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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Indeno[1,2,3-cd]pyrene
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Accession:CHEBI:82335 term browser browse the term
Definition:A pyrene that has formula C22H12.
Synonyms:related_synonym: Formula=C22H12;   InChI=1S/C22H12/c1-2-7-17-16(6-1)18-11-10-14-9-8-13-4-3-5-15-12-19(17)22(18)21(14)20(13)15/h1-12H;   InChIKey=SXQBHARYMNFBPS-UHFFFAOYSA-N;   SMILES=c1ccc2c(c1)c1ccc3ccc4cccc5cc2c1c3c45
 xref: CAS:193-39-5;   KEGG:C19251
 xref_mesh: MESH:C041508


show annotations for term's descendants           Sort by:
Indeno[1,2,3-cd]pyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ABCC5 mRNA CTD PMID:32251684 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ACSM3 mRNA CTD PMID:26377693 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADAMTS15 mRNA CTD PMID:26377693 NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249 		JBrowse link
G Adig adipogenin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADIG mRNA CTD PMID:26377693 NCBI chr 3:147,155,079...147,160,412
Ensembl chr 3:147,154,097...147,160,490
Ensembl chr 3:147,154,097...147,160,490 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADIPOQ mRNA CTD PMID:26377693 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADORA1 mRNA CTD PMID:32251684 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression
increases activity		 ISO
EXP		 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [indeno(1,2,3-cd)pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene] promotes the reaction [pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with pyrene] promotes the reaction [fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [chrysene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(k)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(j)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; [Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benz(a)anthracene results in increased activity of AHR protein]; [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein] which results in increased abundance of Kynurenine; AHR promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of IKZF1 protein]; AHR promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MYC protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]; indeno(1,2,3-cd)pyrene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]
AHR protein affects the reaction [[indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IRF4 mRNA]; AHR protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of BCL6 mRNA]]; AHR protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL21 mRNA]]
indeno(1,2,3-cd)pyrene results in increased expression of AHR mRNA; indeno(1,2,3-cd)pyrene results in increased expression of AHR protein
indeno(1,2,3-cd)pyrene binds to and results in increased activity of AHR protein		 CTD PMID:11525907 PMID:12371477 PMID:12850102 PMID:17665671 PMID:21781905 More... NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AHRR mRNA CTD PMID:32251684 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AKR1C1 mRNA CTD PMID:17253728 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ALDH1A2 mRNA CTD PMID:26377693 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ALDH1A3 mRNA CTD PMID:32251684 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ALDH3A1 mRNA CTD PMID:32251684 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Amer2 APC membrane recruitment protein 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AMER2 mRNA CTD PMID:32251684 NCBI chr15:34,525,352...34,535,660
Ensembl chr15:34,524,542...34,528,455 		JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ANGPTL4 mRNA CTD PMID:26377693 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Areg amphiregulin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of AREG mRNA CTD PMID:26377693 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ARL4D mRNA CTD PMID:26377693 NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836 		JBrowse link
G Asgr2 asialoglycoprotein receptor 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ASGR2 mRNA CTD PMID:26377693 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ATOH8 mRNA CTD PMID:32251684 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BAIAP2L1 mRNA CTD PMID:26377693 NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor multiple interactions ISO [indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of BATF mRNA CTD PMID:36975775 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Bche butyrylcholinesterase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BCHE mRNA CTD PMID:26377693 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in decreased expression of BCL6 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of BCL6 mRNA]]; AHR protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of BCL6 mRNA]]; indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of BCL6 mRNA]		 CTD PMID:26377693 PMID:36975775 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BMAL1 mRNA CTD PMID:26377693 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bnc1 basonuclin zinc finger protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BNC1 mRNA CTD PMID:26377693 NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333 		JBrowse link
G Bpifa1 BPI fold containing family A, member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BPIFA1 mRNA CTD PMID:26377693 NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552 		JBrowse link
G C2 complement C2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of C2 mRNA CTD PMID:26377693 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cacybp calcyclin binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CACYBP mRNA CTD PMID:26377693 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177 		JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CADM1 mRNA CTD PMID:21635667 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Car14 carbonic anhydrase 14 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CAR14 mRNA CTD PMID:26377693 NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693 		JBrowse link
