199 RGD:151361207 NCBI chr11:893,984...989,119
Ensembl chr11:895,292...927,430 		JBrowse link
G RAD54L RAD54 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:86,510,616...86,542,426
Ensembl chr20:86,507,248...86,542,663 		JBrowse link
G RARA retinoic acid receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr16:65,817,849...65,866,862
Ensembl chr16:65,817,757...65,866,878 		JBrowse link
G RB1 RB transcriptional corepressor 1 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12029619 PMID:14961299 PMID:33841550 RGD:152998960 NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546 		JBrowse link
G RBM10 RNA binding motif protein 10 disease_progression ISO mRNA:decreased expression:liver RGD PMID:32572914 RGD:151356975 NCBI chr  X:44,339,653...44,373,509
Ensembl chr  X:44,339,877...44,373,339 		JBrowse link
G RCAN1 regulator of calcineurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:78,561,212...78,658,023
Ensembl chr 2:78,562,795...78,571,498 		JBrowse link
G RECQL RecQ like helicase disease_progression ISO protein:increased expression:liver RGD PMID:18422747 RGD:2317370 NCBI chr11:21,334,601...21,366,943
Ensembl chr11:21,331,584...21,366,979 		JBrowse link
G RET ret proto-oncogene severity ISO protein:increased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular carcinoma		 RGD
ClinVar		 PMID:7784092 PMID:7845675 PMID:7911697 PMID:9111992 PMID:9242375 More... RGD:150340602 NCBI chr 9:38,746,088...38,798,773
Ensembl chr 9:38,769,170...38,796,712 		JBrowse link
G RGN regucalcin ISO protein:decreased expression:liver RGD PMID:21683810 RGD:5509919 NCBI chr  X:44,282,825...44,299,027
Ensembl chr  X:44,285,601...44,299,258 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 severity ISO mRNA, protein:increased expression:liver (human) RGD PMID:25371154 PMID:29303510 RGD:152995471 RGD:152995524 NCBI chr 4:37,758,531...37,885,323
Ensembl chr 4:37,762,901...37,873,766 		JBrowse link
G RIT1 Ras like without CAAX 1 ameliorates ISO human cells in mouse model RGD PMID:31247273 RGD:152999016 NCBI chr20:7,965,944...7,979,396
Ensembl chr20:7,966,057...7,976,819 		JBrowse link
G RND3 Rho family GTPase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:35,877,147...35,897,318
Ensembl chr10:35,877,153...35,897,286 		JBrowse link
G RNF157 ring finger protein 157 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:45,438,603...45,536,270
Ensembl chr16:45,438,672...45,538,600 		JBrowse link
G RNF43 ring finger protein 43 exacerbates ISO human cells in a mouse model RGD PMID:23136185 RGD:151361219 NCBI chr16:34,981,126...35,046,478
Ensembl chr16:34,980,922...35,045,107 		JBrowse link
G RNF6 ring finger protein 6 disease_progression ISO RGD PMID:30496760 RGD:151665757 NCBI chr 3:5,461,053...5,471,268
Ensembl chr 3:5,462,126...5,468,555 		JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:97,178,093...98,363,647
Ensembl chr22:98,222,891...98,363,219 		JBrowse link
G RPS6 ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr12:60,353,800...60,357,797
Ensembl chr12:60,353,817...60,357,759 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr  X:18,614,664...18,730,591
Ensembl chr  X:18,620,159...18,730,581 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr 1:62,606,112...62,649,979
Ensembl chr 1:62,604,486...62,650,200 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 PMID:28284560 NCBI chr14:97,512,690...97,519,734
Ensembl chr14:97,512,832...97,521,932 		JBrowse link
G RSPO3 R-spondin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:46,530,423...46,606,900
Ensembl chr13:46,530,355...46,606,730 		JBrowse link
G RTKN rhotekin ISO mRNA:increased expression:liver RGD PMID:27922690 RGD:19165144 NCBI chr14:32,835,660...32,851,799
Ensembl chr14:32,837,546...32,855,912 		JBrowse link
G RTP3 receptor transporter protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17693185 NCBI chr22:7,925,733...7,930,132
Ensembl chr22:7,926,804...7,931,187 		JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver		 CTD
RGD		 PMID:17094378 PMID:28458013 RGD:126775147 NCBI chr20:107,769,244...107,802,154
Ensembl chr20:107,736,683...107,802,307 		JBrowse link
G RXRA retinoid X receptor alpha ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678 		JBrowse link
G S100A9 S100 calcium binding protein A9 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr20:10,391,965...10,395,216
Ensembl chr20:10,391,934...10,394,720 		JBrowse link
G SARDH sarcosine dehydrogenase severity ISO mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr12:4,397,312...4,469,890
Ensembl chr12:4,397,539...4,469,562 		JBrowse link
G SAV1 salvador family WW domain containing protein 1 ISO OMIM:114550 MouseDO NCBI chr24:27,710,256...27,747,638
Ensembl chr24:27,711,970...27,747,647 		JBrowse link
G SCAP SREBF chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr22:8,821,809...8,887,538
Ensembl chr22:8,818,980...8,850,202 		JBrowse link
G SCD stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 9:93,380,812...93,398,860
Ensembl chr 9:93,380,914...93,398,912 		JBrowse link
G SERPINA1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6258829 PMID:21472284 NCBI chr24:72,158,521...72,171,139
Ensembl chr24:72,156,784...72,163,500 		JBrowse link
G SERPINA4 serpin family A member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:19709125 NCBI chr24:72,345,566...72,356,257
Ensembl chr24:72,347,261...72,356,416 		JBrowse link
G SERPINB5 serpin family B member 5 disease_progression ISO associated with hepatitis B; RGD PMID:26296971 RGD:11520929 NCBI chr18:16,256,700...16,284,410
Ensembl chr18:16,256,552...16,283,764 		JBrowse link
G SERPINF1 serpin family F member 1 ISO associated with Human Viral Hepatitis, liver cirrhosis;protein:increased expression:serum (human) RGD PMID:27748324 RGD:27226704 NCBI chr16:1,408,453...1,424,197 JBrowse link
G SET SET nuclear proto-oncogene ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26822237 NCBI chr12:9,446,265...9,453,991 JBrowse link
G SF3B1 splicing factor 3b subunit 1 treatment
disease_progression		 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma
mRNA, protein:increased expression:liver		 RGD
ClinVar		 PMID:23634996 PMID:26619011 PMID:33038489 RGD:126790494 NCBI chr10:82,901,908...82,952,094
Ensembl chr10:82,899,079...82,952,071 		JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 NCBI chr 1:8,189,636...8,207,024
Ensembl chr 1:8,189,446...8,207,020 		JBrowse link
G SF3B4 splicing factor 3b subunit 4 severity
treatment		 ISO mRNA, protein:increased expression:liver (human)
mRNA, protein:increased expression:liver(human)
human cells in mouse model
mRNA, protein:increased expression:liver (rat)		 RGD PMID:29059470 PMID:30391496 RGD:155791679 RGD:155804298
G SFN stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr20:105,902,481...105,904,313
Ensembl chr20:105,902,974...105,903,720 		JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984 		JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33838155 NCBI chr 6:4,090,800...4,130,566
