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Gene: YBX1 (Y-box binding protein 1) Homo sapiens
Symbol: YBX1
Name: Y-box binding protein 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; GTPase binding activity; and nucleic acid binding activity. Involved in RNA transport; positive regulation of gene expression; and protein localization to cytoplasmic stress granule. Localizes to several cellular components, including CRD-mediated mRNA stability complex; cytoplasmic stress granule; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BP-8; CBF-A; CCAAT-binding transcription factor I subunit A; CSDA2; CSDB; DBPB; DNA-binding protein B; EFI-A; enhancer factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; MDR-NF1; MGC104858; MGC110976; MGC117250; NSEP-1; NSEP1; nuclease sensitive element binding protein 1; nuclease-sensitive element-binding protein 1; Y box binding protein 1; Y-box transcription factor; Y-box-binding protein 1; YB-1; YB1
Mus musculus (house mouse) : Ybx1 (Y box protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ybx1 (Y box binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ybx1 (Y-box binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : YBX1 (Y-box binding protein 1)
Canis lupus familiaris (dog) : YBX1 (Y-box binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ybx1 (Y-box binding protein 1)
Sus scrofa (pig) : YBX1 (Y-box binding protein 1)
Chlorocebus sabaeus (African green monkey) : YBX1 (Y-box binding protein 1)
Heterocephalus glaber (naked mole-rat) : Ybx1 (Y-box binding protein 1)
more info ...
Related Pseudogenes: YBX1P1   YBX1P10   YBX1P2   YBX1P3   YBX1P4   YBX1P5   YBX1P6   YBX1P7   YBX1P8   YBX1P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl142,682,418 - 42,703,805 (+)EnsemblGRCh38hg38GRCh38
GRCh38142,682,418 - 42,703,805 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37143,148,060 - 43,168,024 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36142,920,653 - 42,940,607 (+)NCBINCBI36hg18NCBI36
Build 34142,817,216 - 42,837,113NCBI
Celera141,429,993 - 41,449,949 (+)NCBI
Cytogenetic Map1p34.2NCBI
HuRef141,268,237 - 41,268,497 (+)NCBIHuRef
HuRef141,269,041 - 41,287,988 (+)NCBIHuRef
CHM1_1143,264,764 - 43,286,335 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on YBX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732883
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.