NYNRIN (NYN domain and retroviral integrase containing) - Rat Genome Database

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Gene: NYNRIN (NYN domain and retroviral integrase containing) Sus scrofa
Analyze
Symbol: NYNRIN
Name: NYN domain and retroviral integrase containing
RGD ID: 14026531
Description: ENCODES a protein that exhibits nucleic acid binding (inferred); RNA-DNA hybrid ribonuclease activity (inferred); INVOLVED IN DNA integration (inferred); DNA metabolic process (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); hepatoblastoma (ortholog); lysinuric protein intolerance (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl774,879,260 - 74,898,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1774,877,910 - 74,898,596 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,148,821 - 80,169,569 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NYNRIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl774,879,260 - 74,898,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1774,877,910 - 74,898,596 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,148,821 - 80,169,569 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NYNRIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,399,003 - 24,419,283 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,399,003 - 24,419,283 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,868,209 - 24,888,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,937,832 - 23,958,334 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,946,953 - 23,958,328NCBI
Celera144,732,635 - 4,753,130 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,982,163 - 5,003,157 (+)NCBIHuRef
CHM1_11424,866,568 - 24,887,067 (+)NCBICHM1_1
T2T-CHM13v2.01418,597,752 - 18,618,021 (+)NCBIT2T-CHM13v2.0
Nynrin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391456,091,572 - 56,112,193 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1456,091,467 - 56,112,193 (+)EnsemblGRCm39 Ensembl
GRCm381455,854,115 - 55,874,736 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,854,010 - 55,874,736 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,472,952 - 56,493,573 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,808,087 - 54,828,812 (+)NCBIMGSCv36mm8
Celera1453,656,002 - 53,676,413 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Nynrin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,302,778 - 33,325,120 (+)NCBIGRCr8
mRatBN7.21529,332,873 - 29,355,215 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,332,869 - 29,355,215 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01534,520,040 - 34,541,671 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,520,142 - 34,539,930 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,408,544 - 38,429,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1528,907,311 - 28,928,945 (+)NCBICelera
Cytogenetic Map15p13NCBI
Nynrin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540935,889,773 - 35,910,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540935,890,158 - 35,910,859 (-)NCBIChiLan1.0ChiLan1.0
NYNRIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,753,394 - 25,774,318 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,969,975 - 24,991,457 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,174,889 - 5,195,706 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,298,139 - 23,318,905 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,298,139 - 23,318,905 (+)Ensemblpanpan1.1panPan2
NYNRIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,368,702 - 4,389,565 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,368,560 - 4,387,842 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,290,642 - 4,311,331 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,480,427 - 4,501,112 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,480,470 - 4,501,112 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.184,169,884 - 4,190,658 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,232,603 - 4,253,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,494,843 - 4,515,537 (+)NCBIUU_Cfam_GSD_1.0
Nynrin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,233,896 - 36,254,730 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722134,190 - 155,115 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722134,221 - 155,020 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NYNRIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,380,864 - 1,401,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,381,483 - 1,401,750 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603613,067,287 - 13,087,957 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nynrin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,094,908 - 8,118,679 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,093,119 - 8,114,465 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NYNRIN
366 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000051953   ⟹   ENSSSCP00000053168
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl774,879,260 - 74,898,382 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000079132   ⟹   ENSSSCP00000072630
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl774,879,726 - 74,898,568 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000084763   ⟹   ENSSSCP00000063120
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl774,879,726 - 74,898,568 (-)Ensembl
RefSeq Acc Id: XM_005666233   ⟹   XP_005666290
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1774,877,910 - 74,898,596 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005666290 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000053168.1
  ENSSSCP00000063120
  ENSSSCP00000063120.1
  ENSSSCP00000072630.1
  ENSSSCP00015031379.1
  ENSSSCP00015031422.1
RefSeq Acc Id: XP_005666290   ⟸   XM_005666233
- UniProtKB: A0A5G2QEL3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000053168   ⟸   ENSSSCT00000051953
Ensembl Acc Id: ENSSSCP00000063120   ⟸   ENSSSCT00000084763
Ensembl Acc Id: ENSSSCP00000072630   ⟸   ENSSSCT00000079132
Protein Domains
Integrase catalytic   RNase H type-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032473 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015058390 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000051953.3 UniProtKB/TrEMBL
  ENSSSCT00000079132.2 UniProtKB/TrEMBL
  ENSSSCT00000084763 ENTREZGENE
  ENSSSCT00000084763.2 UniProtKB/TrEMBL
  ENSSSCT00015077875.1 UniProtKB/TrEMBL
  ENSSSCT00015077950.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.340.70 UniProtKB/TrEMBL
  3.10.20.370 UniProtKB/TrEMBL
  3.30.420.10 UniProtKB/TrEMBL
  3.30.70.270 UniProtKB/TrEMBL
  3.40.50.11980 UniProtKB/TrEMBL
InterPro DNA/RNA_pol_sf UniProtKB/TrEMBL
  Integrase_cat-core UniProtKB/TrEMBL
  Integrase_H2C2 UniProtKB/TrEMBL
  Rev_trsase/Diguanyl_cyclase UniProtKB/TrEMBL
  RNase_Zc3h12_NYN UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_domain UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
  RT_RNaseH_2 UniProtKB/TrEMBL
  ZC3H12/N4BP1_RNase_Reg UniProtKB/TrEMBL
NCBI Gene NYNRIN ENTREZGENE
PANTHER N4BP1-RELATED UniProtKB/TrEMBL
  PROTEIN NYNRIN UniProtKB/TrEMBL
Pfam Integrase_H2C2 UniProtKB/TrEMBL
  RNase_Zc3h12a UniProtKB/TrEMBL
  RT_RNaseH_2 UniProtKB/TrEMBL
PROSITE INTEGRASE UniProtKB/TrEMBL
  RNASE_H_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF53098 UniProtKB/TrEMBL
  SSF56672 UniProtKB/TrEMBL
UniProt A0A287B9G4_PIG UniProtKB/TrEMBL
  A0A5G2QEL3 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2RDT6_PIG UniProtKB/TrEMBL
  A0A8D0PBV1_PIG UniProtKB/TrEMBL
  A0A8D0PH67_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91003 ENTREZGENE