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Gene: AXIN1 (axin 1) Chlorocebus sabaeus

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Symbol:

AXIN1

Name:

axin 1

RGD ID:

18530057

Description:

ENCODES a protein that exhibits armadillo repeat domain binding (ortholog); beta-catenin binding (ortholog); identical protein binding (ortholog); INVOLVED IN adult walking behavior (ortholog); embryonic skeletal joint morphogenesis (ortholog); erythrocyte homeostasis (ortholog); PARTICIPATES IN altered Wnt signaling, canonical pathway; colorectal cancer pathway; N-cadherin signaling pathway; ASSOCIATED WITH Caudal Duplication Anomaly (ortholog); colon cancer (ortholog); CRANIOMETADIAPHYSEAL OSTEOSCLEROSIS WITH HIP DYSPLASIA (ortholog); FOUND IN Golgi apparatus (ortholog); synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

axin-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AXIN1 (axin 1)	NCBI	Ortholog
Mus musculus (house mouse):	Axin1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Axin1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Axin1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AXIN1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AXIN1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Axin1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AXIN1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Axin1 (axin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	233,520 - 295,134 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	234,060 - 290,575 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	30,878,427 - 30,943,289 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	colon cancer	treatment	ISO	Axin1 (Rattus norvegicus)	9068941		RGD	PMID:28032729 and REF_RGD_ID:150530464
AXIN1	Green Monkey	esophagus squamous cell carcinoma	disease_progression	ISO	AXIN1 (Homo sapiens)	9068941	protein:decreased expression:esophagus (human)	RGD	PMID:12771989 and REF_RGD_ID:150530473
AXIN1	Green Monkey	hepatocellular carcinoma	disease_progression	ISO	AXIN1 (Homo sapiens)	9068941	associated with Hepatitis B more ...	RGD	PMID:26968103 and REF_RGD_ID:14402039
AXIN1	Green Monkey	hepatocellular carcinoma	disease_progression	ISO	AXIN1 (Homo sapiens)	9068941	protein:decreased expression:liver (human)	RGD	PMID:31514071 and REF_RGD_ID:150530482
AXIN1	Green Monkey	liver cirrhosis		ISO	AXIN1 (Homo sapiens)	9068941	protein:decreased expression:liver (human)	RGD	PMID:31514071 and REF_RGD_ID:150530482
AXIN1	Green Monkey	lung cancer	disease_progression	ISO	AXIN1 (Homo sapiens)	9068941	protein:decreased expression:lung (human)	RGD	PMID:21496867 and REF_RGD_ID:150530293
AXIN1	Green Monkey	lung cancer	disease_progression	ISO	AXIN1 (Homo sapiens)	9068941	DNA:hypermethylation	RGD	PMID:23192643 and REF_RGD_ID:150527862
AXIN1	Green Monkey	lung cancer	treatment	ISO	AXIN1 (Homo sapiens)	9068941	human cells in mouse model	RGD	PMID:23915259 more ...
AXIN1	Green Monkey	lung non-small cell carcinoma	disease_progression	ISO	AXIN1 (Homo sapiens)	9068941	protein:decreased expression:lung (human)	RGD	PMID:19735876 and REF_RGD_ID:150530290
AXIN1	Green Monkey	oral squamous cell carcinoma		ISO	AXIN1 (Homo sapiens)	9068941	mRNA:increased expression:oral epithelium (human)	RGD	PMID:21393552 and REF_RGD_ID:150530486
AXIN1	Green Monkey	oral squamous cell carcinoma	disease_progression	ISO	AXIN1 (Homo sapiens)	9068941	protein:decreased expression:oral epithelium (human)	RGD	PMID:17143481 and REF_RGD_ID:150530474
AXIN1	Green Monkey	urinary bladder cancer	susceptibility	ISO	AXIN1 (Homo sapiens)	9068941	DNA:SNPs:5'utr: (rs12921862 more ...	RGD	PMID:31143301 and REF_RGD_ID:150527861

