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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrenes
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Accession:CHEBI:59659 term browser browse the term



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1,3-Dinitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 1,3-dinitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation
increases phosphorylation
ISO 1,3-dinitropyrene results in decreased phosphorylation of BAD protein
1,3-dinitropyrene results in increased phosphorylation of BAD protein
CTD PMID:17240030 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO 1,3-dinitropyrene results in decreased expression of BCL2L1 protein CTD PMID:17240030 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO 1,3-dinitropyrene results in decreased expression of BID protein CTD PMID:17240030 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 1,3-dinitropyrene results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17240030 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 1,3-dinitropyrene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:17240030 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects metabolic processing
increases expression
ISO
EXP
[CYP1A1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene
CYP1A1 protein affects the metabolism of 1,3-dinitropyrene
1,3-dinitropyrene results in increased expression of CYP1A1 protein
1,3-dinitropyrene results in increased expression of CYP1A1 mRNA
CTD PMID:2180560 PMID:11113705 PMID:12107646 PMID:17240030 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects metabolic processing
ISO
EXP
[CYP1A2 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene
CYP1A2 protein affects the metabolism of 1,3-dinitropyrene
CTD PMID:2180560 PMID:11113705 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene CTD PMID:11113705 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO 1,3-dinitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects response to substance
increases reduction
EXP NQO1 protein affects the susceptibility to 1,3-dinitropyrene
NQO1 protein results in increased reduction of 1,3-dinitropyrene
CTD PMID:1774770 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [CYP1A1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene; [CYP1A2 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene; [CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene CTD PMID:11113705 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation
affects localization
ISO 1,3-dinitropyrene results in increased phosphorylation of TRP53 protein
1,3-dinitropyrene affects the localization of TRP53 protein
CTD PMID:17240030 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
1,6-Dinitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects metabolic processing
increases expression
EXP
ISO
CYP1A1 protein affects the metabolism of 1,6-dinitropyrene
1,6-dinitropyrene results in increased expression of CYP1A1 mRNA
CTD PMID:2180560 PMID:12107646 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing EXP CYP1A2 protein affects the metabolism of 1,6-dinitropyrene CTD PMID:2180560 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of 1,6-dinitropyrene CTD PMID:2180560 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases response to substance
increases reduction
EXP NQO1 protein results in increased susceptibility to 1,6-dinitropyrene
NQO1 protein results in increased reduction of 1,6-dinitropyrene
CTD PMID:1774770 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
1,8-Dinitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 1,8-dinitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO 1,8-dinitropyrene results in increased expression of BID protein CTD PMID:17240030 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
affects metabolic processing
ISO
EXP
[CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene
1,8-dinitropyrene results in increased expression of CYP1A1 protein
1,8-dinitropyrene results in increased expression of CYP1A1 mRNA
CYP1A1 protein affects the metabolism of 1,8-dinitropyrene
CTD PMID:2180560 PMID:11113705 PMID:12107646 PMID:17240030 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing EXP CYP1A2 protein affects the metabolism of 1,8-dinitropyrene CTD PMID:2180560 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO 1,8-dinitropyrene results in increased expression of CYP1B1 mRNA
[CYP1B1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene
CTD PMID:11113705 PMID:21887816 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ereg epiregulin increases expression ISO 1,8-dinitropyrene results in increased expression of EREG mRNA CTD PMID:21887816 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases response to substance
increases reduction
EXP NQO1 protein results in increased susceptibility to 1,8-dinitropyrene
NQO1 protein results in increased reduction of 1,8-dinitropyrene
CTD PMID:1774770 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene; [CYP1B1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene CTD PMID:11113705 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO 1,8-dinitropyrene results in increased expression of TIPARP mRNA CTD PMID:21887816 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation ISO 1,8-dinitropyrene results in increased phosphorylation of TRP53 protein CTD PMID:17240030 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
1-Hydroxypyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 increases secretion
multiple interactions
ISO ABCG2 protein results in increased secretion of 1-hydroxypyrene metabolite
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased secretion of 1-hydroxypyrene metabolite]
CTD PMID:24140465 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 decreases expression ISO 1-hydroxypyrene results in decreased expression of AIFM3 mRNA CTD PMID:21854004 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248
JBrowse link
G Ar androgen receptor multiple interactions ISO 1-hydroxypyrene binds to and results in decreased activity of AR protein; 1-hydroxypyrene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 1-hydroxypyrene inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 PMID:27436773 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arfgap2 ADP-ribosylation factor GTPase activating protein 2 decreases expression ISO 1-hydroxypyrene results in decreased expression of ARFGAP2 mRNA CTD PMID:21854004 NCBI chr 3:77,236,305...77,248,445
Ensembl chr 3:77,236,322...77,248,455
JBrowse link
G Asxl2 ASXL transcriptional regulator 2 decreases expression ISO 1-hydroxypyrene results in decreased expression of ASXL2 mRNA CTD PMID:21854004 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477
JBrowse link
G C3 complement C3 increases expression ISO 1-hydroxypyrene results in increased expression of C3 mRNA CTD PMID:22989670 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Cldn15 claudin 15 decreases expression ISO 1-hydroxypyrene results in decreased expression of CLDN15 mRNA CTD PMID:21854004 NCBI chr12:19,698,169...19,708,419
Ensembl chr12:19,698,337...19,706,819
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases secretion ISO CYP1A1 gene polymorphism results in decreased secretion of 1-hydroxypyrene CTD PMID:21787681 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Dazap1 DAZ associated protein 1 decreases expression ISO 1-hydroxypyrene results in decreased expression of DAZAP1 mRNA CTD PMID:21854004 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G E4f1 E4F transcription factor 1 decreases expression ISO 1-hydroxypyrene results in decreased expression of E4F1 mRNA CTD PMID:21854004 NCBI chr10:13,471,478...13,495,018
