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Gene: DHX15 (DEAH-box helicase 15) Homo sapiens
Symbol: DHX15
Name: DEAH-box helicase 15
Description: Exhibits double-stranded RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Localizes to U12-type spliceosomal complex and nuclear speck. Colocalizes with U2-type post-mRNA release spliceosomal complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent RNA helicase #46; DBP1; DDX15; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15; DEAD/H box-15; DEAH (Asp-Glu-Ala-His) box helicase 15; DEAH (Asp-Glu-Ala-His) box polypeptide 15; DEAH box protein 15; HRH2; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; PRP43; PRPF43; PrPp43p; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; RNA helicase 2
Mus musculus (house mouse) : Dhx15 (DEAH (Asp-Glu-Ala-His) box polypeptide 15)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dhx15 (DEAH-box helicase 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dhx15 (DEAH-box helicase 15)
Pan paniscus (bonobo/pygmy chimpanzee) : DHX15 (DEAH-box helicase 15)
Canis lupus familiaris (dog) : DHX15 (DEAH-box helicase 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhx15 (DEAH-box helicase 15)
Sus scrofa (pig) : DHX15 (DEAH-box helicase 15)
Chlorocebus sabaeus (African green monkey) : DHX15 (DEAH-box helicase 15)
Heterocephalus glaber (naked mole-rat) : Dhx15 (DEAH-box helicase 15)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl424,517,441 - 24,584,554 (-)EnsemblGRCh38hg38GRCh38
GRCh38424,527,475 - 24,584,554 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37424,529,087 - 24,586,184 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36424,138,185 - 24,195,282 (-)NCBINCBI36hg18NCBI36
Build 34424,205,369 - 24,262,446NCBI
Celera424,978,492 - 25,035,556 (-)NCBI
Cytogenetic Map4p15.2NCBI
HuRef423,871,170 - 23,928,446 (-)NCBIHuRef
CHM1_1424,528,443 - 24,585,513 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DHX15
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317633
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.