Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrenes
go back to main search page
Accession:CHEBI:59659 term browser browse the term


show annotations for term's descendants           Sort by:
 
1,3-Dinitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 1,3-dinitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation
increases phosphorylation
ISO 1,3-dinitropyrene results in decreased phosphorylation of BAD protein
1,3-dinitropyrene results in increased phosphorylation of BAD protein
CTD PMID:17240030 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO 1,3-dinitropyrene results in decreased expression of BCL2L1 protein CTD PMID:17240030 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO 1,3-dinitropyrene results in decreased expression of BID protein CTD PMID:17240030 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 1,3-dinitropyrene results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17240030 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 1,3-dinitropyrene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:17240030 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects metabolic processing
increases expression
ISO
EXP
[CYP1A1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene
CYP1A1 protein affects the metabolism of 1,3-dinitropyrene
1,3-dinitropyrene results in increased expression of CYP1A1 protein
1,3-dinitropyrene results in increased expression of CYP1A1 mRNA
CTD PMID:2180560, PMID:11113705, PMID:12107646, PMID:17240030 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects metabolic processing
ISO
EXP
[CYP1A2 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene
CYP1A2 protein affects the metabolism of 1,3-dinitropyrene
CTD PMID:2180560, PMID:11113705 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene CTD PMID:11113705 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO 1,3-dinitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects response to substance
increases reduction
EXP NQO1 protein affects the susceptibility to 1,3-dinitropyrene
NQO1 protein results in increased reduction of 1,3-dinitropyrene
CTD PMID:1774770 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [CYP1A1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene; [CYP1A2 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene; [CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene CTD PMID:11113705 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation
affects localization
ISO 1,3-dinitropyrene results in increased phosphorylation of TRP53 protein
1,3-dinitropyrene affects the localization of TRP53 protein
CTD PMID:17240030 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
1,6-Dinitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects metabolic processing
increases expression
EXP
ISO
CYP1A1 protein affects the metabolism of 1,6-dinitropyrene
1,6-dinitropyrene results in increased expression of CYP1A1 mRNA
CTD PMID:2180560, PMID:12107646 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing EXP CYP1A2 protein affects the metabolism of 1,6-dinitropyrene CTD PMID:2180560 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases response to substance
increases reduction
EXP NQO1 protein results in increased susceptibility to 1,6-dinitropyrene
NQO1 protein results in increased reduction of 1,6-dinitropyrene
CTD PMID:1774770 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
1,8-Dinitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 1,8-dinitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO 1,8-dinitropyrene results in increased expression of BID protein CTD PMID:17240030 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
affects metabolic processing
ISO
EXP
[CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene
1,8-dinitropyrene results in increased expression of CYP1A1 protein
1,8-dinitropyrene results in increased expression of CYP1A1 mRNA
CYP1A1 protein affects the metabolism of 1,8-dinitropyrene
CTD PMID:2180560, PMID:11113705, PMID:12107646, PMID:17240030 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing EXP CYP1A2 protein affects the metabolism of 1,8-dinitropyrene CTD PMID:2180560 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO 1,8-dinitropyrene results in increased expression of CYP1B1 mRNA
[CYP1B1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene
CTD PMID:11113705, PMID:21887816 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Ereg epiregulin increases expression ISO 1,8-dinitropyrene results in increased expression of EREG mRNA CTD PMID:21887816 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases response to substance
increases reduction
EXP NQO1 protein results in increased susceptibility to 1,8-dinitropyrene
NQO1 protein results in increased reduction of 1,8-dinitropyrene
CTD PMID:1774770 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene; [CYP1B1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene CTD PMID:11113705 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO 1,8-dinitropyrene results in increased expression of TIPARP mRNA CTD PMID:21887816 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation ISO 1,8-dinitropyrene results in increased phosphorylation of TRP53 protein CTD PMID:17240030 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
1-Hydroxypyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 increases secretion
multiple interactions
ISO ABCG2 protein results in increased secretion of 1-hydroxypyrene metabolite
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased secretion of 1-hydroxypyrene metabolite]
CTD PMID:24140465 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 decreases expression ISO 1-hydroxypyrene results in decreased expression of AIFM3 mRNA CTD PMID:21854004 NCBI chr11:87,364,452...87,380,705
Ensembl chr11:87,366,621...87,380,704
JBrowse link
G Ar androgen receptor multiple interactions ISO 1-hydroxypyrene binds to and results in decreased activity of AR protein; 1-hydroxypyrene inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785, PMID:27436773 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arfgap2 ADP-ribosylation factor GTPase activating protein 2 decreases expression ISO 1-hydroxypyrene results in decreased expression of ARFGAP2 mRNA CTD PMID:21854004 NCBI chr 3:80,081,541...80,093,659
Ensembl chr 3:80,081,647...80,093,658
JBrowse link
G Asxl2 ASXL transcriptional regulator 2 decreases expression ISO 1-hydroxypyrene results in decreased expression of ASXL2 mRNA CTD PMID:21854004 NCBI chr 6:27,835,346...27,919,285
Ensembl chr 6:27,887,797...27,915,563
JBrowse link
G C3 complement C3 increases expression ISO 1-hydroxypyrene results in increased expression of C3 mRNA CTD PMID:22989670 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cldn15 claudin 15 decreases expression ISO 1-hydroxypyrene results in decreased expression of CLDN15 mRNA CTD PMID:21854004 NCBI chr12:22,738,198...22,750,392
Ensembl chr12:22,738,195...22,748,860
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases secretion ISO CYP1A1 gene polymorphism results in decreased secretion of 1-hydroxypyrene CTD PMID:21787681 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dazap1 DAZ associated protein 1 decreases expression ISO 1-hydroxypyrene results in decreased expression of DAZAP1 mRNA CTD PMID:21854004 NCBI chr 7:12,289,895...12,315,897
Ensembl chr 7:12,290,402...12,311,149
JBrowse link
G E4f1 E4F transcription factor 1 decreases expression ISO 1-hydroxypyrene results in decreased expression of E4F1 mRNA CTD PMID:21854004 NCBI chr10:13,812,335...13,835,847
Ensembl chr10:13,815,293...13,826,945
JBrowse link
G Erp27 endoplasmic reticulum protein 27 decreases expression ISO 1-hydroxypyrene results in decreased expression of ERP27 mRNA CTD PMID:21854004 NCBI chr 4:170,893,946...170,912,629