Ensembl chr10:13,474,456...13,485,974
JBrowse link
G Erp27 endoplasmic reticulum protein 27 decreases expression ISO 1-hydroxypyrene results in decreased expression of ERP27 mRNA CTD PMID:21854004 NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 1-hydroxypyrene binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO 1-hydroxypyrene binds to and results in increased activity of ESR2 protein; 1-hydroxypyrene inhibits the reaction [ESR2 protein binds to Estradiol]
ESR2 protein binds to 1-hydroxypyrene
CTD PMID:22989670 PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Faap100 FA core complex associated protein 100 decreases expression ISO 1-hydroxypyrene results in decreased expression of FAAP100 mRNA CTD PMID:21854004 NCBI chr10:105,641,677...105,653,809
Ensembl chr10:105,639,414...105,653,494
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in decreased expression of FOXP3 mRNA CTD PMID:30951957 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fst follistatin multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in increased expression of FST protein CTD PMID:31228248 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Gimap6 GTPase, IMAP family member 6 increases expression ISO 1-hydroxypyrene results in increased expression of GIMAP6 mRNA CTD PMID:21854004 NCBI chr 4:77,653,703...77,659,112
Ensembl chr 4:77,652,610...77,659,116
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases secretion ISO GSTM1 gene polymorphism results in decreased secretion of 1-hydroxypyrene CTD PMID:21787681 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases secretion ISO GSTP1 gene polymorphism results in decreased secretion of 1-hydroxypyrene CTD PMID:21787681 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Haghl hydroxyacylglutathione hydrolase-like decreases expression ISO 1-hydroxypyrene results in decreased expression of HAGHL mRNA CTD PMID:21854004 NCBI chr10:14,804,957...14,809,495
Ensembl chr10:14,804,997...14,807,665
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in increased expression of HSPB1 protein CTD PMID:31228248 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Il16 interleukin 16 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in increased expression of IL16 protein CTD PMID:31228248 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Itsn2 intersectin 2 increases expression ISO 1-hydroxypyrene results in increased expression of ITSN2 mRNA CTD PMID:21854004 NCBI chr 6:27,616,645...27,727,373
Ensembl chr 6:27,600,406...27,727,124
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO 1-hydroxypyrene results in decreased expression of JAG1 mRNA CTD PMID:22989670 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G LOC686030 hypothetical protein LOC686030 decreases expression ISO 1-hydroxypyrene results in decreased expression of C2ORF66 mRNA CTD PMID:21854004 NCBI chr 9:55,945,806...55,949,855
Ensembl chr 9:55,948,303...55,949,643
JBrowse link
G Lrp12 LDL receptor related protein 12 decreases expression ISO 1-hydroxypyrene results in decreased expression of LRP12 mRNA CTD PMID:21854004 NCBI chr 7:70,941,068...71,012,409
Ensembl chr 7:70,941,068...71,012,441
JBrowse link
G Myo15b myosin XVB decreases expression ISO 1-hydroxypyrene results in decreased expression of MYO15B mRNA CTD PMID:21854004 NCBI chr10:101,088,904...101,126,159 JBrowse link
G Nipal4 NIPA-like domain containing 4 increases expression ISO 1-hydroxypyrene results in increased expression of NIPAL4 mRNA CTD PMID:21854004 NCBI chr10:30,583,926...30,600,640
Ensembl chr10:30,583,926...30,600,640
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 1-hydroxypyrene binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 1-hydroxypyrene results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO 1-hydroxypyrene results in increased expression of NRIP1 mRNA CTD PMID:22989670 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Pgr progesterone receptor multiple interactions ISO 1-hydroxypyrene inhibits the reaction [Progesterone binds to PGR protein]; [Progesterone co-treated with 1-hydroxypyrene] results in decreased expression of PGR mRNA CTD PMID:9144411 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phf2 PHD finger protein 2 increases expression ISO 1-hydroxypyrene results in increased expression of PHF2 mRNA CTD PMID:21854004 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 1-hydroxypyrene binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO 1-hydroxypyrene results in increased expression of PTGR1 mRNA CTD PMID:21854004 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases expression ISO 1-hydroxypyrene results in decreased expression of SLC12A7 mRNA CTD PMID:21854004 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
JBrowse link
G Slc25a34 solute carrier family 25, member 34 decreases expression ISO 1-hydroxypyrene results in decreased expression of SLC25A34 mRNA CTD PMID:21854004 NCBI chr 5:153,932,081...153,936,854 JBrowse link
G Spns3 sphingolipid transporter 3 decreases expression ISO 1-hydroxypyrene results in decreased expression of SPNS3 mRNA CTD PMID:21854004 NCBI chr10:57,114,247...57,169,056
Ensembl chr10:57,114,266...57,168,951
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases activity
increases sulfation
increases metabolic processing
multiple interactions
ISO 1-hydroxypyrene results in decreased activity of SULT1A1 protein
SULT1A1 protein results in increased sulfation of 1-hydroxypyrene
SULT1A1 protein results in increased metabolism of 1-hydroxypyrene
acetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT1A1 protein]; Methanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]
CTD PMID:14570759 PMID:24140465 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases metabolic processing ISO SULT1B1 protein results in increased metabolism of 1-hydroxypyrene CTD PMID:24140465 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions
decreases activity
increases sulfation
ISO acetonitrile promotes the reaction [SULT1E1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol inhibits the reaction [SULT1E1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT1E1 protein] CTD PMID:14570759 PMID:16914110 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO Dimethylformamide inhibits the reaction [SULT2A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol inhibits the reaction [SULT2A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT2A1 protein] CTD PMID:14570759 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in decreased expression of TGFB1 mRNA CTD PMID:30951957 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO 1-hydroxypyrene binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tmem234 transmembrane protein 234 decreases expression ISO 1-hydroxypyrene results in decreased expression of TMEM234 mRNA CTD PMID:21854004 NCBI chr 5:141,942,583...141,951,047
Ensembl chr 5:141,942,655...141,951,047
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:88,762,250...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases glucuronidation ISO UGT1A6 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 increases glucuronidation ISO UGT2A1 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:21164388 NCBI chr14:20,521,018...20,545,060
Ensembl chr14:20,517,951...20,545,531
JBrowse link
G Vom1r21 vomeronasal 1 receptor 21 decreases expression ISO 1-hydroxypyrene results in decreased expression of VN1R4 mRNA CTD PMID:21854004 NCBI chr 1:60,963,939...60,964,862 JBrowse link
G Zfp335 zinc finger protein 335 decreases expression ISO 1-hydroxypyrene results in decreased expression of ZNF335 mRNA CTD PMID:21854004 NCBI chr 3:153,618,587...153,648,213
