FANCI (FA complementation group I) - Rat Genome Database

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Gene: FANCI (FA complementation group I) Chlorocebus sabaeus
Analyze
Symbol: FANCI
Name: FA complementation group I
RGD ID: 18548342
Description: ENCODES a protein that exhibits DNA polymerase binding (inferred); INVOLVED IN positive regulation of protein ubiquitination (ortholog); ASSOCIATED WITH Alpers-Huttenlocher syndrome (ortholog); autosomal dominant progressive external ophthalmoplegia 1 (ortholog); autosomal recessive progressive external ophthalmoplegia 1 (ortholog); FOUND IN DNA repair complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Fanconi anemia complementation group I; Fanconi anemia group I protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1297,788,983 - 7,864,505 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl297,790,458 - 7,855,552 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605938,950,782 - 39,037,352 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
DNA repair complex  (IEA,ISO)
nucleoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FANCI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1297,788,983 - 7,864,505 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl297,790,458 - 7,855,552 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605938,950,782 - 39,037,352 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FANCI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,243,979 - 89,317,259 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,243,945 - 89,317,261 (+)EnsemblGRCh38hg38GRCh38
GRCh371589,787,210 - 89,860,490 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361587,588,198 - 87,661,366 (+)NCBINCBI36Build 36hg18NCBI36
Celera1566,188,469 - 66,261,721 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1565,899,078 - 65,972,245 (+)NCBIHuRef
CHM1_11589,628,176 - 89,701,402 (+)NCBICHM1_1
T2T-CHM13v2.01586,998,773 - 87,072,086 (+)NCBIT2T-CHM13v2.0
Fanci
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,042,056 - 79,100,013 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,041,677 - 79,100,012 (+)EnsemblGRCm39 Ensembl
GRCm38779,392,312 - 79,450,266 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,391,929 - 79,450,264 (+)EnsemblGRCm38mm10GRCm38
MGSCv37786,537,224 - 86,595,150 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,265,866 - 79,323,777 (+)NCBIMGSCv36mm8
Celera776,790,497 - 76,852,630 (+)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.01NCBI
Fanci
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,736,636 - 142,792,999 (+)NCBIGRCr8
mRatBN7.21133,327,264 - 133,383,661 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,327,297 - 133,383,640 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01141,116,565 - 141,172,997 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,120,166 - 141,172,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01142,078,658 - 142,134,772 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,144,029 - 135,196,828 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1125,390,494 - 125,446,830 (+)NCBICelera
Cytogenetic Map1q31NCBI
Fanci
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,788,922 - 15,853,480 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,788,812 - 15,857,933 (-)NCBIChiLan1.0ChiLan1.0
FANCI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21678,791,536 - 78,864,917 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11582,496,027 - 82,569,303 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01567,935,882 - 68,009,033 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11587,142,871 - 87,215,271 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1587,142,871 - 87,215,271 (+)Ensemblpanpan1.1panPan2
FANCI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,282,955 - 52,357,874 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,282,731 - 52,357,226 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,917,864 - 54,992,648 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0352,700,699 - 52,774,876 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl352,700,713 - 52,774,871 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,223,438 - 52,297,602 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,433,730 - 52,507,862 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0352,772,736 - 52,847,574 (+)NCBIUU_Cfam_GSD_1.0
Fanci
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640131,154,626 - 131,236,280 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648315,106,902 - 15,179,094 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648315,096,215 - 15,179,856 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FANCI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl754,811,027 - 54,889,998 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1754,811,024 - 54,889,992 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2759,782,093 - 59,865,530 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Fanci
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476816,427,060 - 16,493,850 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 20 60
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015264   ⟹   ENSCSAP00000013208
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl297,790,458 - 7,855,552 (+)Ensembl
RefSeq Acc Id: XM_007990349   ⟹   XP_007988540
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1297,788,991 - 7,864,505 (+)NCBI
Vero_WHO_p1.0NW_02366605938,950,782 - 39,037,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007990350   ⟹   XP_007988541
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1297,788,991 - 7,864,505 (+)NCBI
Vero_WHO_p1.0NW_02366605938,951,256 - 39,037,317 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037987701   ⟹   XP_037843629
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605938,950,782 - 39,006,106 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007988540 (Get FASTA)   NCBI Sequence Viewer  
  XP_007988541 (Get FASTA)   NCBI Sequence Viewer  
  XP_037843629 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013208.1
Reference Protein Sequences
RefSeq Acc Id: XP_007988541   ⟸   XM_007990350
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RX69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007988540   ⟸   XM_007990349
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RX69 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013208   ⟸   ENSCSAT00000015264
RefSeq Acc Id: XP_037843629   ⟸   XM_037987701
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017169 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015264.1 UniProtKB/TrEMBL
InterPro FANCI UniProtKB/TrEMBL
  FANCI_HD1 UniProtKB/TrEMBL
  FANCI_HD2 UniProtKB/TrEMBL
  FANCI_S1 UniProtKB/TrEMBL
  FANCI_S1-cap UniProtKB/TrEMBL
  FANCI_S2 UniProtKB/TrEMBL
  FANCI_S3 UniProtKB/TrEMBL
  FANCI_S4 UniProtKB/TrEMBL
NCBI Gene FANCI ENTREZGENE
PANTHER FANCONI ANEMIA GROUP I PROTEIN UniProtKB/TrEMBL
  PTHR21818 UniProtKB/TrEMBL
Pfam FANCI_HD1 UniProtKB/TrEMBL
  FANCI_HD2 UniProtKB/TrEMBL
  FANCI_S1 UniProtKB/TrEMBL
  FANCI_S1-cap UniProtKB/TrEMBL
  FANCI_S2 UniProtKB/TrEMBL
  FANCI_S3 UniProtKB/TrEMBL
  FANCI_S4 UniProtKB/TrEMBL
UniProt A0A0D9RX69 ENTREZGENE, UniProtKB/TrEMBL