Ensembl chr 4:170,893,946...170,912,629
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO 1-hydroxypyrene inhibits the reaction [ESR2 protein binds to Estradiol]
ESR2 protein binds to 1-hydroxypyrene
CTD PMID:22989670 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Faap100 FA core complex associated protein 100 decreases expression ISO 1-hydroxypyrene results in decreased expression of FAAP100 mRNA CTD PMID:21854004 NCBI chr10:109,539,381...109,552,434
Ensembl chr10:109,539,548...109,551,362
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in decreased expression of FOXP3 mRNA CTD PMID:30951957 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fst follistatin multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in increased expression of FST protein CTD PMID:31228248 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Gimap6 GTPase, IMAP family member 6 increases expression ISO 1-hydroxypyrene results in increased expression of GIMAP6 mRNA CTD PMID:21854004 NCBI chr 4:78,337,528...78,342,937
Ensembl chr 4:78,336,423...78,342,863
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases secretion ISO GSTM1 gene polymorphism results in decreased secretion of 1-hydroxypyrene CTD PMID:21787681 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases secretion ISO GSTP1 gene polymorphism results in decreased secretion of 1-hydroxypyrene CTD PMID:21787681 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Haghl hydroxyacylglutathione hydrolase-like decreases expression ISO 1-hydroxypyrene results in decreased expression of HAGHL mRNA CTD PMID:21854004 NCBI chr10:15,152,736...15,157,221
Ensembl chr10:15,152,709...15,155,412
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in increased expression of HSPB1 protein CTD PMID:31228248 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Il16 interleukin 16 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in increased expression of IL16 protein CTD PMID:31228248 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Itsn2 intersectin 2 increases expression ISO 1-hydroxypyrene results in increased expression of ITSN2 mRNA CTD PMID:21854004 NCBI chr 6:30,098,378...30,208,694
Ensembl chr 6:30,098,380...30,187,337
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO 1-hydroxypyrene results in decreased expression of JAG1 mRNA CTD PMID:22989670 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G LOC686030 hypothetical protein LOC686030 decreases expression ISO 1-hydroxypyrene results in decreased expression of C2ORF66 mRNA CTD PMID:21854004 NCBI chr 9:61,036,435...61,040,225 JBrowse link
G Lrp12 LDL receptor related protein 12 decreases expression ISO 1-hydroxypyrene results in decreased expression of LRP12 mRNA CTD PMID:21854004 NCBI chr 7:78,859,784...78,930,850
Ensembl chr 7:78,859,784...78,930,832
JBrowse link
G Myo15b myosin XVB decreases expression ISO 1-hydroxypyrene results in decreased expression of MYO15B mRNA CTD PMID:21854004 NCBI chr10:104,405,281...104,443,117 JBrowse link
G Nipal4 NIPA-like domain containing 4 increases expression ISO 1-hydroxypyrene results in increased expression of NIPAL4 mRNA CTD PMID:21854004 NCBI chr10:31,241,394...31,258,105
Ensembl chr10:31,241,394...31,258,105
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 1-hydroxypyrene results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO 1-hydroxypyrene results in increased expression of NRIP1 mRNA CTD PMID:22989670 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Pgr progesterone receptor multiple interactions ISO 1-hydroxypyrene inhibits the reaction [Progesterone binds to PGR protein]; [Progesterone co-treated with 1-hydroxypyrene] results in decreased expression of PGR mRNA CTD PMID:9144411 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phf2 PHD finger protein 2 increases expression ISO 1-hydroxypyrene results in increased expression of PHF2 mRNA CTD PMID:21854004 NCBI chr17:16,240,458...16,274,626
Ensembl chr17:16,204,427...16,274,624
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO 1-hydroxypyrene results in increased expression of PTGR1 mRNA CTD PMID:21854004 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases expression ISO 1-hydroxypyrene results in decreased expression of SLC12A7 mRNA CTD PMID:21854004 NCBI chr 1:32,086,755...32,167,950
Ensembl chr 1:32,086,755...32,141,036
JBrowse link
G Slc25a34 solute carrier family 25, member 34 decreases expression ISO 1-hydroxypyrene results in decreased expression of SLC25A34 mRNA CTD PMID:21854004 NCBI chr 5:160,175,206...160,179,978
Ensembl chr 5:160,176,124...160,179,978
JBrowse link
G Spns3 sphingolipid transporter 3 decreases expression ISO 1-hydroxypyrene results in decreased expression of SPNS3 mRNA CTD PMID:21854004 NCBI chr10:59,056,460...59,113,310
Ensembl chr10:59,057,789...59,112,788
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases activity
increases sulfation
increases metabolic processing
multiple interactions
ISO 1-hydroxypyrene results in decreased activity of SULT1A1 protein
SULT1A1 protein results in increased sulfation of 1-hydroxypyrene
SULT1A1 protein results in increased metabolism of 1-hydroxypyrene
acetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT1A1 protein]; Methanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]
CTD PMID:14570759, PMID:24140465 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases metabolic processing ISO SULT1B1 protein results in increased metabolism of 1-hydroxypyrene CTD PMID:24140465 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions
decreases activity
increases sulfation
ISO acetonitrile promotes the reaction [SULT1E1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol inhibits the reaction [SULT1E1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT1E1 protein] CTD PMID:14570759, PMID:16914110 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO Dimethylformamide inhibits the reaction [SULT2A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol inhibits the reaction [SULT2A1 protein results in increased sulfation of 1-hydroxypyrene]; Ethanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT2A1 protein] CTD PMID:14570759 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Polycyclic Aromatic Hydrocarbons results in increased abundance of 1-hydroxypyrene] which results in decreased expression of TGFB1 mRNA CTD PMID:30951957 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tmem234 transmembrane protein 234 decreases expression ISO 1-hydroxypyrene results in decreased expression of TMEM234 mRNA CTD PMID:21854004 NCBI chr 5:147,803,890...147,812,186
Ensembl chr 5:147,803,735...147,811,590
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:95,256,628...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases glucuronidation ISO UGT1A6 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 increases glucuronidation ISO UGT2A1 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:21164388 NCBI chr14:22,192,970...22,217,094 JBrowse link
G Vom1r21 vomeronasal 1 receptor 21 decreases expression ISO 1-hydroxypyrene results in decreased expression of VN1R4 mRNA CTD PMID:21854004 NCBI chr19:28,377,249...28,378,118
Ensembl chr19:28,377,249...28,378,118
JBrowse link
G Zfp335 zinc finger protein 335 decreases expression ISO 1-hydroxypyrene results in decreased expression of ZNF335 mRNA CTD PMID:21854004 NCBI chr 3:161,357,201...161,378,073
Ensembl chr 3:161,357,278...161,376,119
JBrowse link
4-Nitropyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO [Particulate Matter results in increased abundance of 4-nitropyrene] which results in increased secretion of TNF protein CTD PMID:32007923 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Benzo[a]pyrene-7,8-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