G Car3 carbonic anhydrase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CAR3 mRNA CTD PMID:26377693 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCDC80 mRNA CTD PMID:26377693 NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137 		JBrowse link
G Ccdc85a coiled-coil domain containing 85A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCDC85A mRNA CTD PMID:26377693 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCNA2 mRNA CTD PMID:32251684 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in increased expression of CCND1 mRNA
1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]		 CTD PMID:35687267 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccng2 cyclin G2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CCNG2 mRNA CTD PMID:32251684 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Ccnjl cyclin J-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCNJL mRNA CTD PMID:26377693 NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CEBPB mRNA CTD PMID:32251684 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CEBPD mRNA CTD PMID:26377693 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CELSR2 mRNA CTD PMID:21635667 PMID:32251684 NCBI chr 2:196,029,206...196,053,848
Ensembl chr 2:196,029,434...196,053,845 		JBrowse link
G Cenpa centromere protein A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CENPA mRNA CTD PMID:32251684 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cfd complement factor D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CFD mRNA CTD PMID:26377693 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CHORDC1 mRNA CTD PMID:26377693 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CIDEA mRNA CTD PMID:26377693 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CKMT2 mRNA CTD PMID:26377693 NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430 		JBrowse link
G Cldn17 claudin 17 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLDN17 mRNA CTD PMID:21635667 NCBI chr11:27,827,454...27,828,630
Ensembl chr11:27,827,454...27,828,630 		JBrowse link
G Clec10a C-type lectin domain containing 10A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLEC10A mRNA CTD PMID:26377693 NCBI chr10:54,876,244...54,880,439
Ensembl chr10:54,876,260...54,880,435 		JBrowse link
G Clec9a C-type lectin domain containing 9A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLEC9A mRNA CTD PMID:26377693 NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352 		JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLIC4 mRNA CTD PMID:26377693 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452 		JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COL2A1 mRNA CTD PMID:21635667 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col4a6 collagen type IV alpha 6 chain decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COL4A6 mRNA CTD PMID:21635667 NCBI chr  X:104,766,463...105,117,499
Ensembl chr  X:104,766,957...105,117,500 		JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COX7A1 mRNA CTD PMID:26377693 NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CREB1 mRNA CTD PMID:32251684 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CSRP3 mRNA CTD PMID:26377693 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Ctsb cathepsin B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CTSB mRNA CTD PMID:32251684 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsd cathepsin D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CTSD mRNA CTD PMID:32251684 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CXCL12 mRNA CTD PMID:32251684 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity		 ISO
EXP		 Dexamethasone inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 protein]; indeno(1,2,3-cd)pyrene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]
[indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of CYP1A1 mRNA
indeno(1,2,3-cd)pyrene results in increased activity of CYP1A1 protein
indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 protein		 CTD PMID:10190573 PMID:17253728 PMID:19463884 PMID:21781905 PMID:26377693 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CYP1A2 mRNA CTD PMID:17253728 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein
1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein]		 CTD PMID:17253728 PMID:27196671 PMID:35687267 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of DDIT4 mRNA CTD PMID:32251684 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DGAT2 mRNA CTD PMID:26377693 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dnaaf10 dynein axonemal assembly factor 10 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DNAAF10 mRNA CTD PMID:26377693 NCBI chr14:91,618,649...91,639,828
Ensembl chr14:91,636,157...91,639,831 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DNAJA1 mRNA CTD PMID:26377693 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dpt dermatopontin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DPT mRNA CTD PMID:26377693 NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DVL3 mRNA CTD PMID:26377693 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DYNLL1 mRNA CTD PMID:26377693 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in increased expression of E2F1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein
1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein]		 CTD PMID:35687267 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of EFEMP1 mRNA CTD PMID:26377693 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ELOVL6 mRNA CTD PMID:26377693 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Ephb6 Eph receptor B6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of EPHB6 mRNA CTD PMID:26377693 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ERBB2 mRNA CTD PMID:21635667 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ERRFI1 mRNA CTD PMID:26377693 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO indeno(1,2,3-cd)pyrene binds to ESR1 protein CTD PMID:32251684 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA] CTD PMID:21635667 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions
increases expression		 ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein]
