CCL13 (C-C motif chemokine ligand 13)

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Gene: CCL13 (C-C motif chemokine ligand 13) Chlorocebus sabaeus

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Symbol:

CCL13

Name:

C-C motif chemokine ligand 13

RGD ID:

18785567

Description:

ENCODES a protein that exhibits CCR2 chemokine receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); monocyte chemotaxis (ortholog); negative regulation of leukocyte proliferation (ortholog); ASSOCIATED WITH allergic disease (ortholog); brain ischemia (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

C-C motif chemokine 13

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	27,864,260 - 27,867,457 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	27,865,318 - 27,867,415 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	2,152,140 - 2,154,842 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

allergic disease (ISO)

brain ischemia (ISO)

Bronchial Hyperreactivity (ISO)

hepatocellular carcinoma (ISO)

idiopathic pulmonary fibrosis (ISO)

multiple sclerosis (ISO)

Neurodevelopmental Disorders (ISO)

pneumonia (ISO)

Spinal Cord Injuries (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (ISO)

antimicrobial humoral immune response mediated by antimicrobial peptide (IEA)

chemokine-mediated signaling pathway (IEA)

chemotaxis (IEA)

cytoskeleton organization (IEA)

eosinophil chemotaxis (IEA)

immune response (IEA)

inflammatory response (IEA)

killing of cells of another organism (IEA)

monocyte chemotaxis (ISO)

negative regulation of leukocyte proliferation (ISO)

positive regulation of cell migration (IEA)

positive regulation of leukocyte migration (ISO)

regulation of cell shape (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

Molecular Function

CCR chemokine receptor binding (IEA)

CCR2 chemokine receptor binding (ISO)

chemokine activity (IEA)

cytokine activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CCL13
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	27,864,260 - 27,867,457 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	27,865,318 - 27,867,415 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	2,152,140 - 2,154,842 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CCL13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	34,356,480 - 34,358,610 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	34,356,480 - 34,358,610 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	32,683,499 - 32,685,629 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	29,707,584 - 29,709,742 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	29,707,583 - 29,709,741	NCBI
Celera	17	29,593,701 - 29,595,859 (+)	NCBI		Celera
Cytogenetic Map	17	q12	NCBI
HuRef	17	28,869,568 - 28,871,726 (+)	NCBI		HuRef
CHM1_1	17	32,747,735 - 32,749,893 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	35,303,463 - 35,305,593 (+)	NCBI		T2T-CHM13v2.0

Ccl12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	81,992,671 - 81,994,225 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	81,992,671 - 81,994,226 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	82,101,845 - 82,103,399 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	82,101,845 - 82,103,400 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	81,915,347 - 81,916,901 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	81,918,073 - 81,919,486 (+)	NCBI		MGSCv36	mm8
Celera	11	86,814,429 - 86,815,983 (+)	NCBI		Celera
Cytogenetic Map	11	C	NCBI
cM Map	11	49.9	NCBI

Ccl12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	67,567,876 - 67,569,426 (+)	NCBI		GRCr8
mRatBN7.2	10	67,070,230 - 67,071,780 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	67,070,230 - 67,071,780 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	71,691,474 - 71,693,024 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	71,196,825 - 71,198,375 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	66,657,944 - 66,659,494 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	69,476,866 - 69,478,416 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	69,476,775 - 69,478,462 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	69,111,876 - 69,113,426 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	70,321,036 - 70,322,586	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	66,017,637 - 66,019,187 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

CCL13
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	30,110,619 - 30,120,918 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	31,991,689 - 32,002,241 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	22,430,633 - 22,432,893 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	22,724,145 - 22,726,306 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	22,723,888 - 22,726,381 (-)	Ensembl	panpan1.1		panPan2

CCL13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	38,938,944 - 38,940,231 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	38,938,135 - 38,940,231 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	38,162,012 - 38,163,300 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	39,752,155 - 39,753,443 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	39,728,462 - 39,769,550 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	38,539,350 - 38,540,637 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	38,818,831 - 38,820,119 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	38,907,308 - 38,908,596 (-)	NCBI		UU_Cfam_GSD_1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
61	34	17	32	32	46	19

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008011015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000004387 ⟹ ENSCSAP00000002645

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	27,865,318 - 27,867,415 (+)	Ensembl

RefSeq Acc Id:

XM_008011015 ⟹ XP_008009206

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	27,864,260 - 27,867,457 (+)	NCBI
Vero_WHO_p1.0	NW_023666075	2,152,140 - 2,154,842 (-)	NCBI

