HTR2C (5-hydroxytryptamine receptor 2C) - Rat Genome Database

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Gene: HTR2C (5-hydroxytryptamine receptor 2C) Chlorocebus sabaeus
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Symbol: HTR2C
Name: 5-hydroxytryptamine receptor 2C
RGD ID: 18651762
Description: ENCODES a protein that exhibits 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding (ortholog); G protein-coupled serotonin receptor activity (ortholog); Gq/11-coupled serotonin receptor activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); behavioral fear response (ortholog); behavioral response to nicotine (ortholog); ASSOCIATED WITH alcohol use disorder (ortholog); anxiety disorder (ortholog); autistic disorder (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); G protein-coupled serotonin receptor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X102,190,355 - 102,499,928 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX102,325,731 - 102,497,278 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606527,537,759 - 27,837,340 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HTR2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X102,190,355 - 102,499,928 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX102,325,731 - 102,497,278 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606527,537,759 - 27,837,340 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
HTR2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X114,584,086 - 114,910,061 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX114,584,078 - 114,910,061 (+)EnsemblGRCh38hg38GRCh38
GRCh37X113,818,559 - 114,144,624 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X113,724,807 - 114,050,880 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X113,641,530 - 113,967,604NCBI
CeleraX114,253,715 - 114,579,778 (+)NCBICelera
Cytogenetic MapXq23NCBI
HuRefX103,403,272 - 103,731,741 (+)NCBIHuRef
CHM1_1X113,729,484 - 114,055,500 (+)NCBICHM1_1
T2T-CHM13v2.0X112,992,593 - 113,318,748 (+)NCBIT2T-CHM13v2.0
Htr2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X145,745,509 - 145,980,273 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX145,745,509 - 145,980,273 (+)EnsemblGRCm39 Ensembl
GRCm38X146,962,464 - 147,197,277 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX146,962,513 - 147,197,277 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X143,397,056 - 143,631,820 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X142,208,881 - 142,443,644 (+)NCBIMGSCv36mm8
CeleraX130,902,904 - 131,136,225 (+)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX68.46NCBI
Htr2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X115,453,190 - 115,682,325 (+)NCBIGRCr8
mRatBN7.2X110,640,777 - 110,870,288 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX110,641,153 - 110,870,287 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX112,734,293 - 112,956,059 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X116,233,146 - 116,454,918 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X113,792,877 - 114,014,236 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X118,084,520 - 118,318,040 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX118,084,890 - 118,318,039 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X118,226,113 - 118,460,830 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X31,012,921 - 31,244,127 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X31,069,048 - 31,185,684 (-)NCBI
CeleraX109,958,913 - 110,179,824 (+)NCBICelera
Cytogenetic MapXq34NCBI
Htr2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955490910,415 - 1,126,373 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955490912,615 - 1,126,347 (-)NCBIChiLan1.0ChiLan1.0
HTR2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X114,026,594 - 114,352,146 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X114,030,203 - 114,355,755 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X103,673,172 - 103,999,133 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X114,169,823 - 114,503,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX114,199,485 - 114,503,201 (+)Ensemblpanpan1.1panPan2
HTR2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X87,342,800 - 87,641,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX87,342,792 - 87,638,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX73,595,073 - 73,759,737 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X89,055,367 - 89,357,473 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX89,055,355 - 89,357,011 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X86,633,342 - 86,797,977 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X88,307,583 - 88,472,268 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X88,140,047 - 88,305,373 (+)NCBIUU_Cfam_GSD_1.0
Htr2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X86,426,392 - 86,655,882 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364991,004,732 - 1,109,377 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364991,002,083 - 1,109,446 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTR2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX94,053,456 - 94,313,355 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X94,053,415 - 94,313,352 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X108,811,549 - 108,871,722 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2X108,566,657 - 108,733,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Htr2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249401,040,911 - 1,157,057 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249401,040,744 - 1,299,266 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSCSAT00000006711   ⟹   ENSCSAP00000004910
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblX102,325,731 - 102,497,278 (+)Ensembl
RefSeq Acc Id: XM_007992625   ⟹   XP_007990816
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X102,190,521 - 102,499,928 (+)NCBI
Vero_WHO_p1.0NW_02366606527,537,759 - 27,837,340 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007992626   ⟹   XP_007990817
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X102,190,355 - 102,499,928 (+)NCBI
Vero_WHO_p1.0NW_02366606527,537,765 - 27,835,772 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007990816 (Get FASTA)   NCBI Sequence Viewer  
  XP_007990817 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004910
  ENSCSAP00000004910.1
RefSeq Acc Id: XP_007990817   ⟸   XM_007992626
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007990816   ⟸   XM_007992625
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R8H1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000004910   ⟸   ENSCSAT00000006711


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008651 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006711.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 5HT2C_rcpt UniProtKB/TrEMBL
  5HT_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report csab:103232513 UniProtKB/TrEMBL
NCBI Gene HTR2C ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR UniProtKB/TrEMBL
  PTHR24247:SF32 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS 5HT2CRECEPTR UniProtKB/TrEMBL
  5HTRECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9R8H1 ENTREZGENE, UniProtKB/TrEMBL