Ensembl chr 3:153,627,467...153,647,054
JBrowse link
4-Nitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO [Particulate Matter results in increased abundance of 4-nitropyrene] which results in increased secretion of TNF protein CTD PMID:32007923 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
Benzo[a]pyrene-7,8-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
increases expression
increases export
ISO [ABCC4 protein results in increased export of benzo(a)pyrene 7,8-dihydrodiol] which results in decreased chemical synthesis of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of ABCC4 mRNA; benzo(a)pyrene 7,8-dihydrodiol results in increased expression of ABCC4 protein
CTD PMID:22155354 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 multiple interactions
decreases response to substance
ISO [AKR1A1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol; AKR1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol; NAD promotes the reaction [AKR1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]; NADP promotes the reaction [AKR1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]; ponalrestat inhibits the reaction [AKR1A1 protein results in decreased susceptibility to benzo(a)pyrene 7,8-dihydrodiol] CTD PMID:15720144 PMID:21910479 PMID:22053912 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO [AKR1B1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions ISO [AKR1B10 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions ISO [AKR1C4 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol
[AKR1C1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol
CTD PMID:21910479 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 multiple interactions ISO [AKR1C2 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 multiple interactions ISO [AKR1C1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression
increases phosphorylation
ISO benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BAD protein
benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of BAD protein
CTD PMID:15698582 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BCL2L1 protein CTD PMID:15698582 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BID protein CTD PMID:15698582 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
increases chemical synthesis
ISO
EXP
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1A1 mRNA
[CYP1A1 protein results in increased metabolism of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol
[[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol
[Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] which results in increased secretion of benzo(a)pyrene 7,8-dihydrodiol; benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; CYP1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol; CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]; GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]]; hyperforin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; hypericin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; Medroxyprogesterone Acetate inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1A1 mRNA]; pseudohypericin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; Quercetin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; Ursodeoxycholic Acid inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol
CTD PMID:2154339 PMID:10706104 PMID:14633740 PMID:15720144 PMID:17525473 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
affects metabolic processing
increases chemical synthesis
increases oxidation
multiple interactions
ISO
EXP
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1B1 mRNA
CYP1B1 affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol
CYP1B1 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol
CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol
benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; bergamottin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol; imperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; isoimperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; isopimpinellin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; NADP promotes the reaction [CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]
CTD PMID:15720144 PMID:15861043 PMID:19879933 PMID:21028851 PMID:24025706 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO [[CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] which results in increased abundance of benzo(a)pyrene-7,8,9,10-tetrol; [[CYP2S1 protein co-treated with Hydrogen Peroxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] which results in increased abundance of benzo(a)pyrene-7,8,9,10-tetrol; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:19713358 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
affects metabolic processing
ISO [benzo(a)pyrene 7,8-dihydrodiol binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [CYP3A4 protein results in increased metabolism of Benzo(a)pyrene] which results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol; CYP3A4 protein results in increased metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol
CYP3A4 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol
CTD PMID:2271712 PMID:2509067 PMID:2655891 PMID:23845848 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:24530354 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP benzo(a)pyrene 7,8-dihydrodiol results in increased expression of GSTA1 mRNA CTD PMID:11008122 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]] CTD PMID:17525473 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]; GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]] CTD PMID:17525473 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO benzo(a)pyrene 7,8-dihydrodiol results in increased expression of HRAS mRNA CTD PMID:11008122 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of MAPK14 protein CTD PMID:15698582 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of MAPK8 protein CTD PMID:15698582 PMID:22053912 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO
EXP
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of NQO1 mRNA CTD PMID:11008122 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [benzo(a)pyrene 7,8-dihydrodiol binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; benzo(a)pyrene 7,8-dihydrodiol binds to and results in increased activity of NR1I2 protein CTD PMID:23845848 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased cleavage of PARP1 protein] CTD PMID:15572374 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:24530354 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases metabolic processing ISO PTGS1 protein results in increased metabolism of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:11159734 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases metabolic processing ISO PTGS2 protein results in increased metabolism of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:11159734 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP TNF protein inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol] CTD PMID:24025706 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases chemical synthesis
ISO [TP53 protein results in increased susceptibility to Etoposide] which results in decreased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol; benzo(a)pyrene 7,8-dihydrodiol results in increased expression of and results in increased phosphorylation of TP53 protein; Etoposide promotes the reaction [TP53 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol] CTD PMID:15698582 PMID:29471073 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 increases glucuronidation ISO UGT2A1 protein results in increased glucuronidation of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21164388 NCBI chr14:20,521,018...20,545,060