Ensembl chr 6:4,091,359...4,130,578 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO protein:increased expression, increased phosphorylation:hepatocyte RGD PMID:15375560 RGD:1643188 NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610 		JBrowse link
G SHH sonic hedgehog signaling molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G SIK2 salt inducible kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34491613 NCBI chr 1:102,944,171...103,070,973
Ensembl chr 1:102,944,281...103,068,823 		JBrowse link
G SIX1 SIX homeobox 1 severity ISO protein:increased expression:liver (human) RGD PMID:17008870 RGD:11561961 NCBI chr24:37,840,399...37,855,801
Ensembl chr24:37,840,309...37,845,192 		JBrowse link
G SKA1 spindle and kinetochore associated complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:30,562,320...30,579,966
Ensembl chr18:30,560,284...30,579,938 		JBrowse link
G SKA3 spindle and kinetochore associated complex subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:32,645...57,771 JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver		 CTD
RGD		 PMID:12717389 PMID:19533683 RGD:2315050 NCBI chr 4:35,009,114...35,040,518
Ensembl chr 4:35,009,076...35,042,632 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:87,744,600...87,780,846
Ensembl chr13:87,745,023...87,781,073 		JBrowse link
G SLC26A6 solute carrier family 26 member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:10,035,676...10,046,274
Ensembl chr22:10,035,478...10,045,304 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr20:89,974,567...90,007,977
Ensembl chr20:90,002,030...90,008,033 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr15:18,434,370...18,466,331
Ensembl chr15:18,434,916...18,467,352 		JBrowse link
G SLC38A1 solute carrier family 38 member 1 ameliorates
disease_progression		 ISO RGD PMID:26389641 RGD:151361140 NCBI chr11:42,415,986...42,502,794
Ensembl chr11:42,421,910...42,472,838 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 ISO CTD Direct Evidence: therapeutic CTD PMID:15347726 PMID:15520214 NCBI chr 6:16,346,361...16,367,833 JBrowse link
G SLC7A5 solute carrier family 7 member 5 ameliorates
disease_progression		 ISO mRNA:increased expression:liver RGD PMID:7532544 PMID:23696029 PMID:26389641 RGD:151361140 RGD:151361280 RGD:634202 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 disease_progression
exacerbates		 ISO protein:decreased expression:liver (human)
mRNA,protein:decreased expression:liver (human)		 RGD PMID:21626360 PMID:32534581 RGD:152995417 RGD:152995423 NCBI chr11:20,637,429...20,760,577
Ensembl chr11:20,648,582...20,761,161 		JBrowse link
G SLIT2 slit guidance ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19100240 NCBI chr27:29,650,589...30,020,105
Ensembl chr27:29,650,337...29,803,612 		JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:18971187 RGD:12880056 NCBI chr18:33,017,138...33,105,320
Ensembl chr18:33,017,492...33,104,606 		JBrowse link
G SMAD4 SMAD family member 4 disease_progression ISO protein:decreased expression:liver
protein:increased expression:liver:		 RGD PMID:18971187 PMID:22799322 PMID:23922662 PMID:29924446 RGD:12880056 RGD:18182921 RGD:21066341 RGD:21066342 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478 		JBrowse link
G SMAD7 SMAD family member 7 ISO mRNA:increased expression:liver (human) RGD PMID:25602745 RGD:14401589 NCBI chr18:31,993,543...32,024,088
Ensembl chr18:31,993,681...32,024,850 		JBrowse link
G SMARCA4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 ISO DNA:SNPs: :rs11879293, rs2072382 (human) RGD PMID:24556940 RGD:127285650 NCBI chr 6:9,943,162...10,044,476 JBrowse link
G SMARCB1 SWI/SNF related BAF chromatin remodeling complex subunit B1 disease_progression ISO mRNA:decreased expression:liver RGD PMID:27111394 RGD:127285647 NCBI chr19:6,902,985...6,945,111
Ensembl chr19:6,902,951...6,944,784 		JBrowse link
G SMARCC1 SWI/SNF related BAF chromatin remodeling complex subunit C1 ameliorates ISO mRNA, protein:increased expression:liver (human) RGD PMID:32514535 RGD:151347860 NCBI chr22:8,987,936...9,167,689
Ensembl chr22:8,987,012...9,134,946 		JBrowse link
G SMC3 structural maintenance of chromosomes 3 exacerbates ISO mRNA:increased editing:cds:p.K96R,p.Q103R(human) RGD PMID:29996118 RGD:156430111 NCBI chr 9:103,506,779...103,543,836
Ensembl chr 9:103,506,689...103,545,523 		JBrowse link
G SMG9 SMG9 nonsense mediated mRNA decay factor severity ISO RGD PMID:34456727 RGD:155882446 NCBI chr 6:37,253,023...37,277,536
Ensembl chr 6:37,250,791...37,277,557 		JBrowse link
G SMO smoothened, frizzled class receptor disease_progression ISO DNA:SNP: :rs3824 (human) RGD PMID:25944162 RGD:150340548 NCBI chr21:97,788,955...97,814,549
Ensembl chr21:97,788,624...97,814,709 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr 2:13,988,059...13,993,780
Ensembl chr 2:13,988,024...13,993,746 		JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E ISO human gene in a mouse model RGD PMID:21688285 RGD:10768833 NCBI chr25:25,474,620...25,483,427 JBrowse link
G SNW1 SNW domain containing 1 severity ISO protein:increased expression:liver (human) RGD PMID:23696020 RGD:11035253 NCBI chr24:54,976,597...55,020,051
Ensembl chr24:54,977,083...55,019,988 		JBrowse link
G SNX27 sorting nexin 27 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36029209 NCBI chr20:11,997,768...12,083,929
Ensembl chr20:11,998,527...12,083,528 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 exacerbates ISO associated with hepatitis B;protein:increased expression:liver (human) RGD PMID:30814741 RGD:126925204 NCBI chr25:49,998,197...50,061,433
Ensembl chr25:50,001,910...50,061,173 		JBrowse link
G SOAT2 sterol O-acyltransferase 2 ISO RGD PMID:16274362 RGD:1581190 NCBI chr11:49,214,295...49,228,268
Ensembl chr11:49,215,034...49,228,244 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 treatment ISO associated with liver cirrhosis;DNA:altered methylation:liver:
DNA:hypermethylation:CpG island, 5'untranslated region:		 RGD PMID:14614012 PMID:15235874 PMID:18843197 PMID:22318090 RGD:150573687 RGD:150573689 RGD:150573700 RGD:150573703 NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991 		JBrowse link
G SOCS2 suppressor of cytokine signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:88,964,805...88,971,147
Ensembl chr11:88,966,940...88,971,515 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16831601 NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423 		JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr 2:60,461,219...60,472,999 JBrowse link
G SOD2 superoxide dismutase 2 disease_progression
susceptibility		 ISO associated with liver cirrhosis; DNA:SNP:cds:p.Ala16Val(rs1799725)(human)
protein:increased expression:saliva
