Benzo[k]fluoranthene - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	Benzo[k]fluoranthene	go back to main search page
Accession:	CHEBI:34569	browse the term
Definition:	A naphthalene that has formula C20H12.
Synonyms:	related_synonym:	11,12-Benzofluoranthene; Formula=C20H12; InChI=1S/C20H12/c1-2-6-15-12-19-17-10-4-8-13-7-3-9-16(20(13)17)18(19)11-14(15)5-1/h1-12H; InChIKey=HAXBIWFMXWRORI-UHFFFAOYSA-N; SMILES=c1ccc2cc-3c(cc2c1)-c1cccc2cccc-3c12
	xref:	CAS:207-08-9; KEGG:C14321
	xref_mesh:	MESH:C022921

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Genes (624)

Benzo[k]fluoranthene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase like 3

decreases expression

benzo(k)fluoranthene results in decreased expression of AADACL3 mRNA

NCBI chr 1:12,716,110...12,728,760
Ensembl chr 1:12,716,110...12,728,760

G

apoptosis associated tyrosine kinase

increases expression

benzo(k)fluoranthene results in increased expression of AATK mRNA

NCBI chr17:81,117,295...81,166,221
Ensembl chr17:81,110,487...81,166,221

G

ATP binding cassette subfamily A member 12

decreases expression

benzo(k)fluoranthene results in decreased expression of ABCA12 mRNA

NCBI chr 2:214,931,542...215,138,626
Ensembl chr 2:214,931,542...215,138,626

G

ATP binding cassette subfamily B member 1

increases expression
decreases expression

benzo(k)fluoranthene results in increased expression of ABCB1 mRNA
benzo(k)fluoranthene results in decreased expression of ABCB1A mRNA

PMID:15566942 PMID:26377693

NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323

G

ATP binding cassette subfamily G member 2 (JR blood group)

increases expression
multiple interactions

benzo(k)fluoranthene results in increased expression of ABCG2 mRNA; benzo(k)fluoranthene results in increased expression of ABCG2 protein
AHR protein promotes the reaction [benzo(k)fluoranthene results in increased expression of ABCG2 protein]; benzo(k)fluoranthene promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]; benzo(k)fluoranthene results in increased expression of and results in increased activity of ABCG2 protein

PMID:15917307 PMID:17077187

NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628

G

abhydrolase domain containing 12B

decreases expression

benzo(k)fluoranthene results in decreased expression of ABHD12B mRNA

NCBI chr14:50,872,053...50,904,970
Ensembl chr14:50,872,053...50,904,970

G

actin binding LIM protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ABLIM1 mRNA

NCBI chr10:114,431,110...114,801,373
Ensembl chr10:114,431,110...114,768,061

G

acyl-CoA binding domain containing 5

decreases expression

benzo(k)fluoranthene results in decreased expression of ACBD5 mRNA

NCBI chr10:27,182,838...27,242,111
Ensembl chr10:27,168,135...27,243,046

G

angiotensin converting enzyme 2

decreases expression

benzo(k)fluoranthene results in decreased expression of ACE2 mRNA

NCBI chr X:15,518,197...15,607,211
Ensembl chr X:15,494,566...15,607,236

G

alkaline ceramidase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ACER1 mRNA

NCBI chr19:6,306,142...6,360,368
Ensembl chr19:6,306,142...6,333,612

G

acyl-CoA thioesterase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ACOT1 mRNA

NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796

G

acyl-CoA thioesterase 9

increases expression

benzo(k)fluoranthene results in increased expression of ACOT9 mRNA

NCBI chr X:23,701,055...23,743,276
Ensembl chr X:23,701,055...23,766,475

G

acyl-CoA oxidase 1

increases expression

benzo(k)fluoranthene results in increased expression of ACOX1 mRNA

NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177

G

acyl-CoA oxidase 2

decreases expression

benzo(k)fluoranthene results in decreased expression of ACOX2 mRNA

NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283

G

acyl-CoA synthetase family member 3

increases expression

benzo(k)fluoranthene results in increased expression of ACSF3 mRNA

NCBI chr16:89,093,852...89,156,233
Ensembl chr16:89,088,375...89,164,121

G

acyl-CoA synthetase long chain family member 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ACSL1 mRNA

NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818

G

actin gamma 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ACTG1 mRNA

NCBI chr17:81,509,971...81,512,799
Ensembl chr17:81,509,413...81,523,847

G

activin A receptor like type 1

increases expression

benzo(k)fluoranthene results in increased expression of ACVRL1 mRNA

NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361

G

ADAM metallopeptidase domain 11

decreases expression

benzo(k)fluoranthene results in decreased expression of ADAM11 mRNA

NCBI chr17:44,758,988...44,781,846
Ensembl chr17:44,758,988...44,781,846

G

ADAM like decysin 1

increases expression

benzo(k)fluoranthene results in increased expression of ADAMDEC1 mRNA

NCBI chr 8:24,384,285...24,406,013
Ensembl chr 8:24,384,285...24,406,013

G

ADAM metallopeptidase with thrombospondin type 1 motif 14

increases expression

benzo(k)fluoranthene results in increased expression of ADAMTS14 mRNA

NCBI chr10:70,672,506...70,762,441
Ensembl chr10:70,672,506...70,762,441

G

adhesion G protein-coupled receptor F4

decreases expression

benzo(k)fluoranthene results in decreased expression of ADGRF4 mRNA

NCBI chr 6:47,698,580...47,722,014
Ensembl chr 6:47,685,864...47,722,021

G

adhesion G protein-coupled receptor G3

increases expression

benzo(k)fluoranthene results in increased expression of ADGRG3 mRNA

NCBI chr16:57,665,629...57,689,378
Ensembl chr16:57,668,277...57,689,378

G

adenosine kinase

decreases expression

benzo(k)fluoranthene results in decreased expression of ADK mRNA

NCBI chr10:74,151,221...74,709,290
Ensembl chr10:74,151,202...74,709,963

G

adrenoceptor beta 1

increases expression

benzo(k)fluoranthene results in increased expression of ADRB1 mRNA

NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904

G

adrenoceptor beta 2

increases expression

benzo(k)fluoranthene results in increased expression of ADRB2 mRNA

NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623

G

androgen dependent TFPI regulating protein

decreases expression

benzo(k)fluoranthene results in decreased expression of ADTRP mRNA

NCBI chr 6:11,713,523...11,778,803
Ensembl chr 6:11,712,054...11,807,046

G

aryl hydrocarbon receptor

multiple interactions
increases activity

[benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [indeno(1,2,3-cd)pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene] promotes the reaction [pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with pyrene] promotes the reaction [fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [chrysene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(k)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(j)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; [Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benz(a)anthracene results in increased activity of AHR protein]; [benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; AHR protein promotes the reaction [benzo(k)fluoranthene results in increased expression of ABCG2 protein]; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; benzo(k)fluoranthene binds to and results in increased activity of AHR protein; benzo(k)fluoranthene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]

PMID:11525907 PMID:12371477 PMID:12799773 PMID:12850102 PMID:15917307 More...

NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152

G

aryl hydrocarbon receptor repressor

increases expression

benzo(k)fluoranthene results in increased expression of AHRR mRNA

NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291

G

alpha hemoglobin stabilizing protein

increases expression

benzo(k)fluoranthene results in increased expression of AHSP mRNA

NCBI chr16:31,527,900...31,528,803
Ensembl chr16:31,527,900...31,528,803

G

allograft inflammatory factor 1

increases expression

benzo(k)fluoranthene results in increased expression of AIF1 mRNA

NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021

G

androgen induced 1

increases expression

benzo(k)fluoranthene results in increased expression of AIG1 mRNA

NCBI chr 6:143,059,213...143,343,883
Ensembl chr 6:143,060,496...143,341,058

G

aldo-keto reductase family 1 member B

increases expression

benzo(k)fluoranthene results in increased expression of AKR1B1 mRNA

NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284

G

aldo-keto reductase family 1 member C1

increases expression

benzo(k)fluoranthene results in increased expression of AKR1C1 mRNA

NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283

G

AKT serine/threonine kinase 2

decreases expression

benzo(k)fluoranthene results in decreased expression of AKT2 mRNA

NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536

G

AKT interacting protein

decreases expression

benzo(k)fluoranthene results in decreased expression of AKTIP mRNA

NCBI chr16:53,491,040...53,504,412
Ensembl chr16:53,491,040...53,504,411

G

aldehyde dehydrogenase 1 family member A2

decreases expression

benzo(k)fluoranthene results in decreased expression of ALDH1A2 mRNA

NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866

G

aldehyde dehydrogenase 5 family member A1

decreases expression

benzo(k)fluoranthene results in decreased expression of ALDH5A1 mRNA

NCBI chr 6:24,494,969...24,537,207
Ensembl chr 6:24,494,867...24,537,207

G

arachidonate 12-lipoxygenase, 12R type

decreases expression

benzo(k)fluoranthene results in decreased expression of ALOX12B mRNA

NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716

G

alpha-1-microglobulin/bikunin precursor

decreases expression

benzo(k)fluoranthene results in decreased expression of AMBP mRNA

NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328

G

amidohydrolase domain containing 1

decreases expression

benzo(k)fluoranthene results in decreased expression of AMDHD1 mRNA

NCBI chr12:95,943,331...95,968,720
Ensembl chr12:95,943,331...95,968,720

G

archaelysin family metallopeptidase 1

increases expression

benzo(k)fluoranthene results in increased expression of AMZ1 mRNA

NCBI chr 7:2,679,522...2,765,138
Ensembl chr 7:2,679,522...2,775,500

G

acidic nuclear phosphoprotein 32 family member A

decreases expression

benzo(k)fluoranthene results in decreased expression of ANP32A mRNA

NCBI chr15:68,778,535...68,820,895
Ensembl chr15:68,778,535...68,820,897

G

annexin A3

decreases expression

benzo(k)fluoranthene results in decreased expression of ANXA3 mRNA

NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451

G

amyloid beta precursor protein binding family B member 1

decreases expression

benzo(k)fluoranthene results in decreased expression of APBB1 mRNA

NCBI chr11:6,395,124...6,419,453
Ensembl chr11:6,395,125...6,419,414

G

apolipoprotein B

decreases expression

benzo(k)fluoranthene results in decreased expression of APOB mRNA

NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073

G

apolipoprotein B mRNA editing enzyme catalytic subunit 3H

decreases expression

benzo(k)fluoranthene results in decreased expression of APOBEC3 mRNA

NCBI chr22:39,097,244...39,104,067
Ensembl chr22:39,097,224...39,104,067

G

androgen receptor

multiple interactions
decreases activity

benzo(k)fluoranthene inhibits the reaction [Metribolone results in increased activity of AR protein]
benzo(k)fluoranthene results in decreased activity of AR protein

PMID:12799773 PMID:18324785

NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619

G

ARF GTPase 6

decreases expression

benzo(k)fluoranthene results in decreased expression of ARF6 mRNA

NCBI chr14:49,893,082...49,897,054
Ensembl chr14:49,893,079...49,897,054

G

armadillo repeat containing X-linked 4

decreases expression

benzo(k)fluoranthene results in decreased expression of ARMCX4 mRNA

NCBI chr X:101,418,278...101,535,988
Ensembl chr X:101,418,287...101,533,459

G

arrestin beta 1

increases expression

benzo(k)fluoranthene results in increased expression of ARRB1 mRNA

NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705

G

arrestin domain containing 4

decreases expression

benzo(k)fluoranthene results in decreased expression of ARRDC4 mRNA

NCBI chr15:97,960,703...97,973,833
Ensembl chr15:97,960,703...97,973,833

G

N-acylsphingosine amidohydrolase 2

decreases expression

benzo(k)fluoranthene results in decreased expression of ASAH2 mRNA

NCBI chr10:50,184,861...50,251,516
Ensembl chr10:50,182,778...50,279,720

G

ankyrin repeat and SOCS box containing 10

decreases expression

benzo(k)fluoranthene results in decreased expression of ASB10 mRNA

NCBI chr 7:151,175,698...151,187,792
Ensembl chr 7:151,175,698...151,187,832

G

asparaginase

decreases expression

benzo(k)fluoranthene results in decreased expression of ASPG mRNA

NCBI chr14:104,085,700...104,115,582
Ensembl chr14:104,085,686...104,115,582

G

atos homolog B

increases expression

benzo(k)fluoranthene results in increased expression of ATOSB mRNA

NCBI chr 9:35,104,117...35,116,380
Ensembl chr 9:35,104,112...35,116,341

G

ATPase phospholipid transporting 10A (putative)

increases expression

benzo(k)fluoranthene results in increased expression of ATP10A mRNA

NCBI chr15:25,672,237...25,865,088
Ensembl chr15:25,677,273...25,865,184

G

ATPase plasma membrane Ca2+ transporting 2

increases expression

benzo(k)fluoranthene results in increased expression of ATP2B2 mRNA

NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007

G

ATPase H+ transporting V0 subunit a4

increases expression

benzo(k)fluoranthene results in increased expression of ATP6V0A4 mRNA

NCBI chr 7:138,706,294...138,798,196
Ensembl chr 7:138,706,294...138,799,560

G

BAG cochaperone 4

decreases expression

benzo(k)fluoranthene results in decreased expression of BAG4 mRNA

NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301

G

BAR/IMD domain containing adaptor protein 2

increases expression

benzo(k)fluoranthene results in increased expression of BAIAP2 mRNA

NCBI chr17:81,035,151...81,117,434
Ensembl chr17:81,035,122...81,117,434

G

bromodomain adjacent to zinc finger domain 2B

decreases expression

benzo(k)fluoranthene results in decreased expression of BAZ2B mRNA

NCBI chr 2:159,315,312...159,712,442
Ensembl chr 2:159,315,312...159,616,569

G

BAF chromatin remodeling complex subunit BCL7B

increases expression

benzo(k)fluoranthene results in increased expression of BCL7B mRNA

NCBI chr 7:73,536,356...73,557,690
Ensembl chr 7:73,536,356...73,557,690

G

baculoviral IAP repeat containing 5

increases expression

benzo(k)fluoranthene results in increased expression of BIRC5 mRNA

NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636

G

bleomycin hydrolase

decreases expression

benzo(k)fluoranthene results in decreased expression of BLMH mRNA

NCBI chr17:30,248,203...30,291,944
Ensembl chr17:30,248,203...30,292,056

G

B cell linker

decreases expression

benzo(k)fluoranthene results in decreased expression of BLNK mRNA

NCBI chr10:96,189,171...96,271,569
Ensembl chr10:96,189,171...96,271,587

G

basic helix-loop-helix ARNT like 1

decreases expression

benzo(k)fluoranthene results in decreased expression of BMAL1 mRNA

NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266

G

Bcl2 modifying factor

increases expression

benzo(k)fluoranthene results in increased expression of BMF mRNA

NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892

G

BCL2 interacting protein like

decreases expression

benzo(k)fluoranthene results in decreased expression of BNIPL mRNA

NCBI chr 1:151,036,586...151,047,720
Ensembl chr 1:151,036,321...151,047,720

G

BPI fold containing family A member 1

increases expression

benzo(k)fluoranthene results in increased expression of BPIFA1 mRNA

NCBI chr20:33,235,996...33,243,306
Ensembl chr20:33,235,995...33,243,311

G

bromodomain containing 2

decreases expression

benzo(k)fluoranthene results in decreased expression of BRD2 mRNA

NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505

G

complement C8 alpha chain

decreases expression

benzo(k)fluoranthene results in decreased expression of C8A mRNA

NCBI chr 1:56,854,797...56,918,223
Ensembl chr 1:56,854,768...56,918,223

G

carbonic anhydrase 14

decreases expression

benzo(k)fluoranthene results in decreased expression of CAR14 mRNA

NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078

G

carbonic anhydrase 2

increases expression

benzo(k)fluoranthene results in increased expression of CAR2 mRNA

NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493

G

cell adhesion molecule 1

decreases expression

benzo(k)fluoranthene results in decreased expression of CADM1 mRNA

NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957

G

calcium/calmodulin dependent protein kinase kinase 2

increases expression

benzo(k)fluoranthene results in increased expression of CAMKK2 mRNA

NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308

G

calpain 8

decreases expression

benzo(k)fluoranthene results in decreased expression of CAPN8 mRNA

NCBI chr 1:223,541,616...223,665,701
Ensembl chr 1:223,538,007...223,665,723

G

calpain small subunit 2

decreases expression

benzo(k)fluoranthene results in decreased expression of CAPNS2 mRNA

NCBI chr16:55,566,684...55,567,687
Ensembl chr16:55,566,684...55,567,687

G

capping protein regulator and myosin 1 linker 2

decreases expression

benzo(k)fluoranthene results in decreased expression of CARMIL2 mRNA

NCBI chr16:67,645,144...67,657,569
Ensembl chr16:67,644,988...67,657,569

G

carbonyl reductase 3

increases expression

benzo(k)fluoranthene results in increased expression of CBR3 mRNA

NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562

G

coiled-coil domain containing 117

decreases expression

benzo(k)fluoranthene results in decreased expression of CCDC117 mRNA

NCBI chr22:28,772,695...28,789,301
Ensembl chr22:28,772,674...28,789,301

G

C-C motif chemokine ligand 19

increases expression

benzo(k)fluoranthene results in increased expression of CCL19 mRNA

NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276

G

C-C motif chemokine ligand 5

decreases expression

benzo(k)fluoranthene results in decreased expression of CCL5 mRNA

NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793

G

cyclin D1

increases expression

benzo(k)fluoranthene results in increased expression of CCND1 mRNA

NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474

G

cyclin J like

decreases expression

benzo(k)fluoranthene results in decreased expression of CCNJL mRNA

NCBI chr 5:160,249,083...160,339,570
Ensembl chr 5:160,249,083...160,345,396

G

cyclin O

increases expression

benzo(k)fluoranthene results in increased expression of CCNO mRNA

NCBI chr 5:55,231,152...55,233,608
Ensembl chr 5:55,231,152...55,233,608

G

CD36 molecule (CD36 blood group)

