CCDC134 (coiled-coil domain containing 134)

Gene: CCDC134 (coiled-coil domain containing 134) Chlorocebus sabaeus

Analyze

Symbol:

CCDC134

Name:

coiled-coil domain containing 134

RGD ID:

18489859

Description:

INVOLVED IN angiogenesis (ortholog); embryonic hemopoiesis (ortholog); embryonic liver development (ortholog); ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Bone Fractures (ortholog); common variable immunodeficiency 4 (ortholog); FOUND IN cytosol (inferred); intracellular membrane-bounded organelle (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

coiled-coil domain-containing protein 134

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	24,332,293 - 24,358,056 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	24,332,316 - 24,357,583 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	101,050,699 - 101,079,923 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenylosuccinase lyase deficiency (ISO)

Bone Fractures (ISO)

common variable immunodeficiency 4 (ISO)

genetic disease (ISO)

Liver Neoplasms (ISO)

osteogenesis imperfecta type 22 (ISO)

osteogenesis imperfecta type 3 (ISO)

pre-malignant neoplasm (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA,ISO)

embryonic hemopoiesis (IEA,ISO)

embryonic liver development (IEA,ISO)

placenta development (IEA,ISO)

regulation of ossification (IEA)

ventricular system development (IEA,ISO)

Cellular Component

cytosol (IEA)

intracellular membrane-bounded organelle (IEA)

Molecular Function

protein binding (ISO)

References

Genomics

Comparative Map Data

CCDC134
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	24,332,293 - 24,358,056 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	24,332,316 - 24,357,583 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	101,050,699 - 101,079,923 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CCDC134
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	41,800,679 - 41,832,164 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	41,800,679 - 41,832,164 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	42,196,683 - 42,228,168 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	40,526,624 - 40,552,249 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	22	26,002,745 - 26,028,378 (+)	NCBI		Celera
Cytogenetic Map	22	q13.2	NCBI
HuRef	22	25,162,231 - 25,187,861 (+)	NCBI		HuRef
CHM1_1	22	42,156,707 - 42,182,315 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	42,279,285 - 42,310,775 (+)	NCBI		T2T-CHM13v2.0

Ccdc134
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	82,012,101 - 82,026,404 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	82,012,123 - 82,026,404 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	82,127,898 - 82,142,203 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	82,127,922 - 82,142,203 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	81,958,352 - 81,972,633 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	81,955,251 - 81,969,455 (+)	NCBI		MGSCv36	mm8
Celera	15	84,251,167 - 84,265,449 (+)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	38.47	NCBI

Ccdc134
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	115,526,537 - 115,539,155 (+)	NCBI		GRCr8
mRatBN7.2	7	113,644,557 - 113,659,050 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	113,644,639 - 113,659,050 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	115,403,041 - 115,414,538 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	117,626,544 - 117,638,041 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	117,595,985 - 117,607,482 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	123,362,471 - 123,376,930 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	123,364,312 - 123,376,221 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	123,345,979 - 123,360,343 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	120,505,741 - 120,517,685 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	109,961,749 - 109,973,693 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

Ccdc134
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	27,249,272 - 27,265,635 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	27,248,879 - 27,265,635 (+)	NCBI	ChiLan1.0	ChiLan1.0

CCDC134
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	51,629,631 - 51,661,993 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	54,328,938 - 54,360,324 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	22,692,503 - 22,724,871 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	40,778,244 - 40,810,549 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	40,778,254 - 40,804,191 (+)	Ensembl	panpan1.1		panPan2

Ccdc134
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	7,165,338 - 7,185,212 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	178,390 - 195,806 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	180,135 - 195,599 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC134
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	6,785,947 - 6,799,913 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	6,785,957 - 6,800,816 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Ccdc134
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	6,871,911 - 6,885,396 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	6,872,192 - 6,885,435 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	27		11
Low	9	20	49
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007975928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038007363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000003777 ⟹ ENSCSAP00000002051

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	19	24,332,316 - 24,357,583 (+)	Ensembl

RefSeq Acc Id:

XM_007975928 ⟹ XP_007974119

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	19	24,332,293 - 24,358,056 (+)	NCBI
Vero_WHO_p1.0	NW_023666045	101,050,710 - 101,079,923 (-)	NCBI

