ADAMTS17 (ADAM metallopeptidase with thrombospondin type 1 motif 17) - Rat Genome Database

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Gene: ADAMTS17 (ADAM metallopeptidase with thrombospondin type 1 motif 17) Chlorocebus sabaeus
Analyze
Symbol: ADAMTS17
Name: ADAM metallopeptidase with thrombospondin type 1 motif 17
RGD ID: 18344129
Description: ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN extracellular matrix organization (inferred); proteolysis (inferred); ASSOCIATED WITH anterior segment dysgenesis (ortholog); chromosome 15q26-qter deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A disintegrin and metalloproteinase with thrombospondin motifs 17
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12918,484,341 - 18,842,210 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2918,481,449 - 18,841,568 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605927,706,636 - 28,072,381 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADAMTS17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12918,484,341 - 18,842,210 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2918,481,449 - 18,841,568 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605927,706,636 - 28,072,381 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ADAMTS17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381599,971,437 - 100,341,975 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1599,971,437 - 100,342,005 (-)EnsemblGRCh38hg38GRCh38
GRCh3715100,511,642 - 100,882,180 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361598,329,166 - 98,699,706 (-)NCBINCBI36Build 36hg18NCBI36
Build 341598,331,992 - 98,699,650NCBI
Celera1576,928,247 - 77,297,865 (-)NCBICelera
Cytogenetic Map15q26.3NCBI
HuRef1576,635,097 - 77,005,861 (-)NCBIHuRef
CHM1_115100,352,643 - 100,723,097 (-)NCBICHM1_1
T2T-CHM13v2.01597,727,466 - 98,099,930 (-)NCBIT2T-CHM13v2.0
Adamts17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39766,487,387 - 66,802,373 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl766,489,483 - 66,802,919 (+)EnsemblGRCm39 Ensembl
GRCm38766,839,699 - 67,153,171 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl766,839,735 - 67,153,171 (+)EnsemblGRCm38mm10GRCm38
MGSCv37773,984,621 - 74,297,511 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36766,718,685 - 66,907,082 (+)NCBIMGSCv36mm8
Celera764,293,133 - 64,614,309 (+)NCBICelera
Cytogenetic Map7CNCBI
cM Map736.26NCBI
Adamts17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81129,856,062 - 130,178,430 (+)NCBIGRCr8
mRatBN7.21120,445,800 - 120,768,204 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1120,445,749 - 120,768,202 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01127,802,872 - 128,126,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,802,978 - 128,124,171 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01128,877,889 - 129,194,795 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41121,324,404 - 121,491,594 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11121,414,177 - 121,580,676 (+)NCBI
Celera1112,647,804 - 112,970,110 (+)NCBICelera
Cytogenetic Map1q22NCBI
Adamts17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541627,130,559 - 27,434,747 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541627,128,066 - 27,434,826 (-)NCBIChiLan1.0ChiLan1.0
ADAMTS17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21689,565,810 - 89,941,882 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11593,260,946 - 93,634,190 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01578,703,728 - 79,076,861 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11597,997,843 - 98,366,959 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1597,999,448 - 98,366,893 (-)Ensemblpanpan1.1panPan2
ADAMTS17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1340,613,902 - 40,939,616 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl340,613,759 - 40,939,615 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha343,305,552 - 43,637,568 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0341,014,731 - 41,340,884 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl341,014,684 - 41,340,881 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1340,547,918 - 40,873,550 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0340,778,980 - 41,104,683 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0340,986,070 - 41,324,350 (+)NCBIUU_Cfam_GSD_1.0
Adamts17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640142,599,335 - 142,946,240 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364833,388,342 - 3,732,639 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364833,388,269 - 3,735,169 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1138,619,706 - 139,015,473 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11138,619,701 - 139,015,681 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21154,833,394 - 154,998,125 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Adamts17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247684,309,035 - 4,629,289 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247684,308,993 - 4,630,499 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 3 3
Low 36 15 57
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014972   ⟹   ENSCSAP00000012928
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2918,481,449 - 18,841,568 (-)Ensembl
RefSeq Acc Id: XM_007990567   ⟹   XP_007988758
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12918,484,341 - 18,842,210 (-)NCBI
Vero_WHO_p1.0NW_02366605927,706,636 - 28,072,381 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007988758 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012928.1
Reference Protein Sequences
RefSeq Acc Id: XP_007988758   ⟸   XM_007990567
- UniProtKB: A0A0D9RWD9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012928   ⟸   ENSCSAT00000014972


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016882 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014972.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
  3.40.1620.60 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_Cys-rich UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  ADAMTS/ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene ADAMTS17 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 17 UniProtKB/TrEMBL
  ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
Pfam ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_CR_3 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS ADAMTSFAMILY UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A0D9RWD9 ENTREZGENE, UniProtKB/TrEMBL