CBX7 (chromobox 7) - Rat Genome Database

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Gene: CBX7 (chromobox 7) Chlorocebus sabaeus
Analyze
Symbol: CBX7
Name: chromobox 7
RGD ID: 18711372
Description: ENCODES a protein that exhibits chromatin binding (ortholog); methylated histone binding (ortholog); single-stranded RNA binding (ortholog); INVOLVED IN developmental process involved in reproduction (ortholog); positive regulation of transcription elongation by RNA polymerase II (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); B-cell lymphoma (ortholog); breast cancer (ortholog); FOUND IN heterochromatin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromobox protein homolog 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,776,618 - 21,798,525 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,775,931 - 21,798,309 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045103,958,387 - 103,980,295 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CBX7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,776,618 - 21,798,525 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,775,931 - 21,798,309 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045103,958,387 - 103,980,295 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CBX7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,130,772 - 39,152,680 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,120,167 - 39,152,680 (-)EnsemblGRCh38hg38GRCh38
GRCh372239,526,777 - 39,548,685 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,856,723 - 37,878,484 (-)NCBINCBI36Build 36hg18NCBI36
Build 342237,851,280 - 37,873,038NCBI
Celera2223,328,820 - 23,350,581 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,493,890 - 22,515,575 (-)NCBIHuRef
CHM1_12239,485,611 - 39,507,403 (-)NCBICHM1_1
T2T-CHM13v2.02239,601,155 - 39,623,071 (-)NCBIT2T-CHM13v2.0
Cbx7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,800,005 - 79,855,344 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,800,008 - 79,855,320 (-)EnsemblGRCm39 Ensembl
GRCm381579,915,804 - 79,971,143 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,915,807 - 79,971,119 (-)EnsemblGRCm38mm10GRCm38
MGSCv371579,746,237 - 79,763,076 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,740,244 - 79,759,866 (-)NCBIMGSCv36mm8
Celera1582,033,986 - 82,050,640 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
Cbx7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,341,030 - 113,358,716 (-)NCBIGRCr8
mRatBN7.27111,460,656 - 111,479,231 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,460,656 - 111,477,973 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,208,676 - 113,225,978 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,432,223 - 115,449,524 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,401,568 - 115,418,871 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,136,067 - 121,153,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,136,058 - 121,153,383 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,126,405 - 121,144,401 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,148,413 - 118,165,701 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,182,643 - 118,199,931 (-)NCBI
Celera7107,790,484 - 107,807,779 (-)NCBICelera
Cytogenetic Map7q34NCBI
Cbx7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,086,186 - 25,100,039 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,079,627 - 25,100,039 (-)NCBIChiLan1.0ChiLan1.0
CBX7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,978,435 - 49,000,373 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,669,911 - 51,691,852 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,037,529 - 20,059,459 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,854,049 - 37,876,861 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,854,056 - 37,876,084 (-)Ensemblpanpan1.1panPan2
CBX7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,876,022 - 25,896,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,876,016 - 25,893,501 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,810,682 - 25,832,138 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,627,291 - 26,648,764 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,627,343 - 26,648,764 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,340,710 - 26,362,175 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,661,555 - 26,681,886 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,836,680 - 26,858,133 (+)NCBIUU_Cfam_GSD_1.0
Cbx7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,400,883 - 9,418,070 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,410,308 - 2,428,682 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,411,171 - 2,428,484 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBX7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,070,353 - 9,087,634 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,070,312 - 9,090,467 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,355,114 - 6,372,426 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cbx7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247529,133,569 - 9,151,934 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247529,133,587 - 9,151,216 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 33 1 56
Low 3 19 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000004401   ⟹   ENSCSAP00000002655
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1921,775,931 - 21,798,309 (-)Ensembl
RefSeq Acc Id: XM_007975825   ⟹   XP_007974016
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11921,776,623 - 21,798,522 (-)NCBI
Vero_WHO_p1.0NW_023666045103,958,392 - 103,980,295 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007975826   ⟹   XP_007974017
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11921,776,618 - 21,798,525 (-)NCBI
Vero_WHO_p1.0NW_023666045103,958,391 - 103,980,295 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038007422   ⟹   XP_037863350
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666045103,958,388 - 103,980,295 (+)NCBI
RefSeq Acc Id: XM_038007423   ⟹   XP_037863351
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666045103,958,387 - 103,980,295 (+)NCBI
RefSeq Acc Id: XM_038007424   ⟹   XP_037863352
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666045103,958,389 - 103,980,295 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007974017   ⟸   XM_007975826
- Peptide Label: isoform X4
- UniProtKB: A0A0D9R216 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007974016   ⟸   XM_007975825
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000002655   ⟸   ENSCSAT00000004401
RefSeq Acc Id: XP_037863351   ⟸   XM_038007423
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037863350   ⟸   XM_038007422
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037863352   ⟸   XM_038007424
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006361 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004401.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
InterPro CBX7 UniProtKB/TrEMBL
  CBX7_C UniProtKB/TrEMBL
  Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_dom_subgr UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
NCBI Gene CBX7 ENTREZGENE
PANTHER CHROMOBOX PROTEIN HOMOLOG 7 UniProtKB/TrEMBL
  PTHR47277 UniProtKB/TrEMBL
Pfam CBX7_C UniProtKB/TrEMBL
  Chromo UniProtKB/TrEMBL
PRINTS CHROMODOMAIN UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
SMART CHROMO UniProtKB/TrEMBL
Superfamily-SCOP SSF54160 UniProtKB/TrEMBL
UniProt A0A0D9R216 ENTREZGENE, UniProtKB/TrEMBL