affects expression

benzo(k)fluoranthene affects the expression of CD36 mRNA

NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277

G

CD52 molecule

increases expression

benzo(k)fluoranthene results in increased expression of CD52 mRNA

NCBI chr 1:26,317,958...26,320,523
Ensembl chr 1:26,317,958...26,320,523

G

CD74 molecule

increases expression

benzo(k)fluoranthene results in increased expression of CD74 mRNA

NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969

G

cell division cycle 20

increases expression

benzo(k)fluoranthene results in increased expression of CDC20 mRNA

NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203

G

CCAAT enhancer binding protein epsilon

increases expression

benzo(k)fluoranthene results in increased expression of CEBPE mRNA

NCBI chr14:23,117,306...23,119,255
Ensembl chr14:23,117,036...23,120,256

G

cadherin EGF LAG seven-pass G-type receptor 2

decreases expression

benzo(k)fluoranthene results in decreased expression of CELSR2 mRNA

NCBI chr 1:109,249,539...109,275,751
Ensembl chr 1:109,249,539...109,275,751

G

carboxylesterase 1

increases expression

benzo(k)fluoranthene results in increased expression of CES1 mRNA

NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337

G

carboxylesterase 2

increases expression

benzo(k)fluoranthene results in increased expression of CES2 mRNA

NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096

G

complement factor D

increases expression

benzo(k)fluoranthene results in increased expression of CFD mRNA

NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884

G

cingulin

decreases expression

benzo(k)fluoranthene results in decreased expression of CGN mRNA

NCBI chr 1:151,510,170...151,538,692
Ensembl chr 1:151,510,510...151,538,692

G

calcineurin like EF-hand protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of CHP1 mRNA

NCBI chr15:41,231,268...41,281,887
Ensembl chr15:41,230,839...41,281,887

G

cholinergic receptor nicotinic beta 1 subunit

decreases expression

benzo(k)fluoranthene results in decreased expression of CHRNB1 mRNA

NCBI chr17:7,445,061...7,457,710
Ensembl chr17:7,445,061...7,457,710

G

carbohydrate sulfotransferase 15

increases expression

benzo(k)fluoranthene results in increased expression of CHST15 mRNA

NCBI chr10:124,007,668...124,093,598
Ensembl chr10:124,007,668...124,093,598

G

claudin 17

decreases expression

benzo(k)fluoranthene results in decreased expression of CLDN17 mRNA

NCBI chr21:30,165,565...30,166,805
Ensembl chr21:30,165,565...30,166,805

G

C-type lectin domain family 1 member B

increases expression

benzo(k)fluoranthene results in increased expression of CLEC1B mRNA

NCBI chr12:9,993,075...10,001,899
Ensembl chr12:9,985,642...10,013,424

G

C-type lectin domain family 4 member G

decreases expression

benzo(k)fluoranthene results in decreased expression of CLEC4G mRNA

NCBI chr19:7,728,957...7,732,110
Ensembl chr19:7,728,957...7,733,906

G

C-type lectin domain containing 6A

increases expression

benzo(k)fluoranthene results in increased expression of CLEC4N mRNA

NCBI chr12:8,455,962...8,478,330
Ensembl chr12:8,455,962...8,478,330

G

C-type lectin domain containing 7A

increases expression

benzo(k)fluoranthene results in increased expression of CLEC7A mRNA

NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258

G

C-type lectin domain containing 9A

decreases expression

benzo(k)fluoranthene results in decreased expression of CLEC9A mRNA

NCBI chr12:10,030,682...10,066,031
Ensembl chr12:10,030,678...10,066,031

G

centriolin

decreases expression

benzo(k)fluoranthene results in decreased expression of CNTRL mRNA

NCBI chr 9:121,074,955...121,177,610
Ensembl chr 9:121,074,660...121,177,729

G

collagen type XIV alpha 1 chain

affects expression

benzo(k)fluoranthene affects the expression of COL14A1 mRNA

NCBI chr 8:120,124,454...120,373,573
Ensembl chr 8:120,059,780...120,373,573

G

collagen type II alpha 1 chain

decreases expression

benzo(k)fluoranthene results in decreased expression of COL2A1 mRNA

NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554

G

collagen type III alpha 1 chain

increases expression

benzo(k)fluoranthene results in increased expression of COL3A1 mRNA

NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746

G

collagen type IV alpha 6 chain

decreases expression

benzo(k)fluoranthene results in decreased expression of COL4A6 mRNA

NCBI chr X:108,155,614...108,439,458
Ensembl chr X:108,155,607...108,439,497

G

COP9 signalosome subunit 4

decreases expression

benzo(k)fluoranthene results in decreased expression of COPS4 mRNA

NCBI chr 4:83,035,183...83,075,818
Ensembl chr 4:83,034,447...83,075,818

G

cytochrome c oxidase subunit 7C

decreases expression

benzo(k)fluoranthene results in decreased expression of COX7C mRNA

NCBI chr 5:86,617,941...86,620,962
Ensembl chr 5:86,617,928...86,620,962

G

cytoplasmic polyadenylation element binding protein 1

increases expression

benzo(k)fluoranthene results in increased expression of CPEB1 mRNA

NCBI chr15:82,543,201...82,648,795
Ensembl chr15:82,543,201...82,648,861

G

cytoplasmic polyadenylation element binding protein 3

increases expression

benzo(k)fluoranthene results in increased expression of CPEB3 mRNA

NCBI chr10:92,046,692...92,291,233
Ensembl chr10:92,046,692...92,291,078

G

ceramide-1-phosphate transfer protein

decreases expression

benzo(k)fluoranthene results in decreased expression of CPTP mRNA

NCBI chr 1:1,324,802...1,328,896
Ensembl chr 1:1,324,756...1,328,896

G

carboxypeptidase Z

increases expression

benzo(k)fluoranthene results in increased expression of CPZ mRNA

NCBI chr 4:8,592,765...8,619,752
Ensembl chr 4:8,592,660...8,619,759

G

cellular retinoic acid binding protein 2

decreases expression

benzo(k)fluoranthene results in decreased expression of CRABP2 mRNA

NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816

G

carnitine O-octanoyltransferase

decreases expression

benzo(k)fluoranthene results in decreased expression of CROT mRNA

NCBI chr 7:87,345,664...87,399,794
Ensembl chr 7:87,345,664...87,399,794

G

cysteine sulfinic acid decarboxylase

decreases expression

benzo(k)fluoranthene results in decreased expression of CSAD mRNA

NCBI chr12:53,157,663...53,181,351
Ensembl chr12:53,157,663...53,180,925

G

colony stimulating factor 2 receptor subunit beta

increases expression

benzo(k)fluoranthene results in increased expression of CSF2RB mRNA; benzo(k)fluoranthene results in increased expression of CSF2RB2 mRNA

NCBI chr22:36,913,628...36,940,439
Ensembl chr22:36,913,628...36,940,439

G

cysteine and glycine rich protein 3

increases expression

benzo(k)fluoranthene results in increased expression of CSRP3 mRNA

NCBI chr11:19,182,030...19,201,983
Ensembl chr11:19,182,030...19,210,571

G

cystatin C

decreases expression

benzo(k)fluoranthene results in decreased expression of CST3 mRNA

NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473

G

cystatin 8

increases expression

benzo(k)fluoranthene results in increased expression of CST8 mRNA

NCBI chr20:23,491,117...23,507,124
Ensembl chr20:23,491,101...23,496,010

G

catenin beta interacting protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of CTNNBIP1 mRNA

NCBI chr 1:9,848,276...9,910,269
Ensembl chr 1:9,848,276...9,910,336

G

cathepsin L

decreases expression

benzo(k)fluoranthene results in decreased expression of CTSL mRNA

NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469

G

CTTNBP2 N-terminal like

decreases expression

benzo(k)fluoranthene results in decreased expression of CTTNBP2NL mRNA

NCBI chr 1:112,391,087...112,461,164
Ensembl chr 1:112,396,214...112,463,456

G

C-X3-C motif chemokine receptor 1

increases expression

benzo(k)fluoranthene results in increased expression of CX3CR1 mRNA

NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735

G

C-X-C motif chemokine ligand 13

increases expression

benzo(k)fluoranthene results in increased expression of CXCL13 mRNA

NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834

G

C-X-C motif chemokine ligand 14

increases expression

benzo(k)fluoranthene results in increased expression of CXCL14 mRNA

NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279

G

C-X-C motif chemokine ligand 8

decreases expression

benzo(k)fluoranthene results in decreased expression of CXCL8 mRNA

NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716

G

C-X-C motif chemokine ligand 9

increases expression

benzo(k)fluoranthene results in increased expression of CXCL9 mRNA

NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509

G

C-X-C motif chemokine receptor 2

increases expression

benzo(k)fluoranthene results in increased expression of CXCR2 mRNA

NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251

G

cytochrome b5 type A

increases expression

benzo(k)fluoranthene results in increased expression of CYB5A mRNA

NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973

G

cytochrome b5 reductase 3

decreases expression

benzo(k)fluoranthene results in decreased expression of CYB5R3 mRNA

NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,615,730...42,720,870

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cytochrome P450 family 1 subfamily A member 1

multiple interactions
increases expression
increases activity
increases hydroxylation

[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [Docosahexaenoic Acids co-treated with benzo(k)fluoranthene] results in decreased expression of CYP1A1 mRNA; [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; benzo(k)fluoranthene affects the reaction [CYP1A1 protein results in increased hydroxylation of Estradiol]; benzo(k)fluoranthene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; Cadmium Chloride inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; Cadmium Chloride inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; HMOX1 protein affects the reaction [sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]]; HMOX1 protein affects the reaction [sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; lead nitrate promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; Mercuric Chloride promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 mRNA]; sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]
benzo(k)fluoranthene metabolite results in increased expression of CYP1A1 mRNA; benzo(k)fluoranthene results in increased expression of CYP1A1 mRNA; benzo(k)fluoranthene results in increased expression of CYP1A1 protein
fluoranthene inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]
[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A1 mRNA
CYP1A1 protein results in increased hydroxylation of benzo(k)fluoranthene

PMID:7750161 PMID:9586956 PMID:10190573 PMID:11162773 PMID:11370663 More...

NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536

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cytochrome P450 family 1 subfamily A member 2

increases expression
multiple interactions
decreases activity

benzo(k)fluoranthene results in increased expression of CYP1A2 mRNA; benzo(k)fluoranthene results in increased expression of CYP1A2 protein
[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA
sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 mRNA]; sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 protein]
benzo(k)fluoranthene results in decreased activity of CYP1A2 protein

PMID:7750161 PMID:11162773 PMID:11370663 PMID:17253728

NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607

G

cytochrome P450 family 1 subfamily B member 1

increases hydroxylation
increases expression
multiple interactions

CYP1B1 protein results in increased hydroxylation of benzo(k)fluoranthene
Benzo[k]fluoranthene increases expression of CYP1B1 mRNA in lung epithelial cell
benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA
[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA; benzo(k)fluoranthene affects the reaction [CYP1B1 protein results in increased hydroxylation of Estradiol]

CTD
RGD

PMID:15566942 PMID:17253728 PMID:17919675 PMID:19358281 PMID:24472612 More...

NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902

G

cytochrome P450 family 21 subfamily A member 2

increases expression

benzo(k)fluoranthene results in increased expression of CYP21A1 mRNA

NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644

G

cytochrome P450 family 2 subfamily B member 6

increases expression

benzo(k)fluoranthene results in increased expression of CYP2B10 mRNA

NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398

G

cytochrome P450 family 3 subfamily A member 5

decreases expression

benzo(k)fluoranthene results in decreased expression of CYP3A13 mRNA

NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

benzo(k)fluoranthene results in decreased expression of CYP8B1 mRNA

NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898

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cysteine rich transmembrane module containing 1

decreases expression

benzo(k)fluoranthene results in decreased expression of CYSTM1 mRNA

NCBI chr 5:140,175,188...140,243,789
Ensembl chr 5:140,175,156...140,282,052

G

dachshund family transcription factor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of DACH1 mRNA

NCBI chr13:71,437,966...71,867,204
Ensembl chr13:71,437,966...71,867,204

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

decreases expression

benzo(k)fluoranthene results in decreased expression of DAPP1 mRNA

NCBI chr 4:99,816,827...99,872,333
Ensembl chr 4:99,816,827...99,870,190

G

diazepam binding inhibitor, acyl-CoA binding protein

decreases expression

benzo(k)fluoranthene results in decreased expression of DBI mRNA

NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550

G

D-box binding PAR bZIP transcription factor

increases expression

benzo(k)fluoranthene results in increased expression of DBP mRNA

NCBI chr19:48,630,030...48,637,379
Ensembl chr19:48,630,030...48,637,379

G

DEAH-box helicase 15

decreases expression

benzo(k)fluoranthene results in decreased expression of DHX15 mRNA

NCBI chr 4:24,527,475...24,584,554
Ensembl chr 4:24,517,441...24,584,554

G

dickkopf like acrosomal protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of DKKL1 mRNA

