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Gene: HEBP2 (heme binding protein 2) Homo sapiens
Symbol: HEBP2
Name: heme binding protein 2
Description: Predicted to have heme binding activity. Involved in negative regulation of mitochondrial membrane potential; positive regulation of mitochondrial membrane permeability; and positive regulation of necrotic cell death. Localizes to the mitochondrion.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C6orf34; C6ORF34B; heme-binding protein 2; KIAA1244; placental protein 23; PP23; RP3-422G23.1; SOUL
Mus musculus (house mouse) : Hebp2 (heme binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hebp2 (heme binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hebp2 (heme binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HEBP2 (heme binding protein 2)
Canis lupus familiaris (dog) : HEBP2 (heme binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hebp2 (heme binding protein 2)
Sus scrofa (pig) : HEBP2 (heme binding protein 2)
more info ...
Related Pseudogenes: HEBP2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6138,403,531 - 138,422,197 (+)Ensembl
GRCh386138,403,531 - 138,422,197 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376138,725,336 - 138,734,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366138,767,029 - 138,776,275 (+)NCBINCBI36hg18NCBI36
Build 346138,767,028 - 138,776,275NCBI
Celera6139,465,471 - 139,474,717 (+)NCBI
Cytogenetic Map6q24.1NCBI
HuRef6136,286,749 - 136,295,995 (+)NCBIHuRef
CHM1_16138,987,973 - 138,997,219 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HEBP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323071
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.