Ensembl chr14:20,517,951...20,545,531
JBrowse link
benzo[a]pyrene-7,8-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions
ISO benzo(a)pyrene-7,8-dione affects the localization of AHR protein
AHR protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA]
CTD PMID:10706104 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases chemical synthesis
multiple interactions
affects chemical synthesis
increases expression
ISO AKR1A1 protein results in increased chemical synthesis of benzo(a)pyrene-7,8-dione
[AKR1A1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione; AKR1A1 protein results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione; NAD promotes the reaction [AKR1A1 protein affects the chemical synthesis of benzo(a)pyrene-7,8-dione]
benzo(a)pyrene-7,8-dione results in increased expression of AKR1A1 mRNA
CTD PMID:9973208 PMID:15720144 PMID:16411658 PMID:21910479 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO [AKR1B1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions ISO [AKR1B10 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions
increases expression
ISO [AKR1C4 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione
benzo(a)pyrene-7,8-dione results in increased expression of AKR1C1 mRNA
[AKR1C1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione
CTD PMID:9973208 PMID:21910479 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 multiple interactions ISO [AKR1C2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 increases expression
multiple interactions
ISO benzo(a)pyrene-7,8-dione results in increased expression of AKR1C1 mRNA
[AKR1C1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione
CTD PMID:9973208 PMID:21910479 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 multiple interactions ISO [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione] which results in decreased abundance of Oxygen; [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione] which results in increased chemical synthesis of Hydrogen Peroxide; [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione] which results in increased chemical synthesis of Superoxides; [AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions ISO [AKR7A3 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA] CTD PMID:10706104 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO AHR protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA]; ARNT protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA] CTD PMID:9973208 PMID:10706104 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO benzo(a)pyrene-7,8-dione results in increased expression of and results in increased activity of CYP1B1 protein
benzo(a)pyrene-7,8-dione results in increased expression of CYP1B1 mRNA
CTD PMID:16411658 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]; Ascorbic Acid inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]
benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 mRNA; benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein
CTD PMID:22053912 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO benzo(a)pyrene-7,8-dione results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:12213569 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO benzo(a)pyrene-7,8-dione results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:12213569 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO benzo(a)pyrene-7,8-dione results in increased expression of NQO1 mRNA; benzo(a)pyrene-7,8-dione results in increased expression of NQO1 protein
[NQO1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione
CTD PMID:21910479 PMID:22053912 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases metabolic processing ISO SULT1A1 protein results in increased metabolism of benzo(a)pyrene-7,8-dione CTD PMID:22782890 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 increases metabolic processing ISO SULT1E1 protein results in increased metabolism of benzo(a)pyrene-7,8-dione CTD PMID:22782890 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
Benzo[a]pyrene-7,8-oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7,8-oxide] CTD PMID:12051674 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7,8-oxide] CTD PMID:12051674 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
Cyclopenta[cd]pyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP cyclopenta(c,d)pyrene binds to and results in increased activity of AHR protein CTD PMID:11525907 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO cyclopenta(c,d)pyrene results in increased mutagenesis of KRAS gene CTD PMID:9659573 NCBI chr 4:178,185,418...178,218,484 JBrowse link
Indeno[1,2,3-cd]pyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ABCC5 mRNA CTD PMID:32251684 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ACSM3 mRNA CTD PMID:26377693 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADAMTS15 mRNA CTD PMID:26377693 NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249
JBrowse link
G Adig adipogenin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADIG mRNA CTD PMID:26377693 NCBI chr 3:147,155,021...147,160,413 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADIPOQ mRNA CTD PMID:26377693 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADORA1 mRNA CTD PMID:32251684 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO
EXP
[benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [indeno(1,2,3-cd)pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene] promotes the reaction [pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with pyrene] promotes the reaction [fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [chrysene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(k)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(j)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; [Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benz(a)anthracene results in increased activity of AHR protein]; indeno(1,2,3-cd)pyrene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]
indeno(1,2,3-cd)pyrene binds to and results in increased activity of AHR protein
CTD PMID:11525907 PMID:12371477 PMID:12850102 PMID:17665671 PMID:21781905 More... NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AHRR mRNA CTD PMID:32251684 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AKR1C1 mRNA CTD PMID:17253728 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AKR1C1 mRNA CTD PMID:17253728 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ALDH1A2 mRNA CTD PMID:26377693 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ALDH1A3 mRNA CTD PMID:32251684 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ALDH3A1 mRNA CTD PMID:32251684 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Amer2 APC membrane recruitment protein 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AMER2 mRNA CTD PMID:32251684 NCBI chr15:34,525,090...34,535,660
Ensembl chr15:34,524,542...34,528,455
JBrowse link
G Amy1a amylase, alpha 1A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of AMY1 mRNA CTD PMID:26377693 NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816
JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ANGPTL4 mRNA CTD PMID:26377693 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Areg amphiregulin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of AREG mRNA CTD PMID:26377693 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ARL4D mRNA CTD PMID:26377693 NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ARNTL mRNA CTD PMID:26377693 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ASGR2 mRNA CTD PMID:26377693 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ATOH8 mRNA CTD PMID:32251684 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BAIAP2L1 mRNA CTD PMID:26377693 NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