NCBI chr19:49,360,515...49,375,116
Ensembl chr19:49,361,783...49,375,116

G

doublesex and mab-3 related transcription factor 2

increases expression

benzo(k)fluoranthene results in increased expression of DMRT2 mRNA

NCBI chr 9:1,050,357...1,057,552
Ensembl chr 9:1,049,858...1,057,552

G

dynein axonemal intermediate chain 1

decreases expression

benzo(k)fluoranthene results in decreased expression of DNAI1 mRNA

NCBI chr 9:34,458,805...34,520,984
Ensembl chr 9:34,457,414...34,520,988

G

DnaJ heat shock protein family (Hsp40) member A1

decreases expression

benzo(k)fluoranthene results in decreased expression of DNAJA1 mRNA

NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907

G

DnaJ heat shock protein family (Hsp40) member B1

decreases expression

benzo(k)fluoranthene results in decreased expression of DNAJB1 mRNA

NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,513,789...14,560,391

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deoxyribonuclease 1 like 2

decreases expression

benzo(k)fluoranthene results in decreased expression of DNASE1L2 mRNA

NCBI chr16:2,236,444...2,238,711
Ensembl chr16:2,235,816...2,238,711

G

dipeptidyl peptidase 3

decreases expression

benzo(k)fluoranthene results in decreased expression of DPP3 mRNA

NCBI chr11:66,480,434...66,509,657
Ensembl chr11:66,480,013...66,509,657

G

dermatopontin

decreases expression

benzo(k)fluoranthene results in decreased expression of DPT mRNA

NCBI chr 1:168,695,468...168,729,206
Ensembl chr 1:168,695,468...168,729,206

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dopamine receptor D1

multiple interactions

[Particulate Matter results in increased abundance of benzo(k)fluoranthene] which results in decreased expression of DRD1 mRNA

NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182

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desmocollin 1

decreases expression

benzo(k)fluoranthene results in decreased expression of DSC1 mRNA

NCBI chr18:31,129,236...31,162,856
Ensembl chr18:31,129,236...31,162,856

G

dystonin

decreases expression

benzo(k)fluoranthene results in decreased expression of DST mRNA

NCBI chr 6:56,457,996...56,954,830
Ensembl chr 6:56,457,987...56,954,830

G

dystrobrevin alpha

increases expression

benzo(k)fluoranthene results in increased expression of DTNA mRNA

NCBI chr18:34,493,312...34,891,844
Ensembl chr18:34,493,291...34,891,844

G

dual oxidase maturation factor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of DUOXA1 mRNA

NCBI chr15:45,117,366...45,129,879
Ensembl chr15:45,117,366...45,129,938

G

dual specificity phosphatase 14

decreases expression

benzo(k)fluoranthene results in decreased expression of DUSP14 mRNA

NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501

G

EF-hand domain family member D2

increases expression

benzo(k)fluoranthene results in increased expression of EFHD2 mRNA

NCBI chr 1:15,409,888...15,430,339
Ensembl chr 1:15,409,888...15,430,339

G

ephrin B2

decreases expression

benzo(k)fluoranthene results in decreased expression of EFNB2 mRNA

NCBI chr13:106,489,745...106,535,662
Ensembl chr13:106,489,745...106,535,662

G

EH domain containing 1

affects expression

benzo(k)fluoranthene affects the expression of EHD1 mRNA

NCBI chr11:64,851,642...64,879,693
Ensembl chr11:64,851,642...64,888,296

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eukaryotic translation initiation factor 3 subunit I

decreases expression

benzo(k)fluoranthene results in decreased expression of EIF3I mRNA

NCBI chr 1:32,222,407...32,236,170
Ensembl chr 1:32,221,077...32,245,397

G

E74 like ETS transcription factor 5

decreases expression

benzo(k)fluoranthene results in decreased expression of ELF5 mRNA

NCBI chr11:34,478,791...34,513,794
Ensembl chr11:34,478,791...34,525,193

G

ELOVL fatty acid elongase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ELOVL1 mRNA

NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074

G

ELOVL fatty acid elongase 4

decreases expression

benzo(k)fluoranthene results in decreased expression of ELOVL4 mRNA

NCBI chr 6:79,914,814...79,947,553
Ensembl chr 6:79,914,814...79,947,553

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ELOVL fatty acid elongase 6

decreases expression

benzo(k)fluoranthene results in decreased expression of ELOVL6 mRNA

NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199

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endonuclease, poly(U) specific

affects expression

benzo(k)fluoranthene affects the expression of ENDOU mRNA

NCBI chr12:47,709,734...47,725,490
Ensembl chr12:47,709,734...47,725,567

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energy homeostasis associated

decreases expression

benzo(k)fluoranthene results in decreased expression of ENHO mRNA

NCBI chr 9:34,521,043...34,522,990
Ensembl chr 9:34,521,043...34,522,990

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ectonucleoside triphosphate diphosphohydrolase 2

increases expression

benzo(k)fluoranthene results in increased expression of ENTPD2 mRNA

NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061

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erythrocyte membrane protein band 4.1 like 3

decreases expression

benzo(k)fluoranthene results in decreased expression of EPB41L3 mRNA

NCBI chr18:5,392,386...5,630,663
Ensembl chr18:5,392,381...5,630,700

G

erb-b2 receptor tyrosine kinase 2

decreases expression

benzo(k)fluoranthene results in decreased expression of ERBB2 mRNA

NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426

G

endoregulin

increases expression

benzo(k)fluoranthene results in increased expression of ERLN mRNA

NCBI chr17:75,646,251...75,647,974
Ensembl chr17:75,646,243...75,647,975

G

endothelial cell specific molecule 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ESM1 mRNA

NCBI chr 5:54,977,867...54,985,593
Ensembl chr 5:54,977,867...55,022,671

G

estrogen receptor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of ESR1 protein

PMID:18634860 PMID:21783948

NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619

G

extended synaptotagmin 3

decreases expression

benzo(k)fluoranthene results in decreased expression of ESYT3 mRNA

NCBI chr 3:138,434,616...138,481,686
Ensembl chr 3:138,434,586...138,481,686

G

ETS proto-oncogene 1, transcription factor

increases expression
multiple interactions

benzo(k)fluoranthene results in increased expression of ETS1 mRNA
Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of ETS1 mRNA]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of ETS1 mRNA]

NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558

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exocyst complex component 3 like 2

increases expression

benzo(k)fluoranthene results in increased expression of EXOC3L2 mRNA

NCBI chr19:45,212,370...45,245,407
Ensembl chr19:45,212,370...45,245,407

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fatty acid binding protein 12

increases expression

benzo(k)fluoranthene results in increased expression of FABP12 mRNA

NCBI chr 8:81,524,981...81,590,139
Ensembl chr 8:81,524,981...81,590,139

G

fatty acid binding protein 4

decreases expression

benzo(k)fluoranthene results in decreased expression of FABP4 mRNA

NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236

G

fatty acid binding protein 5

increases expression

benzo(k)fluoranthene results in increased expression of FABP5 mRNA

NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777

G

family with sequence similarity 43 member A

increases expression

benzo(k)fluoranthene results in increased expression of FAM43A mRNA

NCBI chr 3:194,685,883...194,689,037
Ensembl chr 3:194,685,883...194,689,037

G

family with sequence similarity 89 member A

decreases expression

benzo(k)fluoranthene results in decreased expression of FAM89A mRNA

NCBI chr 1:231,018,958...231,040,254
Ensembl chr 1:231,018,958...231,040,254

G

Fas ligand

decreases expression

benzo(k)fluoranthene results in decreased expression of FASL mRNA

NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876

G

FER tyrosine kinase

decreases expression

benzo(k)fluoranthene results in decreased expression of FER mRNA

NCBI chr 5:108,747,897...109,196,841
Ensembl chr 5:108,747,841...109,196,841

G

fibroblast growth factor 9

increases expression
increases expression

benzo(k)fluoranthene results in increased expression of FGF9 mRNA
Benzo[k]fluoranthene increases expression of FGF9 mRNA in lung cell

CTD
RGD

PMID:19358281 PMID:19358281

NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498

G

fragile histidine triad diadenosine triphosphatase

increases expression

benzo(k)fluoranthene results in increased expression of FHIT mRNA

NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459

G

fin bud initiation factor homolog

decreases expression

benzo(k)fluoranthene results in decreased expression of FIBIN mRNA

NCBI chr11:26,994,112...26,997,087
Ensembl chr11:26,994,112...26,997,087

G

firre intergenic repeating RNA element

decreases expression

benzo(k)fluoranthene results in decreased expression of FIRRE mRNA

NCBI chr X:131,691,525...131,830,643
Ensembl chr X:131,688,779...131,830,928

G

filamin B

decreases expression

benzo(k)fluoranthene results in decreased expression of FLNB mRNA

NCBI chr 3:58,008,422...58,172,251
Ensembl chr 3:58,008,398...58,172,251

G

fibronectin leucine rich transmembrane protein 2

decreases expression

benzo(k)fluoranthene results in decreased expression of FLRT2 mRNA

NCBI chr14:85,530,144...85,654,428
Ensembl chr14:85,530,144...85,654,428

G

flavin containing dimethylaniline monoxygenase 3

increases expression

benzo(k)fluoranthene results in increased expression of FMO3 mRNA

NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819

G

fructosamine 3 kinase

decreases expression

benzo(k)fluoranthene results in decreased expression of FN3K mRNA

NCBI chr17:82,735,615...82,751,196
Ensembl chr17:82,735,615...82,751,196

G

formin binding protein 1

increases expression

benzo(k)fluoranthene results in increased expression of FNBP1 mRNA

NCBI chr 9:129,887,187...130,053,879
Ensembl chr 9:129,887,187...130,043,189

G

fibronectin type III domain containing 5

increases expression

benzo(k)fluoranthene results in increased expression of FNDC5 mRNA

NCBI chr 1:32,862,268...32,872,484
Ensembl chr 1:32,862,268...32,872,482

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

benzo(k)fluoranthene results in increased expression of FOS mRNA

NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190

G

forkhead box P1

decreases expression

benzo(k)fluoranthene results in decreased expression of FOXP1 mRNA

NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978

G

forkhead box Q1

increases expression

benzo(k)fluoranthene results in increased expression of FOXQ1 mRNA

NCBI chr 6:1,312,098...1,314,758
Ensembl chr 6:1,312,098...1,314,758

G

FRAS1 related extracellular matrix 1

decreases expression

benzo(k)fluoranthene results in decreased expression of FREM1 mRNA

NCBI chr 9:14,737,152...14,910,995
Ensembl chr 9:14,737,152...14,910,995

G

follistatin

increases expression

benzo(k)fluoranthene results in increased expression of FST mRNA

NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134

G

FXYD domain containing ion transport regulator 2

increases expression

benzo(k)fluoranthene results in increased expression of FXYD2 mRNA

NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

benzo(k)fluoranthene results in decreased expression of G6PC1 mRNA

NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438

G

glucose-6-phosphate dehydrogenase

decreases expression

benzo(k)fluoranthene results in decreased expression of G6PDX mRNA

NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572

G

gamma-aminobutyric acid type A receptor subunit alpha3

decreases expression

benzo(k)fluoranthene results in decreased expression of GABRA3 mRNA

NCBI chr X:152,166,234...152,451,315
Ensembl chr X:152,166,234...152,451,315

G

golgi associated RAB2 interactor 1A

decreases expression

benzo(k)fluoranthene results in decreased expression of GARIN1A mRNA

NCBI chr 7:128,671,629...128,709,166
Ensembl chr 7:128,671,693...128,687,877

G

growth arrest specific 6

increases expression

benzo(k)fluoranthene results in increased expression of GAS6 mRNA

NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076

G

glucosylceramidase beta 1

decreases expression

benzo(k)fluoranthene results in decreased expression of GBA1 mRNA

NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699

G

golgi brefeldin A resistant guanine nucleotide exchange factor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of GBF1 mRNA

NCBI chr10:102,230,643...102,382,896
Ensembl chr10:102,245,371...102,382,899

G

guanylate binding protein 1

increases expression

benzo(k)fluoranthene results in increased expression of GBP1 mRNA

NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360

G

growth differentiation factor 15

decreases expression

benzo(k)fluoranthene results in decreased expression of GDF15 mRNA

NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176

G

gap junction protein beta 4

decreases expression

benzo(k)fluoranthene results in decreased expression of GJB4 mRNA

NCBI chr 1:34,759,740...34,762,327
Ensembl chr 1:34,759,740...34,762,327

G

gap junction protein beta 6

decreases expression

benzo(k)fluoranthene results in decreased expression of GJB6 mRNA

NCBI chr13:20,221,962...20,232,319
Ensembl chr13:20,221,962...20,232,365

G

gastrokine 2

increases expression

benzo(k)fluoranthene results in increased expression of GKN2 mRNA

NCBI chr 2:68,945,232...68,952,893
Ensembl chr 2:68,945,232...68,952,893

G

galactosidase beta 1 like 2

decreases expression

benzo(k)fluoranthene results in decreased expression of GLB1L2 mRNA

NCBI chr11:134,331,988...134,376,324
Ensembl chr11:134,331,988...134,378,341

G

glycine decarboxylase

decreases expression

benzo(k)fluoranthene results in decreased expression of GLDC mRNA

NCBI chr 9:6,532,467...6,645,729
Ensembl chr 9:6,532,467...6,645,729

G

glutaredoxin

decreases expression

benzo(k)fluoranthene results in decreased expression of GLRX mRNA

NCBI chr 5:95,813,849...95,822,726
Ensembl chr 5:95,751,319...95,822,726

G

geminin DNA replication inhibitor

increases expression

benzo(k)fluoranthene results in increased expression of GMNN mRNA

NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099

G

glyceronephosphate O-acyltransferase

increases expression

benzo(k)fluoranthene results in increased expression of GNPAT mRNA

NCBI chr 1:231,241,212...231,277,973
Ensembl chr 1:231,241,207...231,277,973

G

glycoprotein Ib platelet subunit alpha

increases expression

benzo(k)fluoranthene results in increased expression of GP1BA mRNA

NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023

G

glycoprotein IX platelet

increases expression

benzo(k)fluoranthene results in increased expression of GP9 mRNA

NCBI chr 3:129,054,845...129,062,406
Ensembl chr 3:129,060,779...129,062,406

G

glycerophosphocholine phosphodiesterase 1

increases expression

benzo(k)fluoranthene results in increased expression of GPCPD1 mRNA

NCBI chr20:5,544,439...5,611,006
Ensembl chr20:5,544,404...5,611,006

G

glycoprotein M6A

decreases expression

benzo(k)fluoranthene results in decreased expression of GPM6A mRNA

NCBI chr 4:175,632,937...176,002,393
Ensembl chr 4:175,632,934...176,002,664

G

G protein-coupled receptor 160

decreases expression

benzo(k)fluoranthene results in decreased expression of GPR160 mRNA

NCBI chr 3:170,037,995...170,085,392
Ensembl chr 3:170,037,995...170,085,392

G

G protein-coupled receptor 162

decreases expression

benzo(k)fluoranthene results in decreased expression of GPR162 mRNA

NCBI chr12:6,821,821...6,827,421
Ensembl chr12:6,821,624...6,829,972

G

GRAM domain containing 1C

decreases expression

benzo(k)fluoranthene results in decreased expression of GRAMD1C mRNA

NCBI chr 3:113,828,192...113,947,174
Ensembl chr 3:113,828,182...113,947,174

G

GRAM domain containing 2B

decreases expression

benzo(k)fluoranthene results in decreased expression of GRAMD2B mRNA

NCBI chr 5:126,360,120...126,494,364
Ensembl chr 5:126,360,132...126,496,494

G

grainyhead like transcription factor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of GRHL1 mRNA

NCBI chr 2:9,951,693...10,002,277
Ensembl chr 2:9,951,693...10,002,277

G

grainyhead like transcription factor 3

decreases expression

benzo(k)fluoranthene results in decreased expression of GRHL3 mRNA

NCBI chr 1:24,319,357...24,364,482
Ensembl chr 1:24,199,558...24,364,482

G

glyoxylate and hydroxypyruvate reductase

decreases expression

benzo(k)fluoranthene results in decreased expression of GRHPR mRNA

NCBI chr 9:37,422,435...37,439,494
Ensembl chr 9:37,422,666...37,436,990

G

gastrin releasing peptide

decreases expression

benzo(k)fluoranthene results in decreased expression of GRP mRNA

NCBI chr18:59,219,189...59,230,771
Ensembl chr18:59,220,158...59,230,774

G

gasdermin E

increases expression

benzo(k)fluoranthene results in increased expression of GSDME mRNA

NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940

G

glutathione S-transferase mu 1

decreases expression
multiple interactions

benzo(k)fluoranthene results in decreased expression of GSTM1 mRNA
[Docosahexaenoic Acids co-treated with benzo(k)fluoranthene] results in decreased expression of GSTM1 protein

