ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2) - Rat Genome Database

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Gene: ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2) Chlorocebus sabaeus
Analyze
Symbol: ZDHHC2
Name: zinc finger DHHC-type palmitoyltransferase 2
RGD ID: 18400717
Description: ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN positive regulation of AMPA glutamate receptor clustering (ortholog); positive regulation of endosome to plasma membrane protein transport (ortholog); positive regulation of long-term synaptic potentiation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); hereditary spastic paraplegia 53 (ortholog); FOUND IN postsynaptic density (ortholog); postsynaptic recycling endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: palmitoyltransferase ZDHHC2; zinc finger DHHC-type containing 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1815,241,100 - 15,311,431 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl815,270,598 - 15,303,323 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605226,967,582 - 27,040,155 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ZDHHC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1815,241,100 - 15,311,431 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl815,270,598 - 15,303,323 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605226,967,582 - 27,040,155 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ZDHHC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38817,156,482 - 17,224,799 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl817,156,482 - 17,224,799 (+)EnsemblGRCh38hg38GRCh38
GRCh37817,013,991 - 17,082,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36817,058,402 - 17,124,612 (+)NCBINCBI36Build 36hg18NCBI36
Build 34817,058,401 - 17,124,612NCBI
Celera815,979,980 - 16,046,302 (+)NCBICelera
Cytogenetic Map8p22NCBI
HuRef815,558,794 - 15,625,120 (+)NCBIHuRef
CHM1_1817,214,983 - 17,281,694 (+)NCBICHM1_1
T2T-CHM13v2.0817,424,063 - 17,492,390 (+)NCBIT2T-CHM13v2.0
Zdhhc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39840,876,526 - 40,946,178 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl840,876,856 - 40,963,309 (+)EnsemblGRCm39 Ensembl
GRCm38840,423,485 - 40,489,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl840,423,815 - 40,510,268 (+)EnsemblGRCm38mm10GRCm38
MGSCv37841,509,169 - 41,570,196 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36841,922,632 - 41,983,659 (+)NCBIMGSCv36mm8
Celera843,078,568 - 43,134,878 (+)NCBICelera
Cytogenetic Map8A4NCBI
cM Map823.89NCBI
Zdhhc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81658,511,931 - 58,581,530 (-)NCBIGRCr8
mRatBN7.21651,808,465 - 51,878,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1651,808,468 - 51,878,060 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1657,140,319 - 57,202,110 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01660,529,020 - 60,597,093 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01655,774,273 - 55,836,067 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01654,932,546 - 55,002,322 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1654,934,056 - 55,002,322 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01654,636,702 - 54,704,963 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41655,155,221 - 55,225,216 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11655,155,532 - 55,225,274 (-)NCBI
Celera1649,701,871 - 49,769,092 (-)NCBICelera
Cytogenetic Map16q12.1NCBI
Zdhhc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955463315,531 - 345,716 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955463315,531 - 345,712 (-)NCBIChiLan1.0ChiLan1.0
ZDHHC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2735,616,352 - 35,682,529 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1811,350,918 - 11,417,072 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0816,368,954 - 16,437,623 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1813,343,011 - 13,380,803 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl813,343,011 - 13,380,803 (+)Ensemblpanpan1.1panPan2
ZDHHC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11640,496,469 - 40,551,979 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1640,506,524 - 40,543,360 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1640,983,307 - 41,049,439 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01642,539,281 - 42,605,661 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11640,632,635 - 40,698,974 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01641,175,866 - 41,242,231 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01641,369,230 - 41,435,644 (+)NCBIUU_Cfam_GSD_1.0
Zdhhc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494338,862,294 - 38,926,352 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365736,216,078 - 6,282,052 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365736,216,084 - 6,280,142 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZDHHC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl174,855,345 - 4,928,664 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1174,855,129 - 4,928,109 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2175,249,301 - 5,321,889 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Zdhhc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476922,080,073 - 22,151,626 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476922,078,361 - 22,151,679 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 35 59
Low 1 20 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014877   ⟹   ENSCSAP00000012836
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl815,270,598 - 15,303,323 (+)Ensembl
RefSeq Acc Id: XM_007961729   ⟹   XP_007959920
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1815,241,100 - 15,311,431 (+)NCBI
Vero_WHO_p1.0NW_02366605226,967,582 - 27,040,155 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007961730   ⟹   XP_007959921
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1815,242,213 - 15,311,431 (+)NCBI
Vero_WHO_p1.0NW_02366605226,967,776 - 27,039,085 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007959920 (Get FASTA)   NCBI Sequence Viewer  
  XP_007959921 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012836
  ENSCSAP00000012836.1
Reference Protein Sequences
RefSeq Acc Id: XP_007959920   ⟸   XM_007961729
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RW47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007959921   ⟸   XM_007961730
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RW47 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012836   ⟸   ENSCSAT00000014877


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016782 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014877.1 UniProtKB/TrEMBL
InterPro Palmitoyltrfase_DHHC UniProtKB/TrEMBL
NCBI Gene ZDHHC2 ENTREZGENE
PANTHER PALMITOYLTRANSFERASE ZDHHC16 UniProtKB/TrEMBL
  PALMITOYLTRANSFERASE ZDHHC16 UniProtKB/TrEMBL
Pfam DHHC UniProtKB/TrEMBL
PROSITE DHHC UniProtKB/TrEMBL
UniProt A0A0D9RW47 ENTREZGENE, UniProtKB/TrEMBL