increases expression
increases export
ISO [ABCC4 protein results in increased export of benzo(a)pyrene 7,8-dihydrodiol] which results in decreased chemical synthesis of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of ABCC4 mRNA; benzo(a)pyrene 7,8-dihydrodiol results in increased expression of ABCC4 protein
CTD PMID:22155354 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 multiple interactions
decreases response to substance
ISO [AKR1A1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol; AKR1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol; NAD promotes the reaction [AKR1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]; NADP promotes the reaction [AKR1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]; ponalrestat inhibits the reaction [AKR1A1 protein results in decreased susceptibility to benzo(a)pyrene 7,8-dihydrodiol] CTD PMID:15720144, PMID:21910479, PMID:22053912 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO [AKR1B1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions ISO [AKR1B10 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions ISO [AKR1C4 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 multiple interactions ISO [AKR1C2 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21910479 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression
increases phosphorylation
ISO benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BAD protein
benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of BAD protein
CTD PMID:15698582 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BCL2L1 protein CTD PMID:15698582 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BID protein CTD PMID:15698582 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
increases chemical synthesis
ISO
EXP
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1A1 mRNA
[CYP1A1 protein results in increased metabolism of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol
[[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol
[Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] which results in increased secretion of benzo(a)pyrene 7,8-dihydrodiol; benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; CYP1A1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol; CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]; GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]]; hyperforin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; hypericin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; Medroxyprogesterone Acetate inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1A1 mRNA]; pseudohypericin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; Quercetin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]; Ursodeoxycholic Acid inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol
CTD PMID:2154339, PMID:10706104, PMID:14633740, PMID:15720144, PMID:17525473, PMID:19879933, PMID:21028851, PMID:24530354, PMID:32227843 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
affects metabolic processing
increases chemical synthesis
increases oxidation
multiple interactions
ISO
EXP
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1B1 mRNA
CYP1B1 affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol
CYP1B1 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol
CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol
benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; bergamottin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol; imperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; isoimperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; isopimpinellin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]; NADP promotes the reaction [CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]
CTD PMID:15720144, PMID:15861043, PMID:19879933, PMID:21028851, PMID:24025706 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO [[CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] which results in increased abundance of benzo(a)pyrene-7,8,9,10-tetrol; [[CYP2S1 protein co-treated with Hydrogen Peroxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] which results in increased abundance of benzo(a)pyrene-7,8,9,10-tetrol; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:19713358 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:24530354 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP benzo(a)pyrene 7,8-dihydrodiol results in increased expression of GSTA1 mRNA CTD PMID:11008122 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]] CTD PMID:17525473 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]; GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]] CTD PMID:17525473 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO benzo(a)pyrene 7,8-dihydrodiol results in increased expression of HRAS mRNA CTD PMID:11008122 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of MAPK14 protein CTD PMID:15698582 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of MAPK8 protein CTD PMID:15698582, PMID:22053912 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO
EXP
benzo(a)pyrene 7,8-dihydrodiol results in increased expression of NQO1 mRNA CTD PMID:11008122 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [benzo(a)pyrene 7,8-dihydrodiol binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; benzo(a)pyrene 7,8-dihydrodiol binds to and results in increased activity of NR1I2 protein CTD PMID:23845848 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased cleavage of PARP1 protein] CTD PMID:15572374 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:24530354 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases metabolic processing ISO PTGS1 protein results in increased metabolism of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:11159734 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases metabolic processing ISO PTGS2 protein results in increased metabolism of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:11159734 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP TNF protein inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene 7,8-dihydrodiol] CTD PMID:24025706 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases chemical synthesis
ISO [TP53 protein results in increased susceptibility to Etoposide] which results in decreased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol; benzo(a)pyrene 7,8-dihydrodiol results in increased expression of and results in increased phosphorylation of TP53 protein; Etoposide promotes the reaction [TP53 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol] CTD PMID:15698582, PMID:29471073 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 increases glucuronidation ISO UGT2A1 protein results in increased glucuronidation of benzo(a)pyrene 7,8-dihydrodiol CTD PMID:21164388 NCBI chr14:22,192,970...22,217,094 JBrowse link
benzo[a]pyrene-7,8-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions
ISO benzo(a)pyrene-7,8-dione affects the localization of AHR protein
AHR protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA]
CTD PMID:10706104 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases chemical synthesis
multiple interactions
affects chemical synthesis
increases expression
ISO AKR1A1 protein results in increased chemical synthesis of benzo(a)pyrene-7,8-dione
[AKR1A1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione; AKR1A1 protein results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione; NAD promotes the reaction [AKR1A1 protein affects the chemical synthesis of benzo(a)pyrene-7,8-dione]
benzo(a)pyrene-7,8-dione results in increased expression of AKR1A1 mRNA