PMID:17253728 PMID:25956473

NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039

G

glutathione S-transferase pi 1

affects expression

benzo(k)fluoranthene affects the expression of GSTP1 mRNA

NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656

G

guanylate kinase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of GUK1 mRNA

NCBI chr 1:228,140,084...228,148,955
Ensembl chr 1:228,139,962...228,148,984

G

granzyme A

decreases expression

benzo(k)fluoranthene results in decreased expression of GZMA mRNA

NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252

G

granzyme B

decreases expression

benzo(k)fluoranthene results in decreased expression of GZMB mRNA

NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267

G

H1.2 linker histone, cluster member

increases expression

benzo(k)fluoranthene results in increased expression of H1F2 mRNA

NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,054,760...26,056,470

G

H4 clustered histone 3

decreases expression

benzo(k)fluoranthene results in decreased expression of H4C3 mRNA

NCBI chr 6:26,103,933...26,104,337
Ensembl chr 6:26,103,933...26,104,337

G

3-hydroxyanthranilate 3,4-dioxygenase

increases expression

benzo(k)fluoranthene results in increased expression of HAAO mRNA

NCBI chr 2:42,767,089...42,792,583
Ensembl chr 2:42,767,089...42,792,593

G

HAUS augmin like complex subunit 8

increases expression

benzo(k)fluoranthene results in increased expression of HAUS8 mRNA

NCBI chr19:17,049,729...17,075,533
Ensembl chr19:17,049,729...17,075,625

G

heme binding protein 2

decreases expression

benzo(k)fluoranthene results in decreased expression of HEBP2 mRNA

NCBI chr 6:138,403,531...138,422,197
Ensembl chr 6:138,403,531...138,422,197

G

homocysteine inducible ER protein with ubiquitin like domain 1

decreases expression

benzo(k)fluoranthene results in decreased expression of HERPUD1 mRNA

NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864

G

HIC ZBTB transcriptional repressor 1

increases expression

benzo(k)fluoranthene results in increased expression of HIC1 mRNA

NCBI chr17:2,055,103...2,063,241
Ensembl chr17:2,054,154...2,063,241

G

hypoxia inducible factor 1 subunit alpha

increases activity

benzo(k)fluoranthene results in increased activity of HIF1A protein

NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259

G

hypoxia inducible lipid droplet associated

decreases expression

benzo(k)fluoranthene results in decreased expression of HILPDA mRNA

NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418

G

major histocompatibility complex, class II, DM beta

increases expression

benzo(k)fluoranthene results in increased expression of H2-DMB1 mRNA

NCBI chr 6:32,934,636...32,941,028
Ensembl chr 6:32,934,629...32,941,028

G

major histocompatibility complex, class II, DQ alpha 1

increases expression

benzo(k)fluoranthene results in increased expression of H2-AA mRNA

NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062

G

major histocompatibility complex, class II, DQ beta 1

increases expression

benzo(k)fluoranthene results in increased expression of H2-AB1 mRNA

NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383

G

major histocompatibility complex, class II, DR beta 1

increases expression

benzo(k)fluoranthene results in increased expression of H2-EB1 mRNA

NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848

G

hemicentin 1

decreases expression

benzo(k)fluoranthene results in decreased expression of HMCN1 mRNA

NCBI chr 1:185,734,391...186,190,949
Ensembl chr 1:185,734,391...186,190,949

G

high mobility group AT-hook 1

decreases expression

benzo(k)fluoranthene results in decreased expression of HMGA1 mRNA

NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression

benzo(k)fluoranthene results in decreased expression of HMGCS2 mRNA

NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905

G

heme oxygenase 1

multiple interactions
increases expression
decreases expression

HMOX1 protein affects the reaction [sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]]; HMOX1 protein affects the reaction [sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]]
benzo(k)fluoranthene results in increased expression of HMOX1 mRNA
benzo(k)fluoranthene results in decreased expression of HMOX1 mRNA

PMID:19526463 PMID:26377693 PMID:26656082

NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214

G

hook microtubule tethering protein 3

increases expression

benzo(k)fluoranthene results in increased expression of HOOK3 mRNA

NCBI chr 8:42,896,978...43,030,535
Ensembl chr 8:42,896,946...43,030,535

G

heparanase

decreases expression

benzo(k)fluoranthene results in decreased expression of HPSE mRNA

NCBI chr 4:83,292,461...83,335,153
Ensembl chr 4:83,292,461...83,335,153

G

hydroxysteroid 17-beta dehydrogenase 2

decreases expression

benzo(k)fluoranthene results in decreased expression of HSD17B2 mRNA

NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534

G

hydroxysteroid 17-beta dehydrogenase 7

decreases expression

benzo(k)fluoranthene results in decreased expression of HSD17B7 mRNA

NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823

G

heat shock protein 90 beta family member 1

increases expression

benzo(k)fluoranthene results in increased expression of HSP90B1 mRNA

NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931

G

heat shock protein family A (Hsp70) member 1A

decreases expression

benzo(k)fluoranthene results in decreased expression of HSPA1A mRNA

NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946

G

HIV-1 Tat interactive protein 2

increases expression

benzo(k)fluoranthene results in increased expression of HTATIP2 mRNA

NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782

G

5-hydroxytryptamine receptor 2B

decreases expression

benzo(k)fluoranthene results in decreased expression of HTR2B mRNA

NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042

G

hydroxylysine kinase

decreases expression

benzo(k)fluoranthene results in decreased expression of HYKK mRNA

NCBI chr15:78,507,577...78,537,373
Ensembl chr15:78,507,564...78,537,372

G

insulin degrading enzyme

decreases expression

benzo(k)fluoranthene results in decreased expression of IDE mRNA

NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096

G

immediate early response 3

increases expression

benzo(k)fluoranthene results in increased expression of IER3 mRNA

NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548

G

interferon induced transmembrane protein 10

decreases expression

benzo(k)fluoranthene results in decreased expression of IFITM10 mRNA

NCBI chr11:1,732,406...1,750,595
Ensembl chr11:1,732,406...1,750,595

G

insulin like growth factor binding protein 2

affects expression

benzo(k)fluoranthene affects the expression of IGFBP2 mRNA

NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436

G

interleukin 18 receptor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of IL18R1 mRNA

NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777

G

interleukin 1 beta

increases expression

benzo(k)fluoranthene results in increased expression of IL1B mRNA

NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816

G

interleukin 1 receptor type 2

increases expression

benzo(k)fluoranthene results in increased expression of IL1R2 mRNA

NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544

G

interleukin 2 receptor subunit beta

decreases expression

benzo(k)fluoranthene results in decreased expression of IL2RB mRNA

NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118

G

interleukin 36 beta

decreases expression

benzo(k)fluoranthene results in decreased expression of IL36B mRNA

NCBI chr 2:113,022,089...113,052,867
Ensembl chr 2:113,022,089...113,052,867

G

interleukin 36 receptor antagonist

decreases expression

benzo(k)fluoranthene results in decreased expression of IL36RN mRNA

NCBI chr 2:113,058,638...113,064,744
Ensembl chr 2:113,058,638...113,065,382

G

ilvB acetolactate synthase like

decreases expression

benzo(k)fluoranthene results in decreased expression of ILVBL mRNA

NCBI chr19:15,114,987...15,125,786
Ensembl chr19:15,114,984...15,125,786

G

InaF motif containing 2

decreases expression

benzo(k)fluoranthene results in decreased expression of INAFM2 mRNA

NCBI chr15:40,323,692...40,326,715
Ensembl chr15:40,323,692...40,326,715

G

inositol polyphosphate-5-phosphatase B

decreases expression

benzo(k)fluoranthene results in decreased expression of INPP5B mRNA

NCBI chr 1:37,860,697...37,947,057
Ensembl chr 1:37,860,697...37,947,053

G

inositol polyphosphate-5-phosphatase F

decreases expression

benzo(k)fluoranthene results in decreased expression of INPP5F mRNA

NCBI chr10:119,726,050...119,829,147
Ensembl chr10:119,726,042...119,829,147

G

integrin subunit alpha 10

increases expression

benzo(k)fluoranthene results in increased expression of ITGA10 mRNA

NCBI chr 1:145,891,208...145,910,050
Ensembl chr 1:145,891,208...145,910,111

G

integrin subunit alpha 2

increases expression
multiple interactions

benzo(k)fluoranthene results in increased expression of ITGA2 mRNA
Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of ITGA2 mRNA]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of ITGA2 mRNA]

NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779

G

integrin subunit alpha L

decreases expression

benzo(k)fluoranthene results in decreased expression of ITGAL mRNA

NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567

G

integrin subunit beta 6

decreases expression

benzo(k)fluoranthene results in decreased expression of ITGB6 mRNA

NCBI chr 2:160,099,671...160,200,272
Ensembl chr 2:160,099,667...160,271,888

G

integrin subunit beta 7

increases expression

benzo(k)fluoranthene results in increased expression of ITGB7 mRNA

NCBI chr12:53,191,323...53,207,251
Ensembl chr12:53,191,323...53,207,282

G

junction adhesion molecule like

increases expression

benzo(k)fluoranthene results in increased expression of JAML mRNA

NCBI chr11:118,193,725...118,225,011
Ensembl chr11:118,193,725...118,225,092

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of JUN mRNA]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of JUN mRNA]

PMID:12799773 PMID:21635667

NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048

G

lysine acetyltransferase 2B

decreases expression

benzo(k)fluoranthene results in decreased expression of KAT2B mRNA

NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404

G

potassium inwardly rectifying channel subfamily J member 10

increases expression

benzo(k)fluoranthene results in increased expression of KCNJ10 mRNA

NCBI chr 1:160,037,467...160,070,160
Ensembl chr 1:159,998,651...160,070,483

G

potassium inwardly rectifying channel subfamily J member 12

increases expression

benzo(k)fluoranthene results in increased expression of KCNJ12 mRNA

NCBI chr17:21,376,357...21,419,870
Ensembl chr17:21,376,357...21,419,870

G

potassium two pore domain channel subfamily K member 1

increases expression

benzo(k)fluoranthene results in increased expression of KCNK1 mRNA

NCBI chr 1:233,614,106...233,672,514
Ensembl chr 1:233,614,106...233,672,514

G

potassium channel tetramerization domain containing 10

decreases expression

benzo(k)fluoranthene results in decreased expression of KCTD10 mRNA

NCBI chr12:109,448,655...109,477,300
Ensembl chr12:109,448,655...109,477,359

G

potassium channel tetramerization domain containing 12

decreases expression

benzo(k)fluoranthene results in decreased expression of KCTD12 mRNA

NCBI chr13:76,880,175...76,886,405
Ensembl chr13:76,880,175...76,886,405

G

potassium channel tetramerization domain containing 2

increases expression

benzo(k)fluoranthene results in increased expression of KCTD2 mRNA

NCBI chr17:75,032,571...75,065,886
Ensembl chr17:75,032,575...75,065,889

G

ketohexokinase

decreases expression

benzo(k)fluoranthene results in decreased expression of KHK mRNA

NCBI chr 2:27,086,772...27,100,762
Ensembl chr 2:27,086,772...27,100,762

G

kinesin family member C3

decreases expression

benzo(k)fluoranthene results in decreased expression of KIFC3 mRNA

NCBI chr16:57,758,217...57,862,858
Ensembl chr16:57,758,217...57,863,053

G

KLF transcription factor 2

increases expression

benzo(k)fluoranthene results in increased expression of KLF2 mRNA

NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685

G

kallikrein related peptidase 10

decreases expression

benzo(k)fluoranthene results in decreased expression of KLK10 mRNA

NCBI chr19:51,012,739...51,020,097
Ensembl chr19:51,012,739...51,020,175

G

kallikrein related peptidase 12

decreases expression

benzo(k)fluoranthene results in decreased expression of KLK12 mRNA

NCBI chr19:51,029,094...51,035,002
Ensembl chr19:51,029,092...51,035,230

G

kallikrein related peptidase 13

decreases expression

benzo(k)fluoranthene results in decreased expression of KLK13 mRNA

NCBI chr19:51,055,626...51,065,679
Ensembl chr19:51,055,626...51,065,114

G

kallikrein related peptidase 3

multiple interactions

alpha-naphthoflavone inhibits the reaction [benzo(k)fluoranthene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]]; alpha-naphthoflavone inhibits the reaction [benzo(k)fluoranthene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]]; benzo(k)fluoranthene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]; benzo(k)fluoranthene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]; Proadifen promotes the reaction [benzo(k)fluoranthene inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]]

NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764

G

killer cell lectin like receptor G1

decreases expression

benzo(k)fluoranthene results in decreased expression of KLRG1 mRNA

NCBI chr12:8,950,044...9,215,570
Ensembl chr12:8,950,044...9,010,760

G

keratin 32

decreases expression

benzo(k)fluoranthene results in decreased expression of KRT32 mRNA

NCBI chr17:41,459,513...41,467,386
Ensembl chr17:41,459,513...41,467,386

G

keratin 4

decreases expression

benzo(k)fluoranthene results in decreased expression of KRT4 mRNA

NCBI chr12:52,806,549...52,814,116
Ensembl chr12:52,806,549...52,814,116

G

keratin 72

decreases expression

benzo(k)fluoranthene results in decreased expression of KRT72 mRNA

NCBI chr12:52,585,589...52,602,953
Ensembl chr12:52,585,589...52,601,538

G

keratin 85

decreases expression

benzo(k)fluoranthene results in decreased expression of KRT85 mRNA

NCBI chr12:52,360,006...52,367,481
Ensembl chr12:52,360,006...52,367,481

G

keratin associated protein 10-8

decreases expression

benzo(k)fluoranthene results in decreased expression of KRTAP10-4 mRNA

NCBI chr21:44,612,079...44,612,954
Ensembl chr21:44,612,079...44,612,954

G

keratin associated protein 5-1

decreases expression

benzo(k)fluoranthene results in decreased expression of KRTAP5-3 mRNA

NCBI chr11:1,584,342...1,585,283
Ensembl chr11:1,584,342...1,585,283

G

keratin associated protein 5-5

decreases expression

benzo(k)fluoranthene results in decreased expression of KRTAP5-5 mRNA

NCBI chr11:1,629,775...1,630,930
Ensembl chr11:1,629,775...1,630,930

G

kynurenine aminotransferase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of KYAT1 mRNA

NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,832,942...128,882,494
Ensembl chr 9:128,832,942...128,882,494