indeno(1,2,3-cd)pyrene results in increased expression of ETV6 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein		 CTD PMID:35687267 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992 		JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FABP4 mRNA CTD PMID:26377693 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fam181b family with sequence similarity 181, member B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FAM181B mRNA CTD PMID:26377693 NCBI chr 1:147,166,428...147,167,925
Ensembl chr 1:147,124,740...147,168,298
Ensembl chr 1:147,124,740...147,168,298 		JBrowse link
G Fibin fin bud initiation factor homolog decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FIBIN mRNA CTD PMID:26377693 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FOS mRNA CTD PMID:32251684 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Frem1 Fras1 related extracellular matrix 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FREM1 mRNA CTD PMID:21635667 NCBI chr 5:97,321,266...97,469,523
Ensembl chr 5:97,322,538...97,469,543 		JBrowse link
G Fsbp fibrinogen silencer binding protein increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of FSBP mRNA CTD PMID:32251684 NCBI chr 5:25,058,003...25,064,276
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GDPD2 mRNA CTD PMID:26377693 NCBI chr  X:65,826,273...65,835,361
Ensembl chr  X:65,826,574...65,835,361 		JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GFPT2 mRNA CTD PMID:26377693 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329 		JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of GJB2 mRNA CTD PMID:32251684 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Golph3l golgi phosphoprotein 3-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GOLPH3L mRNA CTD PMID:26377693 NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GPD1 mRNA CTD PMID:26377693 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529 		JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GPM6A mRNA CTD PMID:26377693 NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475 		JBrowse link
G Grifin galectin-related inter-fiber protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GRIFIN mRNA CTD PMID:26377693 NCBI chr12:14,080,170...14,082,892
Ensembl chr12:14,080,910...14,082,877 		JBrowse link
G Grp gastrin releasing peptide decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GRP mRNA CTD PMID:26377693 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Gxylt2 glucoside xylosyltransferase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GXYLT2 mRNA CTD PMID:26377693 NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454 		JBrowse link
G Gzma granzyme A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GZMA mRNA CTD PMID:26377693 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G Has1 hyaluronan synthase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HAS1 mRNA CTD PMID:26377693 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of HMOX1 mRNA CTD PMID:32251684 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hrc histidine rich calcium binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HRC mRNA CTD PMID:26377693 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSP90AA1 mRNA CTD PMID:26377693 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPA1A mRNA CTD PMID:26377693 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPA8 mRNA CTD PMID:26377693 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPD1 mRNA CTD PMID:26377693 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPH1 mRNA CTD PMID:26377693 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IDO1 protein CTD PMID:35687267 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IDO2 protein CTD PMID:35687267 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IER3 mRNA CTD PMID:22579512 PMID:32251684 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IGF1R mRNA CTD PMID:32251684 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IGFBP5 mRNA CTD PMID:26377693 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 increases expression
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in increased expression of IKZF1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of IKZF1 protein
AHR promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of IKZF1 protein]		 CTD PMID:35687267 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416 		JBrowse link
G Il21 interleukin 21 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL21 mRNA]]; AHR protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL21 mRNA]]; indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL21 mRNA]; MAF protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL21 mRNA]] CTD PMID:36975775 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO [indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IL4 mRNA; MAF protein affects the reaction [[indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IL4 mRNA] CTD PMID:36975775 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IQSEC1 mRNA CTD PMID:26377693 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IRF2BP2 mRNA CTD PMID:26377693 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642 		JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IRF4 mRNA]; [indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IRF4 mRNA; AHR protein affects the reaction [[indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IRF4 mRNA] CTD PMID:36975775 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Isx intestine-specific homeobox increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ISX protein CTD PMID:35687267 NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760 		JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA] CTD PMID:21635667 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itga6 integrin subunit alpha 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ITGA6 mRNA CTD PMID:26377693 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428 		JBrowse link
G Itgb6 integrin subunit beta 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ITGB6 mRNA CTD PMID:26377693 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of JCHAIN mRNA CTD PMID:26377693 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA] CTD PMID:21635667 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kdm1b lysine demethylase 1B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KDM1B mRNA CTD PMID:26377693 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800 		JBrowse link
