BBC3 (BCL2 binding component 3) - Rat Genome Database

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Gene: BBC3 (BCL2 binding component 3) Chlorocebus sabaeus
Analyze
Symbol: BBC3
Name: BCL2 binding component 3
RGD ID: 18726720
Description: ENCODES a protein that exhibits ATPase binding (ortholog); INVOLVED IN apoptotic process (ortholog); apoptotic signaling pathway (ortholog); cellular response to ionizing radiation (ortholog); PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH brain ischemia (ortholog); Burkitt lymphoma (ortholog); Esophageal Neoplasms (ortholog); FOUND IN lysosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bcl-2-binding component 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,560,550 - 40,572,428 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,561,274 - 40,567,853 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607320,284,513 - 20,296,281 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
lysosome  (ISO)
mitochondrion  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202   PMID:34202551  


Genomics

Comparative Map Data
BBC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,560,550 - 40,572,428 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,561,274 - 40,567,853 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607320,284,513 - 20,296,281 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BBC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381947,220,824 - 47,232,860 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1947,220,822 - 47,232,766 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,724,081 - 47,735,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361952,415,924 - 52,426,291 (-)NCBINCBI36Build 36hg18NCBI36
Build 341952,415,923 - 52,426,291NCBI
Celera1944,527,934 - 44,539,878 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1944,148,994 - 44,171,276 (-)NCBIHuRef
CHM1_11947,726,482 - 47,738,433 (-)NCBICHM1_1
T2T-CHM13v2.01950,046,144 - 50,058,334 (-)NCBIT2T-CHM13v2.0
Bbc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,042,307 - 16,052,130 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,042,318 - 16,052,130 (+)EnsemblGRCm39 Ensembl
GRCm38716,308,398 - 16,318,334 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,308,393 - 16,318,205 (+)EnsemblGRCm38mm10GRCm38
MGSCv37716,894,932 - 16,903,683 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,468,160 - 15,476,856 (+)NCBIMGSCv36mm8
Celera713,504,637 - 13,513,389 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map78.85NCBI
Bbc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,141,450 - 86,150,666 (+)NCBIGRCr8
mRatBN7.2177,013,281 - 77,022,509 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,014,543 - 77,022,509 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,388,489 - 82,396,486 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0190,952,521 - 90,960,521 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,143,587 - 84,151,585 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,261,491 - 78,267,802 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0179,520,749 - 79,521,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera171,503,438 - 71,511,180 (+)NCBICelera
Cytogenetic Map1q21NCBI
Bbc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555741,167,242 - 1,174,966 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555741,167,790 - 1,174,966 (-)NCBIChiLan1.0ChiLan1.0
BBC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22053,361,167 - 53,374,027 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11955,232,535 - 55,245,609 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01944,203,517 - 44,215,860 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,727,826 - 52,738,535 (-)NCBIpanpan1.1PanPan1.1panPan2
BBC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11108,742,793 - 108,750,832 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1108,741,713 - 108,749,946 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,222,131 - 108,231,165 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,267,089 - 109,276,129 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,271,046 - 109,275,144 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11108,934,859 - 108,943,893 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01108,578,770 - 108,587,804 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,447,382 - 109,456,419 (+)NCBIUU_Cfam_GSD_1.0
Bbc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934919,343,021 - 19,354,349 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936664962,115 - 966,797 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BBC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,037,104 - 53,046,887 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,037,103 - 53,046,902 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2648,411,044 - 48,420,848 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Bbc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,470,475 - 6,476,754 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,467,716 - 6,476,754 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 33 20 59
Below cutoff 3 1

Sequence


RefSeq Acc Id: ENSCSAT00000001006   ⟹   ENSCSAP00000015061
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl640,561,274 - 40,567,853 (-)Ensembl
RefSeq Acc Id: XM_007997336   ⟹   XP_007995527
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1640,560,550 - 40,570,679 (-)NCBI
Vero_WHO_p1.0NW_02366607320,284,513 - 20,294,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007997337   ⟹   XP_007995528
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1640,560,550 - 40,572,428 (-)NCBI
Vero_WHO_p1.0NW_02366607320,284,513 - 20,296,281 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007995527 (Get FASTA)   NCBI Sequence Viewer  
  XP_007995528 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015061
  ENSCSAP00000015061.1
RefSeq Acc Id: XP_007995528   ⟸   XM_007997337
- UniProtKB: A0A0D9S2H2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007995527   ⟸   XM_007997336
- UniProtKB: A0A0D9S2H2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015061   ⟸   ENSCSAT00000001006


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002981 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001006.1 UniProtKB/TrEMBL
InterPro Bbc3 UniProtKB/TrEMBL
NCBI Gene BBC3 ENTREZGENE
PANTHER BCL-2-BINDING COMPONENT 3, ISOFORMS 3/4 UniProtKB/TrEMBL
  PTHR28639 UniProtKB/TrEMBL
Pfam PUMA UniProtKB/TrEMBL
UniProt A0A0D9S2H2 ENTREZGENE, UniProtKB/TrEMBL