G

laminin subunit alpha 1

increases expression

benzo(k)fluoranthene results in increased expression of LAMA1 mRNA

NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797

G

laminin subunit alpha 2

increases expression

benzo(k)fluoranthene results in increased expression of LAMA2 mRNA

NCBI chr 6:128,883,138...129,516,566
Ensembl chr 6:128,883,138...129,516,566

G

late cornified envelope like proline rich 1

decreases expression

benzo(k)fluoranthene results in decreased expression of LELP1 mRNA

NCBI chr 1:153,203,430...153,205,120
Ensembl chr 1:153,203,430...153,205,120

G

galectin 1

increases expression

benzo(k)fluoranthene results in increased expression of LGALS1 mRNA

NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802

G

galectin like

decreases expression

benzo(k)fluoranthene results in decreased expression of LGALSL mRNA

NCBI chr 2:64,454,162...64,461,381
Ensembl chr 2:64,453,969...64,461,381

G

LHFPL tetraspan subfamily member 6

decreases expression

benzo(k)fluoranthene results in decreased expression of LHFPL6 mRNA

NCBI chr13:39,342,892...39,603,193
Ensembl chr13:39,209,116...39,603,528

G

LIM domain kinase 1

increases expression

benzo(k)fluoranthene results in increased expression of LIMK1 mRNA

NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525

G

lipase family member M

decreases expression

benzo(k)fluoranthene results in decreased expression of LIPM mRNA

NCBI chr10:88,802,730...88,820,546
Ensembl chr10:88,802,730...88,820,546

G

lipase family member N

decreases expression

benzo(k)fluoranthene results in decreased expression of LIPN mRNA

NCBI chr10:88,757,226...88,779,626
Ensembl chr10:88,759,982...88,779,626

G

LIM domain 7

increases expression

benzo(k)fluoranthene results in increased expression of LMO7 mRNA

NCBI chr13:75,620,434...75,859,870
Ensembl chr13:75,620,434...75,859,870

G

lysyl oxidase like 1

decreases expression

benzo(k)fluoranthene results in decreased expression of LOXL1 mRNA

NCBI chr15:73,926,462...73,952,136
Ensembl chr15:73,925,989...73,952,137

G

lysophosphatidic acid receptor 6

increases expression

benzo(k)fluoranthene results in increased expression of LPAR6 mRNA

NCBI chr13:48,389,571...48,444,669
Ensembl chr13:48,389,567...48,444,704

G

LDL receptor related protein 4

increases expression

benzo(k)fluoranthene results in increased expression of LRP4 mRNA

NCBI chr11:46,856,717...46,918,550
Ensembl chr11:46,856,717...46,918,642

G

leucine rich repeat containing 20

decreases expression

benzo(k)fluoranthene results in decreased expression of LRRC20 mRNA

NCBI chr10:70,298,975...70,382,625
Ensembl chr10:70,298,970...70,382,650

G

leucine rich repeat containing 45

increases expression

benzo(k)fluoranthene results in increased expression of LRRC45 mRNA

NCBI chr17:82,023,305...82,031,151
Ensembl chr17:82,023,305...82,031,151

G

leucine rich repeat neuronal 3

increases expression

benzo(k)fluoranthene results in increased expression of LRRN3 mRNA

NCBI chr 7:111,091,127...111,125,454
Ensembl chr 7:111,091,006...111,125,454

G

lymphocyte specific protein 1

increases expression

benzo(k)fluoranthene results in increased expression of LSP1 mRNA

NCBI chr11:1,853,084...1,892,263
Ensembl chr11:1,850,904...1,892,267

G

lymphocyte antigen 6 family member S

increases expression

benzo(k)fluoranthene results in increased expression of LY6A mRNA

NCBI chr 8:143,040,839...143,076,471
Ensembl chr 8:143,040,839...143,048,319

G

lysozyme g1

decreases expression

benzo(k)fluoranthene results in decreased expression of LYG1 mRNA

NCBI chr 2:99,284,238...99,304,775
Ensembl chr 2:99,284,238...99,304,742

G

LY6/PLAUR domain containing 5

decreases expression

benzo(k)fluoranthene results in decreased expression of LYPD5 mRNA

NCBI chr19:43,795,927...43,820,634
Ensembl chr19:43,785,874...43,827,206

G

MET transcriptional regulator MACC1

decreases expression

benzo(k)fluoranthene results in decreased expression of MACC1 mRNA

NCBI chr 7:20,134,655...20,217,384
Ensembl chr 7:20,134,655...20,217,404

G

microtubule associated protein 2

decreases expression

benzo(k)fluoranthene results in decreased expression of MAP2 mRNA

NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147

G

mitogen-activated protein kinase 14

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]

NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511

G

membrane associated ring-CH-type finger 1

increases expression

benzo(k)fluoranthene results in increased expression of MARCHF1 mRNA

NCBI chr 4:163,524,298...164,384,019
Ensembl chr 4:163,524,298...164,384,050

G

membrane associated ring-CH-type finger 3

decreases expression

benzo(k)fluoranthene results in decreased expression of MARCHF3 mRNA

NCBI chr 5:126,867,714...127,030,558
Ensembl chr 5:126,867,714...127,030,558

G

MAS1 proto-oncogene, G protein-coupled receptor

increases expression

benzo(k)fluoranthene results in increased expression of MAS1 mRNA

NCBI chr 6:159,888,787...159,917,447
Ensembl chr 6:159,890,988...159,917,447

G

methionine adenosyltransferase 2A

decreases expression

benzo(k)fluoranthene results in decreased expression of MAT2A mRNA

NCBI chr 2:85,539,168...85,545,281
Ensembl chr 2:85,539,168...85,545,281

G

myoglobin

increases expression

benzo(k)fluoranthene results in increased expression of MB mRNA

NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951

G

melanoma cell adhesion molecule

decreases expression

benzo(k)fluoranthene results in decreased expression of MCAM mRNA

NCBI chr11:119,308,529...119,317,130
Ensembl chr11:119,308,529...119,321,521

G

mitochondrial calcium uniporter

decreases expression

benzo(k)fluoranthene results in decreased expression of MCU mRNA

NCBI chr10:72,692,143...72,887,694
Ensembl chr10:72,692,143...72,887,694

G

MEFV innate immunity regulator, pyrin

increases expression

benzo(k)fluoranthene results in increased expression of MEFV mRNA

NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633

G

Meis homeobox 2

increases expression

benzo(k)fluoranthene results in increased expression of MEIS2 mRNA

NCBI chr15:36,889,204...37,101,311
Ensembl chr15:36,889,204...37,101,299

G

mesoderm specific transcript

increases expression

benzo(k)fluoranthene results in increased expression of MEST mRNA

NCBI chr 7:130,486,175...130,506,465
Ensembl chr 7:130,486,171...130,506,465

G

meteorin like, glial cell differentiation regulator

decreases expression

benzo(k)fluoranthene results in decreased expression of METRNL mRNA

NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122

G

microfibril associated protein 4

increases expression

benzo(k)fluoranthene results in increased expression of MFAP4 mRNA

NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190

G

microfibril associated protein 5

decreases expression

benzo(k)fluoranthene results in decreased expression of MFAP5 mRNA

NCBI chr12:8,645,943...8,662,826
Ensembl chr12:8,637,346...8,662,888

G

milk fat globule EGF and factor V/VIII domain containing

increases expression

benzo(k)fluoranthene results in increased expression of MFGE8 mRNA

NCBI chr15:88,898,683...88,913,379
Ensembl chr15:88,898,683...88,913,468

G

multifunctional ROCO family signaling regulator 1

decreases expression

benzo(k)fluoranthene results in decreased expression of MFHAS1 mRNA

NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression

benzo(k)fluoranthene results in increased expression of MFSD2A mRNA

NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968

G

monoglyceride lipase

decreases expression

benzo(k)fluoranthene results in decreased expression of MGLL mRNA

NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190

G

microtubule associated monooxygenase, calponin and LIM domain containing 1

increases expression

benzo(k)fluoranthene results in increased expression of MICAL1 mRNA

NCBI chr 6:109,444,062...109,465,968
Ensembl chr 6:109,444,062...109,465,968

G

microRNA 1180

increases expression

benzo(k)fluoranthene results in increased expression of MIR1180 mRNA

NCBI chr17:19,344,506...19,344,574
Ensembl chr17:19,344,506...19,344,574

G

microRNA 1275

increases expression

benzo(k)fluoranthene results in increased expression of MIR1275 mRNA

NCBI chr 6:33,999,972...34,000,051
Ensembl chr 6:33,999,972...34,000,051

G

microRNA 1301

increases expression

benzo(k)fluoranthene results in increased expression of MIR1301 mRNA

NCBI chr 2:25,328,640...25,328,721
Ensembl chr 2:25,328,640...25,328,721

G

microRNA 181d

increases expression

benzo(k)fluoranthene results in increased expression of MIR181D mRNA

NCBI chr19:13,874,875...13,875,011
Ensembl chr19:13,874,875...13,875,011

G

microRNA 198

increases expression

benzo(k)fluoranthene results in increased expression of MIR198 mRNA

NCBI chr 3:120,395,668...120,395,729
Ensembl chr 3:120,395,668...120,395,729

G

microRNA 200c

increases expression

benzo(k)fluoranthene results in increased expression of MIR200C mRNA

NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766

G

microRNA 22

increases expression

benzo(k)fluoranthene results in increased expression of MIR22 mRNA

NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987

G

microRNA 221

increases expression

benzo(k)fluoranthene results in increased expression of MIR221 mRNA

NCBI chr X:45,746,157...45,746,266
Ensembl chr X:45,746,157...45,746,266

G

microRNA 23b

increases expression

benzo(k)fluoranthene results in increased expression of MIR23B mRNA

NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304

G

microRNA 33a

decreases expression

benzo(k)fluoranthene results in decreased expression of MIR33A mRNA

NCBI chr22:41,900,944...41,901,012
Ensembl chr22:41,900,944...41,901,012

G

microRNA 629

increases expression

benzo(k)fluoranthene results in increased expression of MIR629 mRNA

NCBI chr15:70,079,372...70,079,468
Ensembl chr15:70,079,372...70,079,468

G

microRNA 658

increases expression

benzo(k)fluoranthene results in increased expression of MIR658 mRNA

NCBI chr22:37,844,272...37,844,371
Ensembl chr22:37,844,272...37,844,371

G

microRNA let-7b

increases expression

benzo(k)fluoranthene results in increased expression of MIRLET7B mRNA

NCBI chr22:46,113,686...46,113,768
Ensembl chr22:46,113,686...46,113,768

G

monocyte to macrophage differentiation associated 2

decreases expression

benzo(k)fluoranthene results in decreased expression of MMD2 mRNA

NCBI chr 7:4,892,245...4,959,187
Ensembl chr 7:4,905,989...4,959,212

G

matrix metallopeptidase 1

increases expression
multiple interactions

benzo(k)fluoranthene results in increased expression of MMP1 mRNA
Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]

NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160

G

matrix metallopeptidase 13

increases expression

benzo(k)fluoranthene results in increased expression of MMP13 mRNA

NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732

G

matrix metallopeptidase 25

increases expression
multiple interactions

benzo(k)fluoranthene results in increased expression of MMP25 mRNA
Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP25 mRNA]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP25 mRNA]

NCBI chr16:3,046,561...3,060,726
Ensembl chr16:3,046,062...3,060,729

G

matrix metallopeptidase 8

increases expression

benzo(k)fluoranthene results in increased expression of MMP8 mRNA

NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050

G

molybdenum cofactor sulfurase

decreases expression

benzo(k)fluoranthene results in decreased expression of MOCOS mRNA

NCBI chr18:36,187,497...36,272,157
Ensembl chr18:36,187,497...36,272,157

G

molybdenum cofactor synthesis 2

decreases expression

benzo(k)fluoranthene results in decreased expression of MOCS2 mRNA

NCBI chr 5:53,095,679...53,109,757
Ensembl chr 5:53,095,679...53,110,063

G

monooxygenase DBH like 1

decreases expression

benzo(k)fluoranthene results in decreased expression of MOXD1 mRNA

NCBI chr 6:132,296,055...132,401,475
Ensembl chr 6:132,296,055...132,401,475

G

M-phase phosphoprotein 9

increases expression

benzo(k)fluoranthene results in increased expression of MPHOSPH9 mRNA

NCBI chr12:123,152,324...123,244,002
Ensembl chr12:123,152,320...123,244,014

G

myosin phosphatase Rho interacting protein

decreases expression

benzo(k)fluoranthene results in decreased expression of MPRIP mRNA

NCBI chr17:17,042,457...17,192,643
Ensembl chr17:17,042,457...17,217,679

G

melanoregulin

decreases expression

benzo(k)fluoranthene results in decreased expression of MREG mRNA

NCBI chr 2:215,939,308...216,034,096
Ensembl chr 2:215,942,584...216,034,096

G

membrane spanning 4-domains A4A

increases expression

benzo(k)fluoranthene results in increased expression of MS4A4A mRNA

NCBI chr11:60,280,666...60,308,970
Ensembl chr11:60,185,657...60,318,080

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

decreases expression

benzo(k)fluoranthene results in decreased expression of ND6 mRNA

NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673

G

myosin light chain 12A

decreases expression

benzo(k)fluoranthene results in decreased expression of MYL12A mRNA

NCBI chr18:3,247,482...3,256,237
Ensembl chr18:3,247,481...3,256,236

G

myosin light chain 7

decreases expression

benzo(k)fluoranthene results in decreased expression of MYL7 mRNA

NCBI chr 7:44,138,864...44,141,332
Ensembl chr 7:44,138,864...44,141,332

G

myosin light chain kinase

decreases expression

benzo(k)fluoranthene results in decreased expression of MYLK mRNA

NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332

G

neutrophil cytosolic factor 4

increases expression

benzo(k)fluoranthene results in increased expression of NCF4 mRNA

NCBI chr22:36,861,006...36,878,015
Ensembl chr22:36,860,988...36,878,017

G

natural cytotoxicity triggering receptor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of NCR1 mRNA

NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140

G

NDC80 kinetochore complex component

decreases expression

benzo(k)fluoranthene results in decreased expression of NDC80 mRNA

NCBI chr18:2,571,557...2,616,635
Ensembl chr18:2,571,557...2,616,635

G

nuclear paraspeckle assembly transcript 1

increases expression

benzo(k)fluoranthene results in increased expression of NEAT1 mRNA

NCBI chr11:65,422,798...65,445,540
Ensembl chr11:65,422,278...65,445,540

G

nebulin

increases expression

benzo(k)fluoranthene results in increased expression of NEB mRNA

NCBI chr 2:151,485,339...151,734,476
Ensembl chr 2:151,485,336...151,734,487

G

NEDD4 E3 ubiquitin protein ligase

decreases expression

benzo(k)fluoranthene results in decreased expression of NEDD4 mRNA

NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660

G

neuralized E3 ubiquitin protein ligase 3

increases expression

benzo(k)fluoranthene results in increased expression of NEURL3 mRNA

NCBI chr 2:96,497,646...96,508,109
Ensembl chr 2:96,497,646...96,508,109

G

nuclear factor of activated T cells 2

increases expression

benzo(k)fluoranthene results in increased expression of NFATC2 mRNA

NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831

G

NFE2 like bZIP transcription factor 2

increases expression

benzo(k)fluoranthene results in increased expression of NFE2L2 mRNA

NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756

G

NIPA like domain containing 2

decreases expression

benzo(k)fluoranthene results in decreased expression of NIPAL2 mRNA

NCBI chr 8:98,189,826...98,294,235
Ensembl chr 8:98,189,826...98,294,393

G

NLR family pyrin domain containing 10

decreases expression

benzo(k)fluoranthene results in decreased expression of NLRP10 mRNA

NCBI chr11:7,957,537...7,965,447
Ensembl chr11:7,957,537...7,965,447

G

neuromedin U

decreases expression

benzo(k)fluoranthene results in decreased expression of NMU mRNA

NCBI chr 4:55,595,231...55,636,793
Ensembl chr 4:55,595,229...55,636,698

G

neuronatin

decreases expression

benzo(k)fluoranthene results in decreased expression of NNAT mRNA

NCBI chr20:37,521,250...37,523,690
Ensembl chr20:37,521,206...37,523,690

G

nicotinamide N-methyltransferase

increases expression

benzo(k)fluoranthene results in increased expression of NNMT mRNA

NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536

G

NAD(P)H quinone dehydrogenase 1

increases expression

benzo(k)fluoranthene results in increased expression of NQO1 mRNA

PMID:17253728 PMID:26377693

NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668

G

nuclear receptor subfamily 1 group D member 2

increases expression

benzo(k)fluoranthene results in increased expression of NR1D2 mRNA

NCBI chr 3:23,945,286...23,980,617
Ensembl chr 3:23,945,286...23,980,637

G

netrin 1

increases expression

benzo(k)fluoranthene results in increased expression of NTN1 mRNA

NCBI chr17:9,003,087...9,244,000
Ensembl chr17:9,021,510...9,244,000

G

NUMB endocytic adaptor protein

decreases expression

benzo(k)fluoranthene results in decreased expression of NUMB mRNA

NCBI chr14:73,275,216...73,458,546
Ensembl chr14:73,275,107...73,466,167

G

olfactory receptor family 7 subfamily E member 24

decreases expression

benzo(k)fluoranthene results in decreased expression of OR7E178 mRNA

NCBI chr19:9,206,488...9,252,625
Ensembl chr19:9,247,344...9,252,625

G

oxysterol binding protein like 1A

decreases expression

benzo(k)fluoranthene results in decreased expression of OSBPL1A mRNA

NCBI chr18:24,162,045...24,397,824
Ensembl chr18:24,162,045...24,397,880

G

oxysterol binding protein like 3

increases expression

benzo(k)fluoranthene results in increased expression of OSBPL3 mRNA

NCBI chr 7:24,796,537...24,981,845
Ensembl chr 7:24,796,540...24,981,634

G

oxidative stress induced growth inhibitor family member 2

increases expression

benzo(k)fluoranthene results in increased expression of OSGIN2 mRNA

NCBI chr 8:89,901,868...89,927,888
Ensembl chr 8:89,901,849...89,927,888

G

oncostatin M receptor

decreases expression

benzo(k)fluoranthene results in decreased expression of OSMR mRNA

NCBI chr 5:38,846,012...38,945,579
Ensembl chr 5:38,845,858...38,945,596

G

purinergic receptor P2X 4

increases expression

benzo(k)fluoranthene results in increased expression of P2RX4 mRNA

NCBI chr12:121,210,129...121,234,106
Ensembl chr12:121,210,065...121,234,106

G

purinergic receptor P2X 7

increases expression

benzo(k)fluoranthene results in increased expression of P2RX7 mRNA

NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032

G

pyrimidinergic receptor P2Y6

increases expression

benzo(k)fluoranthene results in increased expression of P2RY6 mRNA

NCBI chr11:73,264,506...73,298,625
Ensembl chr11:73,264,498...73,305,103

G

peptidyl arginine deiminase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of PADI1 mRNA

NCBI chr 1:17,205,128...17,246,007
Ensembl chr 1:17,205,128...17,246,007

G

phenylalanine hydroxylase

decreases expression

benzo(k)fluoranthene results in decreased expression of PAH mRNA

NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410

G

pappalysin 1

increases expression

benzo(k)fluoranthene results in increased expression of PAPPA mRNA

NCBI chr 9:116,153,791...116,402,321
Ensembl chr 9:116,153,791...116,402,321

G

pappalysin 2

decreases expression

benzo(k)fluoranthene results in decreased expression of PAPPA2 mRNA

NCBI chr 1:176,463,175...176,845,601
Ensembl chr 1:176,463,171...176,845,601

G

par-3 family cell polarity regulator

decreases expression

benzo(k)fluoranthene results in decreased expression of PARD3 mRNA

NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325

G

poly(ADP-ribose) polymerase 1

increases cleavage

benzo(k)fluoranthene results in increased cleavage of PARP1 protein

NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154

G

paired box 2

decreases expression

benzo(k)fluoranthene results in decreased expression of PAX2 mRNA

NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944

G

protocadherin gamma subfamily A, 8

decreases expression

benzo(k)fluoranthene results in decreased expression of PCDHGA8 mRNA

NCBI chr 5:141,392,633...141,512,975
Ensembl chr 5:141,390,157...141,512,975

G

protocadherin gamma subfamily A, 9

increases expression

benzo(k)fluoranthene results in increased expression of PCDHGA9 mRNA

NCBI chr 5:141,402,778...141,512,975
Ensembl chr 5:141,402,778...141,512,975

G

Purkinje cell protein 4 like 1

increases expression

benzo(k)fluoranthene results in increased expression of PCP4L1 mRNA

NCBI chr 1:161,258,745...161,285,450
Ensembl chr 1:161,258,745...161,285,450

G

proprotein convertase subtilisin/kexin type 5

decreases expression

benzo(k)fluoranthene results in decreased expression of PCSK5 mRNA

NCBI chr 9:75,889,809...76,362,975
Ensembl chr 9:75,890,644...76,362,975

G

platelet derived growth factor receptor like

decreases expression

benzo(k)fluoranthene results in decreased expression of PDGFRL mRNA

NCBI chr 8:17,576,433...17,643,144
Ensembl chr 8:17,576,433...17,644,071

G

PDZ and LIM domain 2

decreases expression

benzo(k)fluoranthene results in decreased expression of PDLIM2 mRNA

NCBI chr 8:22,578,741...22,598,026
Ensembl chr 8:22,578,279...22,598,025

G

pyridoxal dependent decarboxylase domain containing 1

decreases expression

benzo(k)fluoranthene results in decreased expression of PDXDC1 mRNA

NCBI chr16:14,974,735...15,153,218
Ensembl chr16:14,974,591...15,153,671

G

PDZK1 interacting protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of PDZK1IP1 mRNA

NCBI chr 1:47,183,582...47,190,036
Ensembl chr 1:47,183,582...47,191,044

G

p53 apoptosis effector related to PMP22

decreases expression

benzo(k)fluoranthene results in decreased expression of PERP mRNA

NCBI chr 6:138,088,505...138,107,419
Ensembl chr 6:138,088,505...138,107,419

G

peptidoglycan recognition protein 2

decreases expression

benzo(k)fluoranthene results in decreased expression of PGLYRP2 mRNA

NCBI chr19:15,468,645...15,479,501
Ensembl chr19:15,468,645...15,498,956

G

phosphatidylinositol 4-kinase beta

increases expression

benzo(k)fluoranthene results in increased expression of PI4KB mRNA

NCBI chr 1:151,291,797...151,327,715
Ensembl chr 1:151,291,797...151,327,715

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

decreases expression

benzo(k)fluoranthene results in decreased expression of PIK3CB mRNA

NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,336...138,834,928

G

paired immunoglobin like type 2 receptor alpha

increases expression

benzo(k)fluoranthene results in increased expression of PILRA mRNA

NCBI chr 7:100,371,291...100,400,096
Ensembl chr 7:100,367,530...100,400,096

G

polycystin 1, transient receptor potential channel interacting

decreases expression

benzo(k)fluoranthene results in decreased expression of PKD1 mRNA

NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898

G

plakophilin 1

increases expression

benzo(k)fluoranthene results in increased expression of PKP1 mRNA

NCBI chr 1:201,283,506...201,332,989
Ensembl chr 1:201,283,452...201,332,993

G

phospholipase A2 group IVE

decreases expression

benzo(k)fluoranthene results in decreased expression of PLA2G4E mRNA

NCBI chr15:41,981,582...42,050,703
Ensembl chr15:41,981,394...42,051,190

G

PLAG1 like zinc finger 1

decreases expression

benzo(k)fluoranthene results in decreased expression of PLAGL1 mRNA

NCBI chr 6:143,940,300...144,064,599
Ensembl chr 6:143,940,300...144,064,599

G

pleckstrin homology domain containing A4

decreases expression

benzo(k)fluoranthene results in decreased expression of PLEKHA4 mRNA

NCBI chr19:48,837,097...48,868,617
Ensembl chr19:48,837,092...48,868,617

G

polo like kinase 2

increases expression

benzo(k)fluoranthene results in increased expression of PLK2 mRNA

NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139

G

pyridoxal phosphate binding protein

decreases expression

benzo(k)fluoranthene results in decreased expression of PLPBP mRNA

NCBI chr 8:37,762,546...37,779,768
Ensembl chr 8:37,762,595...37,779,768

G

phorbol-12-myristate-13-acetate-induced protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of PMAIP1 mRNA

NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305

G

phosphomannomutase 1

increases expression

benzo(k)fluoranthene results in increased expression of PMM1 mRNA

NCBI chr22:41,576,900...41,589,840
Ensembl chr22:41,576,900...41,589,871

G

phosphomevalonate kinase

decreases expression

benzo(k)fluoranthene results in decreased expression of PMVK mRNA

NCBI chr 1:154,924,740...154,942,658
Ensembl chr 1:154,924,740...154,936,719

G

RNA polymerase III subunit G

decreases expression

benzo(k)fluoranthene results in decreased expression of POLR3G mRNA

NCBI chr 5:90,473,929...90,514,557
Ensembl chr 5:90,471,748...90,514,557

G

paraoxonase 1

increases expression

benzo(k)fluoranthene results in increased expression of PON1 mRNA

NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532

G

peroxisome proliferator activated receptor alpha

increases expression

benzo(k)fluoranthene results in increased expression of PPARA mRNA

NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755

G

peroxisome proliferator activated receptor delta

increases expression

benzo(k)fluoranthene results in increased expression of PPARD mRNA

NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191

G

pro-platelet basic protein

increases expression

benzo(k)fluoranthene results in increased expression of PPBP mRNA

NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,985,966...73,988,276

G

periplakin

increases expression

benzo(k)fluoranthene results in increased expression of PPL mRNA

NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741

G

protein phosphatase 2 regulatory subunit Balpha

decreases expression

benzo(k)fluoranthene results in decreased expression of PPP2R2A mRNA

NCBI chr 8:26,291,508...26,372,680
Ensembl chr 8:26,291,508...26,372,680

G

PEAK1 related, kinase-activating pseudokinase 1

increases expression

benzo(k)fluoranthene results in increased expression of PRAG1 mRNA

NCBI chr 8:8,317,736...8,386,439
Ensembl chr 8:8,317,736...8,386,439

G

proteoglycan 4

increases expression

benzo(k)fluoranthene results in increased expression of PRG4 mRNA

NCBI chr 1:186,296,273...186,314,567
Ensembl chr 1:186,296,279...186,314,567

G

protein arginine methyltransferase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of PRMT1 mRNA

NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029

G

protein C receptor

increases expression

benzo(k)fluoranthene results in increased expression of PROCR mRNA

NCBI chr20:35,171,096...35,216,259
Ensembl chr20:35,172,072...35,216,240

G

proline dehydrogenase 1

increases expression

benzo(k)fluoranthene results in increased expression of PRODH mRNA

NCBI chr22:18,912,781...18,936,553
Ensembl chr22:18,912,777...18,936,553

G

serine protease 12

decreases expression

benzo(k)fluoranthene results in decreased expression of PRSS12 mRNA

NCBI chr 4:118,280,038...118,353,003
Ensembl chr 4:118,280,038...118,353,003

G

prostaglandin-endoperoxide synthase 2

decreases expression
increases expression
multiple interactions

benzo(k)fluoranthene results in decreased expression of PTGS2 protein
benzo(k)fluoranthene results in increased expression of PTGS2 mRNA
[Docosahexaenoic Acids co-treated with benzo(k)fluoranthene] results in increased expression of PTGS2 mRNA

PMID:25956473 PMID:26377693

NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922

G

protein tyrosine phosphatase non-receptor type 9

decreases expression

benzo(k)fluoranthene results in decreased expression of PTPN9 mRNA

NCBI chr15:75,463,251...75,579,315
Ensembl chr15:75,463,251...75,579,315

G

peptidyl-tRNA hydrolase 1 homolog

decreases expression

benzo(k)fluoranthene results in decreased expression of PTRH1 mRNA

NCBI chr 9:127,694,150...127,715,676
Ensembl chr 9:127,690,348...127,724,873

G

2-phosphoxylose phosphatase 1

increases expression

benzo(k)fluoranthene results in increased expression of PXYLP1 mRNA

NCBI chr 3:141,231,825...141,294,924
Ensembl chr 3:141,228,726...141,367,753

G

glutaminyl-peptide cyclotransferase

decreases expression

benzo(k)fluoranthene results in decreased expression of QPCT mRNA

NCBI chr 2:37,344,630...37,373,322
Ensembl chr 2:37,342,827...37,373,322

G

RAB24, member RAS oncogene family

decreases expression

benzo(k)fluoranthene results in decreased expression of RAB24 mRNA

NCBI chr 5:177,301,198...177,303,719
Ensembl chr 5:177,301,198...177,303,744

G

RAB5A, member RAS oncogene family

decreases expression

benzo(k)fluoranthene results in decreased expression of RAB5A mRNA

NCBI chr 3:19,947,097...19,985,175
Ensembl chr 3:19,947,097...19,985,175

G

RAD51 paralog B

increases expression

benzo(k)fluoranthene results in increased expression of RAD51B mRNA

NCBI chr14:67,819,779...68,683,096
Ensembl chr14:67,819,779...68,730,218

G

receptor activity modifying protein 3

increases expression

benzo(k)fluoranthene results in increased expression of RAMP3 mRNA

NCBI chr 7:45,157,791...45,184,250
Ensembl chr 7:45,157,791...45,186,302

G

recombination signal binding protein for immunoglobulin kappa J region like

decreases expression

benzo(k)fluoranthene results in decreased expression of RBPJL mRNA

NCBI chr20:45,306,840...45,317,824
Ensembl chr20:45,306,840...45,317,824

G

regenerating family member 3 gamma

increases expression

benzo(k)fluoranthene results in increased expression of REG3G mRNA

NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505

G

reelin

decreases expression

benzo(k)fluoranthene results in decreased expression of RELN mRNA

NCBI chr 7:103,471,789...103,989,658
Ensembl chr 7:103,471,381...103,989,658

G

retinol saturase

decreases expression

benzo(k)fluoranthene results in decreased expression of RETSAT mRNA

NCBI chr 2:85,341,955...85,354,528
Ensembl chr 2:85,341,955...85,354,531

G

regulator of G protein signaling 18

increases expression

benzo(k)fluoranthene results in increased expression of RGS18 mRNA

NCBI chr 1:192,158,462...192,185,815
Ensembl chr 1:192,158,462...192,185,815

G

regulator of G protein signaling 9

increases expression

benzo(k)fluoranthene results in increased expression of RGS9 mRNA

NCBI chr17:65,137,370...65,227,703
Ensembl chr17:65,100,812...65,227,703

G

Rh family B glycoprotein

decreases expression

benzo(k)fluoranthene results in decreased expression of RHBG mRNA

NCBI chr 1:156,369,211...156,385,219
Ensembl chr 1:156,369,211...156,385,219

G

ras homolog family member C

increases expression

benzo(k)fluoranthene results in increased expression of RHOC mRNA

NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434

G

ras homolog family member F, filopodia associated

decreases expression

benzo(k)fluoranthene results in decreased expression of RHOF mRNA

NCBI chr12:121,777,754...121,793,688
Ensembl chr12:121,777,754...121,803,403

G

ras homolog family member J

increases expression

benzo(k)fluoranthene results in increased expression of RHOJ mRNA

NCBI chr14:63,204,443...63,293,508
Ensembl chr14:63,204,114...63,293,508

G

RHO family interacting cell polarization regulator 2

increases expression

benzo(k)fluoranthene results in increased expression of RIPOR2 mRNA

NCBI chr 6:24,804,284...25,042,168
Ensembl chr 6:24,804,282...25,042,170

G

ring finger protein 227

decreases expression

benzo(k)fluoranthene results in decreased expression of RNF227 mRNA

NCBI chr17:7,913,324...7,916,318
Ensembl chr17:7,913,339...7,916,289

G

S100 calcium binding protein A16

decreases expression

benzo(k)fluoranthene results in decreased expression of S100A16 mRNA

NCBI chr 1:153,606,883...153,613,137
Ensembl chr 1:153,606,886...153,613,145

G

S100 calcium binding protein A8

increases expression

benzo(k)fluoranthene results in increased expression of S100A8 mRNA

NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073

G

S100 calcium binding protein A9

increases expression

benzo(k)fluoranthene results in increased expression of S100A9 mRNA

NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023

G

sphingosine-1-phosphate receptor 5

decreases expression

benzo(k)fluoranthene results in decreased expression of S1PR5 mRNA

NCBI chr19:10,512,742...10,517,965
Ensembl chr19:10,512,742...10,517,931

G

serum amyloid A3, pseudogene

increases expression

benzo(k)fluoranthene results in increased expression of SAA3 mRNA

NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132

G

sciellin

decreases expression

benzo(k)fluoranthene results in decreased expression of SCEL mRNA

NCBI chr13:77,535,706...77,645,263
Ensembl chr13:77,535,674...77,645,263

G

secretoglobin family 1A member 1

decreases expression

benzo(k)fluoranthene results in decreased expression of SCGB1A1 mRNA

NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195

G

secretoglobin family 3A member 1

increases expression

benzo(k)fluoranthene results in increased expression of SCGB3A1 mRNA

NCBI chr 5:180,590,105...180,591,499
Ensembl chr 5:180,590,105...180,591,499

G

short chain dehydrogenase/reductase family 16C member 6, pseudogene

decreases expression

benzo(k)fluoranthene results in decreased expression of SDR16C6 mRNA

NCBI chr 8:56,374,718...56,390,710
Ensembl chr 8:56,373,064...56,395,365
Ensembl chr 8:56,373,064...56,395,365