G Kitlg KIT ligand decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KITL mRNA CTD PMID:26377693 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Klhl23 kelch-like family member 23 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PHOSPHO2-KLHL23 mRNA CTD PMID:32251684 NCBI chr 3:54,580,788...54,594,530
Ensembl chr 3:54,580,961...54,594,530 		JBrowse link
G Klk1 kallikrein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KLK1 mRNA CTD PMID:26377693 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754 		JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KNSTRN mRNA CTD PMID:26377693 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715 		JBrowse link
G Krt19 keratin 19 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KRT19 mRNA CTD PMID:32251684 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Lgals1 galectin 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of LGALS1 mRNA CTD PMID:22579512 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LONRF3 mRNA CTD PMID:26377693 NCBI chr  X:115,565,214...115,603,886
Ensembl chr  X:115,565,267...115,598,809 		JBrowse link
G Lpin2 lipin 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LPIN2 mRNA CTD PMID:26377693 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193 		JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LRRN4 mRNA CTD PMID:26377693 NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831 		JBrowse link
G Maf MAF bZIP transcription factor multiple interactions ISO indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of MAF mRNA]; MAF protein affects the reaction [[indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IL4 mRNA]; MAF protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL21 mRNA]] CTD PMID:36975775 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein
Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]		 CTD PMID:21635667 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mb myoglobin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MB mRNA CTD PMID:26377693 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of MDM2 mRNA CTD PMID:32251684 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mef2b myocyte enhancer factor 2B increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of MEF2B mRNA CTD PMID:32251684 NCBI chr16:19,253,008...19,269,514
Ensembl chr16:19,253,010...19,268,967 		JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MFAP2 mRNA CTD PMID:26377693 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259 		JBrowse link
G Mgat1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MGAT1 mRNA CTD PMID:26377693 NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in increased expression of MKI67 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein
1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein]		 CTD PMID:35687267 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA] CTD PMID:21635667 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MMP3 mRNA CTD PMID:26377693 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MNDA mRNA CTD PMID:26377693 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MRAP mRNA CTD PMID:26377693 NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024 		JBrowse link
G Msln mesothelin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MSLN mRNA CTD PMID:26377693 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MTARC1 mRNA CTD PMID:26377693 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796 		JBrowse link
G Muc16 mucin 16, cell surface associated decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MUC16 mRNA CTD PMID:26377693 NCBI chr 8:16,164,531...16,323,126 JBrowse link
G Mybpc3 myosin binding protein C3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYBPC3 mRNA CTD PMID:26377693 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MYC protein] CTD PMID:35687267 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myh6 myosin heavy chain 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYH6 mRNA CTD PMID:26377693 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myl1 myosin, light chain 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL1 mRNA CTD PMID:26377693 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261 		JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL4 mRNA CTD PMID:26377693 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363 		JBrowse link
G Myl7 myosin light chain 7 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL7 mRNA CTD PMID:26377693 NCBI chr14:80,780,684...80,783,259
Ensembl chr14:80,779,776...80,783,244 		JBrowse link
G Mylk myosin light chain kinase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYLK mRNA CTD PMID:21635667 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
G Nanog Nanog homeobox increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of NANOG mRNA CTD PMID:35687267 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NDC80 mRNA CTD PMID:22579512 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NEDD4 mRNA CTD PMID:26377693 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NFIL3 mRNA CTD PMID:26377693 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of NQO1 mRNA CTD PMID:17253728 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of OASL1 mRNA CTD PMID:26377693 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Otop1 otopetrin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of OTOP1 mRNA CTD PMID:26377693 NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497 		JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PAH mRNA CTD PMID:22579512 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pals2 protein associated with LIN7 2, MAGUK p55 family member decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PALS2 mRNA CTD PMID:26377693 NCBI chr 4:79,173,488...79,257,542