JBrowse link
G Bche butyrylcholinesterase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BCHE mRNA CTD PMID:26377693 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BCL6 mRNA CTD PMID:26377693 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bnc1 basonuclin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BNC1 mRNA CTD PMID:26377693 NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333
JBrowse link
G Bpifa1 BPI fold containing family A, member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BPIFA1 mRNA CTD PMID:26377693 NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552
JBrowse link
G C2 complement C2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of C2 mRNA CTD PMID:26377693 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CAR14 mRNA CTD PMID:26377693 NCBI chr 2:183,442,263...183,449,207
Ensembl chr 2:183,441,667...183,449,693
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CAR3 mRNA CTD PMID:26377693 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Cacybp calcyclin binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CACYBP mRNA CTD PMID:26377693 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CADM1 mRNA CTD PMID:21635667 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCDC80 mRNA CTD PMID:26377693 NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137
JBrowse link
G Ccdc85a coiled-coil domain containing 85A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCDC85A mRNA CTD PMID:26377693 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCNA2 mRNA CTD PMID:32251684 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccng2 cyclin G2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CCNG2 mRNA CTD PMID:32251684 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccnjl cyclin J-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCNJL mRNA CTD PMID:26377693 NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CEBPB mRNA CTD PMID:32251684 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CEBPD mRNA CTD PMID:26377693 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CELSR2 mRNA CTD PMID:21635667 PMID:32251684 NCBI chr 2:196,029,206...196,053,848
Ensembl chr 2:196,029,434...196,053,845
JBrowse link
G Cenpa centromere protein A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CENPA mRNA CTD PMID:32251684 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cfd complement factor D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CFD mRNA CTD PMID:26377693 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CHORDC1 mRNA CTD PMID:26377693 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CIDEA mRNA CTD PMID:26377693 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CKMT2 mRNA CTD PMID:26377693 NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430
JBrowse link
G Cldn17 claudin 17 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLDN17 mRNA CTD PMID:21635667 NCBI chr11:27,827,454...27,828,630
Ensembl chr11:27,827,454...27,828,630
JBrowse link
G Clec10a C-type lectin domain containing 10A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLEC10A mRNA CTD PMID:26377693 NCBI chr10:54,876,244...54,880,439
Ensembl chr10:54,876,260...54,880,435
JBrowse link
G Clec9a C-type lectin domain containing 9A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLEC9A mRNA CTD PMID:26377693 NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352
JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLIC4 mRNA CTD PMID:26377693 NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COL2A1 mRNA CTD PMID:21635667 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Col4a6 collagen type IV alpha 6 chain decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COL4A6 mRNA CTD PMID:21635667 NCBI chr  X:104,766,463...105,117,499
Ensembl chr  X:104,766,957...105,117,500
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COX7A1 mRNA CTD PMID:26377693 NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CREB1 mRNA CTD PMID:32251684 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CSRP3 mRNA CTD PMID:26377693 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Ctsb cathepsin B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CTSB mRNA CTD PMID:32251684 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CTSD mRNA CTD PMID:32251684 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CXCL12 mRNA CTD PMID:32251684 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CXCL5 mRNA CTD PMID:26377693 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO
EXP
Dexamethasone inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 protein]; indeno(1,2,3-cd)pyrene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]
indeno(1,2,3-cd)pyrene results in increased activity of CYP1A1 protein
indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 protein
CTD PMID:10190573 PMID:17253728 PMID:19463884 PMID:21781905 PMID:26377693 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CYP1A2 mRNA CTD PMID:17253728 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 mRNA CTD PMID:17253728 PMID:27196671 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of DDIT4 mRNA CTD PMID:32251684 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DGAT2 mRNA CTD PMID:26377693 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dnaaf10 dynein axonemal assembly factor 10 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DNAAF10 mRNA CTD PMID:26377693 NCBI chr14:91,618,649...91,639,828
Ensembl chr14:91,636,157...91,639,831
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DNAJA1 mRNA CTD PMID:26377693 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dpt dermatopontin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DPT mRNA CTD PMID:26377693 NCBI chr13:77,122,926...77,151,646
Ensembl chr13:77,123,115...77,151,639
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DVL3 mRNA CTD PMID:26377693 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DYNLL1 mRNA CTD PMID:26377693 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of EFEMP1 mRNA CTD PMID:26377693 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ELOVL6 mRNA CTD PMID:26377693 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Ephb6 Eph receptor B6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of EPHB6 mRNA CTD PMID:26377693 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ERBB2 mRNA CTD PMID:21635667 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ERRFI1 mRNA CTD PMID:26377693 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO indeno(1,2,3-cd)pyrene binds to ESR1 protein CTD PMID:32251684 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA] CTD PMID:21635667 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FABP4 mRNA CTD PMID:26377693 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fam181b family with sequence similarity 181, member B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FAM181B mRNA CTD PMID:26377693 NCBI chr 1:147,166,428...147,167,925
Ensembl chr 1:147,124,740...147,168,298
Ensembl chr 1:147,124,740...147,168,298
JBrowse link
G Fibin fin bud initiation factor homolog decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FIBIN mRNA CTD PMID:26377693 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FOS mRNA CTD PMID:32251684 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Frem1 Fras1 related extracellular matrix 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FREM1 mRNA CTD PMID:21635667 NCBI chr 5:97,321,275...97,469,523