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15869407 PMID:16767786 PMID:18760346 PMID:19731237 PMID:21472284 More... RGD:1581242 RGD:26923907 RGD:26923955 RGD:27095881 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974 		JBrowse link
G SOX30 SRY-box transcription factor 30 disease_progression
exacerbates		 ISO RGD PMID:30312695 RGD:151660341 NCBI chr23:60,013,384...60,038,682
Ensembl chr23:60,014,046...60,037,997 		JBrowse link
G SPAG9 sperm associated antigen 9 ISO associated with Human Viral Hepatitis RGD PMID:29344208 RGD:30296654 NCBI chr16:42,224,565...42,384,160
Ensembl chr16:42,224,697...42,384,749 		JBrowse link
G SPC25 SPC25 component of NDC80 kinetochore complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:54,390,300...54,423,478
Ensembl chr10:54,403,157...54,423,245 		JBrowse link
G SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 ameliorates ISO human cells in mouse model RGD PMID:30710422 RGD:153344549 NCBI chr23:39,676,750...40,192,565
Ensembl chr23:39,676,558...39,965,037 		JBrowse link
G SPOP speckle type BTB/POZ protein exacerbates ISO mRNA:decreased expression:liver (human)
human cells in mouse model		 RGD PMID:26156804 PMID:33209975 RGD:11074965 RGD:153298924 NCBI chr16:69,990,554...70,073,241 JBrowse link
G SPP1 secreted phosphoprotein 1 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:16047475 PMID:35693827 RGD:153344586 RGD:1581375 NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407 		JBrowse link
G SPRTN SprT-like N-terminal domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25261934 NCBI chr25:68,599,377...68,620,568
Ensembl chr25:68,599,780...68,620,621 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase disease_progression ISO RGD PMID:9581679 RGD:150521543 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 PMID:21147110 NCBI chr16:16,847,603...16,874,239
Ensembl chr16:16,845,491...16,859,554 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr19:24,364,725...24,439,851
Ensembl chr19:24,364,911...24,440,014 		JBrowse link
G SRF serum response factor ISO RGD PMID:9570363 RGD:1581428 NCBI chr17:28,983,161...28,993,465
Ensembl chr17:28,983,002...28,992,995 		JBrowse link
G SRPX sushi repeat containing protein X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560
G SRSF1 serine and arginine rich splicing factor 1 ISO mRNA:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr16:35,392,573...35,396,815
Ensembl chr16:35,392,873...35,394,982 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 disease_progression
treatment		 ISO RGD PMID:28082404 PMID:29278882 PMID:32372053 RGD:150429663 RGD:150429666 RGD:150429692 NCBI chr16:44,945,193...44,948,496
Ensembl chr16:44,945,200...44,946,438 		JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 ISO protein:increased activity:liver: RGD PMID:9331085 RGD:10043141 NCBI chr15:81,205,121...81,346,089
Ensembl chr15:81,239,631...81,349,173 		JBrowse link
G STAB2 stabilin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:98,780,148...98,953,871
Ensembl chr11:98,779,921...98,954,913 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22488367 NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:liver (mouse) RGD PMID:28100771 RGD:127285675 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 susceptibility ISO Hepatitis B, Chronic; DNA:SNP: intron 3: (rs7574865) (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:23242368 PMID:26745093 RGD:11553302 NCBI chr10:76,553,626...76,708,540
Ensembl chr10:76,553,606...76,674,928 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A ameliorates ISO RGD PMID:28100771 RGD:127285675 NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026 		JBrowse link
G STC2 stanniocalcin 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr23:75,475,020...75,489,727
Ensembl chr23:75,475,022...75,488,678 		JBrowse link
G STIM1 stromal interaction molecule 1 ISO mRNA:increased expression:liver (human) RGD PMID:23211538 RGD:152995401 NCBI chr 1:62,651,472...62,865,992
Ensembl chr 1:62,651,290...62,865,986 		JBrowse link
G STMN1 stathmin 1 disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:28284560 PMID:28982915 RGD:21408578 NCBI chr20:106,866,719...106,873,314
Ensembl chr20:106,868,838...106,874,403 		JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr27:47,021,970...47,045,571
Ensembl chr27:47,021,965...47,045,223 		JBrowse link
G TAGLN2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr20:4,024,948...4,032,361
Ensembl chr20:4,024,775...4,032,526 		JBrowse link
G TALDO1 transaldolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chr 1:553,475...569,935
Ensembl chr 1:553,458...573,546 		JBrowse link
G TATDN1 TatD DNase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 8:119,055,356...119,103,328
Ensembl chr 8:119,052,415...119,102,839 		JBrowse link
G TBX3 T-box transcription factor 3 disease_progression
severity
ameliorates		 ISO protein:increased expression:liver (human)
human cells in mouse model		 RGD PMID:22811581 PMID:26922018 PMID:29295731 PMID:30578408 PMID:33577921 RGD:151361112 RGD:151361114 RGD:151361122 RGD:151361123 RGD:151361132 NCBI chr11:109,952,100...109,966,328
Ensembl chr11:109,952,054...109,965,065 		JBrowse link
G TCF19 transcription factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:41,310,999...41,319,268
Ensembl chr17:41,311,005...41,319,042 		JBrowse link
G TCIM transcriptional and immune response regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:38,146,171...38,147,526
Ensembl chr 8:38,146,241...38,146,561 		JBrowse link
G TEDC2 tubulin epsilon and delta complex 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:2,338,246...2,343,171
Ensembl chr 5:2,338,341...2,342,825 		JBrowse link
G TEP1 telomerase associated protein 1 susceptibility
disease_progression		 ISO DNA:SNP:intron:rs1760893(human)
associated with hepatitis B;DNA:SNPs: :rs1713449,rs1760898, rs872072 (human)		 RGD PMID:23907815 PMID:27305982 RGD:152975963 RGD:152977750 NCBI chr29:20,880,255...20,928,874
Ensembl chr29:20,883,678...20,923,313 		JBrowse link
G TERT telomerase reverse transcriptase no_association
disease_progression
susceptibility
treatment		 ISO associated with hepatitis B;DNA:SNP: :rs13167280 (human)
ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:SNPs::rs2736098(human)
DNA:mutations, polymorphisms:promoter,intron, exon:rs2736100,rs2736098(human)
DNA:mutations:promoter:
DNA:SNP,mutations:promoter:rs2853669 (-245T >C), (-124C > T),(-146C > T)human		 RGD
ClinVar		 PMID:17175353 PMID:19184104 PMID:23000435 PMID:23907815 PMID:25123086 More... RGD:11564803 RGD:14696767 RGD:14696768 RGD:14696769 RGD:14696770 RGD:150530496 RGD:152975963 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
G TET1 tet methylcytosine dioxygenase 1 ISO protein:decreased expression:liver RGD PMID:23671639 RGD:9586747 NCBI chr 9:62,709,800...62,843,322
Ensembl chr 9:62,712,484...62,837,138 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 ameliorates
disease_progression
severity		 ISO human cells in mouse model