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	Caudal Duplication Anomaly		ISO	AXIN1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Caudal duplication anomaly	ClinVar	PMID:25741868 and PMID:28492532
AXIN1	Green Monkey	CRANIOMETADIAPHYSEAL OSTEOSCLEROSIS WITH HIP DYSPLASIA		ISO	AXIN1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Craniometadiaphyseal osteosclerosis with hip dysplasia	ClinVar	PMID:25741868 and PMID:37582359
AXIN1	Green Monkey	epilepsy		ISO	AXIN1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Epilepsy	ClinVar	PMID:24463883 more ...
AXIN1	Green Monkey	hepatocellular carcinoma		ISO	AXIN1 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10700176 more ...
AXIN1	Green Monkey	Idiopathic Generalized Epilepsy		ISO	AXIN1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Idiopathic generalized epilepsy	ClinVar	PMID:28492532
AXIN1	Green Monkey	short-rib thoracic dysplasia 9 with or without polydactyly		ISO	AXIN1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Saldino-Mainzer syndrome	ClinVar	PMID:19370764 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	Caudal Duplication Anomaly		ISO	AXIN1 (Homo sapiens)	7240710		OMIM
AXIN1	Green Monkey	CRANIOMETADIAPHYSEAL OSTEOSCLEROSIS WITH HIP DYSPLASIA		ISO	AXIN1 (Homo sapiens)	7240710		OMIM
AXIN1	Green Monkey	hepatocellular carcinoma		ISO	AXIN1 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	adult walking behavior	acts_upstream_of_or_within	ISO	MGI:1856035	9068941		MGI	MGI:48782
AXIN1	Green Monkey	axial mesoderm development	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	axial mesoderm formation	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	beta-catenin destruction complex assembly	involved_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	canonical Wnt signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	cell development	involved_in	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	cytoplasmic microtubule organization	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	dorsal/ventral axis specification	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	dorsal/ventral pattern formation	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	embryonic skeletal joint morphogenesis	acts_upstream_of_or_within	ISO	MGI:1856035 and MGI:1856036	9068941		MGI	MGI:48782
AXIN1	Green Monkey	epigenetic programming in the zygotic pronuclei	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	erythrocyte homeostasis	acts_upstream_of_or_within	ISO	MGI:1856035	9068941		MGI	MGI:48782
AXIN1	Green Monkey	head development	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	hemoglobin metabolic process	acts_upstream_of_or_within	ISO	MGI:1856035	9068941		MGI	MGI:48782
AXIN1	Green Monkey	in utero embryonic development	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	negative regulation of canonical Wnt signaling pathway		ISO	Axin1 (Rattus norvegicus)	9068941		RGD	PMID:9482734 and REF_RGD_ID:632259
AXIN1	Green Monkey	negative regulation of canonical Wnt signaling pathway	involved_in	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	negative regulation of canonical Wnt signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	negative regulation of canonical Wnt signaling pathway	involved_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	negative regulation of canonical Wnt signaling pathway	involved_in	IEA	InterPro:IPR043581	150520179		InterPro	GO_REF:0000002
AXIN1	Green Monkey	negative regulation of fat cell differentiation	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	negative regulation of gene expression	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	negative regulation of protein metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	negative regulation of transcription elongation by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	negative regulation of Wnt signaling pathway	involved_in	IEA	ARBA:ARBA00027587	150520179		UniProt	GO_REF:0000117
AXIN1	Green Monkey	negative regulation of Wnt signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	nervous system process	acts_upstream_of_or_within	ISO	MGI:1856035	9068941		MGI	MGI:48782
AXIN1	Green Monkey	nucleocytoplasmic transport	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	positive regulation of JNK cascade	involved_in	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	positive regulation of JNK cascade	acts_upstream_of_or_within	ISO	MGI:1856035	9068941	PMID:18316368	MGI	PMID:18316368
AXIN1	Green Monkey	positive regulation of JUN kinase activity	acts_upstream_of_or_within	ISO	Axin1 (Mus musculus)	9068941	PMID:12878610 and PMID:15579909	MGI	PMID:12878610 and PMID:15579909
AXIN1	Green Monkey	positive regulation of JUN kinase activity	acts_upstream_of_or_within	ISO	Axin1 (Mus musculus)	9068941	PMID:12878610	MGI	PMID:12878610
AXIN1	Green Monkey	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	involved_in	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	positive regulation of protein catabolic process	involved_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	positive regulation of protein kinase activity		ISO	Axin1 (Rattus norvegicus)	9068941		RGD	PMID:15228590 and REF_RGD_ID:1304344
