SLC22A1 (solute carrier family 22 member 1) - Rat Genome Database

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Gene: SLC22A1 (solute carrier family 22 member 1) Chlorocebus sabaeus
Analyze
Symbol: SLC22A1
Name: solute carrier family 22 member 1
RGD ID: 18573282
Description: ENCODES a protein that exhibits acetylcholine transmembrane transporter activity (ortholog); dopamine:sodium symporter activity (ortholog); identical protein binding (ortholog); INVOLVED IN dopamine transport (ortholog); epinephrine transport (ortholog); establishment or maintenance of transmembrane electrochemical gradient (ortholog); PARTICIPATES IN lamivudine pharmacokinetics pathway; metformin pharmacokinetics pathway; tramadol pharmacokinetics pathway; ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); acute kidney failure (ortholog); asthma (ortholog); FOUND IN basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,744,600 - 87,780,846 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1387,745,023 - 87,781,073 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604060,132,123 - 60,167,647 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC22A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,744,600 - 87,780,846 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1387,745,023 - 87,781,073 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604060,132,123 - 60,167,647 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC22A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386160,121,815 - 160,158,718 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6160,121,815 - 160,158,718 (+)EnsemblGRCh38hg38GRCh38
GRCh376160,542,847 - 160,579,750 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,462,853 - 160,499,740 (+)NCBINCBI36Build 36hg18NCBI36
Build 346160,513,273 - 160,550,159NCBI
Celera6161,188,634 - 161,224,539 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6158,013,550 - 158,049,540 (+)NCBIHuRef
CHM1_16160,805,108 - 160,841,995 (+)NCBICHM1_1
T2T-CHM13v2.06161,367,910 - 161,404,908 (+)NCBIT2T-CHM13v2.0
Slc22a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,867,761 - 12,894,725 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1712,867,756 - 12,894,716 (-)EnsemblGRCm39 Ensembl
GRCm381712,648,874 - 12,675,838 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,648,869 - 12,675,829 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,841,740 - 12,868,704 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,492,232 - 12,519,196 (-)NCBIMGSCv36mm8
Celera1712,680,587 - 12,707,864 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.63NCBI
Slc22a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,624,339 - 50,651,437 (+)NCBIGRCr8
mRatBN7.2148,076,657 - 48,103,679 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl148,076,666 - 48,103,678 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,768,287 - 48,795,288 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,754,091 - 54,781,071 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,843,810 - 48,870,799 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,273,639 - 48,300,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,273,611 - 48,300,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,452,604 - 51,479,610 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,351,239 - 42,378,295 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,354,183 - 42,381,239 (+)NCBI
Celera143,876,335 - 43,903,290 (+)NCBICelera
Cytogenetic Map1q11NCBI
SLC22A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25180,216,337 - 180,263,051 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16178,125,295 - 178,169,671 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06158,004,545 - 158,046,428 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16163,014,522 - 163,054,818 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6163,014,663 - 163,054,681 (+)Ensemblpanpan1.1panPan2
SLC22A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,268,978 - 49,296,522 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,109,085 - 50,138,635 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,451,887 - 49,481,466 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,451,182 - 49,482,182 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,334,247 - 49,363,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0149,205,883 - 49,235,453 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,820,796 - 49,850,348 (+)NCBIUU_Cfam_GSD_1.0
Slc22a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,281,749 - 144,305,075 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,534,095 - 11,556,745 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,534,095 - 11,556,759 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC22A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,340,126 - 7,365,520 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,340,442 - 7,365,543 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,139,435 - 9,164,369 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 12
Below cutoff 11 5 9

Sequence


RefSeq Acc Id: ENSCSAT00000010470   ⟹   ENSCSAP00000008564
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1387,745,023 - 87,781,073 (+)Ensembl
RefSeq Acc Id: XM_008007741   ⟹   XP_008005932
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11387,744,600 - 87,780,846 (+)NCBI
Vero_WHO_p1.0NW_02366604060,132,123 - 60,167,647 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008007742   ⟹   XP_008005933
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11387,744,600 - 87,780,846 (+)NCBI
Vero_WHO_p1.0NW_02366604060,132,123 - 60,167,647 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008005932 (Get FASTA)   NCBI Sequence Viewer  
  XP_008005933 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008564
  ENSCSAP00000008564.1
RefSeq Acc Id: XP_008005932   ⟸   XM_008007741
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RIX5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005933   ⟸   XM_008007742
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000008564   ⟸   ENSCSAT00000010470


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012377 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010470.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS_dom UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  Orgcat_transp/SVOP UniProtKB/TrEMBL
  Sugar_transporter_CS UniProtKB/TrEMBL
KEGG Report csab:103240834 UniProtKB/TrEMBL
NCBI Gene SLC22A1 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 22 MEMBER UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 22 MEMBER 1 UniProtKB/TrEMBL
Pfam Sugar_tr UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
  SUGAR_TRANSPORT_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A0D9RIX5 ENTREZGENE, UniProtKB/TrEMBL