mRNA:decreased expression:liver (human)
mRNA, protein:increased expression:liver (human)
mRNA, protein:decreased expression:liver (human)		 RGD PMID:26366235 PMID:29331390 PMID:30070373 PMID:33097695 RGD:150429595 RGD:150429597 RGD:150429684 RGD:150429689 NCBI chr 7:53,193,824...53,326,813
Ensembl chr 7:53,193,941...53,326,942 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17464989 PMID:28284560 NCBI chr21:55,134,921...55,139,862
Ensembl chr21:55,135,198...55,140,801 		JBrowse link
G TFRC transferrin receptor ISO mRNA:increased expression:liver RGD PMID:16953838 RGD:2292036 NCBI chr15:91,102,153...91,134,994
Ensembl chr15:91,102,817...91,135,584 		JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental		 CTD
RGD		 PMID:9029167 PMID:9060843 PMID:15565109 RGD:2317471 NCBI chr14:36,545,641...36,654,213
Ensembl chr14:36,545,875...36,648,237 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9029167 PMID:28100771 RGD:127285675 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr25:11,163,651...11,259,868
Ensembl chr25:11,163,100...11,258,470 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO mRNA, protein:decreased expression:liver RGD PMID:14585397 RGD:1601598 NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711 		JBrowse link
G TGM3 transglutaminase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:54,189,888...54,236,714
Ensembl chr 2:54,189,902...54,221,973 		JBrowse link
G TH tyrosine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:1,969,194...1,977,263
Ensembl chr 1:1,966,460...1,977,218 		JBrowse link
G THY1 Thy-1 cell surface antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:110,787,213...110,791,536
Ensembl chr 1:110,783,877...110,791,569 		JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr29:8,117,198...8,171,956 JBrowse link
G TIMD4 T cell immunoglobulin and mucin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:59,320,120...59,381,965
Ensembl chr23:59,319,749...59,355,100 		JBrowse link
G TK1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:70,186,103...70,200,689
Ensembl chr16:70,186,767...70,200,610 		JBrowse link
G TLR2 toll like receptor 2 susceptibility ISO associated with Hepatitis C, Chronic;DNA:deletion:promoter:-196 to -174(human) RGD PMID:21500195 PMID:22859216 PMID:27183918 RGD:15090813 RGD:15090815 RGD:18337266 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
G TLR3 toll like receptor 3 disease_progression ISO RGD PMID:23197495 RGD:21079421 NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232 		JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:SNP: :rs1057317(human)
DNA:SNPs, haplotype: :multiples
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver:		 RGD
CTD		 PMID:21559380 PMID:25179842 PMID:27022031 PMID:28578348 RGD:14700552 RGD:14700557 RGD:14700558 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TLR7 toll like receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24990399 NCBI chr  X:11,348,520...11,372,132 JBrowse link
G TMEM70 transmembrane protein 70 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr 8:69,576,786...69,582,478
Ensembl chr 8:69,576,808...69,583,308 		JBrowse link
G TNF tumor necrosis factor disease_progression ISO mRNA, protein:increased expression:liver, blood serum (mouse)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:26569409 PMID:26890368 PMID:27022031 RGD:11344640 RGD:14975171
G TNFAIP3 TNF alpha induced protein 3 sexual_dimorphism
ameliorates		 ISO mRNA,protein:increased expression:liver (human)
protein:decreased expression:liver (human)
mRNA:decreased expression:liver (human)		 RGD PMID:26538215 PMID:27253414 PMID:29190981 PMID:32015333 RGD:151347600 RGD:151347604 RGD:151347618 RGD:151347622 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:17326159 NCBI chr15:16,934,982...16,953,155
Ensembl chr15:16,934,962...16,954,860 		JBrowse link
G TNFSF9 TNF superfamily member 9 ISO RGD PMID:17325342 RGD:2317348 NCBI chr 6:6,131,157...6,136,345
Ensembl chr 6:6,131,571...6,135,463 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase disease_progression ISO protein:increased phosphorylation:liver, nucleus (human) RGD PMID:25160513 RGD:151347837 NCBI chr15:18,011,137...18,403,676
Ensembl chr15:18,011,170...18,399,981 		JBrowse link
G TONSL tonsoku like, DNA repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:138,641,514...138,657,429
Ensembl chr 8:138,641,575...138,656,673 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701 		JBrowse link
G TP53 tumor protein p53 treatment ISO ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA		 RGD
ClinVar
OMIM		 PMID:253702 PMID:960674 PMID:1349102 PMID:1349175 PMID:1359493 More... RGD:152998960 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G TP73 tumor protein p73 treatment
exacerbates		 ISO human cells in a mouse model
mRNA:increased expression:liver (human)
protein:decreased phosphorylation:liver (human)		 RGD PMID:14760085 PMID:19664633 PMID:25371988 PMID:27359056 PMID:31429776 RGD:151347579 RGD:151347592 RGD:151347593 RGD:151347594 RGD:151347596 NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691 		JBrowse link
G TPX2 TPX2 microtubule nucleation factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:36,131,907...36,191,254
Ensembl chr 2:36,134,760...36,191,425 		JBrowse link
G TRAF7 TNF receptor associated factor 7 treatment ISO mRNA:increased expression:liver RGD PMID:31730901 RGD:151356961 NCBI chr 5:2,051,247...2,072,763
Ensembl chr 5:2,059,349...2,071,297 		JBrowse link
G TRAIP TRAF interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:11,220,152...11,262,942
Ensembl chr22:11,233,996...11,262,830 		JBrowse link
G TRIM24 tripartite motif containing 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr21:107,166,180...107,291,897
Ensembl chr21:107,166,395...107,295,736 		JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:737,214...760,263
Ensembl chr 4:737,263...760,171 		JBrowse link
G TROAP trophinin associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:45,552,369...45,560,134
Ensembl chr11:45,553,251...45,560,123 		JBrowse link
G TSC1 TSC complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21499249 NCBI chr12:5,195,604...5,249,042
Ensembl chr12:5,195,675...5,244,157 		JBrowse link
G TSC2 TSC complex subunit 2 severity ISO protein:decreased expression:liver (human) RGD PMID:24119083 RGD:21079731 NCBI chr 5:1,946,534...1,985,168
Ensembl chr 5:1,946,927...1,987,682 		JBrowse link
G TSLP thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr23:14,419,820...14,423,331 JBrowse link
G TST thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr19:19,716,295...19,724,712
Ensembl chr19:19,716,180...19,724,589 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:109,912,976...109,917,097 JBrowse link
G TTK TTK protein kinase disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)		 CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr13:4,738,849...4,779,563