AXIN1	Green Monkey	positive regulation of protein kinase activity	involved_in	ISO	Axin1 (Mus musculus)	9068941	PMID:15526030	CACAO	PMID:15526030
AXIN1	Green Monkey	positive regulation of protein phosphorylation	acts_upstream_of_or_within	ISO	Axin1 (Mus musculus)	9068941	PMID:10330403	MGI	PMID:10330403
AXIN1	Green Monkey	positive regulation of protein ubiquitination	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	positive regulation of protein ubiquitination	involved_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	positive regulation of transforming growth factor beta receptor signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	positive regulation of ubiquitin-dependent protein catabolic process	involved_in	ISO	Axin1 (Rattus norvegicus)	9068941	PMID:10228155	BHF-UCL	PMID:10228155 and REF_RGD_ID:8553327
AXIN1	Green Monkey	positive regulation of ubiquitin-dependent protein catabolic process	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	post-anal tail morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein catabolic process	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein polyubiquitination	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein-containing complex assembly	involved_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	regulation of canonical Wnt signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	regulation of protein phosphorylation	acts_upstream_of_or_within	ISO	MGI:94941	9068941	PMID:14734535	MGI	PMID:14734535
AXIN1	Green Monkey	response to quercetin		ISO	Axin1 (Rattus norvegicus)	9068941		RGD	PMID:28032729 and REF_RGD_ID:150530464
AXIN1	Green Monkey	sensory perception of sound	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	Wnt signaling pathway	involved_in	IEA	UniProtKB-KW:KW-0879	150520179		UniProt	GO_REF:0000043
AXIN1	Green Monkey	Wnt signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	beta-catenin destruction complex	part_of	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	beta-catenin destruction complex	part_of	IEA	UniProtKB:O15169 more ...	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	cell cortex	located_in	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	cell periphery	located_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
AXIN1	Green Monkey	cytoplasm	located_in	IEA	UniProtKB:O15169 more ...	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	cytoplasmic vesicle	located_in	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	Golgi apparatus	located_in	ISO	Axin1 (Rattus norvegicus)	9068941	PMID:16890161	BHF-UCL	PMID:16890161 and REF_RGD_ID:8554078
AXIN1	Green Monkey	lateral plasma membrane	located_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
AXIN1	Green Monkey	microtubule cytoskeleton	located_in	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	nucleolus	located_in	IEA	UniProtKB:A0A0S2Z4R0 more ...	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	nucleus	located_in	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043
AXIN1	Green Monkey	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
AXIN1	Green Monkey	nucleus	located_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	perinuclear region of cytoplasm	located_in	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	plasma membrane	located_in	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	150520179		UniProt	GO_REF:0000044
AXIN1	Green Monkey	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	150520179		UniProt	GO_REF:0000043
AXIN1	Green Monkey	plasma membrane	located_in	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein-containing complex	part_of	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	synapse	is_active_in	ISO	Axin1 (Rattus norvegicus)	9068941	PMID:15228590	SynGO	PMID:15228590 and REF_RGD_ID:1304344
AXIN1	Green Monkey	Wnt signalosome	part_of	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	armadillo repeat domain binding	enables	ISO	Axin1 (Rattus norvegicus)	9068941	PMID:9482734	BHF-UCL	PMID:9482734 and REF_RGD_ID:632259
AXIN1	Green Monkey	beta-catenin binding		ISO	Ctnnb1 (Rattus norvegicus)	9068941		RGD	PMID:15228590 and REF_RGD_ID:1304344
AXIN1	Green Monkey	beta-catenin binding	enables	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	beta-catenin binding	enables	IEA	UniProtKB:O15169 more ...	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	enzyme binding	enables	IEA	ARBA:ARBA00026481	150520179		UniProt	GO_REF:0000117
AXIN1	Green Monkey	enzyme binding	enables	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	I-SMAD binding	enables	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	I-SMAD binding	enables	IEA	UniProtKB:O15169 more ...	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	identical protein binding		ISO	Axin1 (Rattus norvegicus)	9068941	homooligomerization	RGD	PMID:10330181 and REF_RGD_ID:4108508
AXIN1	Green Monkey	identical protein binding	enables	IEA	UniProtKB:O15169 more ...	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	identical protein binding	enables	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	molecular adaptor activity	enables	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	molecular adaptor activity	enables	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	p53 binding	enables	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein binding	enables	ISO	PR:Q60838 and PR:Q80Y83	9068941	PMID:15579909	MGI	PMID:15579909
