IER2 (immediate early response 2) - Rat Genome Database

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Gene: IER2 (immediate early response 2) Chlorocebus sabaeus
Analyze
Symbol: IER2
Name: immediate early response 2
RGD ID: 18526926
Description: INVOLVED IN neuron differentiation (ortholog); response to fibroblast growth factor (ortholog); ASSOCIATED WITH alpha-mannosidosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog); childhood acute myeloid leukemia (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: immediate early response gene 2 protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,834,998 - 11,838,421 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl611,836,706 - 11,837,377 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660747,945,206 - 7,948,333 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
IER2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,834,998 - 11,838,421 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl611,836,706 - 11,837,377 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660747,945,206 - 7,948,333 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IER2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381913,150,411 - 13,154,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1913,150,411 - 13,154,911 (+)EnsemblGRCh38hg38GRCh38
GRCh371913,261,225 - 13,265,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361913,122,282 - 13,126,722 (+)NCBINCBI36Build 36hg18NCBI36
Build 341913,122,281 - 13,126,716NCBI
Celera1913,151,680 - 13,156,120 (+)NCBICelera
Cytogenetic Map19p13.13NCBI
HuRef1912,833,675 - 12,838,116 (+)NCBIHuRef
CHM1_11913,262,236 - 13,266,676 (+)NCBICHM1_1
T2T-CHM13v2.01913,275,624 - 13,280,125 (+)NCBIT2T-CHM13v2.0
Ier2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,387,960 - 85,389,481 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl885,387,960 - 85,389,483 (-)EnsemblGRCm39 Ensembl
GRCm38884,661,331 - 84,662,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl884,661,331 - 84,662,854 (-)EnsemblGRCm38mm10GRCm38
MGSCv37887,185,230 - 87,186,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36887,549,656 - 87,552,953 (-)NCBIMGSCv36mm8
Celera888,961,236 - 88,962,757 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.02NCBI
Ier2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81940,399,373 - 40,400,897 (+)NCBIGRCr8
mRatBN7.21923,494,551 - 23,496,075 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,494,184 - 23,499,211 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1930,317,473 - 30,318,997 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,971,850 - 30,973,374 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01933,194,540 - 33,196,064 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01925,774,146 - 25,775,670 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,774,143 - 25,775,659 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,750,509 - 36,752,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41925,159,276 - 25,160,800 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11925,164,101 - 25,165,622 (+)NCBI
Celera1923,048,157 - 23,049,681 (+)NCBICelera
Cytogenetic Map19q11NCBI
Ier2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541532,159,935 - 32,160,624 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541532,159,762 - 32,161,530 (+)NCBIChiLan1.0ChiLan1.0
IER2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22018,081,380 - 18,085,241 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11917,082,479 - 17,085,886 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01912,714,804 - 12,718,213 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11913,449,491 - 13,452,925 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1913,452,239 - 13,452,910 (+)Ensemblpanpan1.1panPan2
IER2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,071,243 - 49,074,184 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,072,234 - 49,072,902 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2048,944,380 - 48,946,236 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02049,588,863 - 49,590,720 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2049,588,864 - 49,590,663 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12048,800,441 - 48,802,297 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,226,806 - 49,228,663 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,469,195 - 49,471,051 (-)NCBIUU_Cfam_GSD_1.0
Ier2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,174,816 - 208,177,770 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366592,178,312 - 2,178,983 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366592,176,962 - 2,179,900 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IER2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl265,909,651 - 65,912,445 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1265,909,638 - 65,912,491 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,210,147 - 66,211,956 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ier2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624901684,966 - 685,652 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624901684,313 - 686,488 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 18 30
Low 2 30
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007995477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000018929   ⟹   ENSCSAP00000018358
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl611,836,706 - 11,837,377 (+)Ensembl
RefSeq Acc Id: XM_007995477   ⟹   XP_007993668
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1611,834,998 - 11,838,421 (+)NCBI
Vero_WHO_p1.0NW_0236660747,945,206 - 7,948,333 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007993668 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018358
  ENSCSAP00000018358.1
Reference Protein Sequences
RefSeq Acc Id: XP_007993668   ⟸   XM_007995477
- UniProtKB: A0A0D9SBW9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000018358   ⟸   ENSCSAT00000018929


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018839 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018929.1 UniProtKB/TrEMBL
InterPro IER UniProtKB/TrEMBL
KEGG Report csab:103234013 UniProtKB/TrEMBL
NCBI Gene IER2 ENTREZGENE
PANTHER IMMEDIATE EARLY RESPONSE GENE 2 PROTEIN UniProtKB/TrEMBL
  PTHR15895 UniProtKB/TrEMBL
Pfam IER UniProtKB/TrEMBL
UniProt A0A0D9SBW9 ENTREZGENE, UniProtKB/TrEMBL