PDCD10 (programmed cell death 10) - Rat Genome Database

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Gene: PDCD10 (programmed cell death 10) Chlorocebus sabaeus
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Symbol: PDCD10
Name: programmed cell death 10
RGD ID: 18751208
Description: ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arteriovenous malformations of the brain (ortholog); cavernous hemangioma (ortholog); Central Nervous System Neoplasms (ortholog); FOUND IN cell periphery (ortholog); cytoplasm (ortholog); Golgi membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat extensin-like protein 5; LOC103221333; programmed cell death protein 10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11521,697,366 - 21,748,760 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1521,706,675 - 21,749,470 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606330,541,167 - 30,592,646 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PDCD10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11521,697,366 - 21,748,760 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1521,706,675 - 21,749,470 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606330,541,167 - 30,592,646 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PDCD10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383167,683,298 - 167,734,892 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3167,683,298 - 167,734,939 (-)EnsemblGRCh38hg38GRCh38
GRCh373167,401,086 - 167,452,680 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363168,884,388 - 168,935,345 (-)NCBINCBI36Build 36hg18NCBI36
Build 343168,884,398 - 168,935,332NCBI
Celera3165,800,144 - 165,851,087 (-)NCBICelera
Cytogenetic Map3q26.1NCBI
HuRef3164,771,770 - 164,822,713 (-)NCBIHuRef
CHM1_13167,364,579 - 167,415,523 (-)NCBICHM1_1
T2T-CHM13v2.03170,467,195 - 170,518,819 (-)NCBIT2T-CHM13v2.0
Pdcd10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39375,423,797 - 75,464,159 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl375,423,797 - 75,464,163 (-)EnsemblGRCm39 Ensembl
GRCm38375,516,490 - 75,556,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl375,516,490 - 75,556,856 (-)EnsemblGRCm38mm10GRCm38
MGSCv37375,320,412 - 75,360,721 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36375,602,416 - 75,642,726 (-)NCBIMGSCv36mm8
Celera375,581,629 - 75,621,940 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map333.76NCBI
Pdcd10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82162,602,516 - 162,644,690 (-)NCBIGRCr8
mRatBN7.22160,303,465 - 160,346,086 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2160,303,449 - 160,346,018 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2167,476,398 - 167,518,511 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02165,480,684 - 165,522,792 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02160,113,470 - 160,155,584 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02173,966,701 - 174,012,730 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2173,967,080 - 174,012,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02193,304,862 - 193,348,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42166,402,652 - 166,445,015 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12166,352,757 - 166,395,121 (-)NCBI
Celera2154,499,050 - 154,540,946 (-)NCBICelera
Cytogenetic Map2q32NCBI
Pdcd10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544816,864,031 - 16,887,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544816,866,577 - 16,887,215 (-)NCBIChiLan1.0ChiLan1.0
PDCD10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22165,583,937 - 165,635,162 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13165,588,664 - 165,639,889 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03164,703,909 - 164,755,085 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13172,760,923 - 172,811,900 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3172,760,923 - 172,811,430 (-)Ensemblpanpan1.1panPan2
PDCD10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13432,512,109 - 32,553,524 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3432,512,112 - 32,553,445 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3441,592,572 - 41,634,550 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03432,590,535 - 32,632,534 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3432,584,275 - 32,632,464 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13432,535,691 - 32,577,676 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03432,496,175 - 32,538,163 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03432,767,820 - 32,809,818 (-)NCBIUU_Cfam_GSD_1.0
Pdcd10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560298,930,028 - 98,971,364 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365934,651,114 - 4,692,534 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365934,650,624 - 4,693,387 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDCD10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13106,517,432 - 106,558,895 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113106,517,408 - 106,558,959 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213115,080,081 - 115,120,768 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pdcd10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473045,654,022 - 45,678,745 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473045,653,470 - 45,698,461 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000010595   ⟹   ENSCSAP00000008685
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1521,706,675 - 21,749,470 (+)Ensembl
RefSeq Acc Id: XM_007972176   ⟹   XP_007970367
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11521,697,376 - 21,748,760 (+)NCBI
Vero_WHO_p1.0NW_02366606330,541,167 - 30,592,646 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007972177   ⟹   XP_007970368
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11521,697,366 - 21,748,760 (+)NCBI
Vero_WHO_p1.0NW_02366606330,541,175 - 30,592,646 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037988589   ⟹   XP_037844517
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606330,541,189 - 30,592,646 (+)NCBI
RefSeq Acc Id: XM_037988590   ⟹   XP_037844518
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606330,541,597 - 30,592,646 (+)NCBI
RefSeq Acc Id: XM_037988591   ⟹   XP_037844519
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606330,541,188 - 30,592,646 (+)NCBI
RefSeq Acc Id: XM_037988592   ⟹   XP_037844520
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606330,541,645 - 30,592,646 (+)NCBI
RefSeq Acc Id: XP_007970368   ⟸   XM_007972177
- UniProtKB: A0A0D9RJ96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007970367   ⟸   XM_007972176
- UniProtKB: A0A0D9RJ96 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000008685   ⟸   ENSCSAT00000010595
RefSeq Acc Id: XP_037844519   ⟸   XM_037988591
- UniProtKB: A0A0D9RJ96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037844517   ⟸   XM_037988589
- UniProtKB: A0A0D9RJ96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037844518   ⟸   XM_037988590
- UniProtKB: A0A0D9RJ96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037844520   ⟸   XM_037988592
- UniProtKB: A0A0D9RJ96 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012498 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010595.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.12.70 UniProtKB/TrEMBL
  Nucleotidyltransferases domain 2 UniProtKB/TrEMBL
InterPro PDC10_dimerisation_sf UniProtKB/TrEMBL
  PDCD10 UniProtKB/TrEMBL
  PDCD10_N UniProtKB/TrEMBL
KEGG Report csab:103221296 UniProtKB/TrEMBL
NCBI Gene PDCD10 ENTREZGENE
PANTHER PROGRAMMED CELL DEATH PROTEIN 10 UniProtKB/TrEMBL
  PTHR13250 UniProtKB/TrEMBL
Pfam DUF1241 UniProtKB/TrEMBL
  PDCD10_N UniProtKB/TrEMBL
UniProt A0A0D9RJ96 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 PDCD10  programmed cell death 10  LOC103221333  leucine-rich repeat extensin-like protein 5  Data merged from RGD:18453687 737654 PROVISIONAL