TOX3 (TOX high mobility group box family member 3) - Rat Genome Database

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Gene: TOX3 (TOX high mobility group box family member 3) Chlorocebus sabaeus
Analyze
Symbol: TOX3
Name: TOX high mobility group box family member 3
RGD ID: 18397076
Description: ENCODES a protein that exhibits chromatin binding (inferred); chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN calcium-mediated signaling (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); genetic disease (ortholog); Liver Neoplasms (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1538,197,059 - 38,304,582 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl538,197,066 - 38,304,264 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604738,104,732 - 38,213,117 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TOX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1538,197,059 - 38,304,582 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl538,197,066 - 38,304,264 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604738,104,732 - 38,213,117 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TOX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381652,436,416 - 52,547,802 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1652,436,417 - 52,547,802 (-)EnsemblGRCh38hg38GRCh38
GRCh371652,470,328 - 52,581,714 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361651,029,418 - 51,138,307 (-)NCBINCBI36Build 36hg18NCBI36
Celera1636,987,398 - 37,097,166 (-)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1638,359,856 - 38,469,498 (-)NCBIHuRef
CHM1_11653,879,440 - 53,989,145 (-)NCBICHM1_1
T2T-CHM13v2.01658,234,308 - 58,345,684 (-)NCBIT2T-CHM13v2.0
Tox3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39890,973,665 - 91,075,746 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl890,973,668 - 91,074,971 (-)EnsemblGRCm39 Ensembl
GRCm38890,247,110 - 90,349,029 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl890,247,040 - 90,348,343 (-)EnsemblGRCm38mm10GRCm38
MGSCv37892,771,009 - 92,872,151 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36893,137,145 - 93,238,357 (-)NCBIMGSCv36mm8
Celera894,556,870 - 94,657,697 (-)NCBICelera
Cytogenetic Map8C4NCBI
cM Map843.96NCBI
Tox3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81932,820,957 - 32,929,776 (+)NCBIGRCr8
mRatBN7.21916,648,338 - 16,757,151 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1916,648,342 - 16,757,148 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1918,333,723 - 18,442,203 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01923,528,296 - 23,636,779 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01926,480,173 - 26,589,136 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01918,079,022 - 18,188,366 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1918,079,094 - 18,188,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01929,134,015 - 29,241,570 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41917,945,550 - 17,975,738 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11917,871,205 - 17,980,560 (+)NCBI
Celera1916,625,712 - 16,655,906 (+)NCBICelera
Cytogenetic Map19p11NCBI
Tox3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543310,327,342 - 10,426,540 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543310,328,886 - 10,426,540 (-)NCBIChiLan1.0ChiLan1.0
TOX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21861,882,934 - 61,995,345 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11667,802,062 - 67,912,776 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01632,690,290 - 32,800,974 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11651,570,692 - 51,679,332 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1651,570,692 - 51,679,332 (-)Ensemblpanpan1.1panPan2
TOX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1262,981,706 - 63,087,519 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl262,981,611 - 63,086,684 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha259,551,572 - 59,657,647 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0263,524,396 - 63,630,965 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl263,525,270 - 63,630,127 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1260,347,846 - 60,453,909 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0261,368,939 - 61,475,720 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0262,252,600 - 62,358,859 (+)NCBIUU_Cfam_GSD_1.0
Tox3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934954,200,946 - 54,305,460 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364755,283,622 - 5,388,067 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364755,283,615 - 5,388,104 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl632,494,236 - 32,609,926 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1632,492,686 - 32,609,923 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2629,293,934 - 29,420,230 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tox3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247574,168,672 - 4,276,392 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247574,144,799 - 4,275,154 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 20
Low 14 11 40
Below cutoff 2 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000003348   ⟹   ENSCSAP00000001630
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl538,197,066 - 38,304,264 (-)Ensembl
RefSeq Acc Id: XM_007993127   ⟹   XP_007991318
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1538,197,059 - 38,304,582 (-)NCBI
Vero_WHO_p1.0NW_02366604738,104,732 - 38,213,117 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007993133   ⟹   XP_007991324
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1538,197,059 - 38,304,582 (-)NCBI
Vero_WHO_p1.0NW_02366604738,104,918 - 38,213,117 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007991318 (Get FASTA)   NCBI Sequence Viewer  
  XP_007991324 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001630
  ENSCSAP00000001630.1
Reference Protein Sequences
RefSeq Acc Id: XP_007991324   ⟸   XM_007993133
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007991318   ⟸   XM_007993127
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QZ41 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000001630   ⟸   ENSCSAT00000003348


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005317 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003348.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103232814 UniProtKB/TrEMBL
NCBI Gene TOX3 ENTREZGENE
PANTHER AGAP000281-PA UniProtKB/TrEMBL
  TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3 UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
PRINTS HIGHMOBLTY12 UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
UniProt A0A0D9QZ41 ENTREZGENE, UniProtKB/TrEMBL