SNX10 (sorting nexin 10) - Rat Genome Database

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Gene: SNX10 (sorting nexin 10) Chlorocebus sabaeus
Analyze
Symbol: SNX10
Name: sorting nexin 10
RGD ID: 18536144
Description: ENCODES a protein that exhibits 1-phosphatidylinositol binding (inferred); ATPase binding (inferred); lipid binding (inferred); INVOLVED IN bone mineralization involved in bone maturation (ortholog); bone remodeling (ortholog); bone resorption (ortholog); ASSOCIATED WITH autosomal recessive osteopetrosis 8 (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN apical cytoplasm (inferred); centrosome (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sorting nexin-10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,999,253 - 32,044,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,998,277 - 32,081,843 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604272,631,259 - 72,716,109 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SNX10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,999,253 - 32,044,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,998,277 - 32,081,843 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604272,631,259 - 72,716,109 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SNX10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38726,291,862 - 26,374,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl726,291,862 - 26,374,383 (+)EnsemblGRCh38hg38GRCh38
GRCh37726,331,482 - 26,414,003 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36726,298,040 - 26,380,474 (+)NCBINCBI36Build 36hg18NCBI36
Build 34726,104,754 - 26,187,187NCBI
Celera726,320,523 - 26,402,976 (+)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef726,213,196 - 26,295,663 (+)NCBIHuRef
CHM1_1726,331,091 - 26,413,549 (+)NCBICHM1_1
T2T-CHM13v2.0726,427,536 - 26,510,069 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2726,382,693 - 26,465,116 (+)NCBI
Snx10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39651,500,882 - 51,567,659 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl651,500,881 - 51,567,659 (+)EnsemblGRCm39 Ensembl
GRCm38651,523,900 - 51,590,679 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl651,523,901 - 51,590,679 (+)EnsemblGRCm38mm10GRCm38
MGSCv37651,473,902 - 51,540,669 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36651,474,106 - 51,520,253 (+)NCBIMGSCv36mm8
Celera652,041,831 - 52,108,565 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map624.95NCBI
Snx10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8481,943,262 - 82,007,667 (+)NCBIGRCr8
mRatBN7.2480,612,648 - 80,677,005 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl480,612,669 - 80,676,996 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx485,837,043 - 85,902,896 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0481,612,448 - 81,678,303 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,044,763 - 80,107,193 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0481,311,490 - 81,375,248 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl481,311,490 - 81,374,158 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04145,977,387 - 146,041,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4479,789,556 - 79,853,215 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1480,065,685 - 80,129,343 (+)NCBI
Celera475,513,406 - 75,574,707 (+)NCBICelera
Cytogenetic Map4q24NCBI
Snx10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541028,137,426 - 28,178,814 (+)NCBIChiLan1.0ChiLan1.0
SNX10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2631,119,435 - 31,201,532 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1779,444,161 - 79,526,258 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0726,935,357 - 27,017,461 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1726,537,519 - 26,618,862 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl726,537,189 - 26,620,720 (+)Ensemblpanpan1.1panPan2
SNX10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11439,567,701 - 39,642,475 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1439,567,471 - 39,640,872 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,058,554 - 39,132,699 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01439,506,523 - 39,581,109 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1439,506,054 - 39,581,109 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11439,621,497 - 39,695,665 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01439,308,572 - 39,382,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01439,659,123 - 39,733,270 (+)NCBIUU_Cfam_GSD_1.0
Snx10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511883,837,104 - 83,901,879 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,048,691 - 3,114,876 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,048,801 - 3,113,610 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1846,064,580 - 46,142,945 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11846,064,575 - 46,142,983 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,838,880 - 50,917,745 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Snx10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247394,209,036 - 4,233,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247394,210,840 - 4,274,768 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SNX10
1158 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000012286   ⟹   ENSCSAP00000010328
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2131,998,277 - 32,081,843 (-)Ensembl
RefSeq Acc Id: XM_007981823   ⟹   XP_007980014
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12131,999,253 - 32,025,641 (-)NCBI
Vero_WHO_p1.0NW_02366604272,631,260 - 72,716,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007981824   ⟹   XP_007980015
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12131,999,253 - 32,044,967 (-)NCBI
Vero_WHO_p1.0NW_02366604272,667,852 - 72,716,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007981825   ⟹   XP_007980016
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12131,999,253 - 32,015,520 (-)NCBI
Vero_WHO_p1.0NW_02366604272,699,624 - 72,716,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038004760   ⟹   XP_037860688
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604272,631,259 - 72,716,109 (+)NCBI
RefSeq Acc Id: XM_038004761   ⟹   XP_037860689
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604272,684,392 - 72,716,109 (+)NCBI
RefSeq Acc Id: XP_007980015   ⟸   XM_007981824
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RNY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007980014   ⟸   XM_007981823
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RNY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007980016   ⟸   XM_007981825
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000010328   ⟸   ENSCSAT00000012286
RefSeq Acc Id: XP_037860688   ⟸   XM_038004760
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RNY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037860689   ⟸   XM_038004761
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RNY9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014190 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012286.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
InterPro Phox UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  SNX10/11 UniProtKB/TrEMBL
KEGG Report csab:103226339 UniProtKB/TrEMBL
NCBI Gene SNX10 ENTREZGENE
PANTHER PTHR46209 UniProtKB/TrEMBL
  SORTING NEXIN-10 UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/TrEMBL
PROSITE PS50195 UniProtKB/TrEMBL
SMART SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF64268 UniProtKB/TrEMBL
UniProt A0A0D9RNY9 ENTREZGENE, UniProtKB/TrEMBL