Axin1 (axin 1) - Rat Genome Database

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Gene: Axin1 (axin 1) Ictidomys tridecemlineatus
Analyze
Symbol: Axin1
Name: axin 1
RGD ID: 12647489
Description: ENCODES a protein that exhibits armadillo repeat domain binding (ortholog); beta-catenin binding (ortholog); enzyme binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); adult walking behavior (ortholog); axial mesoderm development (ortholog); PARTICIPATES IN altered Wnt signaling, canonical pathway; colorectal cancer pathway; N-cadherin signaling pathway; ASSOCIATED WITH Caudal Duplication Anomaly (ortholog); hepatocellular carcinoma (ortholog); FOUND IN beta-catenin destruction complex (ortholog); cell cortex (ortholog); cell periphery (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: axin 1, transcript variant X1; axin 1, transcript variant X3; axin 1, transcript variant X4; axin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,502,114 - 112,535,977 (+)NCBI
SpeTri2.0NW_004936501599,963 - 633,837 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase activity  (ISO)
adult walking behavior  (ISO)
axial mesoderm development  (ISO)
axial mesoderm formation  (ISO)
canonical Wnt signaling pathway  (ISO)
cellular protein-containing complex assembly  (ISO)
cytoplasmic microtubule organization  (ISO)
dorsal/ventral axis specification  (ISO)
dorsal/ventral pattern formation  (ISO)
embryonic skeletal joint morphogenesis  (ISO)
erythrocyte homeostasis  (ISO)
genetic imprinting  (ISO)
head development  (ISO)
hemoglobin metabolic process  (ISO)
in utero embryonic development  (ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
negative regulation of fat cell differentiation  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of protein metabolic process  (ISO)
negative regulation of transcription elongation from RNA polymerase II promoter  (ISO)
negative regulation of Wnt signaling pathway  (ISO)
nervous system process  (ISO)
nucleocytoplasmic transport  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of JUN kinase activity  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of peptidyl-threonine phosphorylation  (ISO)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (ISO)
positive regulation of protein catabolic process  (ISO)
positive regulation of protein kinase activity  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein ubiquitination  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of transforming growth factor beta receptor signaling pathway  (ISO)
positive regulation of ubiquitin-dependent protein catabolic process  (ISO)
positive regulation of ubiquitin-protein transferase activity  (ISO)
post-anal tail morphogenesis  (ISO)
protein catabolic process  (ISO)
protein polyubiquitination  (ISO)
regulation of canonical Wnt signaling pathway  (ISO)
regulation of protein phosphorylation  (ISO)
sensory perception of sound  (ISO)
Wnt signaling pathway  (ISO)

References

Genomics

Comparative Map Data
Axin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,502,114 - 112,535,977 (+)NCBI
SpeTri2.0NW_004936501599,963 - 633,837 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AXIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl16287,440 - 352,723 (-)EnsemblGRCh38hg38GRCh38
GRCh3816287,440 - 355,226 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716337,440 - 402,723 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616277,441 - 342,465 (-)NCBINCBI36hg18NCBI36
Build 3416277,440 - 342,465NCBI
Celera16537,339 - 602,420 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef16255,743 - 344,360 (-)NCBIHuRef
CHM1_116337,402 - 402,637 (-)NCBICHM1_1
Axin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,350,208 - 26,414,785 (+)NCBIGRCm39mm39
GRCm39 Ensembl1726,357,662 - 26,414,785 (+)Ensembl
GRCm381726,131,217 - 26,195,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,138,688 - 26,195,811 (+)EnsemblGRCm38mm10GRCm38
MGSCv371726,275,631 - 26,332,756 (+)NCBIGRCm37mm9NCBIm37
MGSCv361725,866,334 - 25,923,411 (+)NCBImm8
Celera1726,676,271 - 26,729,569 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.07NCBI
Axin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21015,163,684 - 15,215,615 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1015,163,684 - 15,215,615 (+)Ensembl
Rnor_5.01015,324,330 - 15,376,252 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,409,373 - 15,462,726 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,410,421 - 15,463,774 (+)NCBI
Celera1014,831,660 - 14,883,421 (+)NCBICelera
Cytogenetic Map10q12NCBI
Axin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,843,152 - 16,898,430 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,845,728 - 16,898,301 (+)NCBIChiLan1.0ChiLan1.0
AXIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.116278,239 - 337,891 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16278,239 - 337,891 (-)Ensemblpanpan1.1panPan2
AXIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,155,797 - 40,218,330 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,158,244 - 40,218,343 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,419,076 - 41,481,969 (+)NCBI
ROS_Cfam_1.0640,497,801 - 40,560,709 (+)NCBI
UMICH_Zoey_3.1640,186,114 - 40,248,973 (+)NCBI
UNSW_CanFamBas_1.0640,146,325 - 40,210,047 (+)NCBI
UU_Cfam_GSD_1.0640,625,599 - 40,688,493 (+)NCBI
AXIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,337,071 - 41,393,997 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,344,908 - 41,393,999 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,033,961 - 41,085,857 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AXIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15233,520 - 295,134 (-)NCBI
ChlSab1.1 Ensembl5234,060 - 290,575 (-)Ensembl
Vero_WHO_p1.0NW_02366606830,878,427 - 30,943,289 (+)NCBI
Axin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249131,139,165 - 1,195,477 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005323664   ⟹   XP_005323721
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344112,502,114 - 112,535,977 (+)NCBI
SpeTri2.0NW_004936501599,963 - 633,837 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005323665   ⟹   XP_005323722
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344112,502,152 - 112,535,977 (+)NCBI
SpeTri2.0NW_004936501599,963 - 633,837 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021725396   ⟹   XP_021581071
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344112,502,152 - 112,533,168 (+)NCBI
SpeTri2.0NW_004936501599,973 - 631,028 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002483763
RefSeq Status:
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936501599,973 - 631,095 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005323721   ⟸   XM_005323664
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005323722   ⟸   XM_005323665
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021581071   ⟸   XM_021725396
- Peptide Label: isoform X3
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000012303 ENTREZGENE
Ensembl Protein ENSSTOP00000011023 ENTREZGENE
  ENSSTOP00000025498 ENTREZGENE
NCBI Gene Axin1 ENTREZGENE