Ensembl chr13:4,738,959...4,780,627 		JBrowse link
G TTR transthyretin disease_progression ISO protein:decreased expression:blood serum (human)
protein:increased expression:blood serum (rat)
protein:increased expression:blood serum (human)		 RGD PMID:16240287 PMID:28876464 PMID:29534342 RGD:151356736 RGD:151664602 RGD:151665161 NCBI chr18:49,124,302...49,131,495
Ensembl chr18:49,124,121...49,131,399 		JBrowse link
G TXNIP thioredoxin interacting protein ISO OMIM:114550 MouseDO NCBI chr20:12,756,145...12,759,853
Ensembl chr20:12,756,053...12,761,177 		JBrowse link
G TYMS thymidylate synthetase susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:deletion:3'UTR:1494del6(human)		 CTD
RGD		 PMID:17659576 PMID:18019677 PMID:18230555 RGD:14696708 NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856 		JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats ISO OMIM:114550 MouseDO NCBI chr26:12,693,208...12,792,900
Ensembl chr26:12,749,774...12,795,279 		JBrowse link
G UBD ubiquitin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr17:43,061,243...43,065,135
Ensembl chr17:43,061,826...43,064,869 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:18,069,525...18,073,597 JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr25:27,069,971...27,084,360
Ensembl chr25:27,070,240...27,081,749 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 treatment ISO RGD PMID:32087767 RGD:151665344 NCBI chr 8:97,104,325...97,257,317
Ensembl chr 8:97,103,220...97,257,440 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18666234 NCBI chr27:9,074,961...9,086,606
Ensembl chr27:9,074,923...9,086,517 		JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:4,592,362...4,642,179
Ensembl chr 6:4,592,919...4,642,445 		JBrowse link
G UMPS uridine monophosphate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr22:56,081,897...56,097,164
Ensembl chr22:56,082,103...56,097,105 		JBrowse link
G UROC1 urocanate hydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:54,497,373...54,536,295
Ensembl chr22:54,499,487...54,535,862 		JBrowse link
G USP2 ubiquitin specific peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 1:110,733,097...110,760,119
Ensembl chr 1:110,734,737...110,742,186 		JBrowse link
G USP4 ubiquitin specific peptidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr22:10,672,920...10,735,374
Ensembl chr22:10,672,388...10,732,104 		JBrowse link
G VASN vasorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25826090 NCBI chr 5:4,052,239...4,063,884 JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO mRNA:decreased expression:liver RGD PMID:2064726 RGD:2306008 NCBI chr 6:6,337,255...6,415,851 JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr20:32,616,425...32,635,903
Ensembl chr20:32,615,333...32,635,862 		JBrowse link
G VDR vitamin D receptor susceptibility ISO associated with Hepatitis B, Chronic;DNA:SNP: :rs2228570(human)
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
associated with alcoholic liver cirrhosis;DNA:haplotype::		 RGD
ClinVar		 PMID:20572305 PMID:24033266 PMID:25541958 PMID:25741868 PMID:28492532 RGD:14402025 RGD:14402026 NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment
susceptibility
disease_progression		 ISO associated with liver cirrhosis;
protein:increased expression:serum:
DNA:SNP: :2578C>A (human)
associated with liver cirrhosis; protein:increased expression:platelet, liver:
protein:increased expression:liver
DNA:polymorphism:promoter:-2578C>A (rs699947)(human)		 RGD PMID:16835748 PMID:18392108 PMID:18544126 PMID:24445728 PMID:25999787 More... RGD:11527070 RGD:126848814 RGD:15003194 RGD:15003196 RGD:15003200 RGD:15014783 RGD:15036790 RGD:152177911 NCBI chr17:28,377,959...28,394,508 JBrowse link
G VEGFC vascular endothelial growth factor C ISO associated with liver cirrhosis; protein:increased expression:liver: RGD PMID:18544126 RGD:15003200 NCBI chr 7:122,772,539...122,893,486
Ensembl chr 7:122,772,182...122,893,512 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor disease_progression ISO RGD PMID:31321740 RGD:155882550 NCBI chr22:46,184,621...46,203,065
Ensembl chr22:46,184,756...46,204,428 		JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:3,950,129...3,984,849
Ensembl chr22:3,950,193...3,984,948 		JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:55,963,007...55,982,929
Ensembl chr  X:55,962,866...55,981,287 		JBrowse link
G WDR62 WD repeat domain 62 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:30,964,219...31,010,692
Ensembl chr 6:30,964,319...31,011,403 		JBrowse link
G WDR76 WD repeat domain 76 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr26:39,178,407...39,222,005
Ensembl chr26:39,176,535...39,223,993 		JBrowse link
G WNT2 Wnt family member 2 susceptibility ISO associated with hepatitis B;DNA:SNP: :rs4730775(human) RGD PMID:28328801 RGD:14402040 NCBI chr21:85,955,517...86,005,664
Ensembl chr21:85,955,145...86,001,730 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 ISO RNA:increased expression:liver: RGD PMID:26551349 RGD:11096781 NCBI chr16:7,065,531...7,085,590
Ensembl chr16:7,066,333...7,085,625 		JBrowse link
G XDH xanthine dehydrogenase ISO protein:decreased activity:tumor (rat) RGD PMID:179860 RGD:5135059 NCBI chr14:76,084,693...76,162,840
Ensembl chr14:76,085,368...76,163,936 		JBrowse link
G XPO1 exportin 1 ameliorates
exacerbates
treatment		 ISO human cell line in a mouse model
mRNA:increased expression:liver (human)		 RGD PMID:25030088 PMID:27013579 PMID:31371628 RGD:151665796 RGD:151667433 RGD:151667441 NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723 		JBrowse link
G XPO5 exportin 5 severity ISO DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:24676133 RGD:11041737 NCBI chr17:28,585,317...28,637,045
Ensembl chr17:28,585,536...28,635,519 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
severity
disease_progression
no_association		 ISO DNA:missense mutation:cds:p.R399Q (rs25487) (human)
DNA:SNPs:exon 9, exon 15: c.910A>G, c.1686C>G (human)
associated with Chronic Hepatitis C;DNA:SNP:exon 14: c.1517G>C, p.506G>A (human)
DNA:SNP:exon 13: c.1471G>A, p.E491K (human)
DNA:SNPs:cds: 194C>T, 280A>G (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R399Q (human)
associated with hepatitis B;DNA:missense mutation, haplotype:cds:p.R399Q (human)
DNA:SNPs:exons:c.1254C>T, c.1517G>C (human)
DNA:silent mutation, missense mutation:cds:c.1161G>A, c.1779C>G (p.L387L, p.S593R) (human)
DNA:missense mutations:cds:c.482C>T, c.1178G>A (p.P161L, p.R393H) (human)
DNA:missense mutation:cds:c.1804C>A (p.G506A) (human)
DNA:missense mutation:cds:p.R399Q (28152G>A) (rs25487) (human)
DNA:missense mutations:cds:p.R194W, p.R280H, p.R399Q (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R194W (human)		 RGD PMID:14519756 PMID:19194663 PMID:22502666 PMID:23454624 PMID:23493666 More... RGD:14696702 RGD:14696772 RGD:14696773 RGD:14985238 RGD:14985240 RGD:14985242 RGD:14985243 RGD:15014789 RGD:15014790 RGD:15014791 RGD:15014792 RGD:15036794 RGD:15036797 RGD:150530503 RGD:150530624 RGD:150540332 RGD:150540333 NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29698666 NCBI chr 1:93,479,478...93,605,340
