NYNRIN (NYN domain and retroviral integrase containing) - Rat Genome Database

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Gene: NYNRIN (NYN domain and retroviral integrase containing) Chlorocebus sabaeus
Analyze
Symbol: NYNRIN
Name: NYN domain and retroviral integrase containing
RGD ID: 18662907
Description: ENCODES a protein that exhibits mRNA binding (inferred); nucleic acid binding (inferred); RNA endonuclease activity (inferred); INVOLVED IN DNA integration (inferred); DNA synthesis involved in DNA repair (inferred); DNA-templated DNA replication (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); hepatoblastoma (ortholog); lysinuric protein intolerance (ortholog); FOUND IN cytoplasmic ribonucleoprotein granule (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein NYNRIN
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,380,864 - 1,401,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,381,483 - 1,401,750 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603613,067,287 - 13,087,957 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NYNRIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,380,864 - 1,401,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,381,483 - 1,401,750 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603613,067,287 - 13,087,957 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NYNRIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,399,003 - 24,419,283 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,399,003 - 24,419,283 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,868,209 - 24,888,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,937,832 - 23,958,334 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,946,953 - 23,958,328NCBI
Celera144,732,635 - 4,753,130 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,982,163 - 5,003,157 (+)NCBIHuRef
CHM1_11424,866,568 - 24,887,067 (+)NCBICHM1_1
T2T-CHM13v2.01418,597,752 - 18,618,021 (+)NCBIT2T-CHM13v2.0
Nynrin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391456,091,572 - 56,112,193 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1456,091,467 - 56,112,193 (+)EnsemblGRCm39 Ensembl
GRCm381455,854,115 - 55,874,736 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,854,010 - 55,874,736 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,472,952 - 56,493,573 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,808,087 - 54,828,812 (+)NCBIMGSCv36mm8
Celera1453,656,002 - 53,676,413 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Nynrin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,302,778 - 33,325,120 (+)NCBIGRCr8
mRatBN7.21529,332,873 - 29,355,215 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,332,869 - 29,355,215 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01534,520,040 - 34,541,671 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,520,142 - 34,539,930 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,408,544 - 38,429,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1528,907,311 - 28,928,945 (+)NCBICelera
Cytogenetic Map15p13NCBI
Nynrin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540935,889,773 - 35,910,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540935,890,158 - 35,910,859 (-)NCBIChiLan1.0ChiLan1.0
NYNRIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,753,394 - 25,774,318 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,969,975 - 24,991,457 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,174,889 - 5,195,706 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,298,139 - 23,318,905 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,298,139 - 23,318,905 (+)Ensemblpanpan1.1panPan2
NYNRIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,368,702 - 4,389,565 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,368,560 - 4,387,842 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,290,642 - 4,311,331 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,480,427 - 4,501,112 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,480,470 - 4,501,112 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.184,169,884 - 4,190,658 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,232,603 - 4,253,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,494,843 - 4,515,537 (+)NCBIUU_Cfam_GSD_1.0
Nynrin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,233,896 - 36,254,730 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722134,190 - 155,115 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722134,221 - 155,020 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NYNRIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl774,879,260 - 74,898,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1774,877,910 - 74,898,596 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,148,821 - 80,169,569 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Nynrin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,094,908 - 8,118,679 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,093,119 - 8,114,465 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 20
Low 16 13 40
Below cutoff 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000013950   ⟹   ENSCSAP00000011933
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl241,381,483 - 1,401,750 (+)Ensembl
RefSeq Acc Id: XM_007986342   ⟹   XP_007984533
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1241,380,864 - 1,401,710 (+)NCBI
Vero_WHO_p1.0NW_02366603613,067,287 - 13,087,957 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037985643   ⟹   XP_037841571
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603613,067,399 - 13,087,957 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007984533 (Get FASTA)   NCBI Sequence Viewer  
  XP_037841571 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011933
  ENSCSAP00000011933.1
Reference Protein Sequences
RefSeq Acc Id: XP_007984533   ⟸   XM_007986342
- UniProtKB: A0A0D9RTJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000011933   ⟸   ENSCSAT00000013950
RefSeq Acc Id: XP_037841571   ⟸   XM_037985643
- UniProtKB: A0A0D9RTJ4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015855 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013950.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.340.70 UniProtKB/TrEMBL
  3.10.20.370 UniProtKB/TrEMBL
  3.30.420.10 UniProtKB/TrEMBL
  3.30.70.270 UniProtKB/TrEMBL
  3.40.50.11980 UniProtKB/TrEMBL
InterPro DNA/RNA_pol_sf UniProtKB/TrEMBL
  Integrase_cat-core UniProtKB/TrEMBL
  Integrase_H2C2 UniProtKB/TrEMBL
  Rev_trsase/Diguanyl_cyclase UniProtKB/TrEMBL
  RNase_Zc3h12_NYN UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_domain UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
  RT_RNaseH_2 UniProtKB/TrEMBL
KEGG Report csab:103228736 UniProtKB/TrEMBL
NCBI Gene NYNRIN ENTREZGENE
PANTHER N4BP1-RELATED UniProtKB/TrEMBL
  PROTEIN NYNRIN UniProtKB/TrEMBL
Pfam Integrase_H2C2 UniProtKB/TrEMBL
  RNase_Zc3h12a UniProtKB/TrEMBL
  RT_RNaseH_2 UniProtKB/TrEMBL
PROSITE INTEGRASE UniProtKB/TrEMBL
  RNASE_H_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF53098 UniProtKB/TrEMBL
  SSF56672 UniProtKB/TrEMBL
UniProt A0A0D9RTJ4 ENTREZGENE, UniProtKB/TrEMBL