CDC27 (cell division cycle 27) - Rat Genome Database

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Gene: CDC27 (cell division cycle 27) Chlorocebus sabaeus
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Symbol: CDC27
Name: cell division cycle 27
RGD ID: 18348101
Description: ENCODES a protein that exhibits protein phosphatase binding (inferred); INVOLVED IN metaphase/anaphase transition of mitotic cell cycle (ortholog); ASSOCIATED WITH esophageal atresia (ortholog); hepatocellular carcinoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN anaphase-promoting complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cell division cycle protein 27 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11659,497,731 - 59,564,298 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1659,497,713 - 59,564,480 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607730,209,741 - 30,276,471 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDC27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11659,497,731 - 59,564,298 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1659,497,713 - 59,564,480 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607730,209,741 - 30,276,471 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CDC27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,117,703 - 47,189,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1747,117,703 - 47,189,422 (-)EnsemblGRCh38hg38GRCh38
GRCh371745,195,069 - 45,266,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361742,552,625 - 42,621,664 (-)NCBINCBI36Build 36hg18NCBI36
Build 341742,552,624 - 42,621,664NCBI
Celera1741,645,340 - 41,716,724 (-)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1740,572,496 - 40,644,750 (-)NCBIHuRef
CHM1_11745,260,254 - 45,331,607 (-)NCBICHM1_1
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBIT2T-CHM13v2.0
Cdc27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911104,393,350 - 104,441,371 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11104,393,571 - 104,441,446 (-)EnsemblGRCm39 Ensembl
GRCm3811104,502,524 - 104,550,620 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11104,502,745 - 104,550,620 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711104,363,838 - 104,411,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611104,318,606 - 104,376,937 (-)NCBIMGSCv36mm8
Celera11116,230,588 - 116,278,484 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1167.79NCBI
Cdc27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81089,900,676 - 89,949,770 (-)NCBIGRCr8
mRatBN7.21089,400,720 - 89,449,816 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1089,400,940 - 89,449,736 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1094,440,366 - 94,485,331 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01093,903,884 - 93,948,519 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01089,306,665 - 89,353,815 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01092,551,754 - 92,602,214 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1092,554,081 - 92,602,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01092,314,321 - 92,364,553 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41093,678,790 - 93,725,987 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11093,693,161 - 93,740,357 (-)NCBI
Celera1088,097,228 - 88,143,638 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Cdc27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554789,927,871 - 10,002,020 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554789,927,871 - 10,002,020 (+)NCBIChiLan1.0ChiLan1.0
CDC27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,825,006 - 17,896,577 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,790,590 - 19,860,083 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01710,259,194 - 10,331,011 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11710,473,516 - 10,545,549 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1710,473,646 - 10,545,549 (+)Ensemblpanpan1.1panPan2
CDC27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.199,281,152 - 9,351,629 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl99,281,196 - 9,348,678 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha910,946,699 - 11,017,232 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0910,870,030 - 10,940,621 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl910,870,065 - 10,940,617 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.199,884,169 - 9,954,826 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0917,569,886 - 17,640,242 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0917,516,367 - 17,586,916 (-)NCBIUU_Cfam_GSD_1.0
Cdc27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560216,432,450 - 16,493,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365412,700,997 - 2,762,147 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365412,700,997 - 2,762,180 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,810,910 - 16,882,269 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,810,868 - 16,882,271 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21216,834,050 - 16,905,448 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cdc27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248492,026,425 - 2,092,857 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248492,026,433 - 2,105,626 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 10 60
Low 10
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000001837   ⟹   ENSCSAP00000000175
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1659,497,713 - 59,564,480 (+)Ensembl
RefSeq Acc Id: XM_008012275   ⟹   XP_008010466
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11659,497,731 - 59,564,298 (+)NCBI
Vero_WHO_p1.0NW_02366607730,209,741 - 30,276,471 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012276   ⟹   XP_008010467
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11659,497,758 - 59,564,298 (+)NCBI
Vero_WHO_p1.0NW_02366607730,209,741 - 30,273,996 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012277   ⟹   XP_008010468
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11659,497,731 - 59,564,298 (+)NCBI
Vero_WHO_p1.0NW_02366607730,209,753 - 30,276,471 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012278   ⟹   XP_008010469
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11659,497,758 - 59,564,298 (+)NCBI
Vero_WHO_p1.0NW_02366607730,209,753 - 30,276,471 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012280   ⟹   XP_008010471
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11659,497,776 - 59,564,298 (+)NCBI
Vero_WHO_p1.0NW_02366607730,209,764 - 30,273,996 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012281   ⟹   XP_008010472
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11659,497,775 - 59,564,298 (+)NCBI
Vero_WHO_p1.0NW_02366607730,209,753 - 30,276,471 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037993371   ⟹   XP_037849299
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607730,209,741 - 30,271,959 (+)NCBI
RefSeq Acc Id: XM_037993372   ⟹   XP_037849300
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607730,209,741 - 30,271,959 (+)NCBI
RefSeq Acc Id: XP_008010466   ⟸   XM_008012275
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008010468   ⟸   XM_008012277
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008010467   ⟸   XM_008012276
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008010469   ⟸   XM_008012278
- Peptide Label: isoform X4
RefSeq Acc Id: XP_008010472   ⟸   XM_008012281
- Peptide Label: isoform X6
RefSeq Acc Id: XP_008010471   ⟸   XM_008012280
- Peptide Label: isoform X5
RefSeq Acc Id: ENSCSAP00000000175   ⟸   ENSCSAT00000001837
RefSeq Acc Id: XP_037849299   ⟸   XM_037993371
- Peptide Label: isoform X7
RefSeq Acc Id: XP_037849300   ⟸   XM_037993372
- Peptide Label: isoform X8


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001837.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_1 UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene CDC27 ENTREZGENE
PANTHER CELL DIVISION CYCLE 16,23,27 UniProtKB/TrEMBL
  CELL DIVISION CYCLE PROTEIN 27 HOMOLOG UniProtKB/TrEMBL
Pfam ANAPC3 UniProtKB/TrEMBL
  TPR_1 UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
  TPR_REGION UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A0D9QUY6_CHLSB UniProtKB/TrEMBL