Ensembl chr 5:97,322,538...97,469,543
JBrowse link
G Fsbp fibrinogen silencer binding protein increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of FSBP mRNA CTD PMID:32251684 NCBI chr 5:25,058,003...25,064,283 JBrowse link
G Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GDPD2 mRNA CTD PMID:26377693 NCBI chr  X:65,826,273...65,835,361
Ensembl chr  X:65,826,574...65,835,361
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GFPT2 mRNA CTD PMID:26377693 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of GJB2 mRNA CTD PMID:32251684 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Golph3l golgi phosphoprotein 3-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GOLPH3L mRNA CTD PMID:26377693 NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GPD1 mRNA CTD PMID:26377693 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GPM6A mRNA CTD PMID:26377693 NCBI chr16:36,641,282...36,973,477
Ensembl chr16:36,641,284...36,973,475
JBrowse link
G Grifin galectin-related inter-fiber protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GRIFIN mRNA CTD PMID:26377693 NCBI chr12:14,080,170...14,082,892
Ensembl chr12:14,080,910...14,082,877
JBrowse link
G Grp gastrin releasing peptide decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GRP mRNA CTD PMID:26377693 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
JBrowse link
G Gxylt2 glucoside xylosyltransferase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GXYLT2 mRNA CTD PMID:26377693 NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454
JBrowse link
G Gzma granzyme A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GZMA mRNA CTD PMID:26377693 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G Has1 hyaluronan synthase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HAS1 mRNA CTD PMID:26377693 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of HMOX1 mRNA CTD PMID:32251684 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hrc histidine rich calcium binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HRC mRNA CTD PMID:26377693 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSP90AA1 mRNA CTD PMID:26377693 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPA1A mRNA CTD PMID:26377693
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPA8 mRNA CTD PMID:26377693 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPD1 mRNA CTD PMID:26377693 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPH1 mRNA CTD PMID:26377693 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ier3 immediate early response 3 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IER3 mRNA CTD PMID:22579512 PMID:32251684 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IGF1R mRNA CTD PMID:32251684 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IGFBP5 mRNA CTD PMID:26377693 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IQSEC1 mRNA CTD PMID:26377693 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IRF2BP2 mRNA CTD PMID:26377693 NCBI chr19:54,559,409...54,564,714 JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA] CTD PMID:21635667 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itga6 integrin subunit alpha 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ITGA6 mRNA CTD PMID:26377693 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itgb6 integrin subunit beta 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ITGB6 mRNA CTD PMID:26377693 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of JCHAIN mRNA CTD PMID:26377693 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA] CTD PMID:21635667 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kdm1b lysine demethylase 1B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KDM1B mRNA CTD PMID:26377693 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800
JBrowse link
G Kitlg KIT ligand decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KITL mRNA CTD PMID:26377693 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klhl23 kelch-like family member 23 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PHOSPHO2-KLHL23 mRNA CTD PMID:32251684 NCBI chr 3:54,580,788...54,594,530
Ensembl chr 3:54,580,961...54,594,530
JBrowse link
G Klk1 kallikrein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KLK1 mRNA CTD PMID:26377693 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KNSTRN mRNA CTD PMID:26377693 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
JBrowse link
G Krt19 keratin 19 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KRT19 mRNA CTD PMID:32251684 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Lgals1 galectin 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of LGALS1 mRNA CTD PMID:22579512 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G LOC100361240 ribosomal protein S10-like increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RPS10-NUDT3 mRNA CTD PMID:32251684 NCBI chr15:18,308,287...18,309,139 JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LONRF3 mRNA CTD PMID:26377693 NCBI chr  X:115,565,214...115,603,886
Ensembl chr  X:115,565,267...115,598,809
JBrowse link
G Lpin2 lipin 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LPIN2 mRNA CTD PMID:26377693 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LRRN4 mRNA CTD PMID:26377693 NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
multiple interactions
ISO indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein
Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]
CTD PMID:21635667 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mb myoglobin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MB mRNA CTD PMID:26377693 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of MDM2 mRNA CTD PMID:32251684 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mef2b myocyte enhancer factor 2B increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of MEF2B mRNA CTD PMID:32251684 NCBI chr16:19,253,008...19,269,514
Ensembl chr16:19,253,010...19,268,967
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MFAP2 mRNA CTD PMID:26377693 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mgat1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MGAT1 mRNA CTD PMID:26377693 NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA] CTD PMID:21635667 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MMP3 mRNA CTD PMID:26377693 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MNDA mRNA CTD PMID:26377693 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
JBrowse link
G Mrap melanocortin 2 receptor accessory protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MRAP mRNA CTD PMID:26377693 NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024
JBrowse link
G Msln mesothelin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MSLN mRNA CTD PMID:26377693 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MTARC1 mRNA CTD PMID:26377693 NCBI chr13:96,324,377...96,362,677 JBrowse link
G Muc16 mucin 16, cell surface associated decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MUC16 mRNA CTD PMID:26377693 NCBI chr 8:16,164,531...16,323,126 JBrowse link
G Mybpc3 myosin binding protein C3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYBPC3 mRNA CTD PMID:26377693 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYH6 mRNA CTD PMID:26377693 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myl1 myosin, light chain 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL1 mRNA CTD PMID:26377693 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261
JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL4 mRNA CTD PMID:26377693 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Myl7 myosin light chain 7 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL7 mRNA CTD PMID:26377693 NCBI chr14:80,780,684...80,783,259