CTD PMID:9973208, PMID:15720144, PMID:16411658, PMID:21910479 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO [AKR1B1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions ISO [AKR1B10 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions ISO [AKR1C4 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 multiple interactions ISO [AKR1C2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 multiple interactions ISO [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione] which results in decreased abundance of Oxygen; [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione] which results in increased chemical synthesis of Hydrogen Peroxide; [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione] which results in increased chemical synthesis of Superoxides; [AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions ISO [AKR7A3 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione CTD PMID:21910479 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA] CTD PMID:10706104 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO AHR protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA]; ARNT protein affects the reaction [benzo(a)pyrene-7,8-dione results in increased expression of CYP1A1 mRNA] CTD PMID:9973208, PMID:10706104 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO benzo(a)pyrene-7,8-dione results in increased expression of and results in increased activity of CYP1B1 protein
benzo(a)pyrene-7,8-dione results in increased expression of CYP1B1 mRNA
CTD PMID:16411658 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]; Ascorbic Acid inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]
benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 mRNA; benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein
CTD PMID:22053912 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO benzo(a)pyrene-7,8-dione results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:12213569 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO benzo(a)pyrene-7,8-dione results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:12213569 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO benzo(a)pyrene-7,8-dione results in increased expression of NQO1 mRNA; benzo(a)pyrene-7,8-dione results in increased expression of NQO1 protein
[NQO1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione
CTD PMID:21910479, PMID:22053912 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases metabolic processing ISO SULT1A1 protein results in increased metabolism of benzo(a)pyrene-7,8-dione CTD PMID:22782890 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 increases metabolic processing ISO SULT1E1 protein results in increased metabolism of benzo(a)pyrene-7,8-dione CTD PMID:22782890 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
Benzo[a]pyrene-7,8-oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7,8-oxide] CTD PMID:12051674 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7,8-oxide] CTD PMID:12051674 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
Cyclopenta[cd]pyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP cyclopenta(c,d)pyrene binds to and results in increased activity of AHR protein CTD PMID:11525907 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO cyclopenta(c,d)pyrene results in increased mutagenesis of KRAS gene CTD PMID:9659573 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
Indeno[1,2,3-cd]pyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ABCC5 mRNA CTD PMID:32251684 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ACSM3 mRNA CTD PMID:26377693 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADAMTS15 mRNA CTD PMID:26377693 NCBI chr 8:31,977,001...32,000,378
Ensembl chr 8:31,977,001...32,000,378
JBrowse link
G Adig adipogenin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADIG mRNA CTD PMID:26377693 NCBI chr 3:153,946,828...153,952,269
Ensembl chr 3:153,949,215...153,952,108
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADIPOQ mRNA CTD PMID:26377693 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ADORA1 mRNA CTD PMID:32251684 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO
EXP
[benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [indeno(1,2,3-cd)pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene] promotes the reaction [pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with pyrene] promotes the reaction [fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [chrysene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(k)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(j)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; [Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benz(a)anthracene results in increased activity of AHR protein]; indeno(1,2,3-cd)pyrene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]
indeno(1,2,3-cd)pyrene binds to and results in increased activity of AHR protein
CTD PMID:11525907, PMID:12371477, PMID:12850102, PMID:17665671, PMID:21781905, PMID:25500124 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AHRR mRNA CTD PMID:32251684 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ALDH1A2 mRNA CTD PMID:26377693 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ALDH1A3 mRNA CTD PMID:32251684 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ALDH3A1 mRNA CTD PMID:32251684 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Amer2 APC membrane recruitment protein 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of AMER2 mRNA CTD PMID:32251684 NCBI chr15:40,663,183...40,667,705
Ensembl chr15:40,665,041...40,667,173
JBrowse link
G Amy1a amylase, alpha 1A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of AMY1 mRNA CTD PMID:26377693 NCBI chr 2:216,428,709...216,443,518
Ensembl chr 2:216,428,709...216,443,518
JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ANGPTL4 mRNA CTD PMID:26377693 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Areg amphiregulin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of AREG mRNA CTD PMID:26377693 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ARL4D mRNA CTD PMID:26377693 NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ARNTL mRNA CTD PMID:26377693 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ASGR2 mRNA CTD PMID:26377693 NCBI chr10:56,710,446...56,723,608
Ensembl chr10:56,710,464...56,723,611
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of ATOH8 mRNA CTD PMID:32251684 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BAIAP2L1 mRNA CTD PMID:26377693 NCBI chr12:12,226,967...12,321,172
Ensembl chr12:12,227,010...12,321,172
JBrowse link
G Bche butyrylcholinesterase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BCHE mRNA CTD PMID:26377693 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BCL6 mRNA CTD PMID:26377693 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bnc1 basonuclin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BNC1 mRNA CTD PMID:26377693 NCBI chr 1:143,793,280...143,818,748
NCBI chr 1:143,869,440...143,878,077
Ensembl chr 1:143,793,064...143,818,706
JBrowse link
G Bpifa1 BPI fold containing family A, member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of BPIFA1 mRNA CTD PMID:26377693 NCBI chr 3:149,624,867...149,630,610
Ensembl chr 3:149,624,712...149,630,613
JBrowse link
G C2 complement C2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of C2 mRNA CTD PMID:26377693 NCBI chr20:4,542,340...4,561,152
Ensembl chr20:4,542,340...4,561,152
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CAR14 mRNA CTD PMID:26377693 NCBI chr 2:198,010,142...198,017,635
Ensembl chr 2:198,010,349...198,016,898