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P35222 and UniProtKB:P49841	9068941	PMID:12421363	IntAct	PMID:12421363
AXIN1	Green Monkey	protein binding	enables	ISO	PR:Q9QXZ0	9068941	PMID:16815997	MGI	PMID:16815997
AXIN1	Green Monkey	protein binding	enables	ISO	PR:Q02248	9068941	PMID:15327768	MGI	PMID:15327768
AXIN1	Green Monkey	protein binding	enables	ISO	MGI:1346872 more ...	9068941	PMID:17681137	MGI	PMID:17681137
AXIN1	Green Monkey	protein binding	enables	ISO	PR:Q9D0L1	9068941	PMID:19141611	MGI	PMID:19141611
AXIN1	Green Monkey	protein binding	enables	ISO	PR:P51141	9068941	PMID:11113207	MGI	PMID:11113207
AXIN1	Green Monkey	protein binding	enables	ISO	PR:Q91VN0 and PR:Q9WV60	9068941	PMID:18632848	MGI	PMID:18632848
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q9PTP2	9068941	PMID:10688669	UniProt	PMID:10688669
AXIN1	Green Monkey	protein binding	enables	ISO	Axin1 (Mus musculus)	9068941	PMID:10318824	MGI	PMID:10318824
AXIN1	Green Monkey	protein binding	enables	ISO	PR:P63330	9068941	PMID:9920888	MGI	PMID:9920888
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O95271	9068941	PMID:19759537	IntAct	PMID:19759537
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P46937 and UniProtKB:Q9EPK5	9068941	PMID:24976009	IntAct	PMID:24976009
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P35222	9068941	PMID:20531388	IntAct	PMID:20531388
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q6PFX9	9068941	PMID:22307604	DisProt	PMID:22307604
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q8C4Q6	9068941	PMID:17681137	UniProt	PMID:17681137
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49841	9068941	PMID:20368287 and PMID:22682247	IntAct	PMID:20368287 and PMID:22682247
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O75197	9068941	PMID:11336703	ParkinsonsUK-UCL	PMID:11336703
AXIN1	Green Monkey	protein binding	enables	ISO	PR:Q91VN0	9068941	PMID:19075000	MGI	PMID:19075000
AXIN1	Green Monkey	protein binding	enables	ISO	PR:O08648 and PR:P53349	9068941	PMID:12878610	MGI	PMID:12878610
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O43255 and UniProtKB:Q8IUQ4	9068941	PMID:28546513	UniProt	PMID:28546513
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49840 and UniProtKB:P62136	9068941	PMID:17318175	IntAct	PMID:17318175
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P01106 more ...	9068941	PMID:19131971	IntAct	PMID:19131971
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O14641	9068941	PMID:21245303	IntAct	PMID:21245303
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P39687 and UniProtKB:Q14194	9068941	PMID:16169070	IntAct	PMID:16169070
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P25054 more ...	9068941	PMID:17510365	IntAct	PMID:17510365
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P70331-2 and UniProtKB:Q9P1T7	9068941	PMID:12192039	UniProt	PMID:12192039
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P25054	9068941	PMID:10811618	IntAct	PMID:10811618
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q9H7D7	9068941	PMID:27098453	IntAct	PMID:27098453
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:G2XKQ0 more ...	9068941	PMID:26871637	IntAct	PMID:26871637
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49674 and UniProtKB:P49841	9068941	PMID:21988832	IntAct	PMID:21988832
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P35222 more ...	9068941	PMID:24976009	IntAct	PMID:24976009
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:G1T8E2 and UniProtKB:P49841	9068941	PMID:10481074	IntAct	PMID:10481074
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49407 and UniProtKB:P49841	9068941	PMID:19202075	IntAct	PMID:19202075
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q5JTC6	9068941	PMID:17510365	ParkinsonsUK-UCL	PMID:17510365
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P35222	9068941	PMID:19166851	IntAct	PMID:19166851
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P14923 more ...	9068941	PMID:26496610	IntAct	PMID:26496610
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P25054 more ...	9068941	PMID:9601641	UniProt	PMID:9601641
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P25054 more ...	9068941	PMID:22682247	IntAct	PMID:22682247
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O15105 more ...	9068941	PMID:16601693	IntAct	PMID:16601693
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P35222 and UniProtKB:P49841	9068941	PMID:17318191 and PMID:21242974	IntAct	PMID:17318191 and PMID:21242974
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O14641 more ...	9068941	PMID:22773187	IntAct	PMID:22773187
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P35222 more ...	9068941	PMID:28829046	UniProt	PMID:28829046
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49841	9068941	PMID:11738041 more ...	IntAct	PMID:11738041 more ...
