MARCO (macrophage receptor with collagenous structure) - Rat Genome Database

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Gene: MARCO (macrophage receptor with collagenous structure) Chlorocebus sabaeus
Analyze
Symbol: MARCO
Name: macrophage receptor with collagenous structure
RGD ID: 18552290
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); cargo receptor activity (ortholog); G protein-coupled receptor binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); amyloid-beta clearance (ortholog); apoptotic cell clearance (ortholog); ASSOCIATED WITH Bacterial Lung Diseases (ortholog); Clostridium Infections (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: macrophage receptor MARCO
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11011,329,036 - 11,389,428 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1011,329,026 - 11,388,999 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606111,291,422 - 11,352,136 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
MARCO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11011,329,036 - 11,389,428 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1011,329,026 - 11,388,999 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606111,291,422 - 11,352,136 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MARCO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382118,942,194 - 118,994,660 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2118,942,194 - 118,994,660 (+)EnsemblGRCh38hg38GRCh38
GRCh372119,699,770 - 119,752,236 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362119,416,215 - 119,468,706 (+)NCBINCBI36Build 36hg18NCBI36
Build 342119,415,974 - 119,468,467NCBI
Celera2113,024,535 - 113,078,253 (+)NCBICelera
Cytogenetic Map2q14.2NCBI
HuRef2112,024,650 - 112,076,879 (+)NCBIHuRef
CHM1_12119,703,356 - 119,755,847 (+)NCBICHM1_1
T2T-CHM13v2.02119,375,479 - 119,427,929 (+)NCBIT2T-CHM13v2.0
Marco
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,402,267 - 120,432,753 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,402,267 - 120,432,753 (-)EnsemblGRCm39 Ensembl
GRCm381120,474,538 - 120,505,024 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,474,538 - 120,505,024 (-)EnsemblGRCm38mm10GRCm38
MGSCv371122,371,115 - 122,401,661 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361122,302,084 - 122,332,630 (-)NCBIMGSCv36mm8
Celera1123,137,568 - 123,168,212 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.71NCBI
Marco
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81334,169,011 - 34,210,340 (-)NCBIGRCr8
mRatBN7.21331,616,278 - 31,648,521 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1331,616,278 - 31,648,521 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1334,183,224 - 34,215,428 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01335,471,075 - 35,503,279 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01332,745,488 - 32,777,692 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01685,115,199 - 85,147,683 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1685,115,201 - 85,135,859 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01684,555,641 - 84,587,281 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1331,497,203 - 31,529,354 (-)NCBICelera
Cytogenetic Map13q11NCBI
Marco
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545910,698,294 - 10,739,131 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545910,700,645 - 10,739,222 (-)NCBIChiLan1.0ChiLan1.0
MARCO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21320,962,321 - 21,006,160 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B20,977,294 - 21,021,133 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B5,896,433 - 5,940,284 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B119,475,704 - 119,519,918 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B119,475,677 - 119,520,385 (+)Ensemblpanpan1.1panPan2
MARCO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11930,996,209 - 31,034,520 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1930,996,347 - 31,034,487 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1931,260,569 - 31,305,455 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01932,381,105 - 32,426,221 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1932,381,113 - 32,419,679 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11931,067,312 - 31,112,187 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01931,233,786 - 31,278,688 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01932,420,649 - 32,465,527 (-)NCBIUU_Cfam_GSD_1.0
Marco
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530390,251,204 - 90,294,071 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493646951,323,746 - 51,366,551 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARCO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1524,503,108 - 24,541,283 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11524,502,935 - 24,541,286 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21528,139,421 - 28,177,787 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Marco
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473226,203,219 - 26,236,057 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473226,203,345 - 26,236,001 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
40 22 17 31 31 26 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007964737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000014643   ⟹   ENSCSAP00000012609
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1011,329,026 - 11,388,999 (-)Ensembl
RefSeq Acc Id: XM_007964737   ⟹   XP_007962928
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11011,329,036 - 11,389,428 (-)NCBI
Vero_WHO_p1.0NW_02366606111,291,422 - 11,352,136 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007962928 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012609.1
RefSeq Acc Id: XP_007962928   ⟸   XM_007964737
- UniProtKB: A0A0D9RVH0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000012609   ⟸   ENSCSAT00000014643


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016551 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014643.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.250.10 UniProtKB/TrEMBL
InterPro Collagen UniProtKB/TrEMBL
  Collagen_superfamily UniProtKB/TrEMBL
  SRCR UniProtKB/TrEMBL
  SRCR-like_dom UniProtKB/TrEMBL
  SRCR-like_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103216933 UniProtKB/TrEMBL
NCBI Gene MARCO ENTREZGENE
PANTHER COLLAGEN ALPHA UniProtKB/TrEMBL
  MACROPHAGE RECEPTOR MARCO UniProtKB/TrEMBL
Pfam Collagen UniProtKB/TrEMBL
  SRCR UniProtKB/TrEMBL
PRINTS SPERACTRCPTR UniProtKB/TrEMBL
PROSITE SRCR_1 UniProtKB/TrEMBL
  SRCR_2 UniProtKB/TrEMBL
SMART SM00202 UniProtKB/TrEMBL
Superfamily-SCOP SSF56487 UniProtKB/TrEMBL
UniProt A0A0D9RVH0 ENTREZGENE, UniProtKB/TrEMBL