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CAR3 mRNA CTD PMID:26377693 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Cacybp calcyclin binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CACYBP mRNA CTD PMID:26377693 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CADM1 mRNA CTD PMID:21635667 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCDC80 mRNA CTD PMID:26377693 NCBI chr11:60,645,660...60,679,249
Ensembl chr11:60,645,086...60,679,555
JBrowse link
G Ccdc85a coiled-coil domain containing 85A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCDC85A mRNA CTD PMID:26377693 NCBI chr14:112,719,482...112,900,724
Ensembl chr14:112,719,482...112,946,875
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCNA2 mRNA CTD PMID:32251684 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccng2 cyclin G2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CCNG2 mRNA CTD PMID:32251684 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccnjl cyclin J-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CCNJL mRNA CTD PMID:26377693 NCBI chr10:29,122,713...29,181,610
Ensembl chr10:29,123,273...29,182,568
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CEBPB mRNA CTD PMID:32251684 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CEBPD mRNA CTD PMID:26377693 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CELSR2 mRNA CTD PMID:21635667, PMID:32251684 NCBI chr 2:211,183,410...211,207,458
Ensembl chr 2:211,183,311...211,207,465
JBrowse link
G Cenpa centromere protein A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CENPA mRNA CTD PMID:32251684 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cfd complement factor D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CFD mRNA CTD PMID:26377693 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CHORDC1 mRNA CTD PMID:26377693 NCBI chr 8:17,421,552...17,445,513
Ensembl chr 8:17,421,557...17,446,165
JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CIDEA mRNA CTD PMID:26377693 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CKMT2 mRNA CTD PMID:26377693 NCBI chr 2:21,422,680...21,452,797
Ensembl chr 2:21,422,818...21,437,193
JBrowse link
G Cldn17 claudin 17 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLDN17 mRNA CTD PMID:21635667 NCBI chr11:28,477,184...28,478,360
Ensembl chr11:28,477,184...28,478,360
JBrowse link
G Clec10a C-type lectin domain containing 10A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLEC10A mRNA CTD PMID:26377693 NCBI chr10:56,764,927...56,769,447
Ensembl chr10:56,764,927...56,769,457
JBrowse link
G Clec9a C-type lectin domain containing 9A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLEC9A mRNA CTD PMID:26377693 NCBI chr 4:163,173,593...163,189,532
Ensembl chr 4:163,174,487...163,189,530
JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CLIC4 mRNA CTD PMID:26377693 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COL2A1 mRNA CTD PMID:21635667 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Col4a6 collagen type IV alpha 6 chain decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COL4A6 mRNA CTD PMID:21635667 NCBI chr  X:112,405,647...112,768,337
Ensembl chr  X:112,405,647...112,473,822
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of COX7A1 mRNA CTD PMID:26377693 NCBI chr 1:88,619,619...88,650,672
Ensembl chr 1:91,071,493...91,074,294
Ensembl chr 1:91,071,493...91,074,294
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CREB1 mRNA CTD PMID:32251684 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CSRP3 mRNA CTD PMID:26377693 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Ctsb cathepsin B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CTSB mRNA CTD PMID:32251684 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CTSD mRNA CTD PMID:32251684 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of CXCL12 mRNA CTD PMID:32251684 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO
EXP
Dexamethasone inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 protein]; indeno(1,2,3-cd)pyrene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]
indeno(1,2,3-cd)pyrene results in increased activity of CYP1A1 protein
indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of CYP1A1 protein
CTD PMID:10190573, PMID:17253728, PMID:19463884, PMID:21781905, PMID:26377693, PMID:27196671, PMID:32251684 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CYP1A2 mRNA CTD PMID:17253728 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 mRNA CTD PMID:17253728, PMID:27196671 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of DDIT4 mRNA CTD PMID:32251684 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DGAT2 mRNA CTD PMID:26377693 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DNAJA1 mRNA CTD PMID:26377693 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dpt dermatopontin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DPT mRNA CTD PMID:26377693 NCBI chr13:83,073,307...83,102,404
Ensembl chr13:83,073,544...83,102,401
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DVL3 mRNA CTD PMID:26377693 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of DYNLL1 mRNA CTD PMID:26377693 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of EFEMP1 mRNA CTD PMID:26377693 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ELOVL6 mRNA CTD PMID:26377693 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Ephb6 Eph receptor B6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of EPHB6 mRNA CTD PMID:26377693 NCBI chr 4:70,903,253...70,918,514
Ensembl chr 4:70,903,253...70,918,514
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ERBB2 mRNA CTD PMID:21635667 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ERRFI1 mRNA CTD PMID:26377693 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO indeno(1,2,3-cd)pyrene binds to ESR1 protein CTD PMID:32251684 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA] CTD PMID:21635667 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FABP4 mRNA CTD PMID:26377693 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fam181b family with sequence similarity 181, member B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FAM181B mRNA CTD PMID:26377693 NCBI chr 1:157,920,786...157,922,283
Ensembl chr 1:157,920,786...157,922,274
JBrowse link
G Fibin fin bud initiation factor homolog decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FIBIN mRNA CTD PMID:26377693 NCBI chr 3:101,545,207...101,547,478
Ensembl chr 3:101,545,208...101,547,478
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FOS mRNA CTD PMID:32251684 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Frem1 Fras1 related extracellular matrix 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of FREM1 mRNA CTD PMID:21635667 NCBI chr 5:101,018,009...101,166,794
Ensembl chr 5:101,020,448...101,166,651
JBrowse link
G Fsbp fibrinogen silencer binding protein increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of FSBP mRNA CTD PMID:32251684 NCBI chr 5:25,167,350...25,173,138
Ensembl chr 5:25,168,295...25,172,939
JBrowse link
G Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GDPD2 mRNA CTD PMID:26377693 NCBI chr  X:70,563,381...70,572,295
Ensembl chr  X:70,563,570...70,572,295
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GFPT2 mRNA CTD PMID:26377693 NCBI chr10:35,279,237...35,325,506
Ensembl chr10:35,279,236...35,325,508
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of GJB2 mRNA CTD PMID:32251684 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Golph3l golgi phosphoprotein 3-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GOLPH3L mRNA CTD PMID:26377693 NCBI chr 2:197,720,259...197,749,060
Ensembl chr 2:197,715,761...197,750,115
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GPD1 mRNA CTD PMID:26377693 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GPM6A mRNA CTD PMID:26377693 NCBI chr16:39,367,697...39,719,292
Ensembl chr16:39,367,692...39,719,187
JBrowse link