Sequence:

show sequence

AGCGCGGTGGGCGGGACGGCGCTCGGCGGTCTGCTCTTGGTTGCTAGCTGGGTGCTGCTGCTTT
CAGTGCCTTTGCTGTTAGTCTCTTGGAACTTCGAGCCCAGCTGCTCGCATAGGACTCGGCCACC
TGCCCTTCCTGCACTGCCTGGCCAGCTCAAGAGGTTTGGATATGGACCTTCTTCAGTTCCTGGC
CTTCCTCTTTGTCTTGCTTTTGTCTGGGATGGGAGCCACAGGCACCTTGAGGACTTCCCTGGAC
CCAAGCCTGGAGATCTACAAGAAGATGTTTGAGGTGAAGCGGCGGGAGCAGCTGTTGGCACTGA
AGAACCTGGCACAGCTGAACGACATCCATCAGCAGTACAAGATCCTTGATGTCATGCTCAAGGG
GCTCTTTAAGGTGCTGGAGGACTCCCGGACAGTGCTCACCGCTGCTGATGTGCTCCCAGATGGG
CCTTTCCCCCAGGACGAGAAGCTAAAGGATGCTTTCTCCCATGTGGTGGAGAACACGGCCTTCT
TCGGCGATGTGGTGCTGCGCTTCCCAAGGATTGTGCACTATTACTTTGACCACAACTCCAACTG
GAACCTCCTCATCCGCTGGGGCATCAGTTTCTGCAACCAGACGGGCGTCTTCGACCAGGGGCCC
CACTCGCCCATCCTCAGCCTGATGGCCCAGGAACTGGGGATCAGTGAGAAAGACTCCGACTTCC
AGAACCCATTTAAAATCGACCGCACAGAGTTCATTCCCAGCACTGACCCTTTCCAGAAGGCCTT
GAGAGAAGAAGAGAAACGCCGGAAGAAAGAGGAAAAGCGGAAAGAGATCCGAAAAGGCCCAAGG
ATCTCCAGATCCCAGTCTGAGTTATAGCCCTGGAGCAGCTCAGGGCTCAAGGGGCCACAAGGAG
GCAGGTCGGGAGGAAGAAGAGGTGGAGATGTGGTTGTGGTGGAGAGCACCAGCCAGCCCCTTCC
AGAAGGAGAGGCCACATTTTCCCAGCCCCCCGGAGCTGGGTCTGAGCCCTGGCTGAAGGGACTG
AGCCTCACGCTGGCTTTTCTCTCAGGGGCCTCCTGCTGAAGAGGCCTTCAGAGGACTTTATACT
GGAAATATGACCCTGTGCAGACTGCTGGGGGAGGCAGGGGGATGCCTGCCTGGACTCTTTTGGT
GGCTGAAAACCTCTGGCCAGCTGGCTTCCACTCTTGGTGGGGAAGCAGCAGAAGTAGGTTCTGA
GCCACAGGTAAGGATGCCACCCTGCGGCTGGCCCCATGGTGTCACAGAGCTGCCCGGCACAGGT
CCCAGCCCCTCTGCAGAGACACAATAAAAGCCAGCAGACCCTTTGGACCAAC

hide sequence

RefSeq Acc Id:

XM_038007363 ⟹ XP_037863291

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666045	101,050,699 - 101,079,923 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007974119	(Get FASTA)	NCBI Sequence Viewer
	XP_037863291	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002051
	ENSCSAP00000002051.1

RefSeq Acc Id:	XP_007974119 ⟸ XM_007975928
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R0B2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000002051 ⟸ ENSCSAT00000003777

RefSeq Acc Id:	XP_037863291 ⟸ XM_038007363
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000005737	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000003777.1	UniProtKB/TrEMBL
InterPro	Coiled-coil_dom_con_pro_134	UniProtKB/TrEMBL
KEGG Report	csab:103223396	UniProtKB/TrEMBL
NCBI Gene	CCDC134	ENTREZGENE
PANTHER	COILED-COIL DOMAIN-CONTAINING PROTEIN 134	UniProtKB/TrEMBL
	PTHR14735	UniProtKB/TrEMBL
Pfam	ERK-JNK_inhib	UniProtKB/TrEMBL
UniProt	A0A0D9R0B2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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