SOAT1 (sterol O-acyltransferase 1) - Rat Genome Database

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Gene: SOAT1 (sterol O-acyltransferase 1) Chlorocebus sabaeus
Analyze
Symbol: SOAT1
Name: sterol O-acyltransferase 1
RGD ID: 18463297
Description: ENCODES a protein that exhibits identical protein binding (ortholog); sterol O-acyltransferase activity (ortholog); INVOLVED IN cholesterol metabolic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); aortic atherosclerosis (ortholog); atherosclerosis (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12549,998,197 - 50,061,433 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2550,001,910 - 50,061,173 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605551,485,709 - 51,549,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SOAT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12549,998,197 - 50,061,433 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2550,001,910 - 50,061,173 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605551,485,709 - 51,549,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SOAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381179,293,797 - 179,358,680 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1179,293,714 - 179,358,680 (+)EnsemblGRCh38hg38GRCh38
GRCh371179,262,932 - 179,327,815 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361177,529,640 - 177,591,076 (+)NCBINCBI36Build 36hg18NCBI36
Build 341175,994,673 - 176,056,109NCBI
Celera1152,371,279 - 152,432,730 (+)NCBICelera
Cytogenetic Map1q25.2NCBI
HuRef1150,490,026 - 150,555,022 (+)NCBIHuRef
CHM1_11180,686,373 - 180,751,320 (+)NCBICHM1_1
T2T-CHM13v2.01178,648,799 - 178,713,729 (+)NCBIT2T-CHM13v2.0
Soat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391156,255,678 - 156,301,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1156,252,095 - 156,301,901 (-)EnsemblGRCm39 Ensembl
GRCm381156,428,108 - 156,474,328 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1156,424,525 - 156,474,331 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,358,239 - 158,404,459 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,265,149 - 158,310,920 (-)NCBIMGSCv36mm8
Celera1158,822,751 - 158,868,673 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map167.71NCBI
Soat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81371,105,178 - 71,147,776 (-)NCBIGRCr8
mRatBN7.21368,552,274 - 68,597,529 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1368,552,317 - 68,597,494 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1371,134,597 - 71,176,925 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01372,454,344 - 72,496,807 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01369,715,839 - 69,758,305 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01374,035,258 - 74,077,759 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1374,035,080 - 74,077,783 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01378,956,528 - 78,999,029 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41371,420,862 - 71,463,365 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11371,435,049 - 71,477,553 (-)NCBI
Celera1368,416,482 - 68,458,206 (-)NCBICelera
Cytogenetic Map13q22NCBI
Soat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540618,655,894 - 18,706,891 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540618,644,351 - 18,708,666 (+)NCBIChiLan1.0ChiLan1.0
SOAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2170,405,471 - 70,466,287 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1170,065,689 - 70,130,644 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01154,776,305 - 154,840,594 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11158,464,886 - 158,529,952 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1158,464,886 - 158,524,909 (+)Ensemblpanpan1.1panPan2
SOAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1720,481,386 - 20,556,706 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl720,486,069 - 20,546,055 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha720,005,887 - 20,081,197 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0720,217,662 - 20,292,968 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl720,220,698 - 20,293,045 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1720,126,140 - 20,201,100 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0720,232,924 - 20,307,851 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0720,368,010 - 20,443,005 (-)NCBIUU_Cfam_GSD_1.0
Soat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934491,767,856 - 91,822,797 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364819,616,850 - 9,669,705 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364819,614,605 - 9,669,705 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9121,045,234 - 121,113,692 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19121,045,211 - 121,112,393 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29132,895,468 - 132,952,031 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Soat1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247712,994,696 - 3,055,916 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247712,992,752 - 3,055,842 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 6 32
Low 14 28
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000010193   ⟹   ENSCSAP00000008289
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2550,001,910 - 50,061,173 (-)Ensembl
RefSeq Acc Id: XM_007989335   ⟹   XP_007987526
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12549,998,197 - 50,061,419 (-)NCBI
Vero_WHO_p1.0NW_02366605551,485,709 - 51,549,654 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007989336   ⟹   XP_007987527
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12549,998,855 - 50,061,433 (-)NCBI
Vero_WHO_p1.0NW_02366605551,486,024 - 51,549,549 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007987526 (Get FASTA)   NCBI Sequence Viewer  
  XP_007987527 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008289
  ENSCSAP00000008289.1
Reference Protein Sequences
RefSeq Acc Id: XP_007987526   ⟸   XM_007989335
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RI50 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007987527   ⟸   XM_007989336
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RI50 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000008289   ⟸   ENSCSAT00000010193


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012108 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010193.1 UniProtKB/TrEMBL
InterPro MBOAT_fam UniProtKB/TrEMBL
  Oat_ACAT_DAG_ARE UniProtKB/TrEMBL
  Sterol_acyltranf_meta UniProtKB/TrEMBL
NCBI Gene SOAT1 ENTREZGENE
PANTHER PTHR10408 UniProtKB/TrEMBL
  STEROL O-ACYLTRANSFERASE 1 UniProtKB/TrEMBL
Pfam MBOAT UniProtKB/TrEMBL
PIRSF Oat_ACAT_DAG_ARE UniProtKB/TrEMBL
  Sterol_acyltranf_ACAT UniProtKB/TrEMBL
UniProt A0A0D9RI50 ENTREZGENE, UniProtKB/TrEMBL