SCD (stearoyl-CoA desaturase) - Rat Genome Database

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Gene: SCD (stearoyl-CoA desaturase) Chlorocebus sabaeus
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Symbol: SCD
Name: stearoyl-CoA desaturase
RGD ID: 18511524
Description: ENCODES a protein that exhibits iron ion binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN lipid biosynthetic process (ortholog); monounsaturated fatty acid biosynthetic process (ortholog); response to nutrient (ortholog); PARTICIPATES IN fatty acid metabolic pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); atherosclerosis (ortholog); carcinoma (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-CoA desaturase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1993,380,812 - 93,398,860 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl993,380,914 - 93,398,912 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604854,387,804 - 54,405,855 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SCD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1993,380,812 - 93,398,860 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl993,380,914 - 93,398,912 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604854,387,804 - 54,405,855 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SCD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810100,347,233 - 100,364,826 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10100,347,233 - 100,364,826 (+)EnsemblGRCh38hg38GRCh38
GRCh3710102,106,990 - 102,124,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610102,096,762 - 102,114,578 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410102,096,761 - 102,114,577NCBI
Celera1095,844,653 - 95,862,464 (+)NCBICelera
Cytogenetic Map10q24.31NCBI
HuRef1095,735,654 - 95,753,465 (+)NCBIHuRef
CHM1_110102,391,212 - 102,409,039 (+)NCBICHM1_1
T2T-CHM13v2.010101,231,456 - 101,249,056 (+)NCBIT2T-CHM13v2.0
Scd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391944,282,115 - 44,295,303 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1944,282,113 - 44,295,303 (+)EnsemblGRCm39 Ensembl
GRCm381944,293,676 - 44,306,864 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1944,293,674 - 44,306,864 (+)EnsemblGRCm38mm10GRCm38
MGSCv371944,368,166 - 44,381,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361944,347,399 - 44,360,171 (+)NCBIMGSCv36mm8
Celera1945,067,400 - 45,080,568 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1937.98NCBI
Scd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81253,218,968 - 253,232,101 (-)NCBIGRCr8
mRatBN7.21243,269,745 - 243,282,878 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,269,747 - 243,282,562 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1251,420,000 - 251,432,600 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01258,116,587 - 258,129,187 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01250,770,154 - 250,782,754 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01264,159,966 - 264,173,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1264,160,129 - 264,172,729 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01271,602,885 - 271,615,985 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,458,860 - 249,471,460 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11249,717,543 - 249,730,359 (-)NCBI
Celera1239,084,889 - 239,097,489 (-)NCBICelera
Cytogenetic Map1q54NCBI
SCD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28112,231,203 - 112,249,176 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110112,236,522 - 112,254,495 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01096,948,212 - 96,965,633 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110100,428,627 - 100,446,647 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10100,429,615 - 100,442,776 (+)Ensemblpanpan1.1panPan2
SCD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12813,112,741 - 13,129,129 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2813,113,006 - 13,125,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2813,283,628 - 13,300,028 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02813,581,765 - 13,598,163 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2813,581,805 - 13,598,155 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12813,128,503 - 13,144,867 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02813,166,524 - 13,182,907 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02813,300,894 - 13,317,236 (+)NCBIUU_Cfam_GSD_1.0
SCD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14111,461,569 - 111,478,020 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114111,461,560 - 111,478,033 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214120,964,681 - 120,980,911 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q27NCBI


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000003647   ⟹   ENSCSAP00000001922
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl993,380,914 - 93,398,912 (+)Ensembl
RefSeq Acc Id: XM_007963839   ⟹   XP_007962030
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1993,380,812 - 93,398,860 (+)NCBI
Vero_WHO_p1.0NW_02366604854,387,804 - 54,405,855 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038009452   ⟹   XP_037865380
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604854,387,866 - 54,405,855 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007962030 (Get FASTA)   NCBI Sequence Viewer  
  XP_037865380 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001922.1
RefSeq Acc Id: XP_007962030   ⟸   XM_007963839
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QZY3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001922   ⟸   ENSCSAT00000003647
RefSeq Acc Id: XP_037865380   ⟸   XM_038009452
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QZY3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005611 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003647.1 UniProtKB/TrEMBL
InterPro Acyl-CoA_DS UniProtKB/TrEMBL
  FADS-1_CS UniProtKB/TrEMBL
KEGG Report csab:103216387 UniProtKB/TrEMBL
NCBI Gene SCD ENTREZGENE
PANTHER PTHR11351 UniProtKB/TrEMBL
  STEAROYL-COA DESATURASE UniProtKB/TrEMBL
PRINTS FACDDSATRASE UniProtKB/TrEMBL
PROSITE FATTY_ACID_DESATUR_1 UniProtKB/TrEMBL
UniProt A0A0D9QZY3 ENTREZGENE, UniProtKB/TrEMBL