USP2 (ubiquitin specific peptidase 2) - Rat Genome Database

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Gene: USP2 (ubiquitin specific peptidase 2) Chlorocebus sabaeus
Analyze
Symbol: USP2
Name: ubiquitin specific peptidase 2
RGD ID: 18788386
Description: ENCODES a protein that exhibits cyclin binding (inferred); cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN negative regulation of calcium ion transport (ortholog); negative regulation of skeletal muscle tissue development (ortholog); positive regulation of skeletal muscle tissue development (ortholog); ASSOCIATED WITH CD3epsilon deficiency (ortholog); chromosome 11 partial duplication syndrome (ortholog); Dwarfism (ortholog); FOUND IN centrosome (ortholog); membrane (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,733,097 - 110,760,119 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,734,737 - 110,742,186 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,273,873 - 15,301,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
USP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,733,097 - 110,760,119 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,734,737 - 110,742,186 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,273,873 - 15,301,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
USP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,355,215 - 119,381,690 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,355,215 - 119,381,711 (-)EnsemblGRCh38hg38GRCh38
GRCh3711119,225,925 - 119,252,400 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,732,163 - 118,757,575 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411118,732,754 - 118,740,102NCBI
Celera11116,386,596 - 116,413,112 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11115,167,582 - 115,194,094 (-)NCBIHuRef
CHM1_111119,112,501 - 119,139,031 (-)NCBICHM1_1
T2T-CHM13v2.011119,376,744 - 119,403,221 (-)NCBIT2T-CHM13v2.0
Usp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39943,978,318 - 44,006,924 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl943,978,318 - 44,006,924 (+)EnsemblGRCm39 Ensembl
GRCm38944,067,021 - 44,095,627 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,067,021 - 44,095,627 (+)EnsemblGRCm38mm10GRCm38
MGSCv37943,875,104 - 43,903,710 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36943,818,162 - 43,845,472 (+)NCBIMGSCv36mm8
Celera941,325,008 - 41,353,422 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map924.53NCBI
Usp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,308,264 - 53,336,800 (+)NCBIGRCr8
mRatBN7.2844,411,457 - 44,439,668 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,411,607 - 44,438,331 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx849,912,278 - 49,936,574 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,190,992 - 48,215,284 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,058,574 - 46,082,906 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,403,985 - 48,432,525 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,406,260 - 48,430,885 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,020,039 - 47,048,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,052,085 - 47,076,321 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,060,850 - 47,085,070 (+)NCBI
Celera844,001,154 - 44,025,278 (+)NCBICelera
Cytogenetic Map8q22NCBI
Usp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,433,302 - 20,457,493 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,435,778 - 20,461,898 (-)NCBIChiLan1.0ChiLan1.0
USP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29120,063,452 - 120,090,139 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111121,166,911 - 121,193,613 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011114,196,725 - 114,223,411 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111118,124,350 - 118,150,868 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11118,124,350 - 118,150,868 (-)Ensemblpanpan1.1panPan2
USP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,525,685 - 14,550,914 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,525,797 - 14,549,291 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,579,281 - 14,604,451 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,469,193 - 14,494,315 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,469,306 - 14,494,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,607,448 - 14,632,620 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,511,479 - 14,536,582 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,551,610 - 14,576,719 (+)NCBIUU_Cfam_GSD_1.0
Usp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,362,834 - 101,388,611 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,285,819 - 4,307,925 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365424,284,243 - 4,310,545 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,563,482 - 46,590,392 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,563,469 - 46,590,392 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,595,416 - 51,622,353 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Usp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,729,770 - 14,754,991 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,729,762 - 14,755,982 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in USP2
429 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 19 35 35 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000000508   ⟹   ENSCSAP00000015554
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1110,734,737 - 110,742,186 (-)Ensembl
RefSeq Acc Id: XM_008021202   ⟹   XP_008019393
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,733,097 - 110,760,119 (-)NCBI
Vero_WHO_p1.0NW_02366604315,273,873 - 15,301,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021203   ⟹   XP_008019394
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,733,097 - 110,754,764 (-)NCBI
Vero_WHO_p1.0NW_02366604315,280,157 - 15,301,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021204   ⟹   XP_008019395
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,733,097 - 110,757,728 (-)NCBI
Vero_WHO_p1.0NW_02366604315,277,205 - 15,301,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021205   ⟹   XP_008019396
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,733,097 - 110,742,235 (-)NCBI
Vero_WHO_p1.0NW_02366604315,292,342 - 15,301,399 (+)NCBI
Sequence:
RefSeq Acc Id: XR_503381
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,733,097 - 110,760,053 (-)NCBI
Vero_WHO_p1.0NW_02366604315,273,873 - 15,301,399 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008019393 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019394 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019395 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019396 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015554
  ENSCSAP00000015554.1
RefSeq Acc Id: XP_008019393   ⟸   XM_008021202
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008019395   ⟸   XM_008021204
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008019394   ⟸   XM_008021203
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008019396   ⟸   XM_008021205
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S3W5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000015554   ⟸   ENSCSAT00000000508


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002490 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000508.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
NCBI Gene USP2 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A0D9S3W5 ENTREZGENE, UniProtKB/TrEMBL