Ensembl chr 1:93,479,135...93,606,808 		JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28104805 NCBI chr20:104,041,657...104,078,705
Ensembl chr20:104,040,679...104,078,484 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta severity ISO RGD PMID:27811373 RGD:14700875 NCBI chr 8:95,786,197...95,821,270
Ensembl chr 8:95,788,305...95,819,197 		JBrowse link
G ZC3H12D zinc finger CCCH-type containing 12D ISO CTD Direct Evidence: marker/mechanism CTD PMID:34545456 NCBI chr13:22,152,938...22,195,470
Ensembl chr13:22,158,259...22,194,514 		JBrowse link
G ZFHX3 zinc finger homeobox 3 disease_progression
severity		 ISO associated with Chronic Hepatitis B;protein:decreased expression:blood serum (human)
human cell line in a mouse model		 RGD PMID:20534899 PMID:32277050 RGD:151361162 RGD:151361169 NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112 		JBrowse link
G ZFP36 ZFP36 ring finger protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:34,011,073...34,013,665
Ensembl chr 6:34,011,031...34,013,870 		JBrowse link
G ZIC2 Zic family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:78,631,556...78,637,422
Ensembl chr 3:78,631,530...78,636,548 		JBrowse link
G ZIC4 Zic family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:43,285,711...43,309,197
Ensembl chr15:43,291,014...43,309,187 		JBrowse link
G ZIC5 Zic family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:78,611,133...78,629,616
Ensembl chr 3:78,615,177...78,621,446 		JBrowse link
G ZNF23 zinc finger protein 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21965783 NCBI chr 5:54,578,420...54,609,302 JBrowse link
G ZWINT ZW10 interacting kinetochore protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:74,912,070...74,915,920
Ensembl chr 9:74,912,093...74,915,926 		JBrowse link
hepatocellular clear cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO DNA:polymorphism: :rs12478635(human)
DNA:misssense mutation:cds:p.Arg132Cys(human)		 RGD PMID:25355558 PMID:28403884 RGD:14974227 RGD:14974228 NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975 		JBrowse link
G LEP leptin ISO mRNA:increased expression:liver: RGD PMID:20723213 RGD:14696785 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G LEPR leptin receptor ISO mRNA:increased expression:liver RGD PMID:20723213 RGD:14696785 NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229 		JBrowse link
G LOC103231165 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO DNA:polymorphism: :rs11632348(human) RGD PMID:25355558 RGD:14974228 NCBI chr29:8,633,429...8,650,744
Ensembl chr29:8,633,715...8,650,657 		JBrowse link
G TERT telomerase reverse transcriptase disease_progression ISO mRNA:increased expression:liver: RGD PMID:20723213 PMID:28460432 RGD:14696783 RGD:14696785 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
liver benign neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B ISO protein:increased activity:liver (rat) RGD PMID:8264573 RGD:2313432 NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258 		JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO RGD PMID:9633945 RGD:10755510 NCBI chr11:7,696,571...7,700,424
Ensembl chr11:7,696,259...7,700,643 		JBrowse link
G CBX7 chromobox 7 ISO RGD PMID:22214847 RGD:9587356 NCBI chr19:21,776,618...21,798,525
Ensembl chr19:21,775,931...21,798,309 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:increased expression:liver RGD PMID:23890812 RGD:13792775 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342 		JBrowse link
G COL1A1 collagen type I alpha 1 chain onset ISO mRNA:increased expression:liver (rat) RGD PMID:21295105 RGD:5130894 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G EIF4G2 eukaryotic translation initiation factor 4 gamma 2 ISO RGD PMID:9633945 RGD:10755510 NCBI chr 1:54,017,587...54,029,491
Ensembl chr 1:54,017,696...54,028,843 		JBrowse link
G H2AFX histone H2AX treatment ISO RGD PMID:23474136 RGD:8693737 NCBI chr 1:110,466,692...110,468,776
Ensembl chr 1:110,467,775...110,468,206 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:liver (rat) RGD PMID:22213170 RGD:5686872 NCBI chr23:35,862,817...35,917,490
Ensembl chr23:35,862,814...35,918,287 		JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:25168696 RGD:11049493 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836 		JBrowse link
G KMT5C lysine methyltransferase 5C disease_progression ISO protein:decreased expression:liver RGD PMID:16497704 RGD:9586726 NCBI chr 6:47,942,100...47,950,364
Ensembl chr 6:47,944,197...47,949,693 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 ISO RGD PMID:24233520 RGD:7495808 NCBI chr16:19,396,377...19,427,617
Ensembl chr16:19,396,452...19,427,652 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase onset ISO mRNA, protein:increased expression:neoplastic liver (rat) RGD PMID:11956651 RGD:2317546 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase onset ISO mRNA:decreased expression:liver (rat) RGD PMID:22213190 RGD:6893663 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:24418717 RGD:11035219 NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599 		JBrowse link
G TTPA alpha tocopherol transfer protein ISO mRNA:decreased expression:liver RGD PMID:9178827 RGD:1600436 NCBI chr 8:58,952,685...58,979,083
Ensembl chr 8:58,950,626...58,978,258 		JBrowse link
G TUT4 terminal uridylyl transferase 4 ISO human cells in a mouse model RGD PMID:24056962 RGD:11530012 NCBI chr20:80,395,484...80,522,442
Ensembl chr20:80,395,581...80,523,671 		JBrowse link
liver cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 severity ISO mRNA:decreased expression:liver (mouse) RGD PMID:30580964 RGD:24922199 NCBI chr12:34,587,123...34,734,936
Ensembl chr12:34,587,118...34,731,642 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 ISO mRNA:decreased expression:liver RGD PMID:29651702 RGD:14402411 NCBI chr10:54,458,283...54,575,943
Ensembl chr10:54,459,377...54,575,059 		JBrowse link
G ACOT12 acyl-CoA thioesterase 12 ISO RGD PMID:2566591 RGD:13831129 NCBI chr 4:75,398,361...75,543,933
Ensembl chr 4:75,469,424...75,535,267 		JBrowse link
G ADAM28 ADAM metallopeptidase domain 28 ISO mRNA:increased expression:liver RGD PMID:32782619 RGD:153297784 NCBI chr 8:22,424,260...22,483,878
Ensembl chr 8:22,430,579...22,488,257 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO DNA:missense mutation:cds:p.E487K (mouse) RGD PMID:26150517 RGD:14696779 NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374 		JBrowse link
G ATM ATM serine/threonine kinase ameliorates ISO RGD PMID:19919837 RGD:150340702 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520 		JBrowse link