Ensembl chr14:80,779,776...80,783,244
JBrowse link
G Mylk myosin light chain kinase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYLK mRNA CTD PMID:21635667 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NDC80 mRNA CTD PMID:22579512 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NEDD4 mRNA CTD PMID:26377693 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NFIL3 mRNA CTD PMID:26377693 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of NQO1 mRNA CTD PMID:17253728 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of OASL1 mRNA CTD PMID:26377693 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Otop1 otopetrin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of OTOP1 mRNA CTD PMID:26377693 NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PAH mRNA CTD PMID:22579512 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Pals2 protein associated with LIN7 2, MAGUK p55 family member decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PALS2 mRNA CTD PMID:26377693 NCBI chr 4:79,173,488...79,257,542
Ensembl chr 4:79,124,806...79,254,140
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO indeno(1,2,3-cd)pyrene results in increased cleavage of PARP1 protein CTD PMID:21132278 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PBX1 mRNA CTD PMID:26377693 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PCK1 mRNA CTD PMID:26377693 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pde5a phosphodiesterase 5A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDE5A mRNA CTD PMID:26377693 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDK4 mRNA CTD PMID:26377693 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdzd2 PDZ domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDZD2 mRNA CTD PMID:26377693 NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:61,386,381...61,770,524
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PEBP1 mRNA CTD PMID:26377693 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Penk proenkephalin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PENK mRNA CTD PMID:26377693 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Pgam2 phosphoglycerate mutase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGAM2 mRNA CTD PMID:26377693 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGAP2 mRNA CTD PMID:26377693 NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114
JBrowse link
G Pgr progesterone receptor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGR mRNA CTD PMID:32251684 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phf19 PHD finger protein 19 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PHF19 mRNA CTD PMID:32251684 NCBI chr 3:18,175,281...18,197,289
Ensembl chr 3:18,175,282...18,196,405
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PKIB mRNA CTD PMID:32251684 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
JBrowse link
G Plin1 perilipin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PLIN1 mRNA CTD PMID:26377693 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Plin4 perilipin 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PLIN4 mRNA CTD PMID:26377693 NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of POLR1B mRNA CTD PMID:26377693 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379
JBrowse link
G Popdc2 popeye domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of POPDC2 mRNA CTD PMID:26377693 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756
JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PPP4R3B mRNA CTD PMID:26377693 NCBI chr14:102,917,043...102,965,210
Ensembl chr14:102,917,443...103,068,192
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RARA mRNA CTD PMID:32251684 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Reln reelin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RELN mRNA CTD PMID:21635667 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Ret ret proto-oncogene decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RET mRNA CTD PMID:32251684 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Retn resistin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RETN mRNA CTD PMID:26377693 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rhoc ras homolog family member C increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RHOC mRNA CTD PMID:22579512 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RORA mRNA CTD PMID:26377693 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rprml reprimo-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RPRML mRNA CTD PMID:26377693 NCBI chr10:88,560,248...88,561,252
Ensembl chr10:88,560,248...88,561,252
JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RSRP1 mRNA CTD PMID:26377693 NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RUNX2 mRNA CTD PMID:32251684 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sbsn suprabasin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SBSN mRNA CTD PMID:26377693 NCBI chr 1:85,979,477...86,006,034
Ensembl chr 1:86,001,567...86,006,034
JBrowse link
G Sdcbp2 syndecan binding protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SDCBP2 mRNA CTD PMID:26377693 NCBI chr 3:140,060,746...140,098,063
Ensembl chr 3:140,070,540...140,098,057
JBrowse link
G Sema3b semaphorin 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SEMA3B mRNA CTD PMID:32251684 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919
JBrowse link
G Septin3 septin 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SEPTIN3 mRNA CTD PMID:26377693 NCBI chr 7:113,783,217...113,811,089
Ensembl chr 7:113,783,095...113,811,087
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SGK1 mRNA CTD PMID:32251684 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Shc3 SHC adaptor protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SHC3 mRNA CTD PMID:21635667 NCBI chr17:13,652,247...13,772,710
Ensembl chr17:13,651,202...13,772,710
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SIAH2 mRNA CTD PMID:32251684 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Slc10a6 solute carrier family 10 member 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC10A6 mRNA CTD PMID:26377693 NCBI chr14:6,080,716...6,102,037
Ensembl chr14:6,080,717...6,103,037
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC1A5 mRNA CTD PMID:26377693 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC2A4 mRNA CTD PMID:26377693 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC2A5 mRNA CTD PMID:26377693 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc5a12 solute carrier family 5 member 12 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC5A12 mRNA CTD PMID:26377693 NCBI chr 3:97,179,326...97,228,405
Ensembl chr 3:97,179,326...97,228,405
JBrowse link
G Slc5a3 solute carrier family 5 member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC5A3 mRNA CTD PMID:26377693 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of SLC7A11 mRNA CTD PMID:32251684 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of SLC7A5 mRNA CTD PMID:32251684 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Sln sarcolipin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLN mRNA CTD PMID:26377693 NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SMPD3 mRNA CTD PMID:26377693 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA] CTD PMID:21635667 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SOX17 mRNA CTD PMID:26377693 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of STC2 mRNA CTD PMID:32251684 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of STIP1 mRNA CTD PMID:26377693 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SULF1 mRNA CTD PMID:26377693 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Syt1 synaptotagmin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SYT1 mRNA CTD PMID:26377693 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