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P62137 and UniProtKB:P98078	9068941	PMID:19581931	IntAct	PMID:19581931
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O35182 more ...	9068941	PMID:16601693	IntAct	PMID:16601693
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P98078 and UniProtKB:Q61062	9068941	PMID:12805222	IntAct	PMID:12805222
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q9H2K2	9068941	PMID:22153077	IntAct	PMID:22153077
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O14640	9068941	PMID:10330181	IntAct	PMID:10330181 and REF_RGD_ID:4108508
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49840	9068941	PMID:33961781	IntAct	PMID:33961781
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O14640	9068941	PMID:11113207	BHF-UCL	PMID:11113207 and REF_RGD_ID:68802
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q03135	9068941	PMID:16890161	IntAct	PMID:16890161 and REF_RGD_ID:8554078
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q9Y4X0	9068941	PMID:21304492	IntAct	PMID:21304492 and REF_RGD_ID:8554596
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P70039	9068941	PMID:18786926	IntAct	PMID:18786926
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q5VWQ8-2	9068941	PMID:20080667	IntAct	PMID:20080667
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q92997	9068941	PMID:10330181	BHF-UCL	PMID:10330181 and REF_RGD_ID:4108508
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O75581	9068941	PMID:16890161	IntAct	PMID:16890161 and REF_RGD_ID:8554078
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q14134	9068941	PMID:19249679	IntAct	PMID:19249679
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49841	9068941	PMID:16890161	BHF-UCL	PMID:16890161 and REF_RGD_ID:8554078
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q02248	9068941	PMID:16293619	IntAct	PMID:16293619
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:D4ADV8	9068941	PMID:10330181	BHF-UCL	PMID:10330181 and REF_RGD_ID:4108508
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49674	9068941	PMID:11425858	IntAct	PMID:11425858 and REF_RGD_ID:8553771
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P35813	9068941	PMID:10644691	IntAct	PMID:10644691
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O75581	9068941	PMID:21304492	IntAct	PMID:21304492 and REF_RGD_ID:8554596
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q7Z699	9068941	PMID:32814053	IntAct	PMID:32814053
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O75581	9068941	PMID:23892894	IntAct	PMID:23892894
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P04637	9068941	PMID:21057547	IntAct	PMID:21057547
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q96EY1	9068941	PMID:17588722	UniProt	PMID:17588722
AXIN1	Green Monkey	protein binding		ISO	Magi2 (Rattus norvegicus)	9068941		RGD	PMID:15228590 and REF_RGD_ID:1304344
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P23258	9068941	PMID:19390532	IntAct	PMID:19390532
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q15583	9068941	PMID:25873176	IntAct	PMID:25873176
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:D3ZHV2	9068941	PMID:16815997	UniProt	PMID:16815997 and REF_RGD_ID:8553932
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O14640	9068941	PMID:11425858	IntAct	PMID:11425858 and REF_RGD_ID:8553771
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:P49840 and UniProtKB:P49841	9068941	PMID:23602568 and PMID:35271311	IntAct	PMID:23602568 and PMID:35271311
AXIN1	Green Monkey	protein binding	enables	ISO	UniProtKB:O75581	9068941	PMID:12897152 and PMID:19107203	IntAct	PMID:12897152 and PMID:19107203
AXIN1	Green Monkey	protein domain specific binding		ISO	Senp2 (Rattus norvegicus)	9068941		RGD	PMID:10944533 and REF_RGD_ID:1299408
AXIN1	Green Monkey	protein domain specific binding	enables	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein homodimerization activity	enables	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein kinase binding	enables	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	protein kinase binding	enables	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein serine/threonine kinase activator activity	enables	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	protein serine/threonine kinase binding	enables	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	R-SMAD binding	enables	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	signaling adaptor activity	enables	IEA	UniProtKB:O35625 and ensembl:ENSMUSP00000073974	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	signaling receptor binding	enables	ISO	UniProtKB:O75581	9068941	PMID:16890161	BHF-UCL	PMID:16890161 and REF_RGD_ID:8554078
AXIN1	Green Monkey	SMAD binding	enables	IEA	UniProtKB:O15169 and ensembl:ENSP00000262320	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	ubiquitin protein ligase binding	enables	IEA	PANTHER:PTN000090609	150520179		TreeGrafter	GO_REF:0000118
AXIN1	Green Monkey	ubiquitin protein ligase binding	enables	IEA	UniProtKB:O15169 more ...	150520179		Ensembl	GO_REF:0000107
AXIN1	Green Monkey	ubiquitin-like ligase-substrate adaptor activity	enables	IEA	UniProtKB:O15169 more ...	150520179		Ensembl	GO_REF:0000107