G CCND1 cyclin D1 disease_progression ISO protein:increased expression:liver (rat) RGD PMID:11797828 RGD:151356973 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CCND2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661 		JBrowse link
G CCNE1 cyclin E1 disease_progression ISO protein:increased expression:liver (rat) RGD PMID:11797828 RGD:151356973 NCBI chr 6:24,879,923...24,888,985 JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO human cells in mouse model RGD PMID:27367027 RGD:153305911 NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700 		JBrowse link
G GPT glutamic--pyruvic transaminase treatment ISO RGD PMID:22922605 RGD:14975251 NCBI chr 8:138,716,802...138,721,421
Ensembl chr 8:138,718,767...138,721,251 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 treatment ISO RGD PMID:22922605 RGD:14975251 NCBI chr 5:32,743,850...32,791,299
Ensembl chr 5:32,744,065...32,791,479 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO DNA:missense mutations:cds:p.Q61L, p.Q61K, p.Q61R (mouse) RGD PMID:9142214 RGD:14688053 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO human cells in mouse model RGD PMID:27367027 RGD:153305911 NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO human cells in mouse model RGD PMID:27367027 RGD:153305911 NCBI chr  X:128,781,975...128,816,039
Ensembl chr  X:128,787,785...128,806,083 		JBrowse link
G IL10 interleukin 10 ISO RGD PMID:30610790 RGD:14975253 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 treatment ISO miRNA:decreased expression:liver RGD PMID:25311838 RGD:14694834 NCBI chr 2:27,484,699...27,521,108
Ensembl chr 2:27,484,760...27,522,504 		JBrowse link
G JAK2 Janus kinase 2 severity ISO human cell line in a mouse model RGD PMID:27788478 RGD:18182929 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G KRT18 keratin 18 severity ISO associated with fatty liver disease RGD PMID:27689336 RGD:18337485 NCBI chr11:49,073,733...49,081,706 JBrowse link
G LOC103233018 liver carboxylesterase 1 treatment ISO RGD PMID:27523631 RGD:152995275 NCBI chr 5:41,710,500...41,745,483 JBrowse link
G LOC103233229 cadherin-1 ISO mRNA:increased expression:liver (mouse) RGD PMID:25319454 RGD:152995431 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 exacerbates ISO RGD PMID:17468757 RGD:151665350 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G PCNA proliferating cell nuclear antigen disease_progression ISO protein:increased expression:liver (rat) RGD PMID:11797828 RGD:151356973 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha susceptibility ISO RGD PMID:20583210 RGD:14402407 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISO protein:decreased expression:liver (human) RGD PMID:26172293 RGD:11530741 NCBI chr22:8,421,178...8,567,221
Ensembl chr22:8,420,960...8,567,201 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:21625523 RGD:152995425 NCBI chr11:20,992,353...21,091,761
Ensembl chr11:21,001,655...21,093,278 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 ISO mRNA:decreased expression:liver (mouse) RGD PMID:25319454 RGD:152995431 NCBI chr11:20,637,429...20,760,577
Ensembl chr11:20,648,582...20,761,161 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 disease_progression ISO mRNA:decreased expression:liver (human) RGD PMID:21625523 RGD:152995425 NCBI chr 1:66,375,924...66,430,804
Ensembl chr 1:66,376,299...66,433,055 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 severity ISO mRNA:increased expression:liver (human) RGD PMID:30088263 RGD:15036795 NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094 		JBrowse link
liver carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7B ATPase copper transporting beta ISO RGD PMID:11509115 RGD:1302456 NCBI chr 3:29,817,712...29,899,302
Ensembl chr 3:29,816,860...29,899,077 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO DNA:deletion:exons: RGD PMID:24293323 RGD:150429711 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674 		JBrowse link
G HMBS hydroxymethylbilane synthase sexual_dimorphism ISO Protein:increased activity:liver (rat) RGD PMID:1781034 RGD:25440495 NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO DNA:hypomethylation RGD PMID:3345576 RGD:14694848 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G IL10 interleukin 10 ISO DNA:SNP:promoter:-592C>A (rs1800872) (human) RGD PMID:28763918 RGD:14975157 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO mRNA:increased expression:liver (human) RGD PMID:3018923 RGD:14975106 NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G PDCD10 programmed cell death 10 ISO protein:increased expression:liver (human) RGD PMID:32186778 RGD:401827111 NCBI chr15:21,697,366...21,748,760
Ensembl chr15:21,706,675...21,749,470 		JBrowse link
Liver Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase severity ISO associated with skin melanoma;DNA:missense mutations:cds:
associated with colorectal cancer;DNA:missense mutations:cds:pV599E,p.V600E (human)
associated with colorectal cancer;DNA:mutation:cds:
associated with colorectal cancer;DNA:missense mutation:cds:p.V600E (human)
associated with colorectal cancer;DNA:mutations:multiple		 RGD PMID:22331825 PMID:23010994 PMID:26775732 PMID:27737491 PMID:28787433 RGD:11554843 RGD:14696791 RGD:15039394 RGD:18337264 RGD:18337265 NCBI chr21:109,495,525...109,690,261 JBrowse link
G CCL2 C-C motif chemokine ligand 2 disease_progression ISO associated with colorectal cancer RGD PMID:27058904 RGD:14995463 NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 treatment ISO associated with Animal Mammary Neoplasms; RGD PMID:15692764 RGD:14995455 NCBI chr16:29,351,214...29,361,317 JBrowse link
G CCND2 cyclin D2 ISO associated with colorectal cancer;protein:increased expression:colorectum RGD PMID:19508551 RGD:151665111 NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661 		JBrowse link
G CD44 CD44 molecule (IN blood group) ISO associated with Breast Neoplasm;protein:increased expression:liver RGD PMID:17991717 RGD:2289349 NCBI chr 1:30,039,854...30,132,646
Ensembl chr 1:30,039,749...30,132,416 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ameliorates ISO associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment ISO associated with colon carcinoma; RGD PMID:30381616 RGD:27095891 NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ameliorates ISO associated with colorectal cancer; human cells in mouse model RGD PMID:30789971 RGD:151893289 NCBI chr 9:40,005,580...40,020,513
Ensembl chr 9:40,011,439...40,020,494 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO associated with colorectal cancer; human colon adenocarcinoma cells in a mouse model RGD PMID:29679563 RGD:26884358 NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ameliorates ISO associated with colorectal cancer; human cells in mouse model
human cells in mouse model; associated with colorectal cancer		 RGD PMID:29436696 PMID:30789971 RGD:151893289 RGD:152023643 NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309 		JBrowse link