G

selenium binding protein 1

increases expression

benzo(k)fluoranthene results in increased expression of SELENBP1 mRNA

NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707

G

selenoprotein K

increases expression

benzo(k)fluoranthene results in increased expression of SELENOK mRNA

NCBI chr 3:53,884,417...53,891,859
Ensembl chr 3:53,884,417...53,891,885

G

semaphorin 3E

decreases expression

benzo(k)fluoranthene results in decreased expression of SEMA3E mRNA

NCBI chr 7:83,363,238...83,649,139
Ensembl chr 7:83,363,238...83,649,139

G

semaphorin 3G

decreases expression

benzo(k)fluoranthene results in decreased expression of SEMA3G mRNA

NCBI chr 3:52,433,035...52,445,103
Ensembl chr 3:52,433,035...52,445,103

G

septin 3

decreases expression

benzo(k)fluoranthene results in decreased expression of SEPTIN3 mRNA

NCBI chr22:41,969,443...41,998,221
Ensembl chr22:41,969,443...41,998,221

G

septin 8

increases expression

benzo(k)fluoranthene results in increased expression of SEPTIN8 mRNA

NCBI chr 5:132,750,819...132,780,083
Ensembl chr 5:132,750,819...132,807,241

G

serpin family B member 11

decreases expression

benzo(k)fluoranthene results in decreased expression of SERPINB11 mRNA

NCBI chr18:63,702,304...63,723,893
Ensembl chr18:63,647,579...63,726,432

G

serpin family B member 12

decreases expression

benzo(k)fluoranthene results in decreased expression of SERPINB12 mRNA

NCBI chr18:63,519,110...63,569,329
Ensembl chr18:63,542,369...63,569,329

G

serpin family B member 4

decreases expression

benzo(k)fluoranthene results in decreased expression of SERPINB3A mRNA

NCBI chr18:63,637,259...63,644,256
Ensembl chr18:63,637,259...63,644,256

G

serpin family B member 7

decreases expression

benzo(k)fluoranthene results in decreased expression of SERPINB7 mRNA

NCBI chr18:63,753,057...63,805,370
Ensembl chr18:63,752,935...63,805,376

G

serpin family E member 1

increases expression

benzo(k)fluoranthene results in increased expression of SERPINE1 mRNA

NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247

G

serpin family E member 2

decreases expression

benzo(k)fluoranthene results in decreased expression of SERPINE2 mRNA

NCBI chr 2:223,975,045...224,039,286
Ensembl chr 2:223,975,045...224,039,318

G

stratifin

decreases expression

benzo(k)fluoranthene results in decreased expression of SFN mRNA

NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456

G

SH2 domain containing 4A

increases expression

benzo(k)fluoranthene results in increased expression of SH2D4A mRNA

NCBI chr 8:19,313,693...19,396,218
Ensembl chr 8:19,313,693...19,396,218

G

SH3 domain binding glutamate rich protein like 2

decreases expression

benzo(k)fluoranthene results in decreased expression of SH3BGRL2 mRNA

NCBI chr 6:79,537,633...79,703,655
Ensembl chr 6:79,537,185...79,703,655

G

SH3 domain binding glutamate rich protein like 3

increases expression

benzo(k)fluoranthene results in increased expression of SH3BGRL3 mRNA

NCBI chr 1:26,280,086...26,281,522
Ensembl chr 1:26,280,086...26,281,522

G

SH3 domain binding protein 2

increases expression

benzo(k)fluoranthene results in increased expression of SH3BP2 mRNA

NCBI chr 4:2,793,085...2,841,096
Ensembl chr 4:2,793,023...2,841,291

G

SHC adaptor protein 3

decreases expression

benzo(k)fluoranthene results in decreased expression of SHC3 mRNA

NCBI chr 9:89,005,771...89,178,818
Ensembl chr 9:89,005,771...89,178,818

G

solute carrier family 10 member 6

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC10A6 mRNA

NCBI chr 4:86,823,468...86,849,384
Ensembl chr 4:86,823,468...86,849,384

G

solute carrier family 13 member 2

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC13A2 mRNA

NCBI chr17:28,473,644...28,497,781
Ensembl chr17:28,473,293...28,497,781

G

solute carrier family 13 member 5

increases expression

benzo(k)fluoranthene results in increased expression of SLC13A5 mRNA

NCBI chr17:6,684,719...6,713,369
Ensembl chr17:6,684,719...6,713,377

G

solute carrier family 1 member 2

increases expression

benzo(k)fluoranthene results in increased expression of SLC1A2 mRNA

NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063

G

solute carrier family 22 member 23

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC22A23 mRNA

NCBI chr 6:3,268,973...3,457,050
Ensembl chr 6:3,268,962...3,457,050

G

solute carrier family 2 member 3

increases expression

benzo(k)fluoranthene results in increased expression of SLC2A3 mRNA

NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007

G

solute carrier family 2 member 6

increases expression

benzo(k)fluoranthene results in increased expression of SLC2A6 mRNA

NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127

G

solute carrier family 30 member 4

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC30A4 mRNA

NCBI chr15:45,479,606...45,522,755
Ensembl chr15:45,479,606...45,522,755

G

solute carrier family 30 member 7

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC30A7 mRNA

NCBI chr 1:100,896,090...100,996,078
Ensembl chr 1:100,896,076...100,996,260

G

solute carrier family 43 member 1

increases expression

benzo(k)fluoranthene results in increased expression of SLC43A1 mRNA

NCBI chr11:57,484,534...57,515,702
Ensembl chr11:57,484,534...57,515,780

G

solute carrier family 46 member 1

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC46A1 mRNA

NCBI chr17:28,394,642...28,406,592
Ensembl chr17:28,394,642...28,407,197

G

solute carrier family 46 member 3

increases expression

benzo(k)fluoranthene results in increased expression of SLC46A3 mRNA

NCBI chr13:28,700,080...28,718,970
Ensembl chr13:28,700,064...28,718,970

G

solute carrier family 4 member 1 (Diego blood group)

increases expression

benzo(k)fluoranthene results in increased expression of SLC4A1 mRNA

NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141

G

solute carrier family 5 member 12

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC5A12 mRNA

NCBI chr11:26,667,020...26,723,389
Ensembl chr11:26,667,020...26,723,427

G

solute carrier family 66 member 1

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC66A1 mRNA

NCBI chr 1:19,312,326...19,334,463
Ensembl chr 1:19,312,326...19,329,300

G

solute carrier family 6 member 19

decreases expression

benzo(k)fluoranthene results in decreased expression of SLC6A19 mRNA

NCBI chr 5:1,201,595...1,225,111
Ensembl chr 5:1,201,595...1,225,111

G

sarcolipin

increases expression

benzo(k)fluoranthene results in increased expression of SLN mRNA

NCBI chr11:107,707,378...107,712,056
Ensembl chr11:107,707,378...107,719,693

G

SLX1 homolog A, structure-specific endonuclease subunit

decreases expression

benzo(k)fluoranthene results in decreased expression of SLX1B mRNA

NCBI chr16:30,193,843...30,197,566
Ensembl chr16:30,193,875...30,197,566

G

SLX4 interacting protein

increases expression

benzo(k)fluoranthene results in increased expression of SLX4IP mRNA

NCBI chr20:10,435,305...10,628,030
Ensembl chr20:10,435,305...10,636,829

G

SMAD family member 6

increases expression

benzo(k)fluoranthene results in increased expression of SMAD6 mRNA

NCBI chr15:66,702,236...66,782,849
Ensembl chr15:66,702,236...66,782,849

G

SWI/SNF related BAF chromatin remodeling complex subunit D3

increases expression

benzo(k)fluoranthene results in increased expression of SMARCD3 mRNA

NCBI chr 7:151,238,780...151,277,149
Ensembl chr 7:151,238,764...151,277,896

G

small integral membrane protein 5

increases expression

benzo(k)fluoranthene results in increased expression of SMIM5 mRNA

NCBI chr17:75,633,434...75,641,406
Ensembl chr17:75,633,434...75,641,404

G

sphingomyelin phosphodiesterase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of SMPD1 mRNA

NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,440...6,394,998

G

sphingomyelin phosphodiesterase 3

increases expression

benzo(k)fluoranthene results in increased expression of SMPD3 mRNA

NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508

G

snail family transcriptional repressor 1

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of SNAI1 mRNA]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of SNAI1 mRNA]

NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886

G

small nucleolar RNA host gene 11

decreases expression

benzo(k)fluoranthene results in decreased expression of SNHG11 mRNA

NCBI chr20:38,446,654...38,450,921
Ensembl chr20:38,446,343...38,450,943

G

small nucleolar RNA, H/ACA box 47

decreases expression

benzo(k)fluoranthene results in decreased expression of SNORA47 mRNA

NCBI chr 5:77,080,434...77,080,571
Ensembl chr 5:77,080,434...77,080,571

G

small nuclear ribonucleoprotein U11/U12 subunit 25

decreases expression

benzo(k)fluoranthene results in decreased expression of SNRNP25 mRNA

NCBI chr16:53,828...57,669
Ensembl chr16:53,828...57,669

G

sorbin and SH3 domain containing 3

decreases expression

benzo(k)fluoranthene results in decreased expression of SORBS3 mRNA

NCBI chr 8:22,544,973...22,575,788
Ensembl chr 8:22,544,986...22,575,788

G

SRY-box transcription factor 17

increases expression

benzo(k)fluoranthene results in increased expression of SOX17 mRNA

NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892

G

Sp5 transcription factor

increases expression

benzo(k)fluoranthene results in increased expression of SP5 mRNA

NCBI chr 2:170,715,337...170,718,078
Ensembl chr 2:170,715,337...170,718,078

G

Sp6 transcription factor

decreases expression

benzo(k)fluoranthene results in decreased expression of SP6 mRNA

NCBI chr17:47,844,908...47,876,311
Ensembl chr17:47,844,908...47,855,874

G

SPC25 component of NDC80 kinetochore complex

increases expression

benzo(k)fluoranthene results in increased expression of SPC25 mRNA

NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371

G

serine peptidase inhibitor Kazal type 1

increases expression

benzo(k)fluoranthene results in increased expression of SPINK1 mRNA

NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671

G

serine peptidase inhibitor Kazal type 4

increases expression

benzo(k)fluoranthene results in increased expression of SPINK4 mRNA

NCBI chr 9:33,240,167...33,248,567
Ensembl chr 9:33,218,365...33,248,567

G

sialophorin

decreases expression

benzo(k)fluoranthene results in decreased expression of SPN mRNA

NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876

G

spondin 2

decreases expression

benzo(k)fluoranthene results in decreased expression of SPON2 mRNA

NCBI chr 4:1,166,932...1,208,844
Ensembl chr 4:1,166,932...1,208,962

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signal peptide peptidase like 3

decreases expression

benzo(k)fluoranthene results in decreased expression of SPPL3 mRNA

NCBI chr12:120,762,510...120,904,358
Ensembl chr12:120,762,510...120,904,358

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small proline rich protein 1B

decreases expression

benzo(k)fluoranthene results in decreased expression of SPRR1B mRNA

NCBI chr 1:153,031,203...153,032,900
Ensembl chr 1:153,031,203...153,032,900

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serine palmitoyltransferase long chain base subunit 1

decreases response to substance
decreases expression

SPTLC1 protein mutant form results in decreased susceptibility to benzo(k)fluoranthene
benzo(k)fluoranthene results in decreased expression of SPTLC1 mRNA

PMID:16968971 PMID:26377693

NCBI chr 9:92,031,147...92,115,413
Ensembl chr 9:92,000,087...92,115,413

G

SLIT-ROBO Rho GTPase activating protein 3

decreases expression

benzo(k)fluoranthene results in decreased expression of SRGAP3 mRNA

NCBI chr 3:8,980,591...9,363,027
Ensembl chr 3:8,980,591...9,363,053

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signal recognition particle 68

increases expression

benzo(k)fluoranthene results in increased expression of SRP68 mRNA

NCBI chr17:76,038,785...76,072,517
Ensembl chr17:76,038,775...76,072,517

G

STT3 oligosaccharyltransferase complex catalytic subunit B

increases expression

benzo(k)fluoranthene results in increased expression of STT3B mRNA

NCBI chr 3:31,532,925...31,637,616
Ensembl chr 3:31,532,638...31,638,548

G

serine/threonine/tyrosine kinase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of STYK1 mRNA

NCBI chr12:10,618,923...10,674,052
Ensembl chr12:10,618,923...10,674,318

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sulfatase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of SULF1 mRNA

NCBI chr 8:69,466,781...69,660,912
Ensembl chr 8:69,466,624...69,660,915

G

sulfotransferase family 2A member 1

increases expression

benzo(k)fluoranthene results in increased expression of SULT2A1 mRNA

NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315

G

sushi domain containing 4

decreases expression

benzo(k)fluoranthene results in decreased expression of SUSD4 mRNA

NCBI chr 1:223,220,831...223,365,235
Ensembl chr 1:223,220,819...223,364,233

G

synaptonemal complex central element protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of SYCE1 mRNA

NCBI chr10:133,553,899...133,568,291
Ensembl chr10:133,553,901...133,569,835

G

tumor associated calcium signal transducer 2

decreases expression

benzo(k)fluoranthene results in decreased expression of TACSTD2 mRNA

NCBI chr 1:58,575,433...58,577,252
Ensembl chr 1:58,575,433...58,577,252

G

TATA-box binding protein associated factor 15

increases expression

benzo(k)fluoranthene results in increased expression of TAF15 mRNA

NCBI chr17:35,809,484...35,847,242
Ensembl chr17:35,809,482...35,864,615

G

Tax1 binding protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of TAX1BP1 mRNA

NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564

G

TBC1 domain family member 14

decreases expression

benzo(k)fluoranthene results in decreased expression of TBC1D14 mRNA

NCBI chr 4:6,909,466...7,033,114
Ensembl chr 4:6,909,242...7,033,118

G

titin-cap

increases expression

benzo(k)fluoranthene results in increased expression of TCAP mRNA

NCBI chr17:39,665,349...39,666,554
Ensembl chr17:39,665,349...39,666,554

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transcription elongation factor A like 8

increases expression

benzo(k)fluoranthene results in increased expression of TCEAL8 mRNA

NCBI chr X:103,252,995...103,255,155
Ensembl chr X:103,252,995...103,255,192

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transcription factor 4

increases expression

benzo(k)fluoranthene results in increased expression of TCF4 mRNA

NCBI chr18:55,222,185...55,635,957
Ensembl chr18:55,222,185...55,664,787

G

trefoil factor 1

increases expression

benzo(k)fluoranthene results in increased expression of TFF1 mRNA

NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535

G

trefoil factor 3

decreases expression

benzo(k)fluoranthene results in decreased expression of TFF3 mRNA

NCBI chr21:42,311,667...42,315,409
Ensembl chr21:42,311,667...42,315,409

G

transferrin receptor

increases expression

benzo(k)fluoranthene results in increased expression of TFRC mRNA

NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153

G

transforming growth factor beta 2

decreases expression

benzo(k)fluoranthene results in decreased expression of TGFB2 mRNA

NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619

G

transglutaminase 3

decreases expression

benzo(k)fluoranthene results in decreased expression of TGM3 mRNA

NCBI chr20:2,296,001...2,341,079
Ensembl chr20:2,296,001...2,341,079

G

thrombospondin 3

decreases expression

benzo(k)fluoranthene results in decreased expression of THBS3 mRNA

NCBI chr 1:155,195,588...155,209,178
Ensembl chr 1:155,195,588...155,209,051

G

thimet oligopeptidase 1

decreases expression

benzo(k)fluoranthene results in decreased expression of THOP1 mRNA

NCBI chr19:2,785,503...2,815,807
Ensembl chr19:2,785,503...2,815,807

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thrombospondin type 1 domain containing 1

affects expression

benzo(k)fluoranthene affects the expression of THSD1 mRNA

NCBI chr13:52,377,167...52,406,172
Ensembl chr13:52,377,167...52,416,373

G

TIMP metallopeptidase inhibitor 1

increases expression

benzo(k)fluoranthene results in increased expression of TIMP1 mRNA

NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789

G

TIMP metallopeptidase inhibitor 3

increases expression

benzo(k)fluoranthene results in increased expression of TIMP3 mRNA

NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041

G

tubulointerstitial nephritis antigen

increases expression

benzo(k)fluoranthene results in increased expression of TINAG mRNA

NCBI chr 6:54,307,862...54,390,142
Ensembl chr 6:54,307,859...54,390,142

G

TCDD inducible poly(ADP-ribose) polymerase

increases expression

benzo(k)fluoranthene results in increased expression of TIPARP mRNA

PMID:24472612 PMID:26377693

NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770

G

TLC domain containing 3A

decreases expression

benzo(k)fluoranthene results in decreased expression of TLCD3A mRNA

NCBI chr17:732,596...742,968
Ensembl chr17:732,412...742,968

G

TLC domain containing 4

increases expression

benzo(k)fluoranthene results in increased expression of TLCD4 mRNA

NCBI chr 1:95,092,517...95,197,607
Ensembl chr 1:95,117,355...95,197,607

G

TLE family member 1, transcriptional corepressor

decreases expression

benzo(k)fluoranthene results in decreased expression of TLE1 mRNA

NCBI chr 9:81,583,683...81,689,547
Ensembl chr 9:81,583,683...81,689,547

G

TLE family member 6, subcortical maternal complex member

decreases expression

benzo(k)fluoranthene results in decreased expression of TLE6 mRNA

NCBI chr19:2,977,401...2,995,179
Ensembl chr19:2,977,538...2,995,179

G

talin 2

decreases expression

benzo(k)fluoranthene results in decreased expression of TLN2 mRNA

NCBI chr15:62,390,550...62,844,631
Ensembl chr15:62,390,526...62,844,631

G

toll like receptor 12, pseudogene

increases expression

benzo(k)fluoranthene results in increased expression of TLR12 mRNA

NCBI chr 1:33,466,249...33,468,975
Ensembl chr 1:33,466,249...33,468,954

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transmembrane 7 superfamily member 2

decreases expression

benzo(k)fluoranthene results in decreased expression of TM7SF2 mRNA

NCBI chr11:65,111,872...65,116,230
Ensembl chr11:65,111,845...65,116,384

G

transmembrane and coiled-coil domain family 3

decreases expression

benzo(k)fluoranthene results in decreased expression of TMCC3 mRNA

NCBI chr12:94,567,122...94,650,557
Ensembl chr12:94,567,122...94,650,557

G

transmembrane protein 126B

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM126B mRNA

NCBI chr11:85,628,573...85,636,540
Ensembl chr11:85,628,573...85,636,539

G

transmembrane protein 14A

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM14A mRNA

NCBI chr 6:52,671,113...52,686,588
Ensembl chr 6:52,671,113...52,686,588

G

transmembrane protein 213

increases expression

benzo(k)fluoranthene results in increased expression of TMEM213 mRNA

NCBI chr 7:138,797,994...138,806,759
Ensembl chr 7:138,797,952...138,838,101

G

transmembrane protein 215

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM215 mRNA

NCBI chr 9:32,783,540...32,789,201
Ensembl chr 9:32,783,540...32,789,201

G

transmembrane protein 221

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM221 mRNA

NCBI chr19:17,435,509...17,448,668
Ensembl chr19:17,435,509...17,448,668

G

transmembrane protein 229B

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM229B mRNA

NCBI chr14:67,470,269...67,533,850
Ensembl chr14:67,447,084...67,533,739

G

transmembrane protein 40

increases expression

benzo(k)fluoranthene results in increased expression of TMEM40 mRNA

NCBI chr 3:12,733,528...12,769,457
Ensembl chr 3:12,733,528...12,769,457

G

transmembrane protein 45A

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM45A mRNA

NCBI chr 3:100,492,619...100,577,444
Ensembl chr 3:100,492,619...100,577,444

G

transmembrane protein 50B

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM50B mRNA

NCBI chr21:33,432,486...33,479,974
Ensembl chr21:33,432,485...33,479,974

G

transmembrane protein 86A

decreases expression

benzo(k)fluoranthene results in decreased expression of TMEM86A mRNA

NCBI chr11:18,698,779...18,704,785
Ensembl chr11:18,693,122...18,704,785

G

tropomodulin 4

increases expression

benzo(k)fluoranthene results in increased expression of TMOD4 mRNA

NCBI chr 1:151,169,987...151,175,981
Ensembl chr 1:151,169,986...151,176,284

G

transmembrane serine protease 11A

decreases expression

benzo(k)fluoranthene results in decreased expression of TMPRSS11A mRNA

NCBI chr 4:67,909,395...67,963,493
Ensembl chr 4:67,909,395...67,964,140

G

transmembrane serine protease 11F

decreases expression

benzo(k)fluoranthene results in decreased expression of TMPRSS11F mRNA

NCBI chr 4:68,053,198...68,129,869
Ensembl chr 4:68,053,198...68,129,869

G

tumor protein p53

affects activity

benzo(k)fluoranthene affects the activity of TP53 protein; benzo(k)fluoranthene metabolite affects the activity of TP53 protein

NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546

G

tribbles pseudokinase 3

decreases expression

benzo(k)fluoranthene results in decreased expression of TRIB3 mRNA

NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559

G

TMF1 regulated nuclear protein 1

decreases expression

benzo(k)fluoranthene results in decreased expression of TRNP1 mRNA

NCBI chr 1:26,993,692...27,000,886
Ensembl chr 1:26,993,692...27,001,912

G

tetraspanin 13

increases expression

benzo(k)fluoranthene results in increased expression of TSPAN13 mRNA

NCBI chr 7:16,753,755...16,784,536
Ensembl chr 7:16,753,755...16,784,536

G

tetraspanin 18

increases expression

benzo(k)fluoranthene results in increased expression of TSPAN18 mRNA

NCBI chr11:44,726,310...44,932,423
Ensembl chr11:44,726,465...44,932,423

G

tetraspanin 4

increases expression

benzo(k)fluoranthene results in increased expression of TSPAN4 mRNA

NCBI chr11:842,852...867,111
Ensembl chr11:842,812...867,116

G

tetraspanin 8

decreases expression

benzo(k)fluoranthene results in decreased expression of TSPAN8 mRNA

NCBI chr12:71,125,096...71,157,999
Ensembl chr12:71,125,085...71,441,898

G

tetratricopeptide repeat domain 39A

increases expression

benzo(k)fluoranthene results in increased expression of TTC39A mRNA

NCBI chr 1:51,287,258...51,345,116
Ensembl chr 1:51,287,258...51,345,116

G

tubulin alpha 8

increases expression

benzo(k)fluoranthene results in increased expression of TUBA8 mRNA

NCBI chr22:18,110,809...18,131,732
Ensembl chr22:18,110,100...18,146,683

G

tubulin beta 2A class IIa

decreases expression

benzo(k)fluoranthene results in decreased expression of TUBB2A mRNA

NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544

G

tubulin beta 6 class V

increases expression

benzo(k)fluoranthene results in increased expression of TUBB6 mRNA

NCBI chr18:12,307,669...12,329,826
Ensembl chr18:12,307,669...12,344,320

G

taurine up-regulated 1

decreases expression

benzo(k)fluoranthene results in decreased expression of TUG1 mRNA

NCBI chr22:30,969,265...30,979,395
Ensembl chr22:30,969,245...30,979,395

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tumor suppressor candidate 3

decreases expression

benzo(k)fluoranthene results in decreased expression of TUSC3 mRNA

NCBI chr 8:15,417,188...15,852,091
Ensembl chr 8:15,417,215...15,766,649

G

transmembrane immune signaling adaptor TYROBP

increases expression

benzo(k)fluoranthene results in increased expression of TYROBP mRNA

NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295

G

ubiquitin conjugating enzyme E2 D3

decreases expression

benzo(k)fluoranthene results in decreased expression of UBE2D3 mRNA

NCBI chr 4:102,794,383...102,868,895
Ensembl chr 4:102,794,383...102,868,896

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ubiquitin like 3

decreases expression

benzo(k)fluoranthene results in decreased expression of UBL3 mRNA

NCBI chr13:29,764,371...29,850,617
Ensembl chr13:29,764,371...29,850,617

G

ubiquilin 1

decreases expression

benzo(k)fluoranthene results in decreased expression of UBQLN1 mRNA

NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958

G

UDP-glucose ceramide glucosyltransferase

decreases expression

benzo(k)fluoranthene results in decreased expression of UGCG mRNA

NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369

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UDP glucuronosyltransferase family 1 member A6

increases expression
multiple interactions

benzo(k)fluoranthene results in increased expression of UGT1A6 mRNA
[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA

NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300

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UDP glucuronosyltransferase family 1 member A7

multiple interactions

[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A7 mRNA

NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300

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unc-5 netrin receptor B

increases expression

benzo(k)fluoranthene results in increased expression of UNC5B mRNA

NCBI chr10:71,212,570...71,302,864
Ensembl chr10:71,212,570...71,302,864

G

uroplakin 1A

decreases expression

benzo(k)fluoranthene results in decreased expression of UPK1A mRNA

NCBI chr19:35,666,517...35,678,481
Ensembl chr19:35,666,517...35,678,481

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ubiquitin specific peptidase 2

increases expression

benzo(k)fluoranthene results in increased expression of USP2 mRNA

NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711

G

ubiquitin specific peptidase 25

decreases expression

benzo(k)fluoranthene results in decreased expression of USP25 mRNA

NCBI chr21:15,729,982...15,880,064
Ensembl chr21:15,729,982...15,880,064

G

vasohibin 1

decreases expression

benzo(k)fluoranthene results in decreased expression of VASH1 mRNA

NCBI chr14:76,761,468...76,783,015
Ensembl chr14:76,761,468...76,783,015

G

vav guanine nucleotide exchange factor 3

decreases expression

benzo(k)fluoranthene results in decreased expression of VAV3 mRNA

NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180

G

VCP nuclear cofactor family member 1

decreases expression

benzo(k)fluoranthene results in decreased expression of VCF2 mRNA

NCBI chr17:73,207,353...73,232,394
Ensembl chr17:73,207,353...73,236,753

G

vasoactive intestinal peptide receptor 1

decreases expression

benzo(k)fluoranthene results in decreased expression of VIPR1 mRNA

NCBI chr 3:42,489,299...42,537,568
Ensembl chr 3:42,489,299...42,537,573

G

VPS16 core subunit of CORVET and HOPS complexes

increases expression

benzo(k)fluoranthene results in increased expression of VPS16 mRNA

NCBI chr20:2,840,745...2,866,732
Ensembl chr20:2,840,703...2,866,732

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V-set and immunoglobulin domain containing 10 like

decreases expression

benzo(k)fluoranthene results in decreased expression of VSIG10L mRNA

NCBI chr19:51,331,541...51,342,139
Ensembl chr19:51,331,536...51,342,139

G

WD repeat domain 86

decreases expression

benzo(k)fluoranthene results in decreased expression of WDR86 mRNA

NCBI chr 7:151,368,955...151,410,712
Ensembl chr 7:151,375,909...151,410,727

G

Wnt family member 10B

decreases expression

benzo(k)fluoranthene results in decreased expression of WNT10B mRNA

NCBI chr12:48,965,340...48,971,735
Ensembl chr12:48,965,340...48,971,735

G

Wnt family member 4

decreases expression

benzo(k)fluoranthene results in decreased expression of WNT4 mRNA

NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969

G

XK related X-linked

decreases expression

benzo(k)fluoranthene results in decreased expression of XKRX mRNA

NCBI chr X:100,886,916...100,959,343
Ensembl chr X:100,913,445...100,929,433

G

Y-box binding protein 1

increases expression

benzo(k)fluoranthene results in increased expression of YBX1 mRNA

NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805

G

zinc finger CCHC-type containing 14

decreases expression

benzo(k)fluoranthene results in decreased expression of ZCCHC14 mRNA

NCBI chr16:87,406,248...87,493,024
Ensembl chr16:87,406,246...87,493,024

G

zinc finger MYND-type containing 15

decreases expression

benzo(k)fluoranthene results in decreased expression of ZMYND15 mRNA

NCBI chr17:4,739,833...4,746,119
Ensembl chr17:4,739,833...4,746,119

G

zinc finger protein 467

increases expression

benzo(k)fluoranthene results in increased expression of ZFP467 mRNA

NCBI chr 7:149,764,182...149,776,530
Ensembl chr 7:149,764,182...149,773,588

G

zinc finger protein 644

decreases expression

benzo(k)fluoranthene results in decreased expression of ZFP644 mRNA

NCBI chr 1:90,915,304...91,022,035
Ensembl chr 1:90,915,298...91,022,272

G

zinc finger protein 706

decreases expression

benzo(k)fluoranthene results in decreased expression of ZFP706 mRNA

NCBI chr 8:101,197,052...101,206,222
Ensembl chr 8:101,177,878...101,206,193

G

zinc finger protein 750

decreases expression

benzo(k)fluoranthene results in decreased expression of ZFP750 mRNA

NCBI chr17:82,829,434...82,840,022
Ensembl chr17:82,829,434...82,840,022

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	26503
chemical entity	26483
molecular entity	26465
polyatomic entity	26301
molecule	25409
cyclic compound	24428
bicyclic compound	18702
carbobicyclic compound	5995
naphthalenes	3851
Benzo[k]fluoranthene	624
Path 2
Term	Annotations
CHEBI ontology	26503
subatomic particle	26479
composite particle	26479
hadron	26479
baryon	26479
nucleon	26479
atomic nucleus	26479
atom	26479
main group element atom	26217
p-block element atom	26217
carbon group element atom	25662
carbon atom	25624
organic molecular entity	25624
organic molecule	25368
organic cyclic compound	24427
carbocyclic compound	22187
carbopolycyclic compound	19889
carbobicyclic compound	5995
naphthalenes	3851
Benzo[k]fluoranthene	624

paths to the root