G Grifin galectin-related inter-fiber protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GRIFIN mRNA CTD PMID:26377693 NCBI chr12:16,170,108...16,172,144
Ensembl chr12:16,170,162...16,172,129
JBrowse link
G Grp gastrin releasing peptide decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GRP mRNA CTD PMID:26377693 NCBI chr18:61,563,458...61,576,818
Ensembl chr18:61,563,053...61,576,818
JBrowse link
G Gxylt2 glucoside xylosyltransferase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GXYLT2 mRNA CTD PMID:26377693 NCBI chr 4:133,179,185...133,263,493
Ensembl chr 4:133,179,309...133,262,841
JBrowse link
G Gzma granzyme A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of GZMA mRNA CTD PMID:26377693 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Has1 hyaluronan synthase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HAS1 mRNA CTD PMID:26377693 NCBI chr 1:59,720,612...59,732,409
Ensembl chr 1:59,720,612...59,732,409
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of HMOX1 mRNA CTD PMID:32251684 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrc histidine rich calcium binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HRC mRNA CTD PMID:26377693 NCBI chr 1:101,324,788...101,328,391
Ensembl chr 1:101,324,652...101,328,435
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSP90AA1 mRNA CTD PMID:26377693 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPA1A mRNA CTD PMID:26377693 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPA8 mRNA CTD PMID:26377693 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPD1 mRNA CTD PMID:26377693 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of HSPH1 mRNA CTD PMID:26377693 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Ier3 immediate early response 3 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IER3 mRNA CTD PMID:22579512, PMID:32251684 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of IGF1R mRNA CTD PMID:32251684 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IGFBP5 mRNA CTD PMID:26377693 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IQSEC1 mRNA CTD PMID:26377693 NCBI chr 4:123,400,717...123,454,656
Ensembl chr 4:123,307,624...123,453,478
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of IRF2BP2 mRNA CTD PMID:26377693 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA] CTD PMID:21635667 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itga6 integrin subunit alpha 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ITGA6 mRNA CTD PMID:26377693 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Itgb6 integrin subunit beta 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ITGB6 mRNA CTD PMID:26377693 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of JCHAIN mRNA CTD PMID:26377693 NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA] CTD PMID:21635667 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kdm1b lysine demethylase 1B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KDM1B mRNA CTD PMID:26377693 NCBI chr17:17,987,972...18,028,808
Ensembl chr17:17,987,972...18,028,808
JBrowse link
G Kitlg KIT ligand decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KITL mRNA CTD PMID:26377693 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klhl23 kelch-like family member 23 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PHOSPHO2-KLHL23 mRNA CTD PMID:32251684 NCBI chr 3:56,056,957...56,070,614
Ensembl chr 3:56,056,925...56,070,614
JBrowse link
G Klk1 kallikrein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KLK1 mRNA CTD PMID:26377693 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KNSTRN mRNA CTD PMID:26377693 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Krt19 keratin 19 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of KRT19 mRNA CTD PMID:32251684 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Lgals1 galectin 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of LGALS1 mRNA CTD PMID:22579512 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LONRF3 mRNA CTD PMID:26377693 NCBI chr  X:122,937,987...122,973,289
Ensembl chr  X:122,938,009...122,973,321
JBrowse link
G Lpin2 lipin 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LPIN2 mRNA CTD PMID:26377693 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of LRRN4 mRNA CTD PMID:26377693 NCBI chr 3:125,521,879...125,547,685
Ensembl chr 3:125,523,781...125,533,600
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
multiple interactions
ISO indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein
Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]
CTD PMID:21635667 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mb myoglobin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MB mRNA CTD PMID:26377693 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of MDM2 mRNA CTD PMID:32251684 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mef2b myocyte enhancer factor 2B increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of MEF2B mRNA CTD PMID:32251684 NCBI chr16:21,001,204...21,017,651
Ensembl chr16:21,001,206...21,017,163
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MFAP2 mRNA CTD PMID:26377693 NCBI chr 5:159,534,202...159,539,750
Ensembl chr 5:159,534,202...159,539,750
JBrowse link
G Mgat1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MGAT1 mRNA CTD PMID:26377693 NCBI chr10:34,518,392...34,537,214
Ensembl chr10:34,519,790...34,537,210
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA] CTD PMID:21635667 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MMP3 mRNA CTD PMID:26377693 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MNDA mRNA CTD PMID:26377693 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
JBrowse link
G Mpp6 membrane palmitoylated protein 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MPP6 mRNA CTD PMID:26377693 NCBI chr 4:79,846,506...79,928,977
Ensembl chr 4:79,846,521...79,926,703
JBrowse link
G Mrap melanocortin 2 receptor accessory protein decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MRAP mRNA CTD PMID:26377693 NCBI chr11:30,904,733...30,915,225
Ensembl chr11:30,904,733...30,915,225
JBrowse link
G Msln mesothelin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MSLN mRNA CTD PMID:26377693 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MTARC1 mRNA CTD PMID:26377693 NCBI chr13:102,693,679...102,724,120
Ensembl chr13:102,698,546...102,721,218
JBrowse link
G Muc16 mucin 16, cell surface associated decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MUC16 mRNA CTD PMID:26377693 NCBI chr 8:18,438,838...18,639,777 JBrowse link
G Mybpc3 myosin binding protein C3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYBPC3 mRNA CTD PMID:26377693 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYH6 mRNA CTD PMID:26377693 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myl1 myosin, light chain 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL1 mRNA CTD PMID:26377693 NCBI chr 9:73,937,820...73,958,480
Ensembl chr 9:73,937,823...73,958,480
JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL4 mRNA CTD PMID:26377693 NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100
JBrowse link
G Myl7 myosin light chain 7 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYL7 mRNA CTD PMID:26377693 NCBI chr14:86,144,770...86,147,075
Ensembl chr14:86,143,862...86,147,553
JBrowse link
G Mylk myosin light chain kinase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of MYLK mRNA CTD PMID:21635667 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NDC80 mRNA CTD PMID:22579512 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NEDD4 mRNA CTD PMID:26377693 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of NFIL3 mRNA CTD PMID:26377693 NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of NQO1 mRNA CTD PMID:17253728 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of OASL1 mRNA CTD PMID:26377693 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