G DAXX death domain associated protein exacerbates ISO associated with pancreatic endocrine carcinoma;DNA:mutations:CDS:multiple (human)
associated with colon cancer; mRNA:decreased expression:liver (human)
associated with neuroendocrine tumor;DNA:mutations:CDS:multiple (human)		 RGD PMID:30339629 PMID:30342802 PMID:31942198 RGD:152025194 RGD:152025199 RGD:152025203 NCBI chr17:38,754,227...38,758,714
Ensembl chr17:38,754,280...38,759,071 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 treatment ISO human cells in mouse model; nilotinib
mRNA:increased expression:liver (mouse)		 RGD PMID:29438985 PMID:30666650 PMID:33110221 RGD:151347537 RGD:151347685 RGD:151347840 NCBI chr17:41,564,271...41,583,404
Ensembl chr17:41,564,992...41,575,682 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO associated with colon carcinoma
associated with melanoma;		 RGD PMID:21701781 PMID:22071959 RGD:150429701 RGD:150429713 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674 		JBrowse link
G DOCK6 dedicator of cytokinesis 6 ameliorates ISO associated with stomach cancer; RGD PMID:29587866 RGD:155791564 NCBI chr 6:10,133,688...10,191,995 JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 disease_progression ISO associated with colorectal cancer; RGD PMID:28846828 RGD:21408566 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO associated with colorectal cancer;mRNA:increased expression:colorectal mucosa: RGD PMID:19082464 RGD:25330357 NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO human cells in mouse model RGD PMID:30114390 RGD:153344554 NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373 		JBrowse link
G GPC3 glypican 3 ISO protein:increased expression:blood serum (human) RGD PMID:28801286 RGD:243065135 NCBI chr  X:108,688,706...109,143,653 JBrowse link
G HMBS hydroxymethylbilane synthase ISO associated with colon adenocarcinoma;protein:decreased activity:liver(rat) RGD PMID:1386052 RGD:25440496 NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095 		JBrowse link
G IL2 interleukin 2 treatment ISO associated with Colorectal Neoplasms, Carcinoma, Hepatocellular;
associated with colon carcinoma		 RGD PMID:9354462 PMID:11591892 RGD:14928215 RGD:8663446 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969 		JBrowse link
G IQSEC1 IQ motif and Sec7 domain ArfGEF 1 ISO human cells in mouse model RGD PMID:22662237 RGD:153344589 NCBI chr22:48,873,240...49,050,666
Ensembl chr22:48,872,925...49,050,625 		JBrowse link
G LOC103244924 cyclin-G1 treatment ISO human cells in mouse model RGD PMID:10910035 RGD:151356987 NCBI chr23:65,709,759...65,716,913
Ensembl chr23:65,709,786...65,714,711 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO associated with colon cancer;protein:increased expression:colon (human) RGD PMID:24533778 RGD:155259116 NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398 		JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor exacerbates
severity		 ISO associated with pancreatic ductal adenocarcinoma; human cells in mouse model
associated with pancreatic cancer; protein:increased expression:liver, pancreas (human)
associated with colorectal carcinoma;protein:increased expression:colorectum (human)		 RGD PMID:23747337 PMID:30770989 RGD:126925751 RGD:126925752 NCBI chr20:89,457,549...89,474,756
Ensembl chr20:89,459,493...89,474,352 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase susceptibility ISO associated with melanoma;DNA:mutations: exons (human)
human gene in a mouse model;DNA:missense mutations:cds:p.G12V, p.Q61K (human)
associated with colorectal cancer;DNA:mutations:exons (human)		 RGD PMID:26799184 PMID:28011498 PMID:28787433 RGD:14696774 RGD:14696791 RGD:14696792 NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B treatment ISO mouse tumor cells in mouse recipient RGD PMID:31348125 RGD:151660353 NCBI chr11:66,095,445...66,222,402
Ensembl chr11:66,101,038...66,221,982 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:30404068 RGD:152995463 NCBI chr 4:37,758,531...37,885,323
Ensembl chr 4:37,762,901...37,873,766 		JBrowse link
G RNF43 ring finger protein 43 ISO associated with colorectal adenocarcinoma;mRNA:increased expression:liver (human) RGD PMID:28789449 RGD:151361221 NCBI chr16:34,981,126...35,046,478
Ensembl chr16:34,980,922...35,045,107 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 severity ISO associated with colon adenocarcinoma RGD PMID:11745822 RGD:151361130 NCBI chr 1:11,011,351...11,050,494
Ensembl chr 1:11,008,120...11,050,298 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 severity ISO associated with colon cancer
associated with colon adenocarcinoma		 RGD PMID:11718450 PMID:11745822 RGD:151361129 RGD:151361130 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
G SMAD4 SMAD family member 4 treatment ISO associated with colorectal carcinoma; DNA:mutations: :
associated with colorectal carcinoma;protein:decreased expression:colorectum:		 RGD PMID:17390050 PMID:29551247 RGD:18937000 RGD:21066338 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478 		JBrowse link
G SOX30 SRY-box transcription factor 30 ameliorates ISO RGD PMID:29739711 RGD:151660333 NCBI chr23:60,013,384...60,038,682
Ensembl chr23:60,014,046...60,037,997 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase disease_progression ISO associated with colon cancer;protein:increased activity:colon RGD PMID:7678609 RGD:150521542 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO associated with colorectal carcinoma;mRNA,protein:increased expression:liver: RGD PMID:22156924 RGD:15014782 NCBI chr17:28,377,959...28,394,508 JBrowse link
mixed fibrolamellar hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKACA protein kinase cAMP-activated catalytic subunit alpha susceptibility ISO RGD PMID:28923495 RGD:151347843 NCBI chr 6:12,743,752...12,759,155 JBrowse link
Ruijs-Aalfs syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPRTN SprT-like N-terminal domain ISO ClinVar Annotator: match by term: Progeroid features-hepatocellular carcinoma predisposition syndrome | ClinVar Annotator: match by term: Ruijs-Aalfs syndrome OMIM
ClinVar		 PMID:12503110 PMID:25261934 PMID:25741868 NCBI chr25:68,599,377...68,620,568
Ensembl chr25:68,599,780...68,620,621 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15388
    disease of cellular proliferation 7341
      Neoplasms by Site 6819
        Liver Neoplasms 1054
          Experimental Liver Neoplasms 109
          liver benign neoplasm + 33
          liver cancer + 921
Path 2
Term Annotations click to browse term
  disease 15388
    disease of anatomical entity 15074
      gastrointestinal system disease 6448
        hepatobiliary disease 2805
          liver disease 2703
            Liver Neoplasms 1054
              Experimental Liver Neoplasms 109
              liver benign neoplasm + 33
              liver cancer + 921
paths to the root