G Tfap2c transcription factor AP-2 gamma decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFAP2C mRNA CTD PMID:32251684 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFF1 mRNA CTD PMID:32251684 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tff3 trefoil factor 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFF3 mRNA CTD PMID:26377693 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of THRSP mRNA CTD PMID:26377693 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
decreases expression
ISO indeno(1,2,3-cd)pyrene results in increased expression of TIMP1 mRNA
indeno(1,2,3-cd)pyrene results in decreased expression of TIMP1 mRNA
CTD PMID:22579512 PMID:26377693 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tln2 talin 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TLN2 mRNA CTD PMID:21635667 NCBI chr 8:67,830,920...68,252,223
Ensembl chr 8:67,834,326...68,252,219
JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEFF1 mRNA CTD PMID:32251684 NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493
JBrowse link
G Tmem245 transmembrane protein 245 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEM245 mRNA CTD PMID:26377693 NCBI chr 5:71,570,952...71,647,915
Ensembl chr 5:71,514,858...71,647,763
JBrowse link
G Tmem45b transmembrane protein 45b decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEM45B mRNA CTD PMID:26377693 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453
JBrowse link
G Tnni3 troponin I3, cardiac type decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TNNI3 mRNA CTD PMID:26377693 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TNNT2 mRNA CTD PMID:26377693 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TRPV4 mRNA CTD PMID:26377693 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TSC22D3 mRNA CTD PMID:26377693 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tspear thrombospondin-type laminin G domain and EAR repeats increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of TSPEAR mRNA CTD PMID:32251684 NCBI chr20:10,771,806...10,837,419
Ensembl chr20:10,772,219...10,943,914
JBrowse link
G Ucp1 uncoupling protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of UCP1 mRNA CTD PMID:26377693 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Upk3b uroplakin 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of UPK3B mRNA CTD PMID:26377693 NCBI chr12:20,629,491...20,638,193
Ensembl chr12:20,631,525...20,637,724
JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of VAV3 mRNA CTD PMID:21635667 NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321
JBrowse link
G Wdr62 WD repeat domain 62 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of WDR62 mRNA CTD PMID:26377693 NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637
JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of WT1 mRNA CTD PMID:26377693 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of XBP1 mRNA CTD PMID:32251684 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zdhhc22 zinc finger DHHC-type palmitoyltransferase 22 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ZDHHC22 mRNA CTD PMID:26377693 NCBI chr 6:106,629,090...106,646,996
Ensembl chr 6:106,631,609...106,638,872
JBrowse link
G Zfp628 zinc finger protein 628 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ZFP628 mRNA CTD PMID:26377693 NCBI chr 1:68,913,600...68,921,186
Ensembl chr 1:68,910,401...68,921,243
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      group 19722
        polyatomic entity 19721
          molecule 19572
            cyclic compound 19379
              organic cyclic compound 19343
                organic polycyclic compound 16570
                  pyrenes 302
                    1,2-dihydropyrene-2-carboxylic acid 0
                    1,3-Dinitropyrene 13
                    1,6-Dihydroxypyrene 0
                    1,6-Dimethoxypyrene 0
                    1,6-Dinitropyrene 4
                    1,8-Dihydroxypyrene 0
                    1,8-Dinitropyrene 10
                    1-Hydroxy-6-methoxypyrene 0
                    1-Hydroxypyrene 54
                    1-Hydroxypyrene glucuronide 0
                    1-Methoxypyrene 0
                    1-Pyrenylsulfate 0
                    10-Oxabenzo[def]chrysen-9-one 0
                    2-(2-pyrenyl)acetonitrile 0
                    2-Hydroxypyrene 0
                    2-Nitropyrene 0
                    4,5-Dihydroxypyrene 0
                    4-Nitropyrene 1
                    Acepyrene 0
                    Benzo[a]pyrene-7,8-diol 31
                    Benzo[a]pyrene-7,8-oxide 2
                    Benzo[a]pyrene-9,10-oxide 0
                    Benzo[a]pyrene-cis-9,10-dihydrodiol 0
                    Cyclopenta[cd]pyrene 2
                    Indeno[1,2,3-cd]pyrene 218
                    Pyrene-1,6-dione 0
                    Pyrene-1,8-dione 0
                    Pyrene-4,5-dione 0
                    benzo[a]pyrene-7,8-dione 19
                    benzo[a]pyrene-cis-7,8-dihydrodiol + 19
                    cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate 0
                    cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      p-block molecular entity 19698
                        carbon group molecular entity 19619
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic polycyclic compound 16570
                                  pyrenes 302
                                    1,2-dihydropyrene-2-carboxylic acid 0
                                    1,3-Dinitropyrene 13
                                    1,6-Dihydroxypyrene 0
                                    1,6-Dimethoxypyrene 0
                                    1,6-Dinitropyrene 4
                                    1,8-Dihydroxypyrene 0
                                    1,8-Dinitropyrene 10
                                    1-Hydroxy-6-methoxypyrene 0
                                    1-Hydroxypyrene 54
                                    1-Hydroxypyrene glucuronide 0
                                    1-Methoxypyrene 0
                                    1-Pyrenylsulfate 0
                                    10-Oxabenzo[def]chrysen-9-one 0
                                    2-(2-pyrenyl)acetonitrile 0
                                    2-Hydroxypyrene 0
                                    2-Nitropyrene 0
                                    4,5-Dihydroxypyrene 0
                                    4-Nitropyrene 1
                                    Acepyrene 0
                                    Benzo[a]pyrene-7,8-diol 31
                                    Benzo[a]pyrene-7,8-oxide 2
                                    Benzo[a]pyrene-9,10-oxide 0
                                    Benzo[a]pyrene-cis-9,10-dihydrodiol 0
                                    Cyclopenta[cd]pyrene 2
                                    Indeno[1,2,3-cd]pyrene 218
                                    Pyrene-1,6-dione 0
                                    Pyrene-1,8-dione 0
                                    Pyrene-4,5-dione 0
                                    benzo[a]pyrene-7,8-dione 19
                                    benzo[a]pyrene-cis-7,8-dihydrodiol + 19
                                    cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate 0
                                    cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate 0
paths to the root