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Gene: Shc3 (SHC adaptor protein 3) Rattus norvegicus
Symbol: Shc3
Name: SHC adaptor protein 3
Description: Predicted to have phosphotyrosine residue binding activity and receptor tyrosine kinase binding activity. Predicted to be involved in glutamatergic synaptic transmission; learning or memory; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to plasma membrane. Orthologous to human SHC3 (SHC adaptor protein 3); PARTICIPATES IN chemokine mediated signaling pathway; chronic myeloid leukemia pathway; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 3H-1,2-dithiole-3-thione.
Type: protein-coding
Also known as: N-Shc; neuronal Shc; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHC-transforming protein 3; SHC-transforming protein C; ShcC; src homology 2 domain-containing transforming; src homology 2 domain-containing transforming protein C3; src homology 2 domain-containing-transforming protein C3
Homo sapiens (human) : SHC3 (SHC adaptor protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Shc3 (src homology 2 domain-containing transforming protein C3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shc3 (SHC adaptor protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SHC3 (SHC adaptor protein 3)
Canis lupus familiaris (dog) : SHC3 (SHC adaptor protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shc3 (SHC adaptor protein 3)
Sus scrofa (pig) : SHC3 (SHC adaptor protein 3)
Chlorocebus sabaeus (African green monkey) : SHC3 (SHC adaptor protein 3)
Heterocephalus glaber (naked mole-rat) : Shc3 (SHC adaptor protein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01713,670,520 - 13,791,043 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,670,520 - 13,791,043 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,743,125 - 15,862,911 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,520,861 - 19,649,482 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11719,520,646 - 19,649,496 (+)NCBI
Celera1713,401,154 - 13,520,906 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Shc3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69348
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.