JBrowse link
G Otop1 otopetrin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of OTOP1 mRNA CTD PMID:26377693 NCBI chr14:77,236,278...77,263,729
Ensembl chr14:77,236,278...77,263,729
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PAH mRNA CTD PMID:22579512 NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO indeno(1,2,3-cd)pyrene results in increased cleavage of PARP1 protein CTD PMID:21132278 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PBX1 mRNA CTD PMID:26377693 NCBI chr13:86,390,741...86,671,460
Ensembl chr13:86,390,741...86,451,002
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PCK1 mRNA CTD PMID:26377693 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pde5a phosphodiesterase 5A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDE5A mRNA CTD PMID:26377693 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDK4 mRNA CTD PMID:26377693 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdzd2 PDZ domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PDZD2 mRNA CTD PMID:26377693 NCBI chr 2:62,399,748...62,520,448
Ensembl chr 2:62,399,748...62,634,785
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PEBP1 mRNA CTD PMID:26377693 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Penk proenkephalin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PENK mRNA CTD PMID:26377693 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pgam2 phosphoglycerate mutase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGAM2 mRNA CTD PMID:26377693 NCBI chr14:86,045,005...86,047,116
Ensembl chr14:86,044,969...86,047,162
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGAP2 mRNA CTD PMID:26377693 NCBI chr 1:167,309,021...167,335,550
Ensembl chr 1:167,309,051...167,334,741
JBrowse link
G Pgr progesterone receptor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PGR mRNA CTD PMID:32251684 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phf19 PHD finger protein 19 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PHF19 mRNA CTD PMID:32251684 NCBI chr 3:13,957,136...13,978,283
Ensembl chr 3:13,957,136...13,978,224
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PKIB mRNA CTD PMID:32251684 NCBI chr20:40,616,868...40,712,598
Ensembl chr20:40,618,128...40,712,592
JBrowse link
G Plin1 perilipin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PLIN1 mRNA CTD PMID:26377693 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Plin4 perilipin 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PLIN4 mRNA CTD PMID:26377693 NCBI chr 9:10,963,494...10,972,360
Ensembl chr 9:10,963,723...10,971,277
JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of POLR1B mRNA CTD PMID:26377693 NCBI chr 3:121,632,043...121,656,506
Ensembl chr 3:121,632,043...121,656,506
JBrowse link
G Popdc2 popeye domain containing 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of POPDC2 mRNA CTD PMID:26377693 NCBI chr11:64,915,041...64,954,704
Ensembl chr11:64,936,692...64,952,687
JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of PPP4R3B mRNA CTD PMID:26377693 NCBI chr14:113,570,150...113,618,138
Ensembl chr14:113,570,150...113,618,138
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RARA mRNA CTD PMID:32251684 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Reln reelin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RELN mRNA CTD PMID:21635667 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Ret ret proto-oncogene decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RET mRNA CTD PMID:32251684 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Retn resistin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RETN mRNA CTD PMID:26377693 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Rhoc ras homolog family member C increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RHOC mRNA CTD PMID:22579512 NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RORA mRNA CTD PMID:26377693 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rprml reprimo-like decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RPRML mRNA CTD PMID:26377693 NCBI chr10:91,710,495...91,711,499
Ensembl chr10:91,710,495...91,711,499
JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of RSRP1 mRNA CTD PMID:26377693 NCBI chr 5:153,260,930...153,264,669
Ensembl chr 5:153,260,930...153,264,669
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of RUNX2 mRNA CTD PMID:32251684 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sbsn suprabasin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SBSN mRNA CTD PMID:26377693 NCBI chr 1:89,202,527...89,206,994
Ensembl chr 1:89,202,527...89,206,994
JBrowse link
G Sdcbp2 syndecan binding protein 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SDCBP2 mRNA CTD PMID:26377693 NCBI chr 3:147,073,160...147,101,917
Ensembl chr 3:147,073,160...147,101,911
JBrowse link
G Sema3b semaphorin 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SEMA3B mRNA CTD PMID:32251684 NCBI chr 8:116,353,791...116,362,655
Ensembl chr 8:116,354,073...116,361,343
JBrowse link
G Septin3 septin 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SEPTIN3 mRNA CTD PMID:26377693 NCBI chr 7:123,506,535...123,526,542
Ensembl chr 7:123,510,804...123,526,542
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SGK1 mRNA CTD PMID:32251684 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Shc3 SHC adaptor protein 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SHC3 mRNA CTD PMID:21635667 NCBI chr17:13,670,520...13,791,043
Ensembl chr17:13,670,520...13,791,043
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SIAH2 mRNA CTD PMID:32251684 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Slc10a6 solute carrier family 10 member 6 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC10A6 mRNA CTD PMID:26377693 NCBI chr14:7,618,022...7,682,377
Ensembl chr14:7,618,022...7,682,377
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC1A5 mRNA CTD PMID:26377693 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC2A4 mRNA CTD PMID:26377693 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC2A5 mRNA CTD PMID:26377693 NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
JBrowse link
G Slc5a12 solute carrier family 5 member 12 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC5A12 mRNA CTD PMID:26377693 NCBI chr 3:101,791,336...101,833,044
Ensembl chr 3:101,791,337...101,833,044
JBrowse link
G Slc5a3 solute carrier family 5 member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLC5A3 mRNA CTD PMID:26377693 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of SLC7A11 mRNA CTD PMID:32251684 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of SLC7A5 mRNA CTD PMID:32251684 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Sln sarcolipin decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SLN mRNA CTD PMID:26377693 NCBI chr 8:58,431,407...58,435,654
Ensembl chr 8:58,431,407...58,435,654
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SMPD3 mRNA CTD PMID:26377693 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA] CTD PMID:21635667 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SOX17 mRNA CTD PMID:26377693 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of STC2 mRNA CTD PMID:32251684 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of STIP1 mRNA CTD PMID:26377693 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SULF1 mRNA CTD PMID:26377693 NCBI chr 5:5,999,520...6,186,901
Ensembl chr 5:5,999,475...6,186,329