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	altered Wnt signaling, canonical pathway		ISO	AXIN1 (Homo sapiens)	9068941		RGD	PMID:18432252 and REF_RGD_ID:2293188
AXIN1	Green Monkey	colorectal cancer pathway		ISO	AXIN1 (Homo sapiens)	9068941		RGD	PMID:18432252 and REF_RGD_ID:2293188
AXIN1	Green Monkey	Wnt signaling, canonical pathway		ISO	AXIN1 (Homo sapiens)	9068941		RGD	PMID:18432252 and REF_RGD_ID:2293188

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
AXIN1	Green Monkey	N-cadherin signaling pathway		ISO	AXIN1 (Homo sapiens)	9068941		PID	PID:200209
AXIN1	Green Monkey	transforming growth factor-beta Smad dependent signaling pathway		ISO	AXIN1 (Homo sapiens)	9068941		PID	PID:200227
AXIN1	Green Monkey	Wnt signaling, canonical pathway		ISO	AXIN1 (Homo sapiens)	9068941		PID	PID:200077

PMID:30032202

AXIN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	233,520 - 295,134 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	234,060 - 290,575 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	30,878,427 - 30,943,289 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

AXIN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	287,440 - 352,723 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	287,440 - 352,723 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	337,440 - 402,723 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	277,441 - 342,465 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	277,440 - 342,465	NCBI
Celera	16	537,339 - 602,420 (-)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	255,743 - 344,360 (-)	NCBI		HuRef
CHM1_1	16	337,402 - 402,637 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	282,313 - 347,596 (-)	NCBI		T2T-CHM13v2.0

Axin1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	26,350,294 - 26,414,784 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	26,357,662 - 26,414,785 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	26,131,217 - 26,195,811 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	26,138,688 - 26,195,811 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	26,275,631 - 26,332,756 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	25,866,334 - 25,923,411 (+)	NCBI		MGSCv36	mm8
Celera	17	26,676,271 - 26,729,569 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	13.07	NCBI