Sequence:

show sequence

TTCCTATTTCTCTAATCCTAGCTGTTTATTTCTTCCCTTTACTTTCCCTGGGCTTATTTTGCTA
GAGTGGAATGCAGAGGGATGAGTGTTCCAGGAAGGCACAAAAATTGTGCCAAGTCTTGGAGCTA
GGGATGAGTGGGGAAGGGACATGTTCAACCATTCTAAGCCATTCCCTTCCCAACTCCCAGCTCC
CAGGTATGTGCCCCTCGCAGGAAGAGCCCAGGAATGGGCCAAACACCTCACTTCTTTGCTCTGA
GGACCACCCCAACCCTCCCATCAACAGCTCCAGAAACCCAATGGTCCTTCCTGGAAACAGGGGG
CTCGCATCAGTCAGAAATGTTTGAACCATGTCCCTCTGGGCCTGAGGGGCAGAAGGGGTCATAT
TATGGAATGTAAGGAGGCCCTGTCATCAGAACCTGACTTAATCTGTTTCAGATATTAGACTTCC
ACATAAAAGTTGACTGGAAAAAGACTTCTGCAGCTAAACGAAAGTTTAAAACTACCTTGGTGAT
AAAATATAAGCAGACTAGCTTTCTCTTCTAGCTTTCCTACTCATTTCCCAGAAGACTTTGGTCA
AGTTATTTAATCTCTCTGCATCCATTTCCTCATCTATGAAATGGGCATGATCATAATGGTACGT
ACCTCCTCAAACTAAATATATAACATGAACAGAGTCCTTAGCATAGCCCTCTTTTCTCTACAGG
AGTTAATTTTCATTGTTTTTCTTTTTTCTGCTAGAGAAAGTAAGCAGAAAACAGCTCCTTGGAC
GGCTTCCCATGGTGAGTGGCGGGGCACATCTGTGTCCCTTTTTCCTCCCTGGCTCCTTGTGGCC
TGGACAGCCAGAAGGAAGCCATGCCATGCTGCTTCAGCCCTCAGCTTCCCTCTTGCATTTCCTG
AAAAAGTTTTTGGTGCCCAGCTCCAGCTCAGCAGATTCAGGATCCCCCTTCATCATGACTTGGT
CAACACCCTACTCAGGCCAAGGTCCTCTGAGAGCTCCAAGCCTCCCCACTCCCTATAAAAGGCA
GGCAGAACAGCCAGAGGAGCAGAGAGGCAAAGGAACATTGTGAAATCTCCAACTCTTACCCTTC
AACATGAAAGTCTCTGCAGCGCTTCTGTGCCTGCTGCTTATAACAGTAGCTTTCAATCCCCAGG
GACTTGCTCAGCCAGATGCACTCAACGTCCCATCCACTTGCTGCTTCACATTTAGCAGTAAGAA
GATCTCCTTGCAGAGGCTGAAGAGCTATCGCATCACCACCAGCCGGTGTCCCCAGAAGGCTGTC
ATCTTCAGAACCAAACTGGGCAAGGAGATGTGTGCTGACCCAAAGGAGAAGTGGGTCCAGAATT
GTATGAAGCACCTGGGCCAGAAAGCTCACACGCTGAAGACTTGAACTCTCCTACCCCCACTGAA
ATCAAGTGGGAGTATGTGAAATGACTTTTCCATTCTCCTCCGGCCTCCTCTTCTATACTTTGGA
ATATTTCTACCATAATTTTCAAATAGAATGCATTCTGTTTTGTGATTGAAAATGTACTATGTGT
TAAGTAATATTGGCTATTATATGACTTGTTGCTGGTTTGGAGTTTATTTGAGTATTGGTGATCT
TTTTTAAAGCAAGGCGTTGAGCAAGTTGGTTGCTGTCTGTAAGCCCCCTTCCCTTCCACTGTGA
GCTGCTAGCAGTGGGTTTCTGTTCGGCTCCCAGAGGTTGAGAGCGTGCCTGTGGGAGTCATGGA
CATGAAGGGATGCTGCAATGTTGGGAGGCAATGCATCCTCCCAATGTAGGGAGGTGAATGTGAG
GCATTGCTAAATATGTTATTGTGGAAAGATGAATGCAATGGTAGGACTGCTGACATTTTACAGA
AAATACACTTTATTTAAAATCTCTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008009206	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002645
	ENSCSAP00000002645.1

RefSeq Acc Id:	XP_008009206 ⟸ XM_008011015
- UniProtKB:	A0A0D9R206 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000002645 ⟸ ENSCSAT00000004387

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000006348	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004387.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.40	UniProtKB/TrEMBL
InterPro	Chemokine_b/g/d	UniProtKB/TrEMBL
	Chemokine_CC_CS	UniProtKB/TrEMBL
	Chemokine_IL8-like_dom	UniProtKB/TrEMBL
	Interleukin_8-like_sf	UniProtKB/TrEMBL
KEGG Report	csab:103242714	UniProtKB/TrEMBL
NCBI Gene	CCL13	ENTREZGENE
PANTHER	C-C MOTIF CHEMOKINE 13	UniProtKB/TrEMBL
	PTHR12015	UniProtKB/TrEMBL
Pfam	IL8	UniProtKB/TrEMBL
PRINTS	FRACTALKINE	UniProtKB/TrEMBL
PROSITE	SMALL_CYTOKINES_CC	UniProtKB/TrEMBL
SMART	SCY	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54117	UniProtKB/TrEMBL
UniProt	A0A0D9R206	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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