Ensembl chr 4:79,124,806...79,254,140 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO indeno(1,2,3-cd)pyrene results in increased cleavage of PARP1 protein CTD PMID:21132278 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PBX1 mRNA CTD PMID:26377693 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PCK1 mRNA CTD PMID:26377693 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pde5a phosphodiesterase 5A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDE5A mRNA CTD PMID:26377693 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDK4 mRNA CTD PMID:26377693 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pdzd2 PDZ domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDZD2 mRNA CTD PMID:26377693 NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:61,386,381...61,770,524 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PEBP1 mRNA CTD PMID:26377693 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
G Penk proenkephalin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PENK mRNA CTD PMID:26377693 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGAM2 mRNA CTD PMID:26377693 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940 		JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGAP2 mRNA CTD PMID:26377693 NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114 		JBrowse link
G Pgr progesterone receptor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGR mRNA CTD PMID:32251684 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Phf19 PHD finger protein 19 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PHF19 mRNA CTD PMID:32251684 NCBI chr 3:18,175,281...18,197,289
Ensembl chr 3:18,175,282...18,196,405 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PKIB mRNA CTD PMID:32251684 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Plin1 perilipin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PLIN1 mRNA CTD PMID:26377693 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828 		JBrowse link
G Plin4 perilipin 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PLIN4 mRNA CTD PMID:26377693 NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056 		JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of POLR1B mRNA CTD PMID:26377693 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379 		JBrowse link
G Popdc2 popeye domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of POPDC2 mRNA CTD PMID:26377693 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression
multiple interactions		 ISO indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein
1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein]; AHR promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein]		 CTD PMID:35687267 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PPP4R3B mRNA CTD PMID:26377693 NCBI chr14:102,917,043...102,965,210
Ensembl chr14:102,917,443...103,068,192 		JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RARA mRNA CTD PMID:32251684 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Reln reelin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RELN mRNA CTD PMID:21635667 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Ret ret proto-oncogene decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RET mRNA CTD PMID:32251684 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Retn resistin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RETN mRNA CTD PMID:26377693 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rhoc ras homolog family member C increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RHOC mRNA CTD PMID:22579512 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306 		JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RORA mRNA CTD PMID:26377693 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Rprml reprimo-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RPRML mRNA CTD PMID:26377693 NCBI chr10:88,560,248...88,561,252
Ensembl chr10:88,560,248...88,561,252 		JBrowse link
G Rps10l6 ribosomal protein S10-like 6 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RPS10-NUDT3 mRNA CTD PMID:32251684 NCBI chr15:18,308,287...18,309,139 JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RSRP1 mRNA CTD PMID:26377693 NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523 		JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions
increases expression		 ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein]
indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein		 CTD PMID:35687267 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RUNX2 mRNA CTD PMID:32251684 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sbsn suprabasin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SBSN mRNA CTD PMID:26377693 NCBI chr 1:85,978,970...86,006,034
Ensembl chr 1:86,001,567...86,006,034 		JBrowse link
G Sdcbp2 syndecan binding protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SDCBP2 mRNA CTD PMID:26377693 NCBI chr 3:140,060,746...140,098,063
Ensembl chr 3:140,070,540...140,098,057 		JBrowse link
G Sema3b semaphorin 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SEMA3B mRNA CTD PMID:32251684 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919 		JBrowse link
G Septin3 septin 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SEPTIN3 mRNA CTD PMID:26377693 NCBI chr 7:113,783,217...113,811,089
Ensembl chr 7:113,783,095...113,811,087 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SGK1 mRNA CTD PMID:32251684 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Shc3 SHC adaptor protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SHC3 mRNA CTD PMID:21635667 NCBI chr17:13,652,247...13,772,710
Ensembl chr17:13,651,202...13,772,710 		JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SIAH2 mRNA CTD PMID:32251684 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950 		JBrowse link
G Slc10a6 solute carrier family 10 member 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC10A6 mRNA CTD PMID:26377693 NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC1A5 mRNA CTD PMID:26377693 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC2A4 mRNA CTD PMID:26377693 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC2A5 mRNA CTD PMID:26377693 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106 		JBrowse link
G Slc5a12 solute carrier family 5 member 12 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC5A12 mRNA CTD PMID:26377693 NCBI chr 3:97,179,326...97,228,405