Axin1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	15,667,894 - 15,720,092 (+)	NCBI		GRCr8
mRatBN7.2	10	15,163,477 - 15,215,615 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	15,163,684 - 15,215,615 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	19,903,082 - 19,955,387 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	19,391,961 - 19,444,266 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	14,891,384 - 14,943,546 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_5.0	10	15,324,330 - 15,376,252 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	15,409,373 - 15,462,726 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	15,410,421 - 15,463,774 (+)	NCBI
Celera	10	14,831,660 - 14,883,421 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

Axin1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	16,843,152 - 16,898,430 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	16,845,728 - 16,898,301 (+)	NCBI	ChiLan1.0	ChiLan1.0

AXIN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	506,910 - 581,764 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	4,299,164 - 4,372,528 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	16	278,239 - 337,891 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	278,239 - 337,891 (-)	Ensembl	panpan1.1		panPan2

AXIN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	40,155,797 - 40,218,330 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	40,158,244 - 40,218,343 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	41,419,076 - 41,481,969 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	40,497,801 - 40,560,709 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	40,500,504 - 40,560,706 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	40,186,114 - 40,248,973 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	40,146,325 - 40,210,047 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	40,625,599 - 40,688,493 (+)	NCBI		UU_Cfam_GSD_1.0

Axin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	112,502,114 - 112,535,977 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	599,919 - 633,873 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	599,963 - 633,837 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AXIN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	41,337,071 - 41,393,997 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	41,344,908 - 41,393,999 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	41,033,961 - 41,085,857 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Axin1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	1,139,165 - 1,195,230 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624913	1,139,165 - 1,195,477 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in AXIN1
1775 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20


RefSeq Transcripts	XM_007979643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007979653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007979658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037990080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037990081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037990082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000010939 ⟹ ENSCSAP00000009022

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	234,060 - 290,575 (-)	Ensembl

RefSeq Acc Id:

XM_037990080 ⟹ XP_037846008

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666068	30,883,438 - 30,943,289 (+)	NCBI

RefSeq Acc Id:

XM_037990081 ⟹ XP_037846009

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666068	30,878,427 - 30,943,289 (+)	NCBI

RefSeq Acc Id:

XM_037990082 ⟹ XP_037846010

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666068	30,878,436 - 30,943,288 (+)	NCBI


Protein RefSeqs	XP_037846008	(Get FASTA)	NCBI Sequence Viewer
	XP_037846009	(Get FASTA)	NCBI Sequence Viewer
	XP_037846010	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000009022.1

Ensembl Acc Id:

ENSCSAP00000009022 ⟸ ENSCSAT00000010939

RefSeq Acc Id:	XP_037846009 ⟸ XM_037990081
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RK83 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037846010 ⟸ XM_037990082
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_037846008 ⟸ XM_037990080
- Peptide Label:	isoform X1

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000012923	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000010939.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.167.10	UniProtKB/TrEMBL
	1.10.196.10	UniProtKB/TrEMBL
	2.40.240.130	UniProtKB/TrEMBL
InterPro	Axin-like	UniProtKB/TrEMBL
	Axin_b-cat-bd	UniProtKB/TrEMBL
	Axin_TNKS-bd	UniProtKB/TrEMBL
	DIX	UniProtKB/TrEMBL
	DIX_dom_sf	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
	RGS_sf	UniProtKB/TrEMBL
	RGS_subdom1/3	UniProtKB/TrEMBL
	RGS_subdomain_2	UniProtKB/TrEMBL
	Ubiquitin-like_domsf	UniProtKB/TrEMBL
NCBI Gene	AXIN1	ENTREZGENE
PANTHER	PTHR46102	UniProtKB/TrEMBL
	PTHR46102:SF3	UniProtKB/TrEMBL
Pfam	AXIN1_TNKS_BD	UniProtKB/TrEMBL
	Axin_b-cat_bind	UniProtKB/TrEMBL
	DIX	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
PRINTS	RGSPROTEIN	UniProtKB/TrEMBL
PROSITE	DIX	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
SMART	DAX	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48097	UniProtKB/TrEMBL
	SSF54236	UniProtKB/TrEMBL
UniProt	A0A0D9RK83	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)