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SULT1A1 mRNA CTD PMID:26377693 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Syt1 synaptotagmin 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of SYT1 mRNA CTD PMID:26377693 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
G Tfap2c transcription factor AP-2 gamma decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFAP2C mRNA CTD PMID:32251684 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194
JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFF1 mRNA CTD PMID:32251684 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tff3 trefoil factor 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TFF3 mRNA CTD PMID:26377693 NCBI chr20:9,850,800...9,855,481
Ensembl chr20:9,850,803...9,855,481
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of THRSP mRNA CTD PMID:26377693 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
decreases expression
ISO indeno(1,2,3-cd)pyrene results in increased expression of TIMP1 mRNA
indeno(1,2,3-cd)pyrene results in decreased expression of TIMP1 mRNA
CTD PMID:22579512, PMID:26377693 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tln2 talin 2 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TLN2 mRNA CTD PMID:21635667 NCBI chr 8:73,009,980...73,441,536
Ensembl chr 8:73,014,137...73,194,837
JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEFF1 mRNA CTD PMID:32251684 NCBI chr 5:64,326,733...64,412,531
Ensembl chr 5:64,326,733...64,412,523
JBrowse link
G Tmem245 transmembrane protein 245 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEM245 mRNA CTD PMID:26377693 NCBI chr 5:73,909,032...73,986,602
Ensembl chr 5:73,918,747...73,986,373
JBrowse link
G Tmem45b transmembrane protein 45b decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TMEM45B mRNA CTD PMID:26377693 NCBI chr 8:32,563,872...32,609,212
Ensembl chr 8:32,563,874...32,609,212
JBrowse link
G Tnni3 troponin I3, cardiac type decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TNNI3 mRNA CTD PMID:26377693 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TNNT2 mRNA CTD PMID:26377693 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TRPV4 mRNA CTD PMID:26377693 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of TSC22D3 mRNA CTD PMID:26377693 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tspear thrombospondin-type laminin G domain and EAR repeats increases expression ISO indeno(1,2,3-cd)pyrene results in increased expression of TSPEAR mRNA CTD PMID:32251684 NCBI chr20:11,501,510...11,529,210
Ensembl chr20:11,501,925...11,528,332
JBrowse link
G Ucp1 uncoupling protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of UCP1 mRNA CTD PMID:26377693 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Upk3b uroplakin 3B decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of UPK3B mRNA CTD PMID:26377693 NCBI chr12:23,676,169...23,682,395
Ensembl chr12:23,676,152...23,682,381
JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of VAV3 mRNA CTD PMID:21635667 NCBI chr 2:212,247,061...212,585,818
Ensembl chr 2:212,247,451...212,585,818
JBrowse link
G Wdr62 WD repeat domain 62 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of WDR62 mRNA CTD PMID:26377693 NCBI chr 1:90,995,545...91,034,592
Ensembl chr 1:88,694,824...88,734,223
JBrowse link
G Wdr92 WD repeat domain 92 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of WDR92 mRNA CTD PMID:26377693 NCBI chr14:100,373,129...100,394,143
Ensembl chr14:100,373,129...100,394,145
JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of WT1 mRNA CTD PMID:26377693 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of XBP1 mRNA CTD PMID:32251684 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Zdhhc22 zinc finger DHHC-type palmitoyltransferase 22 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ZDHHC22 mRNA CTD PMID:26377693 NCBI chr 6:111,008,440...111,015,695
Ensembl chr 6:111,007,674...111,015,598
JBrowse link
G Zfp628 zinc finger protein 628 decreases expression ISO indeno(1,2,3-cd)pyrene results in decreased expression of ZFP628 mRNA CTD PMID:26377693 NCBI chr 1:72,465,403...72,474,442
Ensembl chr 1:72,465,341...72,468,738
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      group 19728
        polyatomic entity 19727
          molecule 19554
            cyclic compound 19359
              organic cyclic compound 19320
                organic polycyclic compound 16395
                  pyrenes 296
                    1,3-Dinitropyrene 13
                    1,6-Dihydroxypyrene 0
                    1,6-Dimethoxypyrene 0
                    1,6-Dinitropyrene 3
                    1,8-Dihydroxypyrene 0
                    1,8-Dinitropyrene 10
                    1-Hydroxy-6-methoxypyrene 0
                    1-Hydroxypyrene 50
                    1-Methoxypyrene 0
                    1-Pyrenylsulfate 0
                    10-Oxabenzo[def]chrysen-9-one 0
                    2-(2-pyrenyl)acetonitrile 0
                    2-Hydroxypyrene 0
                    2-Nitropyrene 0
                    4,5-Dihydroxypyrene 0
                    4-Nitropyrene 1
                    Acepyrene 0
                    Benzo[a]pyrene-7,8-diol 29
                    Benzo[a]pyrene-7,8-oxide 2
                    Benzo[a]pyrene-9,10-oxide 0
                    Benzo[a]pyrene-cis-9,10-dihydrodiol 0
                    Cyclopenta[cd]pyrene 2
                    Indeno[1,2,3-cd]pyrene 215
                    Pyrene-1,6-dione 0
                    Pyrene-1,8-dione 0
                    Pyrene-4,5-dione 0
                    benzo[a]pyrene-7,8-dione 18
                    benzo[a]pyrene-cis-7,8-dihydrodiol + 18
                    cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate 0
                    cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      p-block molecular entity 19702
                        carbon group molecular entity 19608
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic polycyclic compound 16395
                                  pyrenes 296
                                    1,3-Dinitropyrene 13
                                    1,6-Dihydroxypyrene 0
                                    1,6-Dimethoxypyrene 0
                                    1,6-Dinitropyrene 3
                                    1,8-Dihydroxypyrene 0
                                    1,8-Dinitropyrene 10
                                    1-Hydroxy-6-methoxypyrene 0
                                    1-Hydroxypyrene 50
                                    1-Methoxypyrene 0
                                    1-Pyrenylsulfate 0
                                    10-Oxabenzo[def]chrysen-9-one 0
                                    2-(2-pyrenyl)acetonitrile 0
                                    2-Hydroxypyrene 0
                                    2-Nitropyrene 0
                                    4,5-Dihydroxypyrene 0
                                    4-Nitropyrene 1
                                    Acepyrene 0
                                    Benzo[a]pyrene-7,8-diol 29
                                    Benzo[a]pyrene-7,8-oxide 2
                                    Benzo[a]pyrene-9,10-oxide 0
                                    Benzo[a]pyrene-cis-9,10-dihydrodiol 0
                                    Cyclopenta[cd]pyrene 2
                                    Indeno[1,2,3-cd]pyrene 215
                                    Pyrene-1,6-dione 0
                                    Pyrene-1,8-dione 0
                                    Pyrene-4,5-dione 0
                                    benzo[a]pyrene-7,8-dione 18
                                    benzo[a]pyrene-cis-7,8-dihydrodiol + 18
                                    cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate 0
                                    cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.