Ensembl chr 3:97,179,326...97,228,405 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC5A3 mRNA CTD PMID:26377693 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of SLC7A11 mRNA CTD PMID:32251684 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of SLC7A5 mRNA CTD PMID:32251684 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Sln sarcolipin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLN mRNA CTD PMID:26377693 NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SMPD3 mRNA CTD PMID:26377693 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA] CTD PMID:21635667 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snord123 small nucleolar RNA, C/D box 123 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SNORD123 mRNA CTD PMID:26377693 NCBI chr 2:83,306,918...83,306,987
Ensembl chr 2:83,306,918...83,306,987 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SOX17 mRNA CTD PMID:26377693 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox2 SRY-box transcription factor 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of SOX2 mRNA CTD PMID:35687267 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of STC2 mRNA CTD PMID:32251684 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of STIP1 mRNA CTD PMID:26377693 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SULF1 mRNA CTD PMID:26377693 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Syt1 synaptotagmin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SYT1 mRNA CTD PMID:26377693 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase multiple interactions
increases expression		 ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of TDO2 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of TDO2 protein] CTD PMID:35687267 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
G Tfap2c transcription factor AP-2 gamma decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFAP2C mRNA CTD PMID:32251684 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995 		JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFF1 mRNA CTD PMID:32251684 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tff3 trefoil factor 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFF3 mRNA CTD PMID:26377693 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054 		JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of THRSP mRNA CTD PMID:26377693 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
decreases expression		 ISO indeno(1,2,3-cd)pyrene results in increased expression of TIMP1 mRNA
indeno(1,2,3-cd)pyrene results in decreased expression of TIMP1 mRNA		 CTD PMID:22579512 PMID:26377693 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tln2 talin 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TLN2 mRNA CTD PMID:21635667 NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219 		JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEFF1 mRNA CTD PMID:32251684 NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493 		JBrowse link
G Tmem245 transmembrane protein 245 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEM245 mRNA CTD PMID:26377693 NCBI chr 5:71,570,952...71,647,915
Ensembl chr 5:71,514,858...71,647,763 		JBrowse link
G Tmem45b transmembrane protein 45b decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEM45B mRNA CTD PMID:26377693 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453 		JBrowse link
G Tnni3 troponin I3, cardiac type decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TNNI3 mRNA CTD PMID:26377693 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TNNT2 mRNA CTD PMID:26377693 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tox2 TOX high mobility group box family member 2 multiple interactions ISO [indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of TOX2 mRNA CTD PMID:36975775 NCBI chr 3:151,853,294...151,980,086
Ensembl chr 3:151,853,294...151,980,749 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TRPV4 mRNA CTD PMID:26377693 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TSC22D3 mRNA CTD PMID:26377693 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tspear thrombospondin-type laminin G domain and EAR repeats increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of TSPEAR mRNA CTD PMID:32251684 NCBI chr20:10,771,806...10,837,419
Ensembl chr20:10,772,219...10,943,914 		JBrowse link
G Ucp1 uncoupling protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of UCP1 mRNA CTD PMID:26377693 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
G Upk3b uroplakin 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of UPK3B mRNA CTD PMID:26377693 NCBI chr12:20,630,231...20,637,634
Ensembl chr12:20,631,525...20,637,724 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of VAV3 mRNA CTD PMID:21635667 NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321 		JBrowse link
G Wdr62 WD repeat domain 62 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of WDR62 mRNA CTD PMID:26377693 NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637 		JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of WT1 mRNA CTD PMID:26377693 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of XBP1 mRNA CTD PMID:32251684 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Zdhhc22 zinc finger DHHC-type palmitoyltransferase 22 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ZDHHC22 mRNA CTD PMID:26377693 NCBI chr 6:106,629,090...106,646,996
Ensembl chr 6:106,631,609...106,638,872 		JBrowse link
G Zfp628 zinc finger protein 628 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ZFP628 mRNA CTD PMID:26377693 NCBI chr 1:68,913,600...68,921,186
Ensembl chr 1:68,910,401...68,921,243 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19839
      group 19798
        polyatomic entity 19797
          molecule 19701
            cyclic compound 19516
              organic cyclic compound 19498
                organic polycyclic compound 17247
                  pyrenes 323
                    Indeno[1,2,3-cd]pyrene 236
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      p-block molecular entity 19789
                        carbon group molecular entity 19737
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic polycyclic compound 17247
                                  pyrenes 323
                                    Indeno[1,2,